KEGG   PATHWAY: iti04070
Entry
iti04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Class
Environmental Information Processing; Signal transduction
Pathway map
iti04070  Phosphatidylinositol signaling system
iti04070

Organism
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) [GN:iti]
Gene
101954421  Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
101954534  Pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
101954942  Mtmr8; myotubularin-related protein 8 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101954994  Prkcb; protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
101954996  Inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
101955103  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
101956085  Inpp4b; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
101956182  Plcz1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
101956466  Pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
101956902  Dgkk; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
101957054  Pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
101957148  Plcd3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2 [KO:K05857] [EC:3.1.4.11]
101957392  Pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
101957620  Ip6k2; inositol hexakisphosphate kinase 2 isoform X2 [KO:K07756] [EC:2.7.4.21]
101957898  Cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
101958075  Cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
101958207  Dgkz; diacylglycerol kinase zeta isoform X3 [KO:K00901] [EC:2.7.1.107]
101958232  Plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
101958559  Synj2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
101958809  Ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
101959539  Pip5k1a; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
101959595  Pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
101959636  Mtmr7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101959948  Mtmr2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101960054  Inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
101960394  Pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
101960396  Pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
101960788  Plcd4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X5 [KO:K05857] [EC:3.1.4.11]
101961077  Plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
101961891  Pip4p1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
101962301  Itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
101962360  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
101962649  Mtmr4; myotubularin-related protein 4 isoform X3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101962660  [KO:K00922] [EC:2.7.1.153]
101962752  Synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
101962775  Itpr1; inositol 1,4,5-trisphosphate receptor type 1 isoform X9 [KO:K04958]
101962793  Inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
101963168  Impa2; inositol monophosphatase 2 isoform X2 [KO:K01092] [EC:3.1.3.25]
101963261  Mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
101963324  Ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X3 [KO:K13024] [EC:2.7.4.24]
101964638  Prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
101964684  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
101964780  Itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
101964836  Bpnt2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
101965034  Pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
101965148  Itpkb; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
101965304  Dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
101965906  [KO:K00922] [EC:2.7.1.153]
101965956  Pi4k2a; phosphatidylinositol 4-kinase type 2-alpha isoform X1 [KO:K13711] [EC:2.7.1.67]
101967023  [KO:K20278] [EC:3.1.3.36]
101967074  Calm1; calmodulin-1 [KO:K02183]
101967140  Itpk1; inositol-tetrakisphosphate 1-kinase isoform X2 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
101967142  Cds1; phosphatidate cytidylyltransferase 1 isoform X1 [KO:K00981] [EC:2.7.7.41]
101967144  Inpp4a; inositol polyphosphate-4-phosphatase type I A isoform X7 [KO:K01109] [EC:3.1.3.66]
101967532  Pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
101967618  Mtmr1; myotubularin-related protein 1 isoform X11 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101967750  Inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2 [KO:K15909] [EC:3.1.3.86]
101968088  Mtm1; myotubularin isoform X3 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
101968490  Dgkq; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
101968564  Itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
101968896  [KO:K00922] [EC:2.7.1.153]
101969131  Pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X4 [KO:K00889] [EC:2.7.1.68]
101969505  Ipmk; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
101969656  Inpp5a; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
101969927  Ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
101970353  Ip6k1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
101970466  Prkca; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
101970750  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
101970867  Sacm1l; phosphatidylinositol-3-phosphatase SAC1 isoform X1 [KO:K21797] [EC:3.1.3.-]
101971351  Pi4ka; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
101971550  Plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2 [KO:K05857] [EC:3.1.4.11]
101972101  Pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
101972436  Calml6; calmodulin-like protein 6 [KO:K02183]
101972472  Calm2; calmodulin-2 [KO:K02183]
101972808  Mtmr6; myotubularin-related protein 6 isoform X2 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101972903  Pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
101973066  Dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
101973111  Plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
101973567  Pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
101973994  Pip5k1b; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
101974167  Ippk; inositol-pentakisphosphate 2-kinase isoform X2 [KO:K10572] [EC:2.7.1.158]
101974679  Dgkg; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
101974987  Ip6k3; inositol hexakisphosphate kinase 3 isoform X2 [KO:K07756] [EC:2.7.4.21]
101975217  [KO:K02183]
101975242  Dgki; diacylglycerol kinase iota isoform X6 [KO:K00901] [EC:2.7.1.107]
101975260  Calml4; calmodulin-like protein 4 isoform X1 [KO:K02183]
101975316  Dgkd; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
101975344  Plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X4 [KO:K05860] [EC:3.1.4.11]
101975534  Impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
101975553  Itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X2 [KO:K04960]
101976353  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
101976513  [KO:K02183]
101976794  Calml5; calmodulin-like protein 5 [KO:K02183]
101976904  Inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
101976937  Dgka; diacylglycerol kinase alpha isoform X3 [KO:K00901] [EC:2.7.1.107]
101977547  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
101978138  Calm3; calmodulin-3 isoform X2 [KO:K02183]
101978230  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
101978560  Plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [KO:K05858] [EC:3.1.4.11]
110597716  Inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
iti04020  Calcium signaling pathway
iti04144  Endocytosis
iti04151  PI3K-Akt signaling pathway
iti04510  Focal adhesion
KO pathway
ko04070   

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