KEGG   PATHWAY: zof00600
Entry
zof00600                    Pathway                                
Name
Sphingolipid metabolism - Zingiber officinale (ginger)
Class
Metabolism; Lipid metabolism
Pathway map
zof00600  Sphingolipid metabolism
zof00600

Module
zof_M00100  Sphingosine degradation [PATH:zof00600]
Other DBs
GO: 0006665
Organism
Zingiber officinale (ginger) [GN:zof]
Gene
122056235  long chain base biosynthesis protein 1b-like [KO:K00654] [EC:2.3.1.50]
122025314  long chain base biosynthesis protein 1b-like isoform X1 [KO:K00654] [EC:2.3.1.50]
122027005  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
121976024  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
122027792  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
121992068  long chain base biosynthesis protein 1b-like [KO:K00654] [EC:2.3.1.50]
122029445  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
122030076  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
122031723  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
122031926  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
121995996  long chain base biosynthesis protein 1b-like [KO:K00654] [EC:2.3.1.50]
122033665  long chain base biosynthesis protein 2a-like isoform X1 [KO:K00654] [EC:2.3.1.50]
122034331  long chain base biosynthesis protein 2d [KO:K00654] [EC:2.3.1.50]
121982783  long chain base biosynthesis protein 2a [KO:K00654] [EC:2.3.1.50]
122012373  long chain base biosynthesis protein 2d-like isoform X1 [KO:K00654] [EC:2.3.1.50]
122020197  long chain base biosynthesis protein 1b-like isoform X1 [KO:K00654] [EC:2.3.1.50]
122036271  long chain base biosynthesis protein 1b-like [KO:K00654] [EC:2.3.1.50]
122014222  long chain base biosynthesis protein 2d-like [KO:K00654] [EC:2.3.1.50]
122015281  long chain base biosynthesis protein 2d-like [KO:K00654] [EC:2.3.1.50]
122055458  long chain base biosynthesis protein 1b-like [KO:K00654] [EC:2.3.1.50]
121971627  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
121987359  long chain base biosynthesis protein 2a-like [KO:K00654] [EC:2.3.1.50]
122024921  long chain base biosynthesis protein 1b-like [KO:K00654] [EC:2.3.1.50]
121974930  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
121989735  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
121989737  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
121969804  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
121998684  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
121998686  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
122026218  neutral ceramidase-like [KO:K12349] [EC:3.5.1.23]
121981934  neutral ceramidase-like [KO:K12349] [EC:3.5.1.23]
121985774  neutral ceramidase-like [KO:K12349] [EC:3.5.1.23]
121974918  alkaline ceramidase-like isoform X1 [KO:K04711] [EC:3.5.1.-]
122047657  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
122009380  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
121969794  alkaline ceramidase-like isoform X1 [KO:K04711] [EC:3.5.1.-]
122005207  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
122019068  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
122050695  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
122000918  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
121974296  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122042904  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122027712  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122029994  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
121977753  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
122047425  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122032484  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
121967750  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122034866  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
121969181  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
121999612  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122021278  sphinganine C4-monooxygenase 2-like [KO:K04713] [EC:1.14.18.5]
121970569  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
122052993  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
122025074  sphinganine C4-monooxygenase 2-like [KO:K04713] [EC:1.14.18.5]
121975158  ceramide kinase-like isoform X1 [KO:K04715] [EC:2.7.1.138]
121970050  ceramide kinase-like isoform X1 [KO:K04715] [EC:2.7.1.138]
121967268  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
121967420  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
122021094  sphingosine kinase 2-like isoform X1 [KO:K04718] [EC:2.7.1.91]
122036437  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
122052485  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
122052641  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
121970845  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
121970846  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
122023860  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
122017796  sphingosine-1-phosphate lyase-like isoform X1 [KO:K01634] [EC:4.1.2.27]
122008198  sphingosine-1-phosphate lyase-like [KO:K01634] [EC:4.1.2.27]
122056741  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
121989090  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
121981025  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
121967845  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
121981543  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
121998049  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
122052252  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
122053063  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
121984968  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
121985421  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
122045087  beta-galactosidase-like [KO:K01190] [EC:3.2.1.23]
122040557  beta-galactosidase-like [KO:K01190] [EC:3.2.1.23]
122028922  beta-galactosidase 8-like [KO:K12309] [EC:3.2.1.23]
121970545  beta-galactosidase 8-like isoform X1 [KO:K12309] [EC:3.2.1.23]
122025371  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
122019750  alpha-galactosidase 3-like [KO:K07407] [EC:3.2.1.22]
121990635  alpha-galactosidase 1-like [KO:K07407] [EC:3.2.1.22]
121991494  alpha-galactosidase 1-like [KO:K07407] [EC:3.2.1.22]
121977440  alpha-galactosidase 1-like [KO:K07407] [EC:3.2.1.22]
121978074  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
121992744  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
121995388  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
121995389  alpha-galactosidase 1-like [KO:K07407] [EC:3.2.1.22]
121996707  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
121969691  alpha-galactosidase 1-like [KO:K07407] [EC:3.2.1.22]
122021498  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
122036989  alpha-galactosidase-like isoform X1 [KO:K07407] [EC:3.2.1.22]
122023496  alpha-galactosidase 3-like [KO:K07407] [EC:3.2.1.22]
122024153  alpha-galactosidase 3-like [KO:K07407] [EC:3.2.1.22]
122041957  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
122006959  beta-hexosaminidase 1-like isoform X1 [KO:K12373] [EC:3.2.1.52]
121977975  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
122046481  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
121980535  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
121984439  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
121973606  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
122002717  beta-hexosaminidase 1-like [KO:K12373] [EC:3.2.1.52]
121974673  prosaposin-like [KO:K12382]
122017135  proactivator polypeptide-like 1 [KO:K12382]
122006174  prosaposin-like isoform X1 [KO:K12382]
121969539  prosaposin-like [KO:K12382]
121982681  prosaposin-like [KO:K12382]
122012594  proactivator polypeptide-like 1 [KO:K12382]
122038209  prosaposin-like [KO:K12382]
Compound
C00065  L-Serine
C00154  Palmitoyl-CoA
C00195  N-Acylsphingosine
C00319  Sphingosine
C00346  Ethanolamine phosphate
C00550  Sphingomyelin
C00836  Sphinganine
C01120  Sphinganine 1-phosphate
C01190  Glucosylceramide
C01290  Lactosylceramide
C01747  Psychosine
C02686  Galactosylceramide
C02934  3-Dehydrosphinganine
C02960  Ceramide 1-phosphate
C03108  D-Glucosylsphingosine
C03272  Globoside
C03405  Lactosylceramide sulfate
C03640  Sphingosyl-phosphocholine
C04730  GM3
C04737  alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884  N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911  D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681  Ceramide 2-aminoethylphosphonate
C06062  Ceramide phosphoethanolamine
C06124  Sphingosine 1-phosphate
C06125  Sulfatide
C06126  Digalactosylceramide
C06127  Digalactosylceramide sulfate
C06128  GM4
C06135  GA2
C06136  GA1
C12126  Dihydroceramide
C12144  Phytosphingosine
C12145  Phytoceramide
C22467  Gangliotriaosylceramide-II3 sulfate
Reference
PMID:12011104
  Authors
Merrill AH Jr.
  Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
  Journal
J Biol Chem 277:25843-6 (2002)
DOI:10.1074/jbc.R200009200
Reference
PMID:10652340
  Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
  Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
  Journal
J Biol Chem 275:3462-8 (2000)
DOI:10.1074/jbc.275.5.3462
Reference
PMID:11305904
  Authors
Hannun YA, Luberto C, Argraves KM.
  Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
  Journal
Biochemistry 40:4893-903 (2001)
DOI:10.1021/bi002836k
Reference
PMID:1495423
  Authors
Merrill AH Jr, Wang E.
  Title
Enzymes of ceramide biosynthesis.
  Journal
Methods Enzymol 209:427-37 (1992)
DOI:10.1016/0076-6879(92)09053-6
Reference
PMID:8457204
  Authors
Hirschberg K, Rodger J, Futerman AH.
  Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
  Journal
Biochem J 290 ( Pt 3):751-7 (1993)
DOI:10.1042/bj2900751
Reference
PMID:10366774
  Authors
Dickson RC, Lester RL.
  Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1438:305-21 (1999)
DOI:10.1016/S1388-1981(99)00068-2
Related
pathway
zof00260  Glycine, serine and threonine metabolism
zof00601  Glycosphingolipid biosynthesis - lacto and neolacto series
zof00603  Glycosphingolipid biosynthesis - globo and isoglobo series
zof00604  Glycosphingolipid biosynthesis - ganglio series
KO pathway
ko00600   
LinkDB

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