Entry Name ABC transporters - Ruegeria sp. TM1040
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Ruegeria sp. TM1040 [GN:
sit ]
Gene TM1040_3032 sulfate/tungstate uptake family ABC transporter periplasmic substrate-binding protein [KO:K05772 ]
TM1040_3765 binding-protein-dependent transport systems inner membrane component [KO:K05773 ]
TM1040_3658 binding-protein-dependent transport systems inner membrane component [KO:K15599 ]
TM1040_3664 molybdenum ABC transporter periplasmic molybdate-binding protein [KO:K02020 ]
TM1040_2735 putative iron(III) transport system substrate-binding protein [KO:K02012 ]
TM1040_0543 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
TM1040_0122 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
TM1040_2817 binding-protein-dependent transport systems inner membrane component [KO:K02063 ]
TM1040_3638 binding-protein-dependent transport systems inner membrane component [KO:K11070 ]
TM1040_0325 binding-protein-dependent transport systems inner membrane component [KO:K11070 ]
TM1040_0837 binding-protein-dependent transport systems inner membrane component [KO:K11071 ]
TM1040_0324 binding-protein-dependent transport systems inner membrane component [KO:K11071 ]
TM1040_3637 binding-protein-dependent transport systems inner membrane component [KO:K11071 ]
TM1040_2981 binding-protein-dependent transport systems inner membrane component [KO:K11074 ]
TM1040_2982 binding-protein-dependent transport systems inner membrane component [KO:K11075 ]
TM1040_3154 binding-protein-dependent transport systems inner membrane component [KO:K10118 ]
TM1040_3155 binding-protein-dependent transport systems inner membrane component [KO:K10119 ]
TM1040_0430 binding-protein-dependent transport systems inner membrane component [KO:K10228 ]
TM1040_0429 binding-protein-dependent transport systems inner membrane component [KO:K10229 ]
TM1040_3306 binding-protein-dependent transport systems inner membrane component [KO:K10233 ]
TM1040_3305 binding-protein-dependent transport systems inner membrane component [KO:K10234 ]
TM1040_2419 binding-protein-dependent transport systems inner membrane component [KO:K17322 ]
TM1040_2420 binding-protein-dependent transport systems inner membrane component [KO:K17323 ]
TM1040_0850 binding-protein-dependent transport systems inner membrane component [KO:K05814 ]
TM1040_3215 binding-protein-dependent transport systems inner membrane component [KO:K05814 ]
TM1040_0851 binding-protein-dependent transport systems inner membrane component [KO:K05815 ]
TM1040_3214 binding-protein-dependent transport systems inner membrane component [KO:K05815 ]
TM1040_1262 phosphate ABC transporter periplasmic phosphate-binding protein [KO:K02040 ]
TM1040_0295 Amino acid ABC transporter permease protein 3-TM region His/Glu/Gln/Arg/opine [KO:K09970 ]
TM1040_0296 Amino acid ABC transporter permease protein 3-TM region His/Glu/Gln/Arg/opine [KO:K09971 ]
TM1040_3039 Amino acid ABC transporter permease protein 3-TM region His/Glu/Gln/Arg/opine [KO:K16962 ]
TM1040_0119 branched-chain amino acid ABC transporter periplasmic branched-chain amino acid binding protein putative [KO:K01999 ]
TM1040_2551 binding-protein-dependent transport systems inner membrane component [KO:K13894 ]
TM1040_2550 binding-protein-dependent transport systems inner membrane component [KO:K13895 ]
TM1040_1846 Lipoprotein releasing system transmembrane protein LolC/E family [KO:K09808 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
