KEGG   PATHWAY: ncc00230
Entry
ncc00230                    Pathway                                
Name
Purine metabolism - Notothenia coriiceps (black rockcod)
Class
Metabolism; Nucleotide metabolism
Pathway map
ncc00230  Purine metabolism
ncc00230

Module
ncc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ncc00230]
ncc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ncc00230]
ncc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ncc00230]
ncc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ncc00230]
Other DBs
GO: 0006163 0042278
Organism
Notothenia coriiceps (black rockcod) [GN:ncc]
Gene
104942730  nudt9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104963227  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
104955336  nudt5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104962117  pgm1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104948953  phosphoglucomutase-1-like [KO:K01835] [EC:5.4.2.2]
104951398  pgm2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104958987  prps1; ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
104947322  ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
104947088  ppat; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104959170  pfas; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
104947087  paics; multifunctional protein ADE2 isoform X1 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104967844  adsl; LOW QUALITY PROTEIN: adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104967071  atic; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104964011  aprt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104967381  metal transporter CNNM2-like [KO:K01081] [EC:3.1.3.5]
104967120  nt5c2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104946496  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104957953  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104963681  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104961026  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
104949719  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104945544  nt5e; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104959946  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
104951009  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
104951235  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
104942482  pnp; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104956542  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104944542  hprt1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104968094  inosine-5'-monophosphate dehydrogenase 1b isoform X1 [KO:K00088] [EC:1.1.1.205]
104965117  inosine-5'-monophosphate dehydrogenase 1a isoform X1 [KO:K00088] [EC:1.1.1.205]
104948757  inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104943431  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
104964444  nme6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104959683  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
104963299  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
104945280  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
104946990  ak9; LOW QUALITY PROTEIN: adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104952129  entpd3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104941388  entpd1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
104950180  soluble calcium-activated nucleotidase 1-like isoform X1 [KO:K12304] [EC:3.6.1.6]
104967224  ectonucleoside triphosphate diphosphohydrolase 4-like [KO:K12305] [EC:3.6.1.6]
104960923  entpd5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104960639  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
104952901  U8 snoRNA-decapping enzyme-like [KO:K16855] [EC:3.6.1.62 3.6.1.64]
104943266  itpa; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104941147  nudt2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104955667  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
104953876  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
104950858  gmpr; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
104966818  gda; guanine deaminase [KO:K01487] [EC:3.5.4.3]
104963887  guk1; guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
104949638  guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
104954681  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
104966767  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104957091  ribonucleoside-diphosphate reductase subunit M2 B-like [KO:K10808] [EC:1.17.4.1]
104949330  hddc2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104941578  deoxycytidine kinase-like isoform X1 [KO:K00904] [EC:2.7.1.113]
104952207  dck; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104959066  hddc3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
104962323  adenylate cyclase type 1-like [KO:K08041] [EC:4.6.1.1]
104962256  adcy2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
104952475  adenylate cyclase type 2-like isoform X1 [KO:K08042] [EC:4.6.1.1]
104945720  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
104967529  adenylate cyclase type 6-like [KO:K08046] [EC:4.6.1.1]
104952766  adenylate cyclase type 6-like [KO:K08046] [EC:4.6.1.1]
104955036  adcy8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104960179  adenylate cyclase type 9-like [KO:K08049] [EC:4.6.1.1]
104952968  adenylate cyclase type 9-like [KO:K08049] [EC:4.6.1.1]
104960152  adenylate cyclase type 9-like [KO:K08049] [EC:4.6.1.1]
104945126  gucy1a2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
104949644  gucy1a3; guanylate cyclase soluble subunit alpha-3 isoform X1 [KO:K12318] [EC:4.6.1.2]
104947142  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104949643  gucy1b3; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
104958471  leucine-rich repeat extensin-like protein 3 [KO:K12322] [EC:4.6.1.2]
104962765  retinal guanylyl cyclase 2-like [KO:K12322] [EC:4.6.1.2]
104956250  guanylate cyclase 2G-like [KO:K22600] [EC:4.6.1.2]
104949281  LOW QUALITY PROTEIN: guanylate cyclase 2G-like [KO:K22600] [EC:4.6.1.2]
104967923  atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
104954259  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104947122  soluble guanylate cyclase 88E-like [KO:K01769] [EC:4.6.1.2]
104951040  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like [KO:K13755] [EC:3.1.4.17]
104954336  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like [KO:K13755] [EC:3.1.4.17]
104954337  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like [KO:K13755] [EC:3.1.4.17]
104954769  pde1b; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
104940877  cGMP-dependent 3',5'-cyclic phosphodiesterase-like [KO:K18283] [EC:3.1.4.17]
104963733  cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like [KO:K19021] [EC:3.1.4.17]
104943186  pde3a; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
104964399  pde3b; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
104957103  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13762] [EC:3.1.4.35]
104962348  pde6b; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104964615  cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'-like [KO:K13757] [EC:3.1.4.35]
104962988  pde6c; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
104947444  pde6d; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104959406  pde6g; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
104967129  pde9a; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
104967651  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [KO:K13761] [EC:3.1.4.35]
104952228  pde10a; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104965527  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104949904  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104959348  adenylosuccinate synthetase isozyme 2-like [KO:K01939] [EC:6.3.4.4]
104949709  adssl1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104941035  adenylosuccinate synthetase isozyme 2-like [KO:K01939] [EC:6.3.4.4]
104966048  ampd1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
104950936  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
104960100  AMP deaminase 2-like [KO:K01490] [EC:3.5.4.6]
104964542  AMP deaminase 3-like isoform X1 [KO:K01490] [EC:3.5.4.6]
104962968  ampd3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
104943453  adk; adenosine kinase isoform X1 [KO:K00856] [EC:2.7.1.20]
104948438  adenosine kinase-like [KO:K00856] [EC:2.7.1.20]
104949177  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
104941801  adenosine deaminase CECR1-A-like [KO:K19572] [EC:3.5.4.4]
104950117  adenosine deaminase CECR1-A-like [KO:K19572] [EC:3.5.4.4]
104950118  adenosine deaminase CECR1-A-like [KO:K19572] [EC:3.5.4.4]
104961828  ak1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
104966482  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
104944333  ak4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
104943912  ak6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104967885  ak3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
104961233  ntpcr; cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
104951554  LOW QUALITY PROTEIN: ectonucleotide pyrophosphatase/phosphodiesterase family member 1-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104967247  pde4d; cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
104954895  cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform X1 [KO:K13293] [EC:3.1.4.53]
104956763  cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform X1 [KO:K13293] [EC:3.1.4.53]
104955462  cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like [KO:K13293] [EC:3.1.4.53]
104944849  pde4c; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
104950872  pde4a; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
104946909  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [KO:K13293] [EC:3.1.4.53]
104946204  pde7a; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
104945637  pde7b; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
104958688  pde8b; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
104953025  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A-like [KO:K18437] [EC:3.1.4.53]
104952713  bis(5'-adenosyl)-triphosphatase enpp4-like [KO:K18424] [EC:3.6.1.29]
104956664  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104953586  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104953588  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104941345  uricase-like [KO:K00365] [EC:1.7.3.3]
104964889  ttr; transthyretin isoform X1 [KO:K07127] [EC:3.5.2.17]
104963141  urad; putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
104941656  allantoinase, mitochondrial-like [KO:K01466] [EC:3.5.2.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ncc00030  Pentose phosphate pathway
ncc00220  Arginine biosynthesis
ncc00250  Alanine, aspartate and glutamate metabolism
ncc00260  Glycine, serine and threonine metabolism
ncc00340  Histidine metabolism
ncc00630  Glyoxylate and dicarboxylate metabolism
ncc00730  Thiamine metabolism
ncc00740  Riboflavin metabolism
ncc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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