KEGG   PATHWAY: lrj00230
Entry
lrj00230                    Pathway                                
Name
Purine metabolism - Lethenteron reissneri (Far Eastern brook lamprey)
Class
Metabolism; Nucleotide metabolism
Pathway map
lrj00230  Purine metabolism
lrj00230

Module
lrj_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:lrj00230]
lrj_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:lrj00230]
lrj_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:lrj00230]
Other DBs
GO: 0006163 0042278
Organism
Lethenteron reissneri (Far Eastern brook lamprey) [GN:lrj]
Gene
133348973  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
133349489  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
133358720  uncharacterized protein LOC133358720 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
133358840  uncharacterized protein LOC133358840 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
133349268  PGM1; phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
133343019  PGM2; phosphopentomutase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
133343053  PPAT; amidophosphoribosyltransferase isoform X1 [KO:K00764] [EC:2.4.2.14]
133357683  PFAS; LOW QUALITY PROTEIN: phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
133343052  PAICS; bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
133348016  ADSL; LOW QUALITY PROTEIN: adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
133349631  ATIC; bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
133340146  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
133345517  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
133347196  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
133341508  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
133343363  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
133339556  purine nucleoside phosphorylase-like isoform X1 [KO:K03783] [EC:2.4.2.1]
133363038  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
133363058  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
133353799  LACC1; purine nucleoside phosphorylase LACC1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
133358389  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
133358390  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
133351571  inosine-5'-monophosphate dehydrogenase 1-like isoform X1 [KO:K00088] [EC:1.1.1.205]
133355437  inosine-5'-monophosphate dehydrogenase 1b [KO:K00088] [EC:1.1.1.205]
133351534  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
133339161  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
133339162  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
133340076  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
133340978  nucleoside diphosphate kinase A 2-like [KO:K00940] [EC:2.7.4.6]
133346178  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
133345504  ectonucleoside triphosphate diphosphohydrolase 8-like isoform X1 [KO:K01510] [EC:3.6.1.5]
133343349  ectonucleoside triphosphate diphosphohydrolase 2-like [KO:K01510] [EC:3.6.1.5]
133345446  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
133347133  ENTPD5; nucleoside diphosphate phosphatase ENTPD5 [KO:K01511] [EC:3.6.1.6]
133341217  LOW QUALITY PROTEIN: xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
133341225  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
133355247  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
133350682  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
133351041  GMPS; GMP synthase [glutamine-hydrolyzing] isoform X1 [KO:K01951] [EC:6.3.5.2]
133350879  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
133340135  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
133346024  guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
133349711  GUK1; guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
133352951  ribonucleoside-diphosphate reductase subunit M2 B-like isoform X1 [KO:K10808] [EC:1.17.4.1]
133341832  HDDC2; 5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
133354381  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
133341806  deoxycytidine kinase 2-like isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
133346799  PRUNE1; exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
133344717  adenylate cyclase type 1-like isoform X1 [KO:K08041] [EC:4.6.1.1]
133345152  adenylate cyclase type 1-like isoform X1 [KO:K08041] [EC:4.6.1.1]
133350806  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
133340218  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
133344528  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
133353274  LOW QUALITY PROTEIN: adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
133349742  LOW QUALITY PROTEIN: adenylate cyclase type 5-like [KO:K08045] [EC:4.6.1.1]
133349154  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
133340728  ADCY9; LOW QUALITY PROTEIN: adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
133350055  LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
133357539  LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
133357690  GUCY1B1; guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
133340989  guanylyl cyclase C-like isoform X1 [KO:K12320] [EC:4.6.1.2]
133347587  LOW QUALITY PROTEIN: guanylyl cyclase C-like [KO:K12320] [EC:4.6.1.2]
133340790  retinal guanylyl cyclase 1-like isoform X1 [KO:K12322] [EC:4.6.1.2]
133353813  retinal guanylyl cyclase 1-like [KO:K12322] [EC:4.6.1.2]
133341892  retinal guanylyl cyclase 1-like [KO:K12322] [EC:4.6.1.2]
133350607  guanylate cyclase 2G-like isoform X1 [KO:K22600] [EC:4.6.1.2]
133343711  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
133346447  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
133339701  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
133339705  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
133355005  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
133355253  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
133350435  atrial natriuretic peptide receptor 2-like isoform X1 [KO:K12324] [EC:4.6.1.2]
133344663  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
133345236  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
133345902  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
133342957  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
133360384  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A-like [KO:K19021] [EC:3.1.4.17]
133350744  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
133345593  cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'-like [KO:K13757] [EC:3.1.4.35]
133352330  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
133358750  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma-like [KO:K13759]
133340677  retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma-like [KO:K13760]
133352414  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [KO:K13761] [EC:3.1.4.35]
133347790  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
133352445  PDE10A; LOW QUALITY PROTEIN: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
133344954  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
133347064  adenylosuccinate synthetase isozyme 2-like [KO:K01939] [EC:6.3.4.4]
133347066  adenylosuccinate synthetase isozyme 2-like [KO:K01939] [EC:6.3.4.4]
133351531  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
133348829  AMP deaminase 3-like [KO:K01490] [EC:3.5.4.6]
133349572  AMPD2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
133340870  ADA; LOW QUALITY PROTEIN: adenosine deaminase [KO:K01488] [EC:3.5.4.4]
133360378  ADA2; LOW QUALITY PROTEIN: adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
133345011  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
133360160  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
133360161  LOW QUALITY PROTEIN: adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
133353192  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
133347282  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
133341701  AK1; adenylate kinase isoenzyme 1 isoform X1 [KO:K00939] [EC:2.7.4.3]
133354675  adenylate kinase isoenzyme 5-like isoform X1 [KO:K00939] [EC:2.7.4.3]
133346623  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
133350139  GTP:AMP phosphotransferase AK3, mitochondrial-like isoform X1 [KO:K00944] [EC:2.7.4.10]
133343350  ectonucleoside triphosphate diphosphohydrolase 2-like [KO:K01509] [EC:3.6.1.-]
133341269  NTPCR; LOW QUALITY PROTEIN: cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
133347668  venom phosphodiesterase CdcPDE-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
133351955  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [KO:K13293] [EC:3.1.4.53]
133348822  cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform X1 [KO:K13293] [EC:3.1.4.53]
133355593  cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X1 [KO:K13293] [EC:3.1.4.53]
133353041  high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A-like isoform X1 [KO:K18436] [EC:3.1.4.53]
133346801  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
133346802  LOW QUALITY PROTEIN: high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like [KO:K18437] [EC:3.1.4.53]
133338953  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like [KO:K18437] [EC:3.1.4.53]
133342732  FHIT; bis(5'-adenosyl)-triphosphatase isoform X1 [KO:K01522] [EC:3.6.1.29]
133359479  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
133359668  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
133356464  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
lrj00030  Pentose phosphate pathway
lrj00220  Arginine biosynthesis
lrj00250  Alanine, aspartate and glutamate metabolism
lrj00260  Glycine, serine and threonine metabolism
lrj00340  Histidine metabolism
lrj00630  Glyoxylate and dicarboxylate metabolism
lrj00730  Thiamine metabolism
lrj00740  Riboflavin metabolism
lrj00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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