KEGG   PATHWAY: pvul00230
Entry
pvul00230                   Pathway                                
Name
Purine metabolism - Patella vulgata (common limpet)
Class
Metabolism; Nucleotide metabolism
Pathway map
pvul00230  Purine metabolism
pvul00230

Module
pvul_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pvul00230]
pvul_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pvul00230]
pvul_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pvul00230]
pvul_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pvul00230]
pvul_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pvul00230]
pvul_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pvul00230]
pvul_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pvul00230]
Other DBs
GO: 0006163 0042278
Organism
Patella vulgata (common limpet) [GN:pvul]
Gene
126817113  ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
126823619  ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
126811765  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
126828012  ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
126819500  phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
126822036  phosphopentomutase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
126830889  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
126830188  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
126826795  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
126830505  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
126830190  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
126811749  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
126820308  bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
126816484  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
126812295  5'(3')-deoxyribonucleotidase, cytosolic type isoform X1 [KO:K01081] [EC:3.1.3.5]
126814847  cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
126815482  cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
126816610  mannosylglucosyl-3-phosphoglycerate phosphatase [KO:K01081] [EC:3.1.3.5]
126809691  snake venom 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
126810401  snake venom 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
126811187  snake venom 5'-nucleotidase isoform X1 [KO:K19970] [EC:3.1.3.5]
126821065  purine nucleoside phosphorylase isoform X1 [KO:K03783] [EC:2.4.2.1]
126814835  purine nucleoside phosphorylase isoform X1 [KO:K03783] [EC:2.4.2.1]
126831727  hypoxanthine-guanine phosphoribosyltransferase isoform X1 [KO:K00760] [EC:2.4.2.8]
126828663  inosine-5'-monophosphate dehydrogenase 1a [KO:K00088] [EC:1.1.1.205]
126830070  nucleoside diphosphate kinase B [KO:K00940] [EC:2.7.4.6]
126819318  nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
126808946  nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
126810479  adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
126815603  ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
126816836  ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
126827768  U8 snoRNA-decapping enzyme isoform X1 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
126817673  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
126824506  uncharacterized protein LOC126824506 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126812430  xanthine dehydrogenase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126825658  xanthine dehydrogenase/oxidase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126814815  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
126816968  GMP reductase 2 [KO:K00364] [EC:1.7.1.7]
126828169  guanine deaminase [KO:K01487] [EC:3.5.4.3]
126831601  guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
126830025  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
126818636  ribonucleoside-diphosphate reductase small chain isoform X2 [KO:K10808] [EC:1.17.4.1]
126825051  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
126814639  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
126831524  adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
126816269  adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
126811878  adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
126831735  adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
126830910  adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
126829944  guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
126830060  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
126811621  retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
126815553  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
126809843  receptor-type guanylate cyclase Gyc76C [KO:K12323] [EC:4.6.1.2]
126821318  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
130013026  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
126815371  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
126815377  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
126827754  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
126824266  atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
126825312  retinal guanylyl cyclase 2-like [KO:K12324] [EC:4.6.1.2]
126825377  atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
126832718  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4 [KO:K13755] [EC:3.1.4.17]
126830839  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1 [KO:K18283] [EC:3.1.4.17]
126810409  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform X1 [KO:K19021] [EC:3.1.4.17]
126815159  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13763] [EC:3.1.4.35]
126829639  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
126826707  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
126818239  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
126810997  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X2 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
126822339  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
126820959  adenylosuccinate synthetase isoform X1 [KO:K01939] [EC:6.3.4.4]
126831459  AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
126819465  uncharacterized protein LOC126819465 isoform X1 [KO:K00856] [EC:2.7.1.20]
126812286  uncharacterized protein LOC126812286 isoform X1 [KO:K00856] [EC:2.7.1.20]
126813969  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
126816069  adenosine deaminase isoform X1 [KO:K01488] [EC:3.5.4.4]
126820894  adenosine deaminase AGSA isoform X1 [KO:K19572] [EC:3.5.4.4]
126825669  adenosine deaminase AGSA [KO:K19572] [EC:3.5.4.4]
126808952  adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
126821588  adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
126825031  adenylate kinase [KO:K00939] [EC:2.7.4.3]
126828891  adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
126819234  GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
126821609  cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
126819777  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
126818389  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
126811747  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
126826991  urease subunit alpha [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pvul00030  Pentose phosphate pathway
pvul00220  Arginine biosynthesis
pvul00250  Alanine, aspartate and glutamate metabolism
pvul00260  Glycine, serine and threonine metabolism
pvul00340  Histidine metabolism
pvul00630  Glyoxylate and dicarboxylate metabolism
pvul00730  Thiamine metabolism
pvul00740  Riboflavin metabolism
pvul00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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