KEGG   PATHWAY: gae00230
Entry
gae00230                    Pathway                                
Name
Purine metabolism - Gigantopelta aegis (peltospirid snail)
Class
Metabolism; Nucleotide metabolism
Pathway map
gae00230  Purine metabolism
gae00230

Module
gae_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:gae00230]
gae_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:gae00230]
gae_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:gae00230]
gae_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:gae00230]
gae_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:gae00230]
Other DBs
GO: 0006163 0042278
Organism
Gigantopelta aegis (peltospirid snail) [GN:gae]
Gene
121369021  ADP-ribose pyrophosphatase, mitochondrial-like isoform X1 [KO:K13988] [EC:3.6.1.13]
121375974  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
121390067  ADP-sugar pyrophosphatase-like [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
121375851  phosphoglucomutase-1-like [KO:K01835] [EC:5.4.2.2]
121376392  phosphoglucomutase-2-like [KO:K15779] [EC:5.4.2.2 5.4.2.7]
121374878  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
121375334  amidophosphoribosyltransferase-like [KO:K00764] [EC:2.4.2.14]
121390076  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
121375352  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
121375145  multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
121378271  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
121391180  LOW QUALITY PROTEIN: adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
121385470  bifunctional purine biosynthesis protein ATIC-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
121388653  adenine phosphoribosyltransferase-like [KO:K00759] [EC:2.4.2.7]
121389456  mannosylglucosyl-3-phosphoglycerate phosphatase-like [KO:K01081] [EC:3.1.3.5]
121382798  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
121383188  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
121370821  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
121370834  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
121370839  5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
121389460  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
121390884  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
121371108  purine nucleoside phosphorylase-like isoform X1 [KO:K03783] [EC:2.4.2.1]
121387158  LOW QUALITY PROTEIN: purine nucleoside phosphorylase LACC1-like [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
121387167  purine nucleoside phosphorylase LACC1-like [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
121381356  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
121369261  inosine-5'-monophosphate dehydrogenase 1-like [KO:K00088] [EC:1.1.1.205]
121371060  nucleoside diphosphate kinase 7-like isoform X1 [KO:K00940] [EC:2.7.4.6]
121374142  nucleoside diphosphate kinase-like isoform X1 [KO:K00940] [EC:2.7.4.6]
121383264  nucleoside diphosphate kinase 6-like isoform X1 [KO:K00940] [EC:2.7.4.6]
121370461  adenylate kinase 9-like isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
121384607  ectonucleoside triphosphate diphosphohydrolase 2-like [KO:K01510] [EC:3.6.1.5]
121366368  LOW QUALITY PROTEIN: soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
121378913  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
121369433  U8 snoRNA-decapping enzyme-like [KO:K16855] [EC:3.6.1.62 3.6.1.64]
121375311  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
121370649  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121379110  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121371427  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121371431  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121371433  xanthine dehydrogenase/oxidase-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121381254  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121377048  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]-like [KO:K01518] [EC:3.6.1.17]
121368762  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]-like [KO:K01518] [EC:3.6.1.17]
121391491  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]-like isoform X1 [KO:K01518] [EC:3.6.1.17]
121390051  GMP synthase [glutamine-hydrolyzing]-like isoform X1 [KO:K01951] [EC:6.3.5.2]
121388911  GMP reductase 1-like [KO:K00364] [EC:1.7.1.7]
121390881  LOW QUALITY PROTEIN: GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
121387252  guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
121375403  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
121377671  5'-deoxynucleotidase HDDC2-like [KO:K07023] [EC:3.1.3.89]
121373792  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
121380643  adenylate cyclase type 1-like isoform X1 [KO:K08041] [EC:4.6.1.1]
121388686  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
121388074  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
121381879  adenylate cyclase type 5-like [KO:K08045] [EC:4.6.1.1]
121375216  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
121373977  guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
121375967  guanylate cyclase soluble subunit beta-1-like [KO:K12319] [EC:4.6.1.2]
121368062  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
121368650  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
121391123  guanylate cyclase soluble subunit beta-1-like [KO:K12319] [EC:4.6.1.2]
121376777  atrial natriuretic peptide receptor 2-like [KO:K12321] [EC:4.6.1.2]
121389236  atrial natriuretic peptide receptor 1-like [KO:K12321] [EC:4.6.1.2]
121368083  LOW QUALITY PROTEIN: retinal guanylyl cyclase 2-like [KO:K12322] [EC:4.6.1.2]
121385054  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121385055  atrial natriuretic peptide receptor 2-like [KO:K12323] [EC:4.6.1.2]
121385057  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121377205  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121385489  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121385491  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121369120  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
121377818  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121389485  receptor-type guanylate cyclase gcy-12-like [KO:K12323] [EC:4.6.1.2]
121381239  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121381508  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121373277  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121373382  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121373605  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121373655  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121373841  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121381597  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121381599  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121382651  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
121368659  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
121381601  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
121382143  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
121374438  atrial natriuretic peptide receptor 1-like [KO:K12324] [EC:4.6.1.2]
121380950  soluble guanylate cyclase 88E-like [KO:K01769] [EC:4.6.1.2]
121381713  soluble guanylate cyclase gcy-31-like [KO:K01769] [EC:4.6.1.2]
121387039  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
121391315  LOW QUALITY PROTEIN: cGMP-dependent 3',5'-cyclic phosphodiesterase-like [KO:K18283] [EC:3.1.4.17]
121374133  cGMP-dependent 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K18283] [EC:3.1.4.17]
121370224  cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like [KO:K19021] [EC:3.1.4.17]
121379077  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like [KO:K13762] [EC:3.1.4.35]
121390589  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like [KO:K13758]
121383133  cGMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13763] [EC:3.1.4.35]
121390670  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [KO:K13761] [EC:3.1.4.35]
121375332  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121387961  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121377097  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121377098  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121388979  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121389106  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121389110  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121389111  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121385328  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
121381887  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
121371454  adenylosuccinate synthetase isozyme 1 B-like [KO:K01939] [EC:6.3.4.4]
121392448  LOW QUALITY PROTEIN: AMP deaminase 2-like [KO:K01490] [EC:3.5.4.6]
121386306  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
121384997  adenosine kinase-like [KO:K00856] [EC:2.7.1.20]
121380161  adenosine kinase-like isoform X1 [KO:K00856] [EC:2.7.1.20]
121377488  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
121377942  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
121386727  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
121385981  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
121381005  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
121383406  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
121377492  adenylate kinase-like [KO:K00939] [EC:2.7.4.3]
121392588  LOW QUALITY PROTEIN: adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
121371494  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
121378329  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
121374206  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
121370953  cancer-related nucleoside-triphosphatase-like [KO:K06928] [EC:3.6.1.15]
121374835  cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like [KO:K13293] [EC:3.1.4.53]
121375941  high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A-like isoform X1 [KO:K18436] [EC:3.1.4.53]
121383527  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like isoform X1 [KO:K18437] [EC:3.1.4.53]
121392221  LOW QUALITY PROTEIN: bis(5'-adenosyl)-triphosphatase-like [KO:K01522] [EC:3.6.1.29]
121380177  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
121375201  transthyretin-like [KO:K07127] [EC:3.5.2.17]
121390622  urease subunit alpha-like [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
gae00030  Pentose phosphate pathway
gae00220  Arginine biosynthesis
gae00250  Alanine, aspartate and glutamate metabolism
gae00260  Glycine, serine and threonine metabolism
gae00340  Histidine metabolism
gae00630  Glyoxylate and dicarboxylate metabolism
gae00730  Thiamine metabolism
gae00740  Riboflavin metabolism
gae00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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