KEGG   PATHWAY: breg00230
Entry
breg00230                   Pathway                                
Name
Purine metabolism - Balearica regulorum gibbericeps (East African grey crowned-crane)
Class
Metabolism; Nucleotide metabolism
Pathway map
breg00230  Purine metabolism
breg00230

Module
breg_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:breg00230]
breg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:breg00230]
breg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:breg00230]
breg_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:breg00230]
breg_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:breg00230]
Other DBs
GO: 0006163 0042278
Organism
Balearica regulorum gibbericeps (East African grey crowned-crane) [GN:breg]
Gene
104629119  [KO:K01490] [EC:3.5.4.6]
104629287  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
104629446  [KO:K00940] [EC:2.7.4.6]
104629474  [KO:K00940] [EC:2.7.4.6]
104629540  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
104629697  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104629714  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104629742  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104630023  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104630054  GUCY1B3; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
104630183  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104630379  [KO:K12324] [EC:4.6.1.2]
104630405  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104630429  ENTPD5; LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104630565  PGM1; phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
104630742  [KO:K00940] [EC:2.7.4.6]
104630743  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
104630788  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104630821  GUCY1A3; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
104630957  [KO:K00940] [EC:2.7.4.6]
104631037  [KO:K12319] [EC:4.6.1.2]
104631057  [KO:K00948] [EC:2.7.6.1]
104631928  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
104632215  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
104632334  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104632377  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104632827  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
104632835  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104632898  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104633046  AK2; adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
104633093  [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104633382  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104633397  ATIC; LOW QUALITY PROTEIN: bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104633735  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104633761  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104633803  [KO:K13755] [EC:3.1.4.17]
104634072  NT5E; LOW QUALITY PROTEIN: 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104634429  [KO:K10808] [EC:1.17.4.1]
104634519  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
104634551  [KO:K01510] [EC:3.6.1.5]
104634553  [KO:K01510] [EC:3.6.1.5]
104635013  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
104635480  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104635522  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
104635625  [KO:K12318] [EC:4.6.1.2]
104635665  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
104635698  [KO:K00939] [EC:2.7.4.3]
104635839  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104635920  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104635952  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
104636056  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
104636096  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104636422  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
104636451  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104636476  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104636567  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104636610  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
104636690  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
104637201  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104637525  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104637700  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
104637747  [KO:K13293] [EC:3.1.4.53]
104637966  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104638044  NUDT5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104638310  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104638616  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
104638748  [KO:K01509] [EC:3.6.1.-]
104638776  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104638973  [KO:K01081] [EC:3.1.3.5]
104639144  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
104639241  GMPR; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
104639445  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104639477  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104639786  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104639867  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104639909  [KO:K01939] [EC:6.3.4.4]
104640205  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
104640477  [KO:K13293] [EC:3.1.4.53]
104640541  [KO:K01081] [EC:3.1.3.5]
104640632  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104640852  ADCY3; LOW QUALITY PROTEIN: adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
104640922  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
104640931  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104641081  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104641187  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104641189  [KO:K12324] [EC:4.6.1.2]
104641433  [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104641494  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104641570  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104641727  [KO:K00365] [EC:1.7.3.3]
104641861  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 [KO:K18437] [EC:3.1.4.53]
104641889  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
104641936  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
104642000  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104642651  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104643151  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104643197  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104643234  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104643302  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104643784  [KO:K19021] [EC:3.1.4.17]
104643838  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104643883  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
breg00030  Pentose phosphate pathway
breg00220  Arginine biosynthesis
breg00250  Alanine, aspartate and glutamate metabolism
breg00260  Glycine, serine and threonine metabolism
breg00340  Histidine metabolism
breg00630  Glyoxylate and dicarboxylate metabolism
breg00730  Thiamine metabolism
breg00740  Riboflavin metabolism
breg00790  Folate biosynthesis
KO pathway
ko00230   

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