KEGG   PATHWAY: pguu00230
Entry
pguu00230                   Pathway                                
Name
Purine metabolism - Pterocles gutturalis (yellow-throated sandgrouse)
Class
Metabolism; Nucleotide metabolism
Pathway map
pguu00230  Purine metabolism
pguu00230

Module
pguu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pguu00230]
pguu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pguu00230]
pguu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pguu00230]
pguu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pguu00230]
pguu_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pguu00230]
pguu_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pguu00230]
Other DBs
GO: 0006163 0042278
Organism
Pterocles gutturalis (yellow-throated sandgrouse) [GN:pguu]
Gene
104458931  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104458571  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
104464780  NUDT5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104466525  PGM1; LOW QUALITY PROTEIN: phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104464950  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104460188  ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
104459758  LOW QUALITY PROTEIN: ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
104458614  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104468469  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104468477  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104463756  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104458398  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104466275  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104457754  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104461894  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104463223  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104461021  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
104469185  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
104470457  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104458120  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
104470937  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104471542  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104465437  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104467769  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104460652  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104469612  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104465738  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
104459787  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
104459778  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104467095  nucleoside diphosphate kinase-like isoform X1 [KO:K00940] [EC:2.7.4.6]
104458032  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
104460577  adenylate kinase 9-like [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104461098  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
104461393  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104463945  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
104470711  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104470712  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104466985  CANT1; LOW QUALITY PROTEIN: soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
104459881  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
104468869  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
104457549  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104461112  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104457804  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104470259  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104458792  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
104470689  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
104458079  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104461824  ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104468709  LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2-like [KO:K10808] [EC:1.17.4.1]
104458736  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104469319  DGUOK; deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
104459189  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104459414  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104469426  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
104469219  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
104461391  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
104464269  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104462066  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104462541  GUCY1A3; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
104468227  GUCY1B3; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
104466101  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104457980  GUCY2C; LOW QUALITY PROTEIN: heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104461772  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
104471925  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104468189  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like [KO:K13755] [EC:3.1.4.17]
104465410  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
104466109  PDE3B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104468012  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13762] [EC:3.1.4.35]
104470370  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104459964  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104460793  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104467748  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
104464625  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104462462  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104466513  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
104470720  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104461989  AMPD3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
104462149  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104461893  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104469491  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104459831  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
104461408  adenylate kinase 4, mitochondrial-like [KO:K00939] [EC:2.7.4.3]
104471324  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
104468103  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104469267  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
104472419  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104458057  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104471615  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
104467881  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104462832  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104472345  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104466905  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
104470048  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
104470195  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
104463668  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A-like isoform X1 [KO:K18437] [EC:3.1.4.53]
104471838  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
104459705  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
104461141  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104463746  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104459978  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pguu00030  Pentose phosphate pathway
pguu00220  Arginine biosynthesis
pguu00250  Alanine, aspartate and glutamate metabolism
pguu00260  Glycine, serine and threonine metabolism
pguu00340  Histidine metabolism
pguu00630  Glyoxylate and dicarboxylate metabolism
pguu00730  Thiamine metabolism
pguu00740  Riboflavin metabolism
pguu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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