KEGG   PATHWAY: pcan00230
Entry
pcan00230                   Pathway                                
Name
Purine metabolism - Pomacea canaliculata (golden apple snail)
Class
Metabolism; Nucleotide metabolism
Pathway map
pcan00230  Purine metabolism
pcan00230

Module
pcan_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pcan00230]
pcan_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pcan00230]
pcan_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pcan00230]
pcan_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pcan00230]
pcan_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pcan00230]
pcan_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pcan00230]
pcan_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pcan00230]
Other DBs
GO: 0006163 0042278
Organism
Pomacea canaliculata (golden apple snail) [GN:pcan]
Gene
112562411  ADP-ribose pyrophosphatase, mitochondrial-like isoform X1 [KO:K13988] [EC:3.6.1.13]
112566952  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
112571706  ADP-sugar pyrophosphatase-like [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
112574254  phosphoglucomutase-1-like [KO:K01835] [EC:5.4.2.2]
112558872  phosphoglucomutase-2-like isoform X1 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
112564560  LOW QUALITY PROTEIN: ribose-phosphate pyrophosphokinase 2-like [KO:K00948] [EC:2.7.6.1]
112560691  LOW QUALITY PROTEIN: ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
112560930  amidophosphoribosyltransferase-like [KO:K00764] [EC:2.4.2.14]
112557529  LOW QUALITY PROTEIN: trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
112560129  LOW QUALITY PROTEIN: phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
112560932  LOW QUALITY PROTEIN: multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
112560933  multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
112565714  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
112556652  bifunctional purine biosynthesis protein PURH-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
112577270  LOW QUALITY PROTEIN: adenine phosphoribosyltransferase-like [KO:K00759] [EC:2.4.2.7]
112576917  uncharacterized protein LOC112576917 isoform X1 [KO:K01081] [EC:3.1.3.5]
112564399  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
112563728  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
112557428  5'(3')-deoxyribonucleotidase, cytosolic type-like [KO:K01081] [EC:3.1.3.5]
112577067  uncharacterized protein LOC112577067 isoform X1 [KO:K01081] [EC:3.1.3.5]
112565829  5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
112565830  5'-nucleotidase-like isoform X1 [KO:K19970] [EC:3.1.3.5]
112566051  protein 5NUC-like [KO:K19970] [EC:3.1.3.5]
112565820  5'-nucleotidase-like isoform X1 [KO:K19970] [EC:3.1.3.5]
112571359  uncharacterized protein LOC112571359 [KO:K03783] [EC:2.4.2.1]
112577150  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
112554102  laccase domain-containing protein 1-like [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
112563983  hypoxanthine-guanine phosphoribosyltransferase-like isoform X1 [KO:K00760] [EC:2.4.2.8]
112571939  inosine-5'-monophosphate dehydrogenase 1b-like isoform X1 [KO:K00088] [EC:1.1.1.205]
112574364  nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
112559300  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
112555258  nucleoside diphosphate kinase 7-like isoform X1 [KO:K00940] [EC:2.7.4.6]
112566953  LOW QUALITY PROTEIN: adenylate kinase 9-like [KO:K18533] [EC:2.7.4.3 2.7.4.6]
112565406  ectonucleoside triphosphate diphosphohydrolase 8-like isoform X1 [KO:K01510] [EC:3.6.1.5]
112556813  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
112565036  LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 7-like [KO:K12305] [EC:3.6.1.6]
112570778  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
112572589  LOW QUALITY PROTEIN: uncharacterized protein LOC112572589 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
112571937  uncharacterized protein LOC112571937 isoform X1 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
112574044  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
112558481  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558482  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558485  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558486  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558487  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112560812  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558498  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558796  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558798  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558805  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112558811  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112560136  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112570981  LOW QUALITY PROTEIN: xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112571030  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112570128  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112570129  xanthine dehydrogenase/oxidase-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112553481  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]-like [KO:K01518] [EC:3.6.1.17]
112556668  GMP synthase [glutamine-hydrolyzing]-like isoform X1 [KO:K01951] [EC:6.3.5.2]
112553467  GMP reductase 2-like isoform X1 [KO:K00364] [EC:1.7.1.7]
112555039  guanine deaminase-like isoform X1 [KO:K01487] [EC:3.5.4.3]
112561672  guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
112560420  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
112573879  ribonucleoside-diphosphate reductase subunit M2 B-like [KO:K10808] [EC:1.17.4.1]
112563090  HD domain-containing protein 2-like [KO:K07023] [EC:3.1.3.89]
112556788  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
112564559  LOW QUALITY PROTEIN: adenylate cyclase type 1-like [KO:K08041] [EC:4.6.1.1]
112577004  LOW QUALITY PROTEIN: adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
112563595  LOW QUALITY PROTEIN: adenylate cyclase type 5-like [KO:K08045] [EC:4.6.1.1]
112558934  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
112560072  LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
112572085  LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
112560236  guanylate cyclase soluble subunit beta-1-like [KO:K12319] [EC:4.6.1.2]
112572998  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
112572798  guanylate cyclase soluble subunit beta-2-like isoform X1 [KO:K12319] [EC:4.6.1.2]
112555351  olfactory guanylyl cyclase GC-D-like [KO:K12322] [EC:4.6.1.2]
112571473  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
112560561  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12324] [EC:4.6.1.2]
112559755  LOW QUALITY PROTEIN: soluble guanylate cyclase 88E-like [KO:K01769] [EC:4.6.1.2]
112560182  soluble guanylate cyclase 88E-like isoform X1 [KO:K01769] [EC:4.6.1.2]
112561383  guanylate cyclase 32E-like [KO:K01769] [EC:4.6.1.2]
112564287  LOW QUALITY PROTEIN: speract receptor-like [KO:K01769] [EC:4.6.1.2]
112564293  LOW QUALITY PROTEIN: receptor-type guanylate cyclase Gyc76C-like [KO:K01769] [EC:4.6.1.2]
112566860  LOW QUALITY PROTEIN: receptor-type guanylate cyclase Gyc76C-like [KO:K01769] [EC:4.6.1.2]
112572337  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
112560247  cGMP-dependent 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K18283] [EC:3.1.4.17]
112566973  LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like [KO:K19021] [EC:3.1.4.17]
112556432  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like isoform X1 [KO:K13758]
112563481  cGMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13763] [EC:3.1.4.35]
112569065  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like isoform X1 [KO:K13761] [EC:3.1.4.35]
112558217  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like isoform X1 [KO:K13761] [EC:3.1.4.35]
112573579  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
112556361  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
112563018  LOW QUALITY PROTEIN: dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
112569748  adenylosuccinate synthetase isozyme 2-like [KO:K01939] [EC:6.3.4.4]
112567781  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
112553664  adenosine kinase-like isoform X1 [KO:K00856] [EC:2.7.1.20]
112557648  adenosine kinase-like [KO:K00856] [EC:2.7.1.20]
112561691  LOW QUALITY PROTEIN: adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
112560433  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
112577425  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
112561050  adenylate kinase 2, mitochondrial-like [KO:K00939] [EC:2.7.4.3]
112570728  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
112575194  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
112563008  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
112574241  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
112562739  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
112573681  cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X1 [KO:K13293] [EC:3.1.4.53]
112573480  high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A-like isoform X1 [KO:K18436] [EC:3.1.4.53]
112553600  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like [KO:K18437] [EC:3.1.4.53]
112557785  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
112557159  uncharacterized protein LOC112557159 [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pcan00030  Pentose phosphate pathway
pcan00220  Arginine biosynthesis
pcan00250  Alanine, aspartate and glutamate metabolism
pcan00260  Glycine, serine and threonine metabolism
pcan00340  Histidine metabolism
pcan00630  Glyoxylate and dicarboxylate metabolism
pcan00730  Thiamine metabolism
pcan00740  Riboflavin metabolism
pcan00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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