KEGG   PATHWAY: teo00230
Entry
teo00230                    Pathway                                
Name
Purine metabolism - Tauraco erythrolophus (red-crested turaco)
Class
Metabolism; Nucleotide metabolism
Pathway map
teo00230  Purine metabolism
teo00230

Module
teo_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:teo00230]
teo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:teo00230]
teo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:teo00230]
teo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:teo00230]
teo_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:teo00230]
teo_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:teo00230]
Other DBs
GO: 0006163 0042278
Organism
Tauraco erythrolophus (red-crested turaco) [GN:teo]
Gene
104376028  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104371625  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104380747  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104370208  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104378578  ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
104377747  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104375614  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104369892  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104370341  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104370125  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104378115  ATIC; LOW QUALITY PROTEIN: bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104374338  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104381493  LOW QUALITY PROTEIN: 5'(3')-deoxyribonucleotidase, mitochondrial-like [KO:K01081] [EC:3.1.3.5]
104369973  5'(3')-deoxyribonucleotidase, cytosolic type-like [KO:K01081] [EC:3.1.3.5]
104377409  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104378328  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104379492  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
104384630  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104376390  NT5E; LOW QUALITY PROTEIN: 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104372538  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104369757  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104382260  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104371146  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104384503  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104375188  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
104380968  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
104378631  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
104384420  NME6; LOW QUALITY PROTEIN: nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104369921  nucleoside diphosphate kinase A-like isoform X1 [KO:K00940] [EC:2.7.4.6]
104375122  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104381803  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
104377002  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104372697  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104373952  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104370127  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
104377745  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
104373450  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
104374260  ENTPD5; LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104375783  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104384258  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104369944  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104372229  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104370953  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
104378827  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
104373098  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104371942  ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
104377101  ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104378534  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104377277  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104370950  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104371857  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
104381100  ADCY3; LOW QUALITY PROTEIN: adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
104371518  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104376345  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104373465  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104381221  GUCY1A3; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
104376322  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
104376171  GUCY1B3; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
104374761  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104373395  GUCY2C; LOW QUALITY PROTEIN: heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104378100  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
104373225  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104374717  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104383187  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
104384724  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like [KO:K13755] [EC:3.1.4.17]
104374961  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
104379462  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104375001  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13762] [EC:3.1.4.35]
104374177  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104370076  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
104375524  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104376692  retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104379848  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
104381061  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104382249  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104369659  adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104378298  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104381248  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104382532  AMPD3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
104376082  ADA; LOW QUALITY PROTEIN: adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104383300  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104380305  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
104376239  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104376673  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104377596  AK2; adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
104378355  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
104378780  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
104369718  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104370748  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
104375883  ENTPD2; LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
104373844  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104377756  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104373408  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104380477  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [KO:K13293] [EC:3.1.4.53]
104376044  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
104382580  LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like [KO:K13293] [EC:3.1.4.53]
104376952  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
104382373  cAMP-specific 3',5'-cyclic phosphodiesterase 7B-like [KO:K18436] [EC:3.1.4.53]
104381040  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
104378686  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 [KO:K18437] [EC:3.1.4.53]
104370877  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
104374453  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104379890  PAPSS1; LOW QUALITY PROTEIN: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104378013  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
teo00030  Pentose phosphate pathway
teo00220  Arginine biosynthesis
teo00250  Alanine, aspartate and glutamate metabolism
teo00260  Glycine, serine and threonine metabolism
teo00340  Histidine metabolism
teo00630  Glyoxylate and dicarboxylate metabolism
teo00730  Thiamine metabolism
teo00740  Riboflavin metabolism
teo00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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