KEGG   PATHWAY: phas04070
Entry
phas04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Phyllostomus hastatus (greater spear-nosed bat)
Class
Environmental Information Processing; Signal transduction
Pathway map
phas04070  Phosphatidylinositol signaling system
phas04070

Organism
Phyllostomus hastatus (greater spear-nosed bat) [GN:phas]
Gene
123804307  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
123804838  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
123805434  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
123805537  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
123805718  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
123806556  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
123806874  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
123807024  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
123807026  MTM1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
123807677  MTMR7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
123807993  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
123808002  CALM1; calmodulin-1 [KO:K02183]
123808036  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
123808166  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
123808540  ITPK1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
123808665  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
123808974  ITPKA; inositol-trisphosphate 3-kinase A isoform X1 [KO:K00911] [EC:2.7.1.127]
123809878  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
123809968  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
123810929  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
123811116  INPP4A; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
123811613  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
123811737  CALM2; calmodulin-2 [KO:K02183]
123812354  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
123812463  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
123812563  DGKA; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
123813058  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
123813070  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
123813643  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
123813708  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
123814552  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
123814742  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
123814755  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
123814793  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
123814917  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
123815695  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
123815921  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
123815944  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
123816649  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
123817058  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
123817060  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
123817314  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [KO:K05857] [EC:3.1.4.11]
123817558  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
123817739  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
123818156  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
123818850  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
123819722  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
123820594  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
123820952  IPMK; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
123820957  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
123821009  [KO:K02183]
123822170  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
123822728  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
123823025  CALM3; calmodulin-3 [KO:K02183]
123823184  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
123823233  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
123823296  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV isoform X1 [KO:K20278] [EC:3.1.3.36]
123823716  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
123824140  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
123824256  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
123824527  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
123825494  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
123825682  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
123825848  IMPA1; inositol monophosphatase 1 isoform X1 [KO:K01092] [EC:3.1.3.25]
123826380  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
123826411  IMPA2; inositol monophosphatase 2 isoform X1 [KO:K01092] [EC:3.1.3.25]
123826750  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
123827104  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
123827781  OCRL; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
123828126  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
123828226  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
123828291  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
123828723  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
123828777  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
123828814  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
123828885  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
123829008  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
123829335  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
123829755  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
123829981  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
123830117  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
123830469  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
123830505  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
123830565  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123830610  SACM1L; phosphatidylinositol-3-phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
123830663  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
123830681  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
123831216  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
123831226  CALML3; calmodulin-like protein 3 [KO:K02183]
123831240  [KO:K02183]
123831845  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
123831922  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123832039  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
123832298  [KO:K02649]
123832493  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
123832717  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
123833039  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
phas04020  Calcium signaling pathway
phas04144  Endocytosis
phas04151  PI3K-Akt signaling pathway
phas04510  Focal adhesion
KO pathway
ko04070   

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