KEGG   PATHWAY: caua04540
Entry
caua04540                   Pathway                                
Name
Gap junction - Carassius auratus (goldfish)
Description
Gap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels', each containing six connexins, contributed by each neighboring cell. These channels permit the direct transfer of small molecules including ions, amino acids, nucleotides, second messengers and other metabolites between adjacent cells. Gap junctional communication is essential for many physiological events, including embryonic development, electrical coupling, metabolic transport, apoptosis, and tissue homeostasis. Communication through Gap Junction is sensitive to a variety of stimuli, including changes in the level of intracellular Ca2+, pH, transjunctional applied voltage and phosphorylation/dephosphorylation processes. This figure represents the possible activation routes of different protein kinases involved in Cx43 and Cx36 phosphorylation.
Class
Cellular Processes; Cellular community - eukaryotes
Pathway map
caua04540  Gap junction
caua04540

Other DBs
GO: 0005921
Organism
Carassius auratus (goldfish) [GN:caua]
Gene
113091731  gap junction alpha-1 protein-like [KO:K07372]
113060742  gap junction alpha-1 protein-like [KO:K07372]
113075897  gap junction alpha-1 protein-like [KO:K07372]
113094920  gap junction alpha-1 protein-like [KO:K07372]
113120695  gap junction alpha-1 protein [KO:K07372]
113086596  gap junction alpha-1 protein-like [KO:K07372]
113060377  gap junction delta-2 protein-like [KO:K07373]
113076627  gap junction delta-2 protein-like [KO:K07373]
113049577  gap junction delta-2 protein-like [KO:K07373]
113121181  gap junction delta-2 protein [KO:K07373]
113115346  gap junction delta-2 protein-like [KO:K07373]
113063011  gap junction delta-2 protein-like [KO:K07373]
113098371  gap junction delta-2 protein-like isoform X1 [KO:K07373]
113037855  gap junction delta-2 protein-like [KO:K07373]
113051953  gap junction delta-2 protein-like [KO:K07373]
113116955  gap junction delta-2 protein-like [KO:K07373]
113105691  gap junction delta-2 protein-like [KO:K07373]
113054030  lysophosphatidic acid receptor 1-A-like [KO:K04289]
113109577  lysophosphatidic acid receptor 1-A [KO:K04289]
113048219  guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
113066916  guanine nucleotide-binding protein G(i) subunit alpha-1-like [KO:K04630]
113093906  guanine nucleotide-binding protein G(k) subunit alpha-like [KO:K04630]
113107576  guanine nucleotide-binding protein G(k) subunit alpha-like [KO:K04630]
113107607  guanine nucleotide-binding protein G(k) subunit alpha-like [KO:K04630]
113055340  guanine nucleotide-binding protein G(i) subunit alpha-2-like [KO:K04630]
113061871  guanine nucleotide-binding protein G(i) subunit alpha-1-like [KO:K04630]
113043360  guanine nucleotide-binding protein G(i) subunit alpha-1-like [KO:K04630]
113050132  guanine nucleotide-binding protein G(i) subunit alpha-2-like [KO:K04630]
113050217  guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
113110925  guanine nucleotide-binding protein G(i) subunit alpha-2-like [KO:K04630]
113103847  guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
113047958  uncharacterized protein LOC113047958 [KO:K04359]
113067655  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
113050994  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
113065132  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
113046740  uncharacterized protein LOC113046740 [KO:K04359]
113039942  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
113065075  adenylate cyclase, terminal-differentiation specific-like isoform X1 [KO:K17386]
113039864  uncharacterized protein LOC113039864 [KO:K17386]
113092932  platelet-derived growth factor C-like [KO:K05450]
113114617  pdgfd; platelet-derived growth factor D isoform X1 [KO:K05450]
113057766  platelet-derived growth factor C-like [KO:K05450]
113057995  platelet-derived growth factor C-like isoform X1 [KO:K05450]
113058810  platelet-derived growth factor D-like isoform X1 [KO:K05450]
113090041  platelet-derived growth factor D-like [KO:K05450]
113114148  pro-epidermal growth factor-like [KO:K04357]
113078680  platelet-derived growth factor receptor alpha-like [KO:K04363] [EC:2.7.10.1]
113120986  platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
113063319  platelet-derived growth factor receptor alpha-like [KO:K04363] [EC:2.7.10.1]
113113654  platelet-derived growth factor receptor beta-like [KO:K05089] [EC:2.7.10.1]
113069557  platelet-derived growth factor receptor beta-like isoform X1 [KO:K05089] [EC:2.7.10.1]
113092711  epidermal growth factor receptor-like [KO:K04361] [EC:2.7.10.1]
113042612  melanoma receptor tyrosine-protein kinase-like [KO:K04361] [EC:2.7.10.1]
113114389  epidermal growth factor receptor-like isoform X1 [KO:K04361] [EC:2.7.10.1]
113045981  epidermal growth factor receptor-like isoform X1 [KO:K04361] [EC:2.7.10.1]
113047808  growth factor receptor-bound protein 2-like [KO:K04364]
113050680  growth factor receptor-bound protein 2 isoform X1 [KO:K04364]
113097902  growth factor receptor-bound protein 2-like isoform X1 [KO:K04364]
113046804  growth factor receptor-bound protein 2-like [KO:K04364]
113112475  son of sevenless homolog 2-like [KO:K03099]
113056783  sos2; son of sevenless homolog 2 [KO:K03099]
113110612  son of sevenless homolog 1-like [KO:K03099]
113110616  son of sevenless homolog 1-like [KO:K03099]
113106249  GTPase HRas [KO:K02833]
113067303  GTPase HRas-like [KO:K02833]
113043599  GTPase HRas-like [KO:K02833]
113051345  GTPase HRas-like [KO:K02833]
113067076  ras-like protein isoform X1 [KO:K07827]
113043474  GTPase HRas-like [KO:K07827]
113043560  GTPase KRas [KO:K07827]
113046915  GTPase HRas-like [KO:K07827]
113106980  GTPase NRas-like [KO:K07828]
113071752  GTPase NRas [KO:K07828]
113083541  GTPase NRas-like [KO:K07828]
113054940  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
113068641  RAF proto-oncogene serine/threonine-protein kinase-like isoform X1 [KO:K04366] [EC:2.7.11.1]
113061451  dual specificity mitogen-activated protein kinase kinase 1-like [KO:K04368] [EC:2.7.12.2]
113118360  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
113045154  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
113045216  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
113064928  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
113039644  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
113047409  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
113068089  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
113072016  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
113046952  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
113041276  proto-oncogene tyrosine-protein kinase Src-like isoform X1 [KO:K05704] [EC:2.7.10.2]
113065632  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
113092298  mitogen-activated protein kinase kinase kinase 2-like [KO:K04420] [EC:2.7.11.25]
113050870  mitogen-activated protein kinase kinase kinase 2-like [KO:K04420] [EC:2.7.11.25]
113106008  map2k5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1 [KO:K04463] [EC:2.7.12.2]
113056399  mitogen-activated protein kinase 7-like isoform X1 [KO:K04464] [EC:2.7.11.24]
113111996  mitogen-activated protein kinase 7-like [KO:K04464] [EC:2.7.11.24]
113041559  tubulin alpha chain-like [KO:K07374]
113041561  tubulin alpha-1A chain [KO:K07374]
113092449  tubulin alpha-8 chain-like [KO:K07374]
113113059  tubulin alpha-8 chain-like [KO:K07374]
113041562  tubulin alpha-1C chain-like [KO:K07374]
113054682  tubulin alpha chain, testis-specific-like isoform X1 [KO:K07374]
113107532  tubulin alpha-8 chain-like [KO:K07374]
113107705  tubulin alpha-8 chain-like [KO:K07374]
113095990  tubulin alpha chain-like [KO:K07374]
113069256  tubulin alpha-1B chain-like [KO:K07374]
113069257  tubulin alpha-1A chain-like [KO:K07374]
113108882  tubulin alpha chain-like [KO:K07374]
113044579  tubulin alpha chain-like [KO:K07374]
113050930  tubulin alpha-1A chain-like [KO:K07374]
113050931  tubulin alpha chain [KO:K07374]
113057264  tubulin alpha-8 chain-like [KO:K07374]
113072092  tubulin alpha chain, testis-specific-like isoform X1 [KO:K07374]
113053565  tubulin alpha chain-like [KO:K07374]
113053566  tubulin alpha-1D chain-like [KO:K07374]
113065726  tubulin alpha-1A chain isoform X1 [KO:K07374]
113065727  tubulin alpha-1B chain [KO:K07374]
113065742  tubulin alpha-1C chain-like [KO:K07374]
113091408  tubulin alpha chain [KO:K07374]
113091416  tubulin alpha-1A chain-like [KO:K07374]
113053694  tubulin beta-4B chain-like [KO:K07375]
113066319  tubulin beta-5 chain-like isoform X1 [KO:K07375]
113075605  tubulin beta-4B chain isoform X1 [KO:K07375]
113107305  tubulin beta-1 chain-like [KO:K07375]
113042220  tubulin beta-5 chain [KO:K07375]
113067674  tubulin beta-4B chain-like [KO:K07375]
113113767  tubulin beta-4B chain-like [KO:K07375]
113049375  tubulin beta-4B chain [KO:K07375]
113077855  tubulin beta chain-like isoform X1 [KO:K07375]
113050263  tubulin beta chain-like [KO:K07375]
113045123  tubulin beta-4B chain-like [KO:K07375]
113070987  tubulin beta-1 chain [KO:K07375]
113051735  tubulin beta-4B chain-like [KO:K07375]
113046131  tubulin beta chain-like [KO:K07375]
113105093  tubulin beta chain-like [KO:K07375]
113039845  tubulin beta chain-like [KO:K07375]
113060002  tubulin beta chain isoform X1 [KO:K07375]
113047391  casein kinase I isoform X1 [KO:K08959] [EC:2.7.11.1]
113055965  casein kinase I-like [KO:K08959] [EC:2.7.11.1]
113070981  casein kinase I [KO:K08959] [EC:2.7.11.1]
113098980  casein kinase I-like isoform X1 [KO:K08959] [EC:2.7.11.1]
113064175  casein kinase I-like [KO:K08959] [EC:2.7.11.1]
113111619  casein kinase I [KO:K08959] [EC:2.7.11.1]
113111630  casein kinase I [KO:K08959] [EC:2.7.11.1]
113094561  cyclin-dependent kinase 1-like [KO:K02087] [EC:2.7.11.22 2.7.11.23]
113117193  cyclin-dependent kinase 1 [KO:K02087] [EC:2.7.11.22 2.7.11.23]
113067044  tight junction protein ZO-1-like isoform X1 [KO:K05701]
113043481  tight junction protein ZO-1-like isoform X1 [KO:K05701]
113051534  tight junction protein ZO-1-like isoform X1 [KO:K05701]
113105952  tight junction protein ZO-1-like isoform X1 [KO:K05701]
113076930  beta-1 adrenergic receptor-like [KO:K04141]
113111574  beta-1 adrenergic receptor-like [KO:K04141]
113078136  D(1) dopamine receptor-like [KO:K04144]
113114297  D(1) dopamine receptor-like [KO:K04144]
113057841  D(1) dopamine receptor [KO:K04144]
113063877  D(1)-like dopamine receptor [KO:K04144]
113038336  D(1)-like dopamine receptor [KO:K04144]
113050265  guanine nucleotide-binding protein G(s) subunit alpha-like isoform X1 [KO:K04632]
113105096  guanine nucleotide-binding protein G(s) subunit alpha isoform X1 [KO:K04632]
113043117  uncharacterized protein LOC113043117 [KO:K04145]
113043269  uncharacterized protein LOC113043269 [KO:K04145]
113049788  D(2)-like dopamine receptor [KO:K04145]
113115093  D(2)-like dopamine receptor [KO:K04145]
113081886  D(2)-like dopamine receptor [KO:K04145]
113058429  D(2)-like dopamine receptor [KO:K04145]
113059411  D(2)-like dopamine receptor [KO:K04145]
113121087  adenylate cyclase type 1-like [KO:K08041] [EC:4.6.1.1]
113063272  adenylate cyclase type 1-like isoform X1 [KO:K08041] [EC:4.6.1.1]
113039324  adenylate cyclase type 1-like [KO:K08041] [EC:4.6.1.1]
113046191  adenylate cyclase type 1-like [KO:K08041] [EC:4.6.1.1]
113119536  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
113116166  adenylate cyclase type 2-like isoform X1 [KO:K08042] [EC:4.6.1.1]
113090787  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
113120648  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
113097331  adenylate cyclase type 3-like isoform X1 [KO:K08043] [EC:4.6.1.1]
113116527  adenylate cyclase type 3-like isoform X1 [KO:K08043] [EC:4.6.1.1]
113059808  adenylate cyclase type 3-like isoform X1 [KO:K08043] [EC:4.6.1.1]
113105408  adenylate cyclase type 2-like [KO:K08044] [EC:4.6.1.1]
113096274  adenylate cyclase type 4-like [KO:K08044] [EC:4.6.1.1]
113108405  adenylate cyclase type 5-like isoform X1 [KO:K08045] [EC:4.6.1.1]
113069207  adenylate cyclase type 5-like isoform X1 [KO:K08045] [EC:4.6.1.1]
113053059  adenylate cyclase type 5-like isoform X1 [KO:K08045] [EC:4.6.1.1]
113041064  adenylate cyclase type 6-like [KO:K08046] [EC:4.6.1.1]
113093005  adenylate cyclase type 6-like [KO:K08046] [EC:4.6.1.1]
113070523  adenylate cyclase type 6-like [KO:K08046] [EC:4.6.1.1]
113065498  adenylate cyclase type 6-like [KO:K08046] [EC:4.6.1.1]
113051418  adenylate cyclase type 2-like isoform X1 [KO:K08047] [EC:4.6.1.1]
113106060  adenylate cyclase type 2-like isoform X1 [KO:K08047] [EC:4.6.1.1]
113060337  adenylate cyclase type 8-like [KO:K08048] [EC:4.6.1.1]
113092585  adenylate cyclase type 8-like isoform X1 [KO:K08048] [EC:4.6.1.1]
113120779  adenylate cyclase type 8-like isoform X1 [KO:K08048] [EC:4.6.1.1]
113120872  adenylate cyclase type 8-like [KO:K08048] [EC:4.6.1.1]
113045049  adenylate cyclase type 8-like isoform X1 [KO:K08048] [EC:4.6.1.1]
113067623  adenylate cyclase type 9-like [KO:K08049] [EC:4.6.1.1]
113051739  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
113065061  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
113039957  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
113053706  cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1 [KO:K04345] [EC:2.7.11.11]
113054947  prkacb; cAMP-dependent protein kinase catalytic subunit beta [KO:K04345] [EC:2.7.11.11]
113067676  cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
113069366  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
113097097  cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1 [KO:K04345] [EC:2.7.11.11]
113051365  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
113046138  cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
113039766  cAMP-dependent protein kinase catalytic subunit beta-like isoform X1 [KO:K04345] [EC:2.7.11.11]
113050852  5-hydroxytryptamine receptor 2A-like [KO:K04157]
113109360  5-hydroxytryptamine receptor 2A-like [KO:K04157]
113038283  5-hydroxytryptamine receptor 2A-like [KO:K04157]
113063909  5-hydroxytryptamine receptor 2C-like [KO:K04157]
113052143  5-hydroxytryptamine receptor 2C-like [KO:K04157]
113088275  5-hydroxytryptamine receptor 2A-like [KO:K04157]
113039778  5-hydroxytryptamine receptor 2B-like [KO:K04157]
113065184  5-hydroxytryptamine receptor 2B-like [KO:K04157]
113105731  5-hydroxytryptamine receptor 2C-like [KO:K04157]
113053260  5-hydroxytryptamine receptor 2A-like [KO:K04157]
113060871  metabotropic glutamate receptor 1-like isoform X1 [KO:K04603]
113120775  metabotropic glutamate receptor 1-like isoform X1 [KO:K04603]
113120926  metabotropic glutamate receptor 1-like isoform X1 [KO:K04603]
113063098  metabotropic glutamate receptor 1-like isoform X1 [KO:K04603]
113117609  metabotropic glutamate receptor 1-like isoform X1 [KO:K04603]
113117709  metabotropic glutamate receptor 1-like isoform X1 [KO:K04603]
113114713  metabotropic glutamate receptor 5-like [KO:K04604]
113109861  metabotropic glutamate receptor 5-like isoform X1 [KO:K04604]
113071626  metabotropic glutamate receptor 5-like [KO:K04604]
113058768  LOW QUALITY PROTEIN: metabotropic glutamate receptor 5-like [KO:K04604]
113112706  guanine nucleotide-binding protein G(q) subunit alpha-like [KO:K04635]
113113987  guanine nucleotide-binding protein G(q) subunit alpha-like [KO:K04635]
113079298  guanine nucleotide-binding protein subunit alpha-11-like [KO:K04635]
113082387  guanine nucleotide-binding protein subunit alpha-11-like [KO:K04635]
113040036  guanine nucleotide-binding protein subunit alpha-11-like isoform X1 [KO:K04635]
113064999  guanine nucleotide-binding protein G(q) subunit alpha-like isoform X1 [KO:K04634]
113049838  guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
113083927  guanine nucleotide-binding protein G(q) subunit alpha-like [KO:K04634]
113106612  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
113094095  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
113068500  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like isoform X1 [KO:K05858] [EC:3.1.4.11]
113068501  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
113068549  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
113068550  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like isoform X1 [KO:K05858] [EC:3.1.4.11]
113079052  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like [KO:K05858] [EC:3.1.4.11]
113083303  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like [KO:K05858] [EC:3.1.4.11]
113087941  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like isoform X1 [KO:K05858] [EC:3.1.4.11]
113117759  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like [KO:K05858] [EC:3.1.4.11]
113055353  inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
113094567  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
113050374  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
113110915  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
113061517  inositol 1,4,5-trisphosphate receptor type 2-like [KO:K04959]
113118284  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
113107211  inositol 1,4,5-trisphosphate receptor type 3-like isoform X1 [KO:K04960]
113069945  inositol 1,4,5-trisphosphate receptor type 3-like isoform X1 [KO:K04960]
113049910  protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
113097507  protein kinase C alpha type-like [KO:K02677] [EC:2.7.11.13]
113047101  protein kinase C alpha type-like isoform X1 [KO:K02677] [EC:2.7.11.13]
113053289  protein kinase C alpha type-like isoform X1 [KO:K02677] [EC:2.7.11.13]
113047295  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
113093357  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
113079629  protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
113044532  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
113070457  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
113044866  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
113116357  protein kinase C gamma type-like [KO:K19663] [EC:2.7.11.13]
113059935  protein kinase C alpha type-like isoform X1 [KO:K19663] [EC:2.7.11.13]
113108035  guanylate cyclase soluble subunit alpha-1-like [KO:K12318] [EC:4.6.1.2]
113114696  guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
113044454  guanylate cyclase soluble subunit alpha-1-like [KO:K12318] [EC:4.6.1.2]
113081255  guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
113058874  guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
113105085  guanylate cyclase soluble subunit alpha-1-like [KO:K12318] [EC:4.6.1.2]
113108046  guanylate cyclase soluble subunit beta-1-like [KO:K12319] [EC:4.6.1.2]
113108515  guanylate cyclase soluble subunit beta-1-like [KO:K12319] [EC:4.6.1.2]
113115402  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
113044452  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
113110595  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
113056342  cGMP-dependent protein kinase 1-like isoform X1 [KO:K07376] [EC:2.7.11.12]
113111947  cGMP-dependent protein kinase 1 isoform X1 [KO:K07376] [EC:2.7.11.12]
113112406  cGMP-dependent protein kinase 1-like isoform X1 [KO:K07376] [EC:2.7.11.12]
113112450  cGMP-dependent protein kinase 1-like isoform X1 [KO:K07376] [EC:2.7.11.12]
113049125  cGMP-dependent protein kinase 2-like [KO:K19477] [EC:2.7.11.12]
113077808  cGMP-dependent protein kinase 2-like [KO:K19477] [EC:2.7.11.12]
113057217  cGMP-dependent protein kinase 2-like isoform X1 [KO:K19477] [EC:2.7.11.12]
113063503  cGMP-dependent protein kinase 1-like isoform X1 [KO:K19477] [EC:2.7.11.12]
Compound
C00025  L-Glutamate
C00076  Calcium cation
C00165  Diacylglycerol
C00533  Nitric oxide
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00681  1-Acyl-sn-glycerol 3-phosphate
C00780  Serotonin
C00942  3',5'-Cyclic GMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
C03758  Dopamine
Reference
PMID:14506308
  Authors
Saez JC, Berthoud VM, Branes MC, Martinez AD, Beyer EC.
  Title
Plasma membrane channels formed by connexins: their regulation and functions.
  Journal
Physiol Rev 83:1359-400 (2003)
DOI:10.1152/physrev.00007.2003
Reference
PMID:15033580
  Authors
Warn-Cramer BJ, Lau AF.
  Title
Regulation of gap junctions by tyrosine protein kinases.
  Journal
Biochim Biophys Acta 1662:81-95 (2004)
DOI:10.1016/j.bbamem.2003.10.018
Reference
PMID:9535909
  Authors
Warn-Cramer BJ, Cottrell GT, Burt JM, Lau AF.
  Title
Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase.
  Journal
J Biol Chem 273:9188-96 (1998)
DOI:10.1074/jbc.273.15.9188
Reference
PMID:10751659
  Authors
Roerig B, Feller MB.
  Title
Neurotransmitters and gap junctions in developing neural circuits.
  Journal
Brain Res Brain Res Rev 32:86-114 (2000)
DOI:10.1016/S0165-0173(99)00069-7
Reference
PMID:10873290
  Authors
Hatton GI.
  Title
Synaptic modulation of neuronal coupling.
  Journal
Cell Biol Int 22:765-80 (1998)
DOI:10.1006/cbir.1998.0386
Reference
PMID:12566218
  Authors
Cruciani V, Mikalsen SO.
  Title
Connexins, gap junctional intercellular communication and kinases.
  Journal
Biol Cell 94:433-43 (2002)
DOI:10.1016/S0248-4900(02)00014-X
Reference
PMID:15094344
  Authors
Giepmans BN.
  Title
Gap junctions and connexin-interacting proteins.
  Journal
Cardiovasc Res 62:233-45 (2004)
DOI:10.1016/j.cardiores.2003.12.009
Reference
PMID:15955302
  Authors
Laird DW.
  Title
Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation.
  Journal
Biochim Biophys Acta 1711:172-82 (2005)
DOI:10.1016/j.bbamem.2004.09.009
Reference
PMID:15033579
  Authors
Peracchia C.
  Title
Chemical gating of gap junction channels; roles of calcium, pH and calmodulin.
  Journal
Biochim Biophys Acta 1662:61-80 (2004)
DOI:10.1016/j.bbamem.2003.10.020
Reference
PMID:15033578
  Authors
Bukauskas FF, Verselis VK.
  Title
Gap junction channel gating.
  Journal
Biochim Biophys Acta 1662:42-60 (2004)
DOI:10.1016/j.bbamem.2004.01.008
Related
pathway
caua04010  MAPK signaling pathway
caua04020  Calcium signaling pathway
caua04060  Cytokine-cytokine receptor interaction
caua04070  Phosphatidylinositol signaling system
caua04080  Neuroactive ligand-receptor interaction
KO pathway
ko04540   
LinkDB

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