KEGG   PATHWAY: sund04144
Entry
sund04144                   Pathway                                
Name
Endocytosis - Sceloporus undulatus (fence lizard)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
sund04144  Endocytosis
sund04144

Other DBs
GO: 0006897
Organism
Sceloporus undulatus (fence lizard) [GN:sund]
Gene
121924055  ARF6; ADP-ribosylation factor 6 [KO:K07941]
121915171  ADP-ribosylation factor 6-like [KO:K07941]
121916297  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
121920195  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
121936597  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
121936022  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
121932895  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
121925084  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
121936515  DNM1; dynamin-1 isoform X1 [KO:K01528] [EC:3.6.5.5]
121920604  LOW QUALITY PROTEIN: dynamin-2-like [KO:K23484] [EC:3.6.5.5]
121921404  CLTA; LOW QUALITY PROTEIN: clathrin light chain A [KO:K04644]
121923386  CLTB; clathrin light chain B isoform X1 [KO:K04645]
121916526  CLTCL1; clathrin heavy chain 2 isoform X1 [KO:K04646]
121916873  CLTC; clathrin heavy chain 1 isoform X1 [KO:K04646]
121916136  AP2A2; AP-2 complex subunit alpha-2 isoform X1 [KO:K11824]
121933265  AP2A1; AP-2 complex subunit alpha-1 isoform X1 [KO:K11824]
121917030  AP2B1; AP-2 complex subunit beta isoform X1 [KO:K11825]
121925420  AP2M1; AP-2 complex subunit mu isoform X1 [KO:K11826]
121916043  AP2S1; AP-2 complex subunit sigma isoform X1 [KO:K11827]
121917532  EH domain-containing protein 2-like [KO:K12469]
121917584  EH domain-containing protein 2-like [KO:K12469]
121934210  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
121934614  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
121928986  ZFYVE9; zinc finger FYVE domain-containing protein 9 [KO:K04679]
121921480  ZFYVE16; zinc finger FYVE domain-containing protein 16 [KO:K04679]
121932865  uncharacterized protein LOC121932865 isoform X1 [KO:K10054] [EC:2.3.2.-]
121932867  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
121921670  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
121934446  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
121925338  TFRC; transferrin receptor protein 1 isoform X1 [KO:K06503]
121935547  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
121930753  PDGFRA; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
121925296  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
121925139  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
121922397  FGFR4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
121933049  IGF1R; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
121916237  CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1 [KO:K04707] [EC:2.3.2.27]
121934432  CBL; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
121917208  E3 ubiquitin-protein ligase CBL-B-like isoform X1 [KO:K22517] [EC:2.3.2.27]
121917254  E3 ubiquitin-protein ligase CBL-B-like isoform X1 [KO:K22517] [EC:2.3.2.27]
121926098  SH3KBP1; LOW QUALITY PROTEIN: SH3 domain-containing kinase-binding protein 1 [KO:K12470]
121924139  SH3GL2; endophilin-A1 [KO:K11247]
121934684  SH3GL3; endophilin-A3 isoform X1 [KO:K11247]
121936426  SH3GL1; endophilin-A2 isoform X1 [KO:K11247]
121928117  SH3GLB1; endophilin-B1 isoform X1 [KO:K11248]
121937397  SH3GLB2; LOW QUALITY PROTEIN: endophilin-B2 [KO:K21269]
121922525  BIN1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
121933606  AMPH; amphiphysin [KO:K12562]
121933374  EPN1; epsin-1 isoform X1 [KO:K12471]
121922880  EPN3; epsin-3 isoform X1 [KO:K12471]
121914828  EPN2; epsin-2 isoform X1 [KO:K12471]
121928304  EPS15; epidermal growth factor receptor substrate 15 isoform X1 [KO:K12472]
121917704  epidermal growth factor receptor substrate 15-like 1 [KO:K12472]
121926253  SPART; spartin isoform X1 [KO:K19366]
121933218  NEDD4; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase NEDD4 [KO:K10591] [EC:2.3.2.26]
121920943  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
121930774  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
121929536  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
121922226  RNF41; E3 ubiquitin-protein ligase NRDP1 [KO:K11981] [EC:2.3.2.27]
121929870  ITCH; E3 ubiquitin-protein ligase Itchy homolog [KO:K05632] [EC:2.3.2.26]
121914426  SMURF1; E3 ubiquitin-protein ligase SMURF1 [KO:K04678] [EC:2.3.2.26]
121921541  SMURF2; E3 ubiquitin-protein ligase SMURF2 [KO:K04678] [EC:2.3.2.26]
121928360  WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
121920600  LDLR; LOW QUALITY PROTEIN: low-density lipoprotein receptor [KO:K12473]
121919980  low density lipoprotein receptor adapter protein 1-like isoform X1 [KO:K12474]
121915444  LDLRAP1; low density lipoprotein receptor adapter protein 1 isoform X1 [KO:K12474]
121923195  DAB2; disabled homolog 2 isoform X1 [KO:K12475]
121932494  C-C chemokine receptor type 5-like [KO:K04180]
121935152  C-C chemokine receptor type 5-like isoform X1 [KO:K04180]
121919133  C-X-C chemokine receptor type 1-like [KO:K05050]
121931002  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
121933941  GRK1; rhodopsin kinase GRK1 [KO:K00909] [EC:2.7.11.14]
121926933  GRK7; rhodopsin kinase GRK7 [KO:K00909] [EC:2.7.11.14]
121923548  GRK2; beta-adrenergic receptor kinase 1 [KO:K00910] [EC:2.7.11.15]
121922400  GRK6; G protein-coupled receptor kinase 6 isoform X1 [KO:K08291] [EC:2.7.11.16]
121933491  G protein-coupled receptor kinase 5-like [KO:K08291] [EC:2.7.11.16]
121926079  GRK5; G protein-coupled receptor kinase 5 isoform X1 [KO:K08291] [EC:2.7.11.16]
121933962  LOW QUALITY PROTEIN: beta-arrestin-2-like [KO:K04439]
121926420  ARRB1; beta-arrestin-1 isoform X1 [KO:K04439]
121930685  WASL; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
121920661  ACTR2; actin-related protein 2 [KO:K17260]
121915830  actin-related protein 2-like [KO:K17260]
121929023  ACTR3; actin-related protein 3 isoform X1 [KO:K18584]
121934914  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
121914193  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
121914866  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
121934554  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
121916565  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
121921214  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
121918561  actin-related protein 2/3 complex subunit 5-like [KO:K05754]
121929561  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
121936035  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
121932650  WIPF3; WAS/WASL-interacting protein family member 3 isoform X1 [KO:K19475]
121933346  WIPF1; WAS/WASL-interacting protein family member 1 [KO:K19475]
121935228  WIPF2; WAS/WASL-interacting protein family member 2 [KO:K19475]
121916295  LOW QUALITY PROTEIN: heat shock 70 kDa protein-like [KO:K03283]
121916296  heat shock 70 kDa protein-like [KO:K03283]
121933069  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
121915091  heat shock cognate 71 kDa protein-like isoform X1 [KO:K03283]
121928699  DNAJC6; putative tyrosine-protein phosphatase auxilin isoform X1 [KO:K09526]
121930986  WASHC4; WASH complex subunit 4 isoform X1 [KO:K18465]
121929157  WASHC5; LOW QUALITY PROTEIN: WASH complex subunit 5 [KO:K18464]
121925862  WASH complex subunit 2-like [KO:K18462]
121930988  WASHC1; WASH complex subunit 1 isoform X1 [KO:K18461]
121931285  WASHC3; WASH complex subunit 3 [KO:K18463]
121928868  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
121934044  F-actin-capping protein subunit alpha-2-like [KO:K10364]
121930496  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
121931338  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
121936145  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
121916569  vacuolar protein sorting-associated protein 29-like [KO:K18467]
121916752  VPS29; vacuolar protein sorting-associated protein 29 isoform X1 [KO:K18467]
121935799  VPS26B; vacuolar protein sorting-associated protein 26B [KO:K18466]
121925786  VPS26A; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 26A [KO:K18466]
121914149  VPS35; vacuolar protein sorting-associated protein 35 [KO:K18468]
121918150  SNX3; sorting nexin-3 isoform X1 [KO:K17918]
121936789  SNX12; sorting nexin-12 [KO:K17918]
121934289  USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1 [KO:K11839] [EC:3.4.19.12]
121932416  STAM-binding protein [KO:K11866] [EC:3.4.19.12]
121922071  RAB7A; ras-related protein Rab-7a [KO:K07897]
121924308  ras-related protein Rab-7a-like isoform X1 [KO:K07897]
121922713  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
121934398  STAM; signal transducing adapter molecule 1 [KO:K04705]
121929642  STAM2; signal transducing adapter molecule 2 isoform X1 [KO:K04705]
121919763  TSG101; tumor susceptibility gene 101 protein isoform X1 [KO:K12183]
121921042  MVB12A; multivesicular body subunit 12A [KO:K12186]
121936806  MVB12B; multivesicular body subunit 12B isoform X1 [KO:K12186]
121928407  VPS28; vacuolar protein sorting-associated protein 28 homolog isoform X1 [KO:K12184]
121916603  VPS37B; vacuolar protein sorting-associated protein 37B [KO:K12185]
121916911  VPS37D; vacuolar protein sorting-associated protein 37D [KO:K12185]
121915220  VPS37C; vacuolar protein sorting-associated protein 37C [KO:K12185]
121932130  VPS37A; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 37A [KO:K12185]
121934083  SNF8; vacuolar-sorting protein SNF8 isoform X1 [KO:K12188]
121917097  VPS36; vacuolar protein-sorting-associated protein 36 isoform X1 [KO:K12190]
121935700  VPS25; vacuolar protein-sorting-associated protein 25 [KO:K12189]
121923426  CHMP6; charged multivesicular body protein 6 [KO:K12195]
121929442  CHMP4B; charged multivesicular body protein 4b [KO:K12194]
121930122  CHMP4C; charged multivesicular body protein 4c [KO:K24782]
121933257  CHMP2A; charged multivesicular body protein 2a [KO:K12191]
121926950  CHMP2B; charged multivesicular body protein 2b [KO:K12192]
121935052  CHMP7; charged multivesicular body protein 7 isoform X1 [KO:K15053]
121937462  VPS4A; vacuolar protein sorting-associated protein 4A [KO:K12196]
121927780  VPS4B; vacuolar protein sorting-associated protein 4B [KO:K12196]
121933524  VTA1; vacuolar protein sorting-associated protein VTA1 homolog [KO:K12199]
121914746  CHMP1A; charged multivesicular body protein 1a [KO:K12197]
121937180  CHMP1B; charged multivesicular body protein 1b [KO:K12197]
121935134  CHMP5; charged multivesicular body protein 5 [KO:K12198]
121914247  IST1; IST1 homolog isoform X1 [KO:K19476]
121933558  programmed cell death 6-interacting protein isoform X1 [KO:K12200]
121935196  SPG21; maspardin isoform X1 [KO:K19367]
121928273  IGF2R; LOW QUALITY PROTEIN: cation-independent mannose-6-phosphate receptor [KO:K06564]
121922758  SNX2; sorting nexin-2 isoform X1 [KO:K17917]
121934796  SNX1; sorting nexin-1 [KO:K17917]
121928886  SNX5; sorting nexin-5 [KO:K17920]
121937576  SNX6; sorting nexin-6 isoform X2 [KO:K17920]
121928245  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
121926328  HRAS; GTPase HRas [KO:K02833]
121931967  interleukin-2 receptor subunit alpha-like [KO:K05068]
121930375  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
121937400  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
121922392  transforming protein RhoA-like isoform X1 [KO:K04513]
121921506  RHOA; transforming protein RhoA [KO:K04513]
121922430  major histocompatibility complex class I-related gene protein-like [KO:K06751]
121923018  H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1 [KO:K06751]
121923025  major histocompatibility complex class I-related gene protein-like isoform X1 [KO:K06751]
121923203  LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein-like [KO:K06751]
121923946  major histocompatibility complex class I-related gene protein-like [KO:K06751]
121924284  major histocompatibility complex class I-related gene protein-like isoform X1 [KO:K06751]
121924285  major histocompatibility complex class I-related gene protein-like isoform X1 [KO:K06751]
121924287  H-2 class I histocompatibility antigen, Q9 alpha chain-like isoform X1 [KO:K06751]
121922877  RTBDN; retbindin isoform X1 [KO:K13649]
121928327  LOW QUALITY PROTEIN: riboflavin-binding protein-like [KO:K13649]
121931791  CAV1; caveolin-1 isoform X1 [KO:K06278]
121923089  caveolin-2-like [KO:K12958]
121932024  CAV2; caveolin-2 [KO:K12958]
121921325  caveolin-3-like [KO:K12959]
121929787  EHD3; EH domain-containing protein 3 [KO:K12476]
121919354  EHD4; EH domain-containing protein 4 [KO:K12477]
121930856  EEA1; early endosome antigen 1 isoform X1 [KO:K12478]
121934513  RAB5A; ras-related protein Rab-5A [KO:K07887]
121921421  RAB5B; ras-related protein Rab-5B [KO:K07888]
121934553  RAB5C; ras-related protein Rab-5C [KO:K07889]
121916885  RABEP1; rab GTPase-binding effector protein 1 [KO:K12480]
121922057  RBSN; rabenosyn-5 [KO:K12481]
121937363  RAB4A; ras-related protein Rab-4A isoform X1 [KO:K07879]
121922647  RUFY1; RUN and FYVE domain-containing protein 1 isoform X1 [KO:K12482]
121926400  RUFY2; RUN and FYVE domain-containing protein 2 isoform X1 [KO:K12482]
121916100  EHD1; EH domain-containing protein 1 isoform X1 [KO:K12483]
121916046  VPS45; vacuolar protein sorting-associated protein 45 [KO:K12479]
121933372  SNX4; sorting nexin-4 [KO:K17919]
121928434  RAB31; ras-related protein Rab-31 [KO:K07891]
121928815  RAB22A; ras-related protein Rab-22A [KO:K07891]
121928465  ras-related protein Rab-10-like [KO:K07903]
121924323  RAB10; ras-related protein Rab-10 [KO:K07903]
121916456  RAB35; ras-related protein Rab-35 [KO:K07876]
121932770  ras-related protein Rab-35-like [KO:K07876]
121934453  RAB11A; ras-related protein Rab-11A [KO:K07904]
121937094  RAB11B; ras-related protein Rab-11B [KO:K07905]
121922892  rab11 family-interacting protein 2-like [KO:K12484]
121934491  RAB11FIP1; rab11 family-interacting protein 1 isoform X1 [KO:K12484]
121930515  RAB11FIP5; rab11 family-interacting protein 5 [KO:K12484]
121925306  RAB11FIP2; rab11 family-interacting protein 2 isoform X1 [KO:K12484]
121926126  ZFYVE27; protrudin isoform X1 [KO:K19368]
121923378  KIF5A; kinesin heavy chain isoform X1 [KO:K10396]
121918985  KIF5C; kinesin heavy chain [KO:K10396]
121934271  KIF5B; LOW QUALITY PROTEIN: kinesin-1 heavy chain [KO:K10396]
121923317  RAB11FIP4; rab11 family-interacting protein 4 isoform X1 [KO:K12485]
121914239  RAB11FIP3; rab11 family-interacting protein 3 isoform X1 [KO:K12485]
121933097  PARD3; LOW QUALITY PROTEIN: partitioning defective 3 homolog [KO:K04237]
121928008  PARD6B; partitioning defective 6 homolog beta [KO:K06093]
121929970  PARD6G; partitioning defective 6 homolog gamma [KO:K06093]
121914965  PARD6A; partitioning defective 6 homolog alpha isoform X1 [KO:K06093]
121936709  PRKCZ; protein kinase C zeta type isoform X1 [KO:K18952] [EC:2.7.11.13]
121925748  PRKCI; LOW QUALITY PROTEIN: protein kinase C iota type [KO:K06069] [EC:2.7.11.13]
121924210  cell division control protein 42 homolog [KO:K04393]
121936654  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
121935339  SMAP1; stromal membrane-associated protein 1 isoform X1 [KO:K12486]
121915447  SMAP2; stromal membrane-associated protein 2 [KO:K12486]
121917023  GIT1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
121929749  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like [KO:K12488]
121919821  ASAP2; LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 [KO:K12488]
121930109  ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12488]
121915205  ASAP3; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12488]
121934705  ACAP1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [KO:K12489]
121924666  ACAP2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K12489]
121936796  ACAP3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12489]
121932022  ARAP2; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K18440]
121929327  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
121933022  AGAP3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 [KO:K12491]
121930650  AGAP1; LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 [KO:K12491]
121920835  AGAP2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K17848]
121928068  ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [KO:K12492]
121937537  ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
121930785  ARFGAP3; ADP-ribosylation factor GTPase-activating protein 3 isoform X1 [KO:K12493]
121932670  PH and SEC7 domain-containing protein 4-like isoform X1 [KO:K12494]
121929659  PSD2; PH and SEC7 domain-containing protein 2 [KO:K12494]
121924918  PSD; PH and SEC7 domain-containing protein 1 [KO:K12494]
121922321  PSD3; PH and SEC7 domain-containing protein 3 isoform X1 [KO:K12494]
121922689  IQSEC2; IQ motif and SEC7 domain-containing protein 2 isoform X1 [KO:K12495]
121930356  IQSEC3; IQ motif and SEC7 domain-containing protein 3 isoform X1 [KO:K12495]
121921553  IQSEC1; IQ motif and SEC7 domain-containing protein 1 isoform X1 [KO:K12495]
121922788  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
121934248  CYTH2; cytohesin-2 isoform X1 [KO:K18441]
121914303  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
121931145  CYTH4; cytohesin-4 isoform X1 [KO:K18441]
121928166  ARFGEF2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 [KO:K18442]
121929551  ARFGEF1; brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1 [KO:K18442]
121924912  GBF1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1 [KO:K18443]
121935588  ARF1; ADP-ribosylation factor 1 [KO:K07937]
121922570  ARF3; ADP-ribosylation factor 3 [KO:K07938]
121922569  ARF4; ADP-ribosylation factor 4 [KO:K07939]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
sund04060  Cytokine-cytokine receptor interaction
sund04070  Phosphatidylinositol signaling system
sund04130  SNARE interactions in vesicular transport
sund04142  Lysosome
sund04350  TGF-beta signaling pathway
KO pathway
ko04144   
LinkDB

DBGET integrated database retrieval system