KEGG   PATHWAY: ehs00230
Entry
ehs00230                    Pathway                                
Name
Purine metabolism - Eurypyga helias (sunbittern)
Class
Metabolism; Nucleotide metabolism
Pathway map
ehs00230  Purine metabolism
ehs00230

Module
ehs_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ehs00230]
ehs_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ehs00230]
ehs_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ehs00230]
Other DBs
GO: 0006163 0042278
Organism
Eurypyga helias (sunbittern) [GN:ehs]
Gene
104504428  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104516721  NUDT5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104508549  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104504339  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104504798  ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
104516664  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104506534  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104505978  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104503435  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104515340  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104502724  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104517339  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104509008  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104509188  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
104503112  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
104516064  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104504936  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
104507574  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104509467  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104508960  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104515054  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104515154  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104508353  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104504858  nucleoside diphosphate kinase A-like [KO:K00940] [EC:2.7.4.6]
104502609  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
104516801  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
104512046  NME2; nucleoside diphosphate kinase B [KO:K00940] [EC:2.7.4.6]
104515607  LOW QUALITY PROTEIN: adenylate kinase 9-like [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104513978  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
104513993  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104514408  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104506091  ENTPD8; LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
104513918  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
104513227  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
104514504  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104502655  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104507011  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104510714  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104512780  LOW QUALITY PROTEIN: GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
104515796  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
104510119  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
104511070  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104507472  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104504346  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104504482  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104510986  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
104509139  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104512940  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104506918  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104509123  guanylate cyclase soluble subunit alpha-3-like isoform X1 [KO:K12318] [EC:4.6.1.2]
104513190  GUCY1B3; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
104508812  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104502570  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104513905  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
104509550  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
104517286  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
104514896  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
104504161  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104512890  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
104502934  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104511965  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
104508190  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104509141  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104512038  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
104509477  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104516357  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104513382  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
104504065  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104507434  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104502827  AMPD3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
104509093  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104507613  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104512915  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104507989  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
104513169  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104502652  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
104506469  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104504570  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
104513366  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
104507282  ENPP3; LOW QUALITY PROTEIN: ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104503535  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104507116  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
104510870  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
104507248  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
104503063  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
104513161  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104510794  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104506561  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ehs00030  Pentose phosphate pathway
ehs00220  Arginine biosynthesis
ehs00250  Alanine, aspartate and glutamate metabolism
ehs00260  Glycine, serine and threonine metabolism
ehs00340  Histidine metabolism
ehs00630  Glyoxylate and dicarboxylate metabolism
ehs00730  Thiamine metabolism
ehs00740  Riboflavin metabolism
ehs00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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