KEGG   PATHWAY: hai04070
Entry
hai04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Hipposideros armiger (great roundleaf bat)
Class
Environmental Information Processing; Signal transduction
Pathway map
hai04070  Phosphatidylinositol signaling system
hai04070

Organism
Hipposideros armiger (great roundleaf bat) [GN:hai]
Gene
109371226  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
109371228  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
109372230  CALM3; calmodulin [KO:K02183]
109372271  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
109372273  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
109372316  [KO:K04959]
109372436  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
109372505  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
109372681  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
109372960  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
109373573  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
109373811  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
109374510  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
109374851  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
109375054  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
109375600  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
109375931  IP6K1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
109376449  TMEM55B; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
109376712  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
109376793  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
109376974  [KO:K00920] [EC:2.7.1.149]
109377471  SACM1L; phosphatidylinositide phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
109377792  [KO:K00915] [EC:2.7.1.140 2.7.1.151]
109378365  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
109378976  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [KO:K05858] [EC:3.1.4.11]
109378977  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
109379699  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
109379770  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
109379805  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
109379925  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
109380289  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
109380340  [KO:K02183]
109380396  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
109380562  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
109380619  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
109380798  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
109380957  [KO:K05860] [EC:3.1.4.11]
109381238  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
109382414  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
109382484  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
109382670  CALM1; calmodulin [KO:K02183]
109382688  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
109382999  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
109383054  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
109383559  INPP5A; type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01106] [EC:3.1.3.56]
109383603  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
109383794  [KO:K02183]
109383796  [KO:K02183]
109383841  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
109383962  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
109383976  PLCB2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
109384033  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
109384329  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
109385184  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
109385991  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
109386461  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
109386578  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
109386839  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
109387291  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
109387515  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
109387530  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
109387821  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
109387919  CDS1; phosphatidate cytidylyltransferase 1 isoform X1 [KO:K00981] [EC:2.7.7.41]
109388111  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
109388303  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
109388535  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
109388601  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
109388879  OCRL; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
109389917  CALM2; calmodulin [KO:K02183]
109390071  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
109390226  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
109390549  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
109390752  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
109390904  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
109390984  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
109391149  CALML6; calmodulin-like protein 6 [KO:K02183]
109391452  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
109391922  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
109392391  IP6K3; inositol hexakisphosphate kinase 3 isoform X1 [KO:K07756] [EC:2.7.4.21]
109392407  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
109392539  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
109393516  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
109394108  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
109394176  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
109394456  IMPAD1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
109394579  MTMR7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
109394871  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
109394976  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
109395800  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
109395865  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
109396233  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
109396239  MTM1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
109396857  DGKG; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
109396879  DGKA; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
109396934  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
hai04020  Calcium signaling pathway
hai04144  Endocytosis
hai04151  PI3K-Akt signaling pathway
hai04510  Focal adhesion
KO pathway
ko04070   

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