KEGG   PATHWAY: obi00310
Entry
obi00310                    Pathway                                
Name
Lysine degradation - Octopus bimaculoides (California two-spot octopus)
Class
Metabolism; Amino acid metabolism
Pathway map
obi00310  Lysine degradation
obi00310

Module
obi_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:obi00310]
Other DBs
GO: 0006554
Organism
Octopus bimaculoides (California two-spot octopus) [GN:obi]
Gene
106869155  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1 [KO:K14157] [EC:1.5.1.8 1.5.1.9]
106871909  alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
106879841  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1 [KO:K00825] [EC:2.6.1.7 2.6.1.39]
106879849  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1 [KO:K00825] [EC:2.6.1.7 2.6.1.39]
106874001  2-oxoadipate dehydrogenase complex component E1 [KO:K15791] [EC:1.2.4.-]
106878908  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [KO:K00658] [EC:2.3.1.61]
106870829  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
106884200  glutaryl-CoA dehydrogenase, mitochondrial [KO:K00252] [EC:1.3.8.6]
106883270  trifunctional enzyme subunit alpha, mitochondrial [KO:K07515] [EC:4.2.1.17 1.1.1.211]
106872368  enoyl-CoA hydratase, mitochondrial [KO:K07511] [EC:4.2.1.17]
106868457  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [KO:K00022] [EC:1.1.1.35]
106867347  acetyl-CoA acetyltransferase, cytosolic isoform X1 [KO:K00626] [EC:2.3.1.9]
106875380  acetyl-CoA acetyltransferase A, mitochondrial isoform X1 [KO:K00626] [EC:2.3.1.9]
106884233  hydroxylysine kinase isoform X2 [KO:K18201] [EC:2.7.1.81]
106870392  hydroxylysine kinase [KO:K18201] [EC:2.7.1.81]
106880683  peroxisomal sarcosine oxidase isoform X1 [KO:K00306] [EC:1.5.3.1 1.5.3.7]
106880690  peroxisomal sarcosine oxidase isoform X1 [KO:K00306] [EC:1.5.3.1 1.5.3.7]
128246983  peroxisomal sarcosine oxidase-like [KO:K00306] [EC:1.5.3.1 1.5.3.7]
106870967  calmodulin-lysine N-methyltransferase [KO:K18826] [EC:2.1.1.60]
106883022  uncharacterized protein LOC106883022 [KO:K09188] [EC:2.1.1.354]
106873279  nascent polypeptide-associated complex subunit alpha, muscle-specific form isoform X1 [KO:K09189] [EC:2.1.1.354]
106883719  histone-lysine N-methyltransferase SETD1 [KO:K11422] [EC:2.1.1.354]
106883090  zinc finger protein 391 [KO:K20796] [EC:2.1.1.354]
106884485  uncharacterized protein LOC106884485 isoform X1 [KO:K06101] [EC:2.1.1.354]
106877802  N-lysine methyltransferase SMYD2-A isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
106869377  histone-lysine N-methyltransferase SMYD3 isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
106878284  uncharacterized protein LOC106878284 [KO:K11419] [EC:2.1.1.355]
106867354  serine-rich adhesin for platelets [KO:K11420] [EC:2.1.1.355]
106873585  histone-lysine N-methyltransferase eggless isoform X1 [KO:K11421] [EC:2.1.1.366]
106874217  histone-lysine N-methyltransferase EZH2 [KO:K11430] [EC:2.1.1.356]
106870859  histone-lysine N-methyltransferase SETMAR [KO:K11433] [EC:2.1.1.357]
106878480  histone-lysine N-methyltransferase SETMAR-like [KO:K11433] [EC:2.1.1.357]
128247041  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETMAR-like [KO:K11433] [EC:2.1.1.357]
106877592  uncharacterized protein LOC106877592 [KO:K11423] [EC:2.1.1.359]
106875466  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [KO:K11427] [EC:2.1.1.360]
106878187  LOW QUALITY PROTEIN: N-lysine methyltransferase KMT5A-B [KO:K11428] [EC:2.1.1.361]
106875752  serine-rich adhesin for platelets [KO:K11429] [EC:2.1.1.362]
106868785  putative aldehyde dehydrogenase DhaS isoform X1 [KO:K00128] [EC:1.2.1.3]
106872010  aldehyde dehydrogenase, dimeric NADP-preferring isoform X1 [KO:K00128] [EC:1.2.1.3]
106875588  aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
106876776  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
106875644  4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
106878123  multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [KO:K13646] [EC:1.14.11.4 2.4.1.50 2.4.1.66]
106878759  procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
obi00020  Citrate cycle (TCA cycle)
obi00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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