Homo sapiens (human): 5423
Help
Entry
5423 CDS
T01001
Symbol
POLB
Name
(RefSeq) DNA polymerase beta
KO
K02330
DNA polymerase beta [EC:
2.7.7.7
4.2.99.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03410
Base excision repair
hsa05166
Human T-cell leukemia virus 1 infection
hsa05203
Viral carcinogenesis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06504
Base excision repair
Element
N00511
HTLV-1 Tax to E47-mediated transcription
N01433
Base excision and strand cleavage by monofunctional glycosylase
N01434
Base excision and strand cleavage by bifunctional glycosylase
N01435
Base excision and strand cleavage by NEIL glycosylase
N01436
Long patch BER
N01437
Short patch BER
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03410 Base excision repair
5423 (POLB)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
5423 (POLB)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
5423 (POLB)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
5423 (POLB)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
5423 (POLB)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Short Patch-BER factors
5423 (POLB)
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
X-family DNA polymerases
5423 (POLB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_pol_B_palm
HHH_8
DNA_pol_lambd_f
DNA_pol_B_thumb
HHH_5
HHH
Cdd1
HHH_2
NTP_transf_2
Motif
Other DBs
NCBI-GeneID:
5423
NCBI-ProteinID:
NP_002681
OMIM:
174760
HGNC:
9174
Ensembl:
ENSG00000070501
UniProt:
P06746
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:42338494..42371808
Genome browser
AA seq
335 aa
AA seq
DB search
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
NT seq
1008 nt
NT seq
+upstream
nt +downstream
nt
atgagcaaacggaaggcgccgcaggagactctcaacgggggaatcaccgacatgctcaca
gaactcgcaaactttgagaagaacgtgagccaagctatccacaagtacaatgcttacaga
aaagcagcatctgttatagcaaaatacccacacaaaataaagagtggagctgaagctaag
aaattgcctggagtaggaacaaaaattgctgaaaagattgatgagtttttagcaactgga
aaattacgtaaactggaaaagattcggcaggatgatacgagttcatccatcaatttcctg
actcgagttagtggcattggtccatctgctgcaaggaagtttgtagatgaaggaattaaa
acactagaagatctcagaaaaaatgaagataaattgaaccatcatcagcgaattgggctg
aaatattttggggactttgaaaaaagaattcctcgtgaagagatgttacaaatgcaagat
attgtactaaatgaagttaaaaaagtggattctgaatacattgctacagtctgtggcagt
ttcagaagaggtgcagagtccagtggtgacatggatgttctcctgacccatcccagcttc
acttcagaatcaaccaaacagccaaaactgttacatcaggttgtggagcagttacaaaag
gttcattttatcacagataccctgtcaaagggtgagacaaagttcatgggtgtttgccag
cttcccagtaaaaatgatgaaaaagaatatccacacagaagaattgatatcaggttgata
cccaaagatcagtattactgtggtgttctctatttcactgggagtgatattttcaataag
aatatgagggctcatgccctagaaaagggtttcacaatcaatgagtacaccatccgtccc
ttgggagtcactggagttgcaggagaacccctgccagtggatagtgaaaaagacatcttt
gattacatccagtggaaataccgggaacccaaggaccggagcgaatga
Homo sapiens (human): 3932
Help
Entry
3932 CDS
T01001
Symbol
LCK, IMD22, LSK, YT16, p56lck, pp58lck
Name
(RefSeq) LCK proto-oncogene, Src family tyrosine kinase
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04064
NF-kappa B signaling pathway
hsa04380
Osteoclast differentiation
hsa04650
Natural killer cell mediated cytotoxicity
hsa04658
Th1 and Th2 cell differentiation
hsa04659
Th17 cell differentiation
hsa04660
T cell receptor signaling pathway
hsa05135
Yersinia infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05340
Primary immunodeficiency
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06183
Yersinia
nt06537
TCR/BCR signaling
Element
N00511
HTLV-1 Tax to E47-mediated transcription
N01106
TCR-PLCG-ITPR signaling pathway
N01107
Yersinia YopH to TCR-NFAT signaling pathway
Disease
H00093
Combined immunodeficiency
Drug target
Dasatinib (
DG00714
):
D03658
<JP>
D06414
<JP/US>
D12609
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
3932 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
3932 (LCK)
04660 T cell receptor signaling pathway
3932 (LCK)
04658 Th1 and Th2 cell differentiation
3932 (LCK)
04659 Th17 cell differentiation
3932 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
3932 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
3932 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
3932 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
3932 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
3932 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
3932 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
3932 (LCK)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
3932 (LCK)
Protein kinases [BR:
hsa01001
]
Non-receptor tyrosine kinases
SRC family
3932 (LCK)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
3932 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
3932
NCBI-ProteinID:
NP_001036236
OMIM:
153390
HGNC:
6524
Ensembl:
ENSG00000182866
UniProt:
P06239
A0A0S2Z3Y8
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:32251265..32286165
Genome browser
AA seq
509 aa
AA seq
DB search
MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKER
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtggctgcagctcacacccggaagatgactggatggaaaacatcgatgtgtgt
gagaactgccattatcccatagtcccactggatggcaagggcacgctgctcatccgaaat
ggctctgaggtgcgggacccactggttacctacgaaggctccaatccgccggcttcccca
ctgcaagacaacctggttatcgctctgcacagctatgagccctctcacgacggagatctg
ggctttgagaagggggaacagctccgcatcctggagcagagcggcgagtggtggaaggcg
cagtccctgaccacgggccaggaaggcttcatccccttcaattttgtggccaaagcgaac
agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgcggagcggcag
ctcctggcgcccgggaacactcacggctccttcctcatccgggagagcgagagcaccgcg
ggatcgttttcactgtcggtccgggacttcgaccagaaccagggagaggtggtgaaacat
tacaagatccgtaatctggacaacggtggcttctacatctcccctcgaatcacttttccc
ggcctgcatgaactggtccgccattacaccaatgcttcagatgggctgtgcacacggttg
agccgcccctgccagacccagaagccccagaagccgtggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggacagttcggggaggtgtgg
atggggtactacaacgggcacacgaaggtggcggtgaagagcctgaagcagggcagcatg
tccccggacgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg
gttcggctctacgctgtggtcacccaggagcccatctacatcatcactgaatacatggag
aatgggagtctagtggattttctcaagaccccttcaggcatcaagttgaccatcaacaaa
ctcctggacatggcagcccaaattgcagaaggcatggcattcattgaagagcggaattat
attcatcgtgaccttcgggctgccaacattctggtgtctgacaccctgagctgcaagatt
gcagactttggcctagcacgcctcattgaggacaacgagtacacagccagggagggggcc
aagtttcccattaagtggacagcgccagaagccattaactacgggacattcaccatcaag
tcagatgtgtggtcttttgggatcctgctgacggaaattgtcacccacggccgcatccct
tacccagggatgaccaacccggaggtgattcagaacctggagcgaggctaccgcatggtg
cgccctgacaactgtccagaggagctgtaccaactcatgaggctgtgctggaaggagcgc
ccagaggaccggcccacctttgactacctgcgcagtgtgctggaggacttcttcacggcc
acagagggccagtaccagcctcagccttga
Homo sapiens (human): 581
Help
Entry
581 CDS
T01001
Symbol
BAX, BCL2L4
Name
(RefSeq) BCL2 associated X, apoptosis regulator
KO
K02159
apoptosis regulator BAX
Organism
hsa
Homo sapiens (human)
Pathway
hsa01521
EGFR tyrosine kinase inhibitor resistance
hsa01522
Endocrine resistance
hsa01524
Platinum drug resistance
hsa04071
Sphingolipid signaling pathway
hsa04115
p53 signaling pathway
hsa04141
Protein processing in endoplasmic reticulum
hsa04210
Apoptosis
hsa04211
Longevity regulating pathway
hsa04215
Apoptosis - multiple species
hsa04217
Necroptosis
hsa04722
Neurotrophin signaling pathway
hsa04932
Non-alcoholic fatty liver disease
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05130
Pathogenic Escherichia coli infection
hsa05131
Shigellosis
hsa05132
Salmonella infection
hsa05152
Tuberculosis
hsa05160
Hepatitis C
hsa05161
Hepatitis B
hsa05162
Measles
hsa05163
Human cytomegalovirus infection
hsa05164
Influenza A
hsa05165
Human papillomavirus infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05203
Viral carcinogenesis
hsa05210
Colorectal cancer
hsa05212
Pancreatic cancer
hsa05213
Endometrial cancer
hsa05214
Glioma
hsa05216
Thyroid cancer
hsa05217
Basal cell carcinoma
hsa05218
Melanoma
hsa05220
Chronic myeloid leukemia
hsa05222
Small cell lung cancer
hsa05223
Non-small cell lung cancer
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
hsa05417
Lipid and atherosclerosis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06170
Influenza A virus (IAV)
nt06231
Apoptosis (cancer)
nt06240
Transcription (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06262
Pancreatic cancer
nt06263
Hepatocellular carcinoma
nt06265
Bladder cancer
nt06266
Non-small cell lung cancer
nt06267
Small cell lung cancer
nt06268
Melanoma
nt06269
Basal cell carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06273
Glioma
nt06274
Thyroid cancer
nt06276
Chronic myeloid leukemia
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
nt06524
Apoptosis
Element
N00098
Intrinsic apoptotic pathway
N00099
Mutation-inactivated BAX to apoptotic pathway
N00100
BCL2-overexpression to intrinsic apoptotic pathway
N00115
Mutation-inactivated TP53 to transcription
N00146
Crosstalk between extrinsic and intrinsic apoptotic pathways
N00164
KSHV vBCL2 to crosstalk between extrinsic and intrinsic apoptotic pathways
N00223
EBV EBNA1 to p53-mediated transcription
N00263
EBV EBNA3C to p53-mediated transcription
N00426
HCMV UL37x1 to crosstalk between extrinsic and intrinsic apoptotic pathways
N00449
HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
N00450
HIV Tat to intrinsic apoptotic pathway
N00454
HIV Vpr to intrinsic apoptotic pathway
N00478
EBV BARF1 to intrinsic apoptotic pathway
N00481
EBV BZLF1 to p53-mediated transcription
N00511
HTLV-1 Tax to E47-mediated transcription
N00534
HBV HBx to Crosstalk between extrinsic and intrinsic apoptotic pathways
N00535
HBV HBx to p53-mediated transcription
N00938
Escherichia NleH to intrinsic apoptotic pathway
N00950
Shigella FimA to crosstalk between extrinsic and intrinsic apoptotic pathways
N00982
Mutation-caused aberrant Htt to p53-mediated transcription
N01005
Mutation-caused aberrant Abeta to crosstalk between extrinsic and intrinsic apoptotic pathways
N01049
Mutation-inactivated PRKN to intrinsic apoptotic pathway
N01050
Mutation-inactivated PINK1 to intrinsic apoptotic pathway
N01051
Mutation-inactivated DJ1 to intrinsic apoptotic pathway
N01135
Mutation-caused aberrant SOD1 to intrinsic apoptotic pathway
Disease
H00020
Colorectal cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
581 (BAX)
09130 Environmental Information Processing
09132 Signal transduction
04071 Sphingolipid signaling pathway
581 (BAX)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
581 (BAX)
04215 Apoptosis - multiple species
581 (BAX)
04217 Necroptosis
581 (BAX)
04115 p53 signaling pathway
581 (BAX)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
581 (BAX)
09149 Aging
04211 Longevity regulating pathway
581 (BAX)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
581 (BAX)
05202 Transcriptional misregulation in cancer
581 (BAX)
05203 Viral carcinogenesis
581 (BAX)
09162 Cancer: specific types
05210 Colorectal cancer
581 (BAX)
05212 Pancreatic cancer
581 (BAX)
05225 Hepatocellular carcinoma
581 (BAX)
05226 Gastric cancer
581 (BAX)
05214 Glioma
581 (BAX)
05216 Thyroid cancer
581 (BAX)
05220 Chronic myeloid leukemia
581 (BAX)
05217 Basal cell carcinoma
581 (BAX)
05218 Melanoma
581 (BAX)
05213 Endometrial cancer
581 (BAX)
05224 Breast cancer
581 (BAX)
05222 Small cell lung cancer
581 (BAX)
05223 Non-small cell lung cancer
581 (BAX)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
581 (BAX)
05170 Human immunodeficiency virus 1 infection
581 (BAX)
05161 Hepatitis B
581 (BAX)
05160 Hepatitis C
581 (BAX)
05164 Influenza A
581 (BAX)
05162 Measles
581 (BAX)
05168 Herpes simplex virus 1 infection
581 (BAX)
05163 Human cytomegalovirus infection
581 (BAX)
05167 Kaposi sarcoma-associated herpesvirus infection
581 (BAX)
05169 Epstein-Barr virus infection
581 (BAX)
05165 Human papillomavirus infection
581 (BAX)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
581 (BAX)
05132 Salmonella infection
581 (BAX)
05131 Shigellosis
581 (BAX)
05152 Tuberculosis
581 (BAX)
09164 Neurodegenerative disease
05012 Parkinson disease
581 (BAX)
05014 Amyotrophic lateral sclerosis
581 (BAX)
05016 Huntington disease
581 (BAX)
05020 Prion disease
581 (BAX)
05022 Pathways of neurodegeneration - multiple diseases
581 (BAX)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
581 (BAX)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
581 (BAX)
04933 AGE-RAGE signaling pathway in diabetic complications
581 (BAX)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
581 (BAX)
01524 Platinum drug resistance
581 (BAX)
01522 Endocrine resistance
581 (BAX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
hsa03029
]
581 (BAX)
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
581 (BAX)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Mitochondrial dynamics
Fission and Fusion factors
581 (BAX)
Transporters [BR:
hsa02000
]
Other transporters
Pores ion channels [TC:
1
]
581 (BAX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Bcl-2
TetR_C_30
Motif
Other DBs
NCBI-GeneID:
581
NCBI-ProteinID:
NP_620116
OMIM:
600040
HGNC:
959
Ensembl:
ENSG00000087088
UniProt:
Q07812
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:48954875..48961798
Genome browser
AA seq
192 aa
AA seq
DB search
MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
LTASLTIWKKMG
NT seq
579 nt
NT seq
+upstream
nt +downstream
nt
atggacgggtccggggagcagcccagaggcggggggcccaccagctctgagcagatcatg
aagacaggggcccttttgcttcagggtttcatccaggatcgagcagggcgaatggggggg
gaggcacccgagctggccctggacccggtgcctcaggatgcgtccaccaagaagctgagc
gagtgtctcaagcgcatcggggacgaactggacagtaacatggagctgcagaggatgatt
gccgccgtggacacagactccccccgagaggtctttttccgagtggcagctgacatgttt
tctgacggcaacttcaactggggccgggttgtcgcccttttctactttgccagcaaactg
gtgctcaaggccctgtgcaccaaggtgccggaactgatcagaaccatcatgggctggaca
ttggacttcctccgggagcggctgttgggctggatccaagaccagggtggttgggacggc
ctcctctcctactttgggacgcccacgtggcagaccgtgaccatctttgtggcgggagtg
ctcaccgcctcactcaccatctggaagaagatgggctga
Homo sapiens (human): 1031
Help
Entry
1031 CDS
T01001
Symbol
CDKN2C, INK4C, p18, p18-INK4C
Name
(RefSeq) cyclin dependent kinase inhibitor 2C
KO
K06622
cyclin-dependent kinase inhibitor 2C
Organism
hsa
Homo sapiens (human)
Pathway
hsa01522
Endocrine resistance
hsa04110
Cell cycle
hsa04934
Cushing syndrome
hsa05166
Human T-cell leukemia virus 1 infection
hsa05202
Transcriptional misregulation in cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06240
Transcription (cancer)
nt06360
Cushing syndrome
Element
N00120
MLL-ENL fusion to transcriptional activation
N00290
Mutation-inactivated MEN1 to transcription
N00511
HTLV-1 Tax to E47-mediated transcription
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
1031 (CDKN2C)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
1031 (CDKN2C)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
1031 (CDKN2C)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
1031 (CDKN2C)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
1031 (CDKN2C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ank_2
Ank_4
Ank
Ank_5
Ank_3
Ank_KRIT1
DUF1843
ANK_LRRK2
Motif
Other DBs
NCBI-GeneID:
1031
NCBI-ProteinID:
NP_001253
OMIM:
603369
HGNC:
1789
Ensembl:
ENSG00000123080
UniProt:
P42773
Q6ICV4
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:50960745..50974634
Genome browser
AA seq
168 aa
AA seq
DB search
MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG
ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE
FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
NT seq
507 nt
NT seq
+upstream
nt +downstream
nt
atggccgagccttgggggaacgagttggcgtccgcagctgccaggggggacctagagcaa
cttactagtttgttgcaaaataatgtaaacgtcaatgcacaaaatggatttggaaggact
gcgctgcaggttatgaaacttggaaatcccgagattgccaggagactgctacttagaggt
gctaatcccgatttgaaagaccgaactggtttcgctgtcattcatgatgcggccagagca
ggtttcctggacactttacagactttgctggagtttcaagctgatgttaacatcgaggat
aatgaagggaacctgcccttgcacttggctgccaaagaaggccacctccgggtggtggag
ttcctggtgaagcacacggccagcaatgtggggcatcggaaccataagggggacaccgcc
tgtgatttggccaggctctatgggaggaatgaggttgttagcctgatgcaggcaaacggg
gctgggggagccacaaatcttcaataa
DBGET
integrated database retrieval system
