KEGG ORTHOLOGY: K06254

ORTHOLOGY: K06254

Entry

K06254                      KO

Symbol

AGRN

Name

agrin

Pathway

map04512

ECM-receptor interaction

map04820

Cytoskeleton in muscle cells

Disease

H00770

Congenital myasthenic syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06254  AGRN; agrin
09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    K06254  AGRN; agrin
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans
    K06254  AGRN; agrin
Proteoglycans [BR:ko00535]
Extracellular matrix (ECM) proteoglycans
  Basement membrane proteoglycans
   K06254  AGRN; agrin

Genes

HSA:	375790(AGRN)

PTR:	100609326(AGRN)

PPS:	100990648(AGRN)

GGO:	129532440(AGRN)

PON:	100460940(AGRN)

PPYG:

129011158(AGRN)

NLE:	100590158(AGRN)

HMH:	116812760(AGRN)

SSYN:

129472073(AGRN)

MCC:	700400(AGRN)

MCF:	102117424(AGRN)

MTHB:

126951513

MNI:	105498298(AGRN)

CSAB:

103225827(AGRN)

CATY:

105572444(AGRN)

PANU:

101024235(AGRN)

TGE:	112625122(AGRN)

MLEU:

105555186(AGRN)

RRO:	104673225(AGRN)

RBB:	108516787(AGRN)

TFN:	117093488(AGRN)

PTEH:

111526851(AGRN)

CANG:

105522037(AGRN)

CJC:	100385349(AGRN)

SBQ:	101037114(AGRN)

CIMI:

108313910(AGRN)

ANAN:

105727803(AGRN)

CSYR:

103252923(AGRN)

MMUR:

105877632(AGRN)

LCAT:

123636038(AGRN)

PCOQ:

105820950(AGRN)

OGA:	100957332(AGRN)

MMU:	11603(Agrn)

MCAL:

110292528(Agrn)

MPAH:

110323907(Agrn)

RNO:	25592(Agrn)

MCOC:

116097176(Agrn)

ANU:	117708550(Agrn)

ASYL:

127681807(Agrn)

MUN:	110560333(Agrn)

CGE:	100765949(Agrn)

MAUA:

101831248(Agrn)

PROB:

127213481(Agrn)

PLEU:

114708267(Agrn)

MORG:

121443541 121448070

MFOT:

126493199

AAMP:

119817019(Agrn)

NGI:	103749726(Agrn)

HGL:	101724623(Agrn)

CPOC:

100716304(Agrn)

CCAN:

109685580(Agrn)

DORD:

105984053(Agrn)

DSP:	122127352(Agrn)

DMER:

138838043(Agrn)

PLOP:

125354445(Agrn)

NCAR:

124975952

MMMA:

107155605(Agrn)

ITI:	101956812(Agrn)

OCU:

103347121

OPI:

101527442

TUP:	102496812(AGRN)

GVR:	103588093(AGRN)

CFA:	479574(AGRN)

VVP:	112926137(AGRN)

VLG:	121499979(AGRN)

NPO:	129497188(AGRN)

AML:	100470903(AGRN)

UMR:	103682088(AGRN)

UAH:	113270653(AGRN)

UAR:	123792749(AGRN)

ELK:

111154720

LLV:

125097169

MPUF:

101686006(AGRN)

MNP:	132001374(AGRN)

MLK:	131810345(AGRN)

NVS:	122899318(AGRN)

ORO:	101374616(AGRN)

EJU:	114213350(AGRN)

ZCA:	113937898(AGRN)

MLX:	118020137(AGRN)

NSU:	110575093(AGRN)

LWW:	102736962(AGRN)

FCA:	101101121(AGRN)

PYU:	121018820(AGRN)

PCOO:

112848660(AGRN)

PBG:	122479765(AGRN)

PVIV:

125172380(AGRN)

LRUF:

124515757

LGF:	123596985(AGRN)

AJU:

106988748

PTG:	102953849(AGRN)

PPAD:

109273904(AGRN)

PUC:

125913252

PLEZ:

122227045(AGRN)

HHV:	120242559(AGRN)

BTA:	525795(AGRN)

BOM:	102266131(AGRN)

BIU:	109570417(AGRN)

BBUB:

102402519(AGRN)

BBIS:

104996106(AGRN)

CHX:	102169403(AGRN)

OAS:	101107299(AGRN)

BTAX:

128061392(AGRN)

CSUM:

138090718(AGRN)

ODA:	120880605(AGRN)

CCAD:

122451970(AGRN)

MREE:

136168484(AGRN)

OVR:	110124974(AGRN)

MBEZ:

129551398(AGRN)

SSC:	100621139(AGRN)

CFR:	102506186(AGRN)

CBAI:

105071343(AGRN)

CDK:	105105588(AGRN)

VPC:	102538783(AGRN)

BACU:

103008770(AGRN)

BMUS:

118904417(AGRN)

LVE:	103076872(AGRN)

OOR:	101275438(AGRN)

LALB:

132515357(AGRN)

GMF:	115866652(AGRN)

DDP:	132425945(AGRN)

DLE:	111187096(AGRN)

PCAD:

102987218(AGRN)

PSIU:

116761348(AGRN)

PPHC:

136119581(AGRN)

NASI:

112409895(AGRN)

ECB:	100066334(AGRN)

EPZ:	103558565(AGRN)

EAI:	106845249(AGRN)

MMYO:

118655558(AGRN)

MDT:	132231813(AGRN)

MYUM:

139002747(AGRN)

PKL:	118718066(AGRN)

EFUS:

103295349(AGRN)

MNA:

107544132

DRO:	112299598(AGRN)

SHON:

118998230(AGRN)

AJM:	119050520(AGRN)

PDIC:

114497220(AGRN)

PHAS:

123831607(AGRN)

MMF:	118643420(AGRN)

PPAM:

129078709(AGRN)

HAI:	109391179(AGRN)

RFQ:	117026787(AGRN)

PALE:

102886946(AGRN)

PGIG:

120614074(AGRN)

PVP:	105309829(AGRN)

RAY:	107510721(AGRN)

MJV:	108405693(AGRN)

TOD:	119235445(AGRN)

SARA:

101549454(AGRN)

SFUM:

130036505(AGRN)

SETR:

126010907(AGRN)

LAV:	100661357(AGRN)

TMU:

101343627

ETF:	101642672(AGRN)

DNM:	101411517(AGRN)

MDO:	100619189(AGRN)

GAS:	123240916(AGRN)

SHR:	100915940(AGRN)

AFZ:

127556036

PCW:	110201201(AGRN)

TVP:	118837780(AGRN)

PBRV:

138154597(AGRN)

MLAO:

141509331(AGRN)

OAA:	100089926(AGRN)

TACU:

119928248(AGRN)

GGA:	396538(AGRN)

PCOC:

116242594(AGRN)

MGP:	100543025(AGRN)

CJO:	107323511(AGRN)

TPAI:

128084874(AGRN)

LMUT:

125703264(AGRN)

NMEL:

110408569(AGRN)

APLA:

101799524(AGRN)

ACYG:

106044274(AGRN)

CATA:

118253311(AGRN)

AFUL:

116497638(AGRN)

TGU:	100219336(AGRN)

LSR:	110474415(AGRN)

PMOA:

120511020(AGRN)

OTC:	121344139(AGRN)

PRUF:

121356383 121358337

ATRC:

139600841(AGRN)

OMA:	130261847(AGRN)

PHI:	102109265(AGRN)

CCAE:

111938484(AGRN)

CCW:	104693404(AGRN)

CBRC:

103622295(AGRN)

ACOE:

138121336(AGRN)

ETL:

114071021

ZLE:	135456711(AGRN)

ACHL:

103811278(AGRN)

HRT:	120762248(AGRN)

CCIC:

134052797(AGRN)

FPG:	101919034(AGRN)

FCH:	102047683(AGRN)

CCRI:

104161322(AGRN)

NNT:	104402795(AGRN)

SHAB:

115617376(AGRN)

ACUN:

113487803(AGRN)

TALA:

104360213(AGRN)

ACHC:

115342933(AGRN)

HLE:	104837926(AGRN)

AGEN:

126041473

HHAR:

128144174(AGRN)

GCL:

127024736

LDI:	104352739(AGRN)

DPUB:

104305935(AGRN)

PPUS:

135190596(AGRN)

BRHI:

104493019(AGRN)

EGZ:	104133391(AGRN)

NNI:	104008971(AGRN)

PCAO:

104053186(AGRN)

PADL:

103917958(AGRN)

AFOR:

103894742(AGRN)

FGA:	104079910(AGRN)

CBOY:

140661519(AGRN)

CLV:	102096284(AGRN)

CNIC:

135997442(AGRN)

MUI:

104542880

PGUU:

104468750(AGRN)

PLET:

104622434(AGRN)

CUCA:

104055583(AGRN)

TEO:

104374244

BREG:

104642303(AGRN)

OHA:	104336065(AGRN)

ACAR:

104521195(AGRN)

CPEA:

104395554(AGRN)

CVF:	104290547(AGRN)

RTD:	128918381(AGRN)

CRID:

134523987(AGRN)

AAM:	106495570(AGRN)

AROW:

112970062(AGRN)

NPD:	112957438(AGRN)

TGT:	104569278(AGRN)

DNE:	112983504(AGRN)

SCAM:

104141995(AGRN)

ASN:	102372455(AGRN)

AMJ:	102562839(AGRN)

CPOO:

109314435(AGRN)

GGN:	109293722(AGRN)

CMY:	102935043(AGRN)

CCAY:

125624270(AGRN)

DCC:	119845130(AGRN)

CPIC:

101941018(AGRN)

TST:	117867790(AGRN)

CABI:

116824593(AGRN)

MRV:	120387826(AGRN)

ACS:

100560607

ASAO:

132765012(AGRN)

PVT:	110073261(AGRN)

SUND:

121936715(AGRN)

PMUR:

107298562(AGRN)

CTIG:

120319241(AGRN)

PGUT:

117658754(AGRN)

PCAE:

139326167(AGRN)

APRI:

131186919(AGRN)

PTEX:

113446223(AGRN)

NSS:	113421268(AGRN)

VKO:	123031022(AGRN)

PMUA:

114602499(AGRN)

PRAF:

128419746(AGRN)

ZVI:	118086430(AGRN)

HCG:	128338425(AGRN)

GJA:	107110832(AGRN)

STOW:

125445483(AGRN)

EMC:	129344551(AGRN)

XLA:	108696525 108697619

XTR:	100492176(agrn)

NPR:	108792691(AGRN)

RTEM:

120915451(AGRN)

ACAT:

141111072(AGRN)

BBUF:

120997099(AGRN)

BGAR:

122928691(AGRN)

DTC:	141097854(AGRN)

PWL:	138301064(AGRN)

MUO:	115456860(AGRN)

GSH:	117348907(AGRN)

DRE:	565373(agrN)

SRX:	107716114 107737670

SANH:

107673061 107687421(agrn)

SGH:	107591095 107593945

CCAR:

109045062 109045073

CAUA:

113045587 113068901

CGIB:

127944967 128011464

PTET:

122328495(agrn)

LROH:

127155121(agrn)

GRF:

141290563

OMC:	131532420(agrn)

PPRM:

120463826(agrn)

RKG:	130102174(agrn)

MAMB:

125260401(agrn)

CIDE:

127504458

CERY:

137009753(agrn)

MASI:

127418985 127419689

TROS:

130545424(agrn)

TDW:	130409657(agrn)

MANU:

129430917(agrn)

PDAB:

135775548(agrn)

IPU:

108276013

IFU:	128619476(agrn)

PHYP:

113530416(agrn)

TFD:	113658124(agrn)

TVC:	132862512(agrn)

CGAR:

128510783(agrn)

NGRA:

132897026(agrn)

TRN:	134333684(agrn)

AMEX:

103033713(agrn)

CMAO:

118821955(agrn)

EEE:	113580177(agrn)

CHAR:

105898943(agrn)

SPIL:

134088111(agrn)

TRU:	101076403(agrn)

TFS:	130529464(agrn)

LCO:	104919514(agrn)

TBEN:

117494104(agrn)

CGOB:

115010602(agrn)

PGEO:

117450117(agrn)

GACU:

117532844(agrn)

EMAC:

134865887(agrn)

ELY:	117258237(agrn)

EFO:	125891638(agrn)

PLEP:

121946576(agrn)

SLUC:

116040744(agrn)

ECRA:

117948200(agrn)

ESP:	116692595(agrn)

PFLV:

114558259(agrn)

GAT:	120828744(agrn)

PPUG:

119222317(agrn)

AFB:	129099375(agrn)

CLUM:

117734185(agrn)

PSWI:

130198902(agrn)

CANA:

137800484(agrn)

CVE:

137887188

MSAM:

119905925(agrn)

SCHU:

122882489(agrn)

CUD:	121517157(agrn)

SPUL:

138589182(agrn)

LMIX:

132990336(agrn)

ALAT:

119022782(agrn)

ASTR:

137605909(agrn)

MZE:	101470011(agrn)

ONL:	109196113(agrn)

OAU:	116317380(agrn)

OLA:	101156494(agrn)

OML:	112159698(agrn)

XMA:	102223587(agrn)

XCO:	114147877(agrn)

XHE:	116719886(agrn)

PRET:

103467113(agrn)

PFOR:

103153506(agrn)

GAF:	122838021(agrn)

PPRL:

129354787(agrn)

CVG:	107086710(agrn)

CTUL:

119786485(agrn)

GMU:	124873067(agrn)

NFU:	107391284(agrn)

KMR:	108233080(agrn)

ALIM:

106518901(agrn)

NWH:

119417727

AOCE:

111567357(agrn)

EJA:	138193107(agrn)

BFRE:

138618318(agrn)

MCEP:

125016914(agrN)

CSEM:

103384898(agrn)

POV:	109630798(agrn)

SSEN:

122776607(agrn)

SSOE:

131469114(agrn)

HHIP:

117765277(agrn)

HSP:	118110735(agrn)

PPLT:

128441917(agrn)

SMAU:

118316568(agrn)

LCF:

108882626

SDU:	111227618(agrn)

SLAL:

111656116(agrn)

XGL:	120803756(agrn)

HCQ:	109511715(agrn)

SSCV:

125988839(agrn)

SBIA:

133490428(agrn)

PEE:	133399880(agrn)

PTAO:

133475014(agrn)

BPEC:

110158079(agrn)

ENY:	140363198(agrn)

MALB:

109967151(agrn)

BSPL:

114858643(agrn)

SJO:	128357525(agrn)

SSCO:

133987419(agrn)

SASA:

106566949 106572186

STRU:

115166082 115168970

OTW:	112221492 112233024

OMY:	110491868 110532178(agrn)

OGO:	124031853 124046196

ONE:	115101912 115132061(agrn)

OKI:	109869661 109907909

OKE:	118360235 118360591

OMM:	135504500 135527407

OCLA:

139368345 139416419

SALP:

111966913 111976655

SNH:	120059395 120060868

CCLU:

121538244 121545981

ELS:	105013931(agrn)

OEP:

SFM:

PKI:

AANG:

AROT:

CCOG:

LOC:	102697587(agrn)

PSPA:

121328241 121328906

ARUT:

117425132 117431977(agrn)

PSEX:

120530866(agrn)

CMK:	103187444(agrn)

RTP:	109931424(agrn)

CPLA:

122540408(agrn)

HOC:	132833782(agrn)

LERI:

129711715(agrn)

HAKA:

140718476(agrn)

PMRN:

116946850 116950497

LRJ:	133351170 133352504

BFO:

BBEL:

CIN:

SCLV:

AFIL:

PFLL:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

CCOA:

PBAR:

VEM:

COBS:

TLN:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

TPRE:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

CINS:

CCIN:

TCA:

TMOL:

ESIM:

EFOR:

SOY:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_203716

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

DCI:

HHAL:

NLU:

HVI:	124361818 124362396

PHU:	Phum_PHUM498630

FOC:

TPAL:

ZNE:

CSEC:

PAME:

BROR:

IEL:

HAMR:

DMK:

AFRA:

PJA:	122248847 122255806

PCHN:

125041171

HAME:

121861435 121868725 121874460

PCLA:

123764756 123770855 138351041

PTRU:

MNZ:

MRJ:

PORN:

HAZT:

LSM:	121115029 121118947

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

GOE:

DPTE:

DFR:

CSCU:

CVS:	136985828 136985829

PTEP:

107441737

ABRU:

129959235 129961816 129961847 129961970

UDV:	129225012 129225013 129225314

SDM:	118193606 118203430

CEL:	CELE_F41G3.12(agr-1)

CBR:	CBG_11147(Cbr-agr-1)

CRQ:	GCK72_006345

PVUL:

LSAX:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

AIRR:

MMER:

MAEA:

OSN:

LJP:

SMM:	Smp_155050

LLON:

135496773

XEN:	124444502 124452913

TAD:	TRIADDRAFT_57635

» show all

Reference

PMID:9652404

Authors

Groffen AJ, Buskens CA, van Kuppevelt TH, Veerkamp JH, Monnens LA, van den Heuvel LP

Title

Primary structure and high expression of human agrin in basement membranes of adult lung and kidney.

Journal

Eur J Biochem 254:123-8 (1998)
DOI:10.1046/j.1432-1327.1998.2540123.x

Sequence

[hsa:375790]

Reference

PMID:12671652

Authors

Bezakova G, Ruegg MA

Title

New insights into the roles of agrin.

Journal

Nat Rev Mol Cell Biol 4:295-308 (2003)
DOI:10.1038/nrm1074

LinkDB

DBGET integrated database retrieval system