KEGG   PATHWAY: cang04144
Entry
cang04144                   Pathway                                
Name
Endocytosis - Colobus angolensis palliatus (Angola colobus)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
cang04144  Endocytosis
cang04144

Other DBs
GO: 0006897
Organism
Colobus angolensis palliatus (Angola colobus) [GN:cang]
Gene
105522395  ARF6; ADP-ribosylation factor 6 [KO:K07941]
105508867  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
105516620  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
105512821  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [KO:K00889] [EC:2.7.1.68]
105523669  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
105510990  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
105504166  DNM1; dynamin-1 [KO:K01528] [EC:3.6.5.5]
105526347  DNM3; dynamin-3 isoform X1 [KO:K01528] [EC:3.6.5.5]
105520855  DNM2; dynamin-2 [KO:K23484] [EC:3.6.5.5]
105509911  CLTA; clathrin light chain A isoform X1 [KO:K04644]
105515101  CLTB; clathrin light chain B isoform X1 [KO:K04645]
105523730  CLTCL1; clathrin heavy chain 2 [KO:K04646]
105520084  CLTC; clathrin heavy chain 1 isoform X1 [KO:K04646]
105514858  AP2A1; AP-2 complex subunit alpha-1 [KO:K11824]
105503214  AP2A2; AP-2 complex subunit alpha-2 [KO:K11824]
105518745  AP2B1; AP-2 complex subunit beta isoform X1 [KO:K11825]
105514469  AP2M1; AP-2 complex subunit mu isoform X1 [KO:K11826]
105526848  AP2S1; AP-2 complex subunit sigma isoform X1 [KO:K11827]
105500745  EHD2; EH domain-containing protein 2 [KO:K12469]
105509956  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
105525773  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
105506257  ZFYVE16; zinc finger FYVE domain-containing protein 16 [KO:K04679]
105500740  ZFYVE9; zinc finger FYVE domain-containing protein 9 [KO:K04679]
105505178  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
105517011  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
105510522  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
105525564  TFRC; transferrin receptor protein 1 [KO:K06503]
105500265  EGFR; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
105523780  PDGFRA; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
105503366  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
105508015  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
105515122  FGFR4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
105523056  IGF1R; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
105501218  CBL; E3 ubiquitin-protein ligase CBL [KO:K04707] [EC:2.3.2.27]
105519581  CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 [KO:K22517] [EC:2.3.2.27]
105526908  CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1 [KO:K22518] [EC:2.3.2.27]
105510425  SH3KBP1; SH3 domain-containing kinase-binding protein 1 isoform X1 [KO:K12470]
105503471  SH3GL2; endophilin-A1 isoform X1 [KO:K11247]
105512839  SH3GL1; endophilin-A2 [KO:K11247]
105520258  SH3GL3; endophilin-A3 isoform X1 [KO:K11247]
105521771  SH3GLB1; endophilin-B1 isoform X1 [KO:K11248]
105504036  SH3GLB2; endophilin-B2 [KO:K21269]
105511517  BIN1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
105513602  AMPH; amphiphysin isoform X1 [KO:K12562]
105524664  EPN3; epsin-3 [KO:K12471]
105504848  EPN1; epsin-1 isoform X1 [KO:K12471]
105520994  EPN2; epsin-2 [KO:K12471]
105510758  LOW QUALITY PROTEIN: epidermal growth factor receptor substrate 15-like 1 [KO:K12472]
105500389  EPS15L1; epidermal growth factor receptor substrate 15-like 1 [KO:K12472]
105500661  EPS15; epidermal growth factor receptor substrate 15 isoform X1 [KO:K12472]
105512544  SPG20; spartin [KO:K19366]
105510638  NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 [KO:K10591] [EC:2.3.2.26]
105517149  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [KO:K13305] [EC:2.3.2.26]
105502659  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
105510802  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
105500552  RNF41; E3 ubiquitin-protein ligase NRDP1 isoform X1 [KO:K11981] [EC:2.3.2.27]
105524200  ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 [KO:K05632] [EC:2.3.2.26]
105503018  SMURF2; E3 ubiquitin-protein ligase SMURF2 [KO:K04678] [EC:2.3.2.26]
105513113  SMURF1; E3 ubiquitin-protein ligase SMURF1 [KO:K04678] [EC:2.3.2.26]
105508251  WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
105501632  LOW QUALITY PROTEIN: NEDD4-like E3 ubiquitin-protein ligase WWP1 [KO:K05633] [EC:2.3.2.26]
105520939  LDLR; low-density lipoprotein receptor [KO:K12473]
105521465  LDLRAP1; low density lipoprotein receptor adapter protein 1 [KO:K12474]
105513519  DAB2; disabled homolog 2 isoform X1 [KO:K12475]
105509776  CCR5; C-C chemokine receptor type 5 [KO:K04180]
105504737  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
105504738  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
105508802  CXCR4; C-X-C chemokine receptor type 4 isoform X1 [KO:K04189]
105523305  GRK7; G protein-coupled receptor kinase 7 [KO:K00909] [EC:2.7.11.14]
105505934  GRK1; rhodopsin kinase [KO:K00909] [EC:2.7.11.14]
105512098  ADRBK1; beta-adrenergic receptor kinase 1 [KO:K00910] [EC:2.7.11.15]
105506642  ADRBK2; beta-adrenergic receptor kinase 2 isoform X1 [KO:K00910] [EC:2.7.11.15]
105515133  GRK6; G protein-coupled receptor kinase 6 isoform X1 [KO:K08291] [EC:2.7.11.16]
105503381  GRK5; G protein-coupled receptor kinase 5 isoform X1 [KO:K08291] [EC:2.7.11.16]
105507028  GRK4; G protein-coupled receptor kinase 4 isoform X1 [KO:K08291] [EC:2.7.11.16]
105523666  ARRB2; beta-arrestin-2 [KO:K04439]
105511822  ARRB1; beta-arrestin-1 [KO:K04439]
105518663  WASL; neural Wiskott-Aldrich syndrome protein [KO:K23612]
105514255  ACTR2; actin-related protein 2 [KO:K17260]
105508776  ACTR3; actin-related protein 3 isoform X1 [KO:K18584]
105511357  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
105513054  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
105513115  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
105500666  actin-related protein 2/3 complex subunit 1A isoform X1 [KO:K05757]
105504736  ARPC2; actin-related protein 2/3 complex subunit 2 isoform X1 [KO:K05758]
105508248  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
105527529  actin-related protein 2/3 complex subunit 3 [KO:K05756]
105504102  ARPC5L; LOW QUALITY PROTEIN: actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
105506123  ARPC5; actin-related protein 2/3 complex subunit 5 isoform X1 [KO:K05754]
105503098  WIPF2; WAS/WASL-interacting protein family member 2 isoform X1 [KO:K19475]
105513152  WIPF1; WAS/WASL-interacting protein family member 1 isoform X1 [KO:K19475]
105520317  WIPF3; WAS/WASL-interacting protein family member 3 [KO:K19475]
105501155  HSPA8; heat shock cognate 71 kDa protein isoform X1 [KO:K03283]
105519603  HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
105513758  HSPA1A; heat shock 70 kDa protein 1A/1B isoform X1 [KO:K03283]
105513759  HSPA1L; heat shock 70 kDa protein 1-like [KO:K03283]
105510791  DNAJC6; putative tyrosine-protein phosphatase auxilin isoform X1 [KO:K09526]
105507003  KIAA1033; WASH complex subunit 7 isoform X1 [KO:K18465]
105509082  KIAA0196; WASH complex subunit strumpellin isoform X1 [KO:K18464]
105517729  WASH complex subunit FAM21B-like [KO:K18462]
105522587  WAS protein family homolog 2 isoform X1 [KO:K18461]
105506711  CCDC53; WASH complex subunit CCDC53 isoform X1 [KO:K18463]
105508552  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
105505350  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
105520829  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
105506019  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
105507760  VPS29; vacuolar protein sorting-associated protein 29 isoform X1 [KO:K18467]
105501257  VPS26A; vacuolar protein sorting-associated protein 26A [KO:K18466]
105506523  VPS26B; vacuolar protein sorting-associated protein 26B [KO:K18466]
105525876  VPS35; vacuolar protein sorting-associated protein 35 isoform X1 [KO:K18468]
105512615  SNX12; sorting nexin-12 isoform X1 [KO:K17918]
105519469  SNX3; sorting nexin-3 isoform X1 [KO:K17918]
105502205  USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1 [KO:K11839] [EC:3.4.19.12]
105514581  STAMBP; STAM-binding protein [KO:K11866] [EC:3.4.19.12]
105517941  RAB7A; ras-related protein Rab-7a isoform X1 [KO:K07897]
105525458  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate [KO:K12182]
105512568  STAM2; signal transducing adapter molecule 2 [KO:K04705]
105527541  STAM; signal transducing adapter molecule 1 [KO:K04705]
105508589  TSG101; tumor susceptibility gene 101 protein [KO:K12183]
105504091  MVB12B; multivesicular body subunit 12B [KO:K12186]
105500320  multivesicular body subunit 12A-like [KO:K12186]
105500321  MVB12A; multivesicular body subunit 12A isoform X1 [KO:K12186]
105508969  VPS28; vacuolar protein sorting-associated protein 28 homolog isoform X1 [KO:K12184]
105516311  VPS37B; vacuolar protein sorting-associated protein 37B isoform X1 [KO:K12185]
105503540  VPS37D; vacuolar protein sorting-associated protein 37D [KO:K12185]
105512364  VPS37C; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 37C [KO:K12185]
105506663  VPS37A; vacuolar protein sorting-associated protein 37A isoform X1 [KO:K12185]
105524657  SNF8; vacuolar-sorting protein SNF8 [KO:K12188]
105501464  VPS36; vacuolar protein-sorting-associated protein 36 [KO:K12190]
105502988  VPS25; vacuolar protein-sorting-associated protein 25 [KO:K12189]
105505420  CHMP6; charged multivesicular body protein 6 [KO:K12195]
105524302  CHMP4B; charged multivesicular body protein 4b isoform X1 [KO:K12194]
105503724  CHMP4A; LOW QUALITY PROTEIN: charged multivesicular body protein 4a [KO:K12194]
105508275  CHMP4C; charged multivesicular body protein 4c [KO:K24782]
105527798  CHMP3; charged multivesicular body protein 3 isoform X1 [KO:K12193]
105524033  CHMP2A; charged multivesicular body protein 2a isoform X1 [KO:K12191]
105501590  CHMP2B; charged multivesicular body protein 2b isoform X1 [KO:K12192]
105510198  CHMP7; charged multivesicular body protein 7 [KO:K15053]
105504522  VPS4A; vacuolar protein sorting-associated protein 4A [KO:K12196]
105520027  VPS4B; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 4B [KO:K12196]
105526143  VTA1; vacuolar protein sorting-associated protein VTA1 homolog isoform X1 [KO:K12199]
105501922  CHMP1A; charged multivesicular body protein 1a [KO:K12197]
105507908  CHMP1B; charged multivesicular body protein 1b [KO:K12197]
105500863  CHMP5; charged multivesicular body protein 5 isoform X1 [KO:K12198]
105525969  IST1; IST1 homolog isoform X1 [KO:K19476]
105525799  PDCD6IP; programmed cell death 6-interacting protein isoform X1 [KO:K12200]
105510555  SPG21; maspardin [KO:K19367]
105506730  IGF2R; cation-independent mannose-6-phosphate receptor [KO:K06564]
105510567  SNX1; sorting nexin-1 isoform X1 [KO:K17917]
105527400  SNX2; sorting nexin-2 isoform X1 [KO:K17917]
105524269  SNX6; sorting nexin-6 [KO:K17920]
105512149  SNX32; sorting nexin-32 [KO:K17920]
105526777  SNX5; sorting nexin-5 isoform X1 [KO:K17920]
105502517  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
105503192  HRAS; GTPase HRas isoform X1 [KO:K02833]
105522527  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
105527810  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
105512612  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
105509706  RHOA; transforming protein RhoA isoform X1 [KO:K04513]
105505346  RHOC; rho-related GTP-binding protein RhoC isoform X1 [KO:K04513]
105513804  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105513823  mamu class I histocompatibility antigen, alpha chain F-like isoform X1 [KO:K06751]
105513934  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
105513935  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105513936  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
105513982  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E-like [KO:K06751]
105513984  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E [KO:K06751]
105513986  HLA class I histocompatibility antigen, B-67 alpha chain-like [KO:K06751]
105513995  LOW QUALITY PROTEIN: histocompatibility antigen-related [KO:K06751]
105522311  FOLR3; folate receptor gamma [KO:K13649]
105522312  folate receptor alpha [KO:K13649]
105522313  FOLR2; folate receptor beta isoform X1 [KO:K13649]
105508509  CAV1; caveolin-1 isoform X1 [KO:K06278]
105525600  CAV3; caveolin-3 [KO:K12959]
105525040  EHD3; EH domain-containing protein 3 [KO:K12476]
105525433  EHD4; EH domain-containing protein 4 [KO:K12477]
105505796  EEA1; early endosome antigen 1 [KO:K12478]
105505780  RAB5A; ras-related protein Rab-5A isoform X1 [KO:K07887]
105500563  RAB5B; ras-related protein Rab-5B [KO:K07888]
105503017  RAB5C; ras-related protein Rab-5C isoform X1 [KO:K07889]
105523673  RABEP1; rab GTPase-binding effector protein 1 [KO:K12480]
105517918  RBSN; rabenosyn-5 [KO:K12481]
105505495  RAB4A; ras-related protein Rab-4A isoform X1 [KO:K07879]
105501209  RUFY2; RUN and FYVE domain-containing protein 2 isoform X1 [KO:K12482]
105524776  RUFY1; RUN and FYVE domain-containing protein 1 [KO:K12482]
105512195  EHD1; EH domain-containing protein 1 isoform X1 [KO:K12483]
105508827  VPS45; vacuolar protein sorting-associated protein 45 isoform X1 [KO:K12479]
105517977  SNX4; sorting nexin-4 [KO:K17919]
105507934  RAB31; ras-related protein Rab-31 [KO:K07891]
105507952  RAB22A; ras-related protein Rab-22A [KO:K07891]
105517715  RAB10; ras-related protein Rab-10 [KO:K07903]
105519783  RAB8A; ras-related protein Rab-8A isoform X1 [KO:K07901]
105510536  RAB11A; ras-related protein Rab-11A isoform X1 [KO:K07904]
105507240  ras-related protein Rab-11A isoform X1 [KO:K07904]
105520923  RAB11B; ras-related protein Rab-11B [KO:K07905]
105501760  RAB11FIP2; rab11 family-interacting protein 2 isoform X1 [KO:K12484]
105525171  RAB11FIP1; rab11 family-interacting protein 1 [KO:K12484]
105514245  RAB11FIP5; rab11 family-interacting protein 5 [KO:K12484]
105518259  ZFYVE27; protrudin isoform X1 [KO:K19368]
105512588  KIF5C; kinesin heavy chain isoform 5C [KO:K10396]
105519579  KIF5B; LOW QUALITY PROTEIN: kinesin-1 heavy chain [KO:K10396]
105500501  KIF5A; kinesin heavy chain isoform 5A isoform X1 [KO:K10396]
105508763  RAB11FIP4; rab11 family-interacting protein 4 [KO:K12485]
105526426  rab11 family-interacting protein 3-like [KO:K12485]
105521843  PARD3; partitioning defective 3 homolog [KO:K04237]
105502368  partitioning defective 6 homolog beta [KO:K06093]
105502369  partitioning defective 6 homolog beta-like [KO:K06093]
105504536  PARD6A; partitioning defective 6 homolog alpha isoform X1 [KO:K06093]
105503943  PRKCZ; protein kinase C zeta type [KO:K18952] [EC:2.7.11.13]
105516724  PRKCI; protein kinase C iota type [KO:K06069] [EC:2.7.11.13]
105505977  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
105522505  SMAP1; stromal membrane-associated protein 1 isoform X1 [KO:K12486]
105521150  SMAP2; stromal membrane-associated protein 2 isoform X1 [KO:K12486]
105510856  GIT1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
105507653  GIT2; ARF GTPase-activating protein GIT2 isoform X1 [KO:K12487]
105509066  ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12488]
105525337  ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 [KO:K12488]
105514293  ASAP3; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [KO:K12488]
105522042  ACAP3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 [KO:K12489]
105523601  ACAP1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [KO:K12489]
105525523  ACAP2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 [KO:K12489]
105519625  ARAP1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K18439]
105516798  ARAP2; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 [KO:K18440]
105510111  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [KO:K12490]
105502924  AGAP1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 [KO:K12491]
105517741  LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5-like [KO:K12491]
105511331  AGAP3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12491]
105500488  AGAP2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K17848]
105506345  ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [KO:K12492]
105504919  ADP-ribosylation factor GTPase-activating protein 3-like isoform X1 [KO:K12493]
105527121  ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
105514032  ARFGAP3; ADP-ribosylation factor GTPase-activating protein 3 [KO:K12493]
105524288  PSD4; PH and SEC7 domain-containing protein 4 isoform X1 [KO:K12494]
105507000  PSD2; PH and SEC7 domain-containing protein 2 [KO:K12494]
105507104  PSD; PH and SEC7 domain-containing protein 1 [KO:K12494]
105514918  IQSEC2; IQ motif and SEC7 domain-containing protein 2 [KO:K12495]
105522585  IQSEC3; IQ motif and SEC7 domain-containing protein 3 [KO:K12495]
105517893  IQSEC1; IQ motif and SEC7 domain-containing protein 1 isoform X1 [KO:K12495]
105514887  CYTH2; cytohesin-2 [KO:K18441]
105506307  CYTH3; cytohesin-3 [KO:K18441]
105527806  CYTH4; cytohesin-4 isoform X1 [KO:K18441]
105521638  CYTH1; cytohesin-1 [KO:K18441]
105502584  ARFGEF2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 [KO:K18442]
105510907  ARFGEF1; brefeldin A-inhibited guanine nucleotide-exchange protein 1 [KO:K18442]
105507172  GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [KO:K18443]
105508930  ADP-ribosylation factor 2-like [KO:K07937]
105517247  ADP-ribosylation factor 1-like isoform X1 [KO:K07937]
105524997  ARF1; ADP-ribosylation factor 1 isoform X1 [KO:K07937]
105507601  ADP-ribosylation factor 1 isoform X1 [KO:K07937]
105507644  ARF3; ADP-ribosylation factor 3 isoform X1 [KO:K07938]
105515418  ARF4; ADP-ribosylation factor 4 isoform X1 [KO:K07939]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
cang04060  Cytokine-cytokine receptor interaction
cang04070  Phosphatidylinositol signaling system
cang04130  SNARE interactions in vesicular transport
cang04142  Lysosome
cang04350  TGF-beta signaling pathway
KO pathway
ko04144   
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