KEGG   PATHWAY: spu00380
Entry
spu00380                    Pathway                                
Name
Tryptophan metabolism - Strongylocentrotus purpuratus (purple sea urchin)
Class
Metabolism; Amino acid metabolism
Pathway map
spu00380  Tryptophan metabolism
spu00380

Module
spu_M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:spu00380]
spu_M00912  NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:spu00380]
Other DBs
GO: 0006568 0009851
Organism
Strongylocentrotus purpuratus (purple sea urchin) [GN:spu]
Gene
593764  tryptophan 2,3-dioxygenase isoform X1 [KO:K00453] [EC:1.13.11.11]
589461  tryptophan 2,3-dioxygenase-like [KO:K00453] [EC:1.13.11.11]
115927664  tryptophan 2,3-dioxygenase-like [KO:K00453] [EC:1.13.11.11]
577419  indoleamine 2,3-dioxygenase 1 [KO:K00463] [EC:1.13.11.52]
754565  indoleamine 2,3-dioxygenase 2 [KO:K00463] [EC:1.13.11.52]
100893352  indoleamine 2,3-dioxygenase 2 [KO:K00463] [EC:1.13.11.52]
100893038  kynurenine formamidase [KO:K01432] [EC:3.5.1.9]
115929317  kynurenine formamidase-like [KO:K01432] [EC:3.5.1.9]
752252  kynurenine formamidase-like [KO:K01432] [EC:3.5.1.9]
592365  kynurenine 3-monooxygenase [KO:K00486] [EC:1.14.13.9]
754267  kynureninase [KO:K01556] [EC:3.7.1.3]
582154  3-hydroxyanthranilate 3,4-dioxygenase [KO:K00452] [EC:1.13.11.6]
115926101  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase-like isoform X1 [KO:K03392] [EC:4.1.1.45]
115926819  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase-like [KO:K03392] [EC:4.1.1.45]
583530  2-aminomuconic semialdehyde dehydrogenase [KO:K23234] [EC:1.2.1.32]
764393  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial [KO:K15791] [EC:1.2.4.-]
576084  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [KO:K00658] [EC:2.3.1.61]
577103  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
580832  glutaryl-CoA dehydrogenase, mitochondrial [KO:K00252] [EC:1.3.8.6]
115928713  glutaryl-CoA dehydrogenase, mitochondrial-like [KO:K00252] [EC:1.3.8.6]
585357  trifunctional enzyme subunit alpha, mitochondrial [KO:K07515] [EC:4.2.1.17 1.1.1.211]
588204  peroxisomal bifunctional enzyme isoform X1 [KO:K07514] [EC:4.2.1.17 1.1.1.35 5.3.3.8]
753669  peroxisomal bifunctional enzyme-like isoform X1 [KO:K07514] [EC:4.2.1.17 1.1.1.35 5.3.3.8]
575690  Echs1; enoyl CoA hydratase, short chain, 1, mitochondrial [KO:K07511] [EC:4.2.1.17]
582126  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [KO:K00022] [EC:1.1.1.35]
763037  acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
584928  acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
115927929  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
579089  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
115928354  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
593717  kynurenine--oxoglutarate transaminase 3 isoform X1 [KO:K00816] [EC:2.6.1.7 4.4.1.13 2.6.1.64]
115918127  kynurenine--oxoglutarate transaminase 3-like isoform X1 [KO:K00816] [EC:2.6.1.7 4.4.1.13 2.6.1.64]
592969  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [KO:K00825] [EC:2.6.1.7 2.6.1.39]
100891652  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [KO:K00825] [EC:2.6.1.7 2.6.1.39]
105444816  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial-like [KO:K00825] [EC:2.6.1.7 2.6.1.39]
579472  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1 [KO:K00825] [EC:2.6.1.7 2.6.1.39]
578903  tryptophan 5-hydroxylase 1 isoform X1 [KO:K00502] [EC:1.14.16.4]
115922565  LOW QUALITY PROTEIN: tryptophan 5-hydroxylase 1-like [KO:K00502] [EC:1.14.16.4]
593847  LOW QUALITY PROTEIN: aromatic-L-amino-acid decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
577767  LOW QUALITY PROTEIN: aromatic-L-amino-acid decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
757080  aromatic-L-amino-acid decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
581752  aromatic-L-amino-acid decarboxylase-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
590013  amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
115918590  probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
583484  probable flavin-containing monoamine oxidase A isoform X1 [KO:K00274] [EC:1.4.3.4]
590198  probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
100891493  amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
105443950  amine oxidase [flavin-containing] B-like [KO:K00274] [EC:1.4.3.4]
581754  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
581706  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
105445554  aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
593236  aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
105445170  aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
756945  aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
588376  alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
580956  4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
583864  4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
115918585  4-trimethylaminobutyraldehyde dehydrogenase-like [KO:K00149] [EC:1.2.1.47 1.2.1.3]
100892264  uncharacterized protein LOC100892264 [KO:K01426] [EC:3.5.1.4]
578788  uncharacterized protein LOC578788 [KO:K01426] [EC:3.5.1.4]
100890319  uncharacterized protein LOC100890319 [KO:K01426] [EC:3.5.1.4]
576789  uncharacterized protein LOC576789 [KO:K01426] [EC:3.5.1.4]
115918304  uncharacterized protein LOC115918304 [KO:K01426] [EC:3.5.1.4]
576856  uncharacterized protein LOC576856 [KO:K01426] [EC:3.5.1.4]
105443268  uncharacterized protein LOC105443268 [KO:K01426] [EC:3.5.1.4]
100889766  uncharacterized protein LOC100889766 [KO:K01426] [EC:3.5.1.4]
578947  uncharacterized protein LOC578947 [KO:K01426] [EC:3.5.1.4]
588819  uncharacterized protein LOC588819 [KO:K01426] [EC:3.5.1.4]
577145  uncharacterized protein LOC577145 isoform X1 [KO:K01426] [EC:3.5.1.4]
548621  catalase [KO:K03781] [EC:1.11.1.6]
100888042  catalase-like [KO:K03781] [EC:1.11.1.6]
Compound
C00024  Acetyl-CoA
C00078  L-Tryptophan
C00108  Anthranilate
C00322  2-Oxoadipate
C00328  L-Kynurenine
C00331  Indolepyruvate
C00332  Acetoacetyl-CoA
C00398  Tryptamine
C00463  Indole
C00527  Glutaryl-CoA
C00632  3-Hydroxyanthranilate
C00637  Indole-3-acetaldehyde
C00643  5-Hydroxy-L-tryptophan
C00780  Serotonin
C00877  Crotonoyl-CoA
C00954  Indole-3-acetate
C00955  Indole-3-ethanol
C00978  N-Acetylserotonin
C01111  7,8-Dihydroxykynurenate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01249  7,8-Dihydro-7,8-dihydroxykynurenate
C01252  4-(2-Aminophenyl)-2,4-dioxobutanoate
C01598  Melatonin
C01717  4-Hydroxy-2-quinolinecarboxylic acid
C01987  2-Aminophenol
C02161  2-Aminophenoxazin-3-one
C02172  N-Acetylisatin
C02220  2-Aminomuconate
C02298  N-Acetylindoxyl
C02470  Xanthurenic acid
C02693  (Indol-3-yl)acetamide
C02700  L-Formylkynurenine
C02775  2,3-Dihydroxyindole
C02937  Indole-3-acetaldehyde oxime
C02938  3-Indoleacetonitrile
C03227  3-Hydroxy-L-kynurenine
C03230  (Indol-3-yl)glycolaldehyde
C03453  gamma-Oxalocrotonate
C03574  2-Formylaminobenzaldehyde
C03722  Quinolinate
C03824  2-Aminomuconate semialdehyde
C04409  2-Amino-3-carboxymuconate semialdehyde
C05634  5-Hydroxyindoleacetaldehyde
C05635  5-Hydroxyindoleacetate
C05636  3-Hydroxykynurenamine
C05637  4,8-Dihydroxyquinoline
C05638  5-Hydroxykynurenamine
C05639  4,6-Dihydroxyquinoline
C05640  Cinnavalininate
C05641  5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate
C05642  Formyl-N-acetyl-5-methoxykynurenamine
C05643  6-Hydroxymelatonin
C05644  3-Methylindolepyruvate
C05645  4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
C05646  5-Hydroxyindolepyruvate
C05647  Formyl-5-hydroxykynurenamine
C05648  5-Hydroxy-N-formylkynurenine
C05651  5-Hydroxykynurenine
C05652  4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate
C05653  Formylanthranilate
C05654  5-(2'-Formylethyl)-4,6-dihydroxypicolinate
C05655  5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
C05656  5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
C05658  Indoxyl
C05659  5-Methoxytryptamine
C05660  5-Methoxyindoleacetate
C05663  6-Hydroxykynurenate
C05830  8-Methoxykynurenate
C05831  3-Methoxyanthranilate
C05832  5-Hydroxyindoleacetylglycine
C05834  3-Methyldioxyindole
C05835  2-Formaminobenzoylacetate
C05837  Glucobrassicin
C06212  N-Methylserotonin
C06213  N-Methyltryptamine
C08313  Skatole
C10164  Picolinic acid
C16516  Indolylmethylthiohydroximate
C16517  Indolylmethyl-desulfoglucosinolate
C16518  S-(Indolylmethylthiohydroximoyl)-L-cysteine
C17203  N-Hydroxyl-tryptamine
C22006  (R)-(Indol-3-yl)lactate
C22202  2-Oxoindole-3-acetate
Reference
PMID:15749753
  Authors
Woodward AW, Bartel B
  Title
Auxin: regulation, action, and interaction.
  Journal
Ann Bot 95:707-35 (2005)
DOI:10.1093/aob/mci083
Related
pathway
spu00010  Glycolysis / Gluconeogenesis
spu00400  Phenylalanine, tyrosine and tryptophan biosynthesis
spu00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00380   
LinkDB

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