KEGG   PATHWAY: tfn04070
Entry
tfn04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Trachypithecus francoisi (Francois's langur)
Class
Environmental Information Processing; Signal transduction
Pathway map
tfn04070  Phosphatidylinositol signaling system
tfn04070

Organism
Trachypithecus francoisi (Francois's langur) [GN:tfn]
Gene
117062348  CALM2; calmodulin-2 [KO:K02183]
117063959  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
117064161  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
117064854  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
117065206  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
117065815  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
117066858  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
117067117  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
117067270  DGKE; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
117067303  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
117067396  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
117068469  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
117068471  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
117068494  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
117068778  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
117068949  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
117069878  [KO:K02183]
117070090  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
117070455  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
117070759  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
117070827  [KO:K02183]
117070833  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
117070870  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
117071511  ITPK1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
117071553  CALM1; calmodulin-1 [KO:K02183]
117072687  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
117072773  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
117074668  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
117074670  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
117075022  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
117075303  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
117075594  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
117076369  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
117077323  MTMR8; LOW QUALITY PROTEIN: myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
117077376  DGKK; LOW QUALITY PROTEIN: diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
117077455  OCRL; inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
117078515  MTMR1; LOW QUALITY PROTEIN: myotubularin-related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
117078516  MTM1; LOW QUALITY PROTEIN: myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
117078737  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase isoform X1 [KO:K15759] [EC:3.1.3.7]
117079004  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
117079553  [KO:K02183]
117079555  IMPA1; LOW QUALITY PROTEIN: inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
117079891  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
117080048  SACM1L; phosphatidylinositide phosphatase SAC1 isoform X1 [KO:K21797] [EC:3.1.3.-]
117080608  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
117080934  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
117080986  IP6K2; inositol hexakisphosphate kinase 2 isoform X1 [KO:K07756] [EC:2.7.4.21]
117081552  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
117081669  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
117081792  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
117082197  CALML3; calmodulin-like protein 3 [KO:K02183]
117082198  CALML5; calmodulin-like protein 5 [KO:K02183]
117082515  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
117082557  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
117082769  IPMK; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
117083173  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
117083208  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
117083761  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
117083855  DGKG; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
117083882  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
117084122  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
117085014  DGKQ; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
117085222  PI4K2B; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
117085370  CDS1; phosphatidate cytidylyltransferase 1 isoform X1 [KO:K00981] [EC:2.7.7.41]
117085960  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
117086074  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
117086699  [KO:K00889] [EC:2.7.1.68]
117086745  [KO:K13024] [EC:2.7.4.24]
117087057  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
117087060  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
117087485  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
117087626  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
117088112  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
117089873  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
117089958  DGKA; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
117090367  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
117090427  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1 [KO:K05861] [EC:3.1.4.11]
117090430  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
117091446  CALM3; calmodulin-3 [KO:K02183]
117091710  PRKCG; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
117091932  ITPKC; inositol-trisphosphate 3-kinase C isoform X1 [KO:K00911] [EC:2.7.1.127]
117091955  [KO:K05860] [EC:3.1.4.11]
117092471  MTMR7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
117092662  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
117092845  INPP5B; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase [KO:K01099] [EC:3.1.3.36]
117093348  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
117093967  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
117094517  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
117094591  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
117094721  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
117095064  [KO:K02183]
117095700  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
117096166  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
117096508  [KO:K00915] [EC:2.7.1.140 2.7.1.151]
117096610  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
117096729  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
117097233  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
117098334  IPPK; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
117098406  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
117098499  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
117099154  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
117099619  INPP4A; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
tfn04020  Calcium signaling pathway
tfn04144  Endocytosis
tfn04151  PI3K-Akt signaling pathway
tfn04510  Focal adhesion
KO pathway
ko04070   

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