KEGG   PATHWAY: zof00270
Entry
zof00270                    Pathway                                
Name
Cysteine and methionine metabolism - Zingiber officinale (ginger)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
zof00270  Cysteine and methionine metabolism
zof00270

Module
zof_M00021  Cysteine biosynthesis, serine => cysteine [PATH:zof00270]
zof_M00034  Methionine salvage pathway [PATH:zof00270]
zof_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:zof00270]
Other DBs
GO: 0006534 0006555
Organism
Zingiber officinale (ginger) [GN:zof]
Gene
122003911  probable serine acetyltransferase 3 [KO:K00640] [EC:2.3.1.30]
122025615  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
122044406  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
121976443  probable serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
122048983  probable serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
122011912  probable serine acetyltransferase 4 [KO:K00640] [EC:2.3.1.30]
122051505  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
122020959  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
121971231  probable serine acetyltransferase 2 isoform X1 [KO:K00640] [EC:2.3.1.30]
122056030  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
121988821  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2-like [KO:K01738] [EC:2.5.1.47]
122027138  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
122006615  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
122028604  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
122008220  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
122008406  bifunctional cystathionine gamma-lyase/cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
122032752  cysteine synthase [KO:K01738] [EC:2.5.1.47]
121981846  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
122051235  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
122014505  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
121985694  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
122038750  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1-like [KO:K01738] [EC:2.5.1.47]
122055848  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
122002360  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
122045512  bifunctional L-3-cyanoalanine synthase/cysteine synthase 2, mitochondrial-like [KO:K13034] [EC:2.5.1.47 4.4.1.9]
122041004  L-3-cyanoalanine synthase 2, mitochondrial-like [KO:K13034] [EC:2.5.1.47 4.4.1.9]
121974387  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
121969273  cystathionine beta-lyase, chloroplastic-like isoform X1 [KO:K01760] [EC:4.4.1.13]
122042245  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
122004974  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122026587  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122008314  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122046776  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
121994982  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122009900  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122010416  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
121999355  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
121999399  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122000965  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122054802  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122040083  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
121972336  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
121972808  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122016751  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
122016989  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
121979591  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2 [KO:K00549] [EC:2.1.1.14]
121980985  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
122012221  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2-like [KO:K00549] [EC:2.1.1.14]
121984084  uncharacterized protein LOC121984084 isoform X1 [KO:K00549] [EC:2.1.1.14]
122014768  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2-like [KO:K00549] [EC:2.1.1.14]
122037917  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2-like [KO:K00549] [EC:2.1.1.14]
121984874  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
122017508  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
121977044  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
122049041  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
122051266  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122051417  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122051421  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122012288  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122012293  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
122036337  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122036732  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122023108  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
122054195  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
121972020  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
122039562  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
122055672  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122055678  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
122055817  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
121988480  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
122017665  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
122007210  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
122008682  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121997362  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121983660  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
122038279  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
122002957  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121991916  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121993106  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121980597  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121995822  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
122010257  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
121997084  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121984508  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
122016491  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
122003540  nicotianamine synthase 9-like [KO:K05953] [EC:2.5.1.43]
122019124  nicotianamine synthase 9-like [KO:K05953] [EC:2.5.1.43]
122050754  nicotianamine synthase 9-like [KO:K05953] [EC:2.5.1.43]
122000908  nicotianamine synthase 9-like [KO:K05953] [EC:2.5.1.43]
122009319  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
122016354  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
121976165  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
122007836  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
122014793  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
121971487  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
122006903  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
121981538  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
121985415  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
122002654  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
122041634  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
122006862  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
122046160  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
122002619  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
121988896  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121975659  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
122006298  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
122030283  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121997841  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
122012770  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121999618  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121970590  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like isoform X1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
122014700  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121971608  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
122056318  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
121967377  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
122051787  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
122052588  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
122032086  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
121982140  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
122034755  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
121986016  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
122004847  aromatic aminotransferase ISS1-like isoform X1 [KO:K00837] [EC:2.6.1.-]
122042973  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
122047484  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
122009529  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
122035979  aromatic aminotransferase ISS1-like isoform X1 [KO:K00837] [EC:2.6.1.-]
122016557  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
121975136  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
121970025  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
122043251  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
122006568  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
122009683  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
122047772  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
122034073  DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
122037765  DNA (cytosine-5)-methyltransferase CMT2-like isoform X1 [KO:K00558] [EC:2.1.1.37]
122002311  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
122014979  uncharacterized protein LOC122014979 isoform X1 [KO:K17398] [EC:2.1.1.37]
122041630  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
121975285  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
122046155  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
122031914  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
122034185  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
121970203  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
122022598  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
122053642  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
122004538  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121979260  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121982705  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121983908  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121999605  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
122041734  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
121987968  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
122017199  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
121990046  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
122029076  1-aminocyclopropane-1-carboxylate synthase 1-like isoform X1 [KO:K01762] [EC:4.4.1.14]
122046257  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
121993891  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
122010864  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
122011509  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
121982647  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
121998057  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
122013506  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
121970679  1-aminocyclopropane-1-carboxylate synthase 1-like isoform X1 [KO:K01762] [EC:4.4.1.14]
122014466  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
121987634  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
122025277  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122018536  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992402  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992501  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992502  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992503  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992504  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992505  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992506  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992507  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992508  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992509  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992510  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992511  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121992512  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121995867  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122032607  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
121996350  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121996443  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121996445  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121996446  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121996447  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121996448  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122035023  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
121983045  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
122020406  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122051942  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122021399  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122022386  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122023398  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
122051362  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
122036037  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
122053324  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
122055730  aspartokinase 1, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
122018929  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
122022639  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
122020492  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
122024274  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
122043209  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
122019085  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
122019911  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
122023926  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
122046789  cystathionine gamma-synthase 1, chloroplastic-like [KO:K27857] [EC:2.5.1.160]
122002278  cystathionine gamma-synthase 1, chloroplastic-like [KO:K27857] [EC:2.5.1.160]
122006536  cystathionine gamma-synthase 1, chloroplastic-like [KO:K27857] [EC:2.5.1.160]
122042268  cystathionine gamma-synthase 1, chloroplastic-like [KO:K27857] [EC:2.5.1.160]
122041733  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
122046256  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
122047337  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
121982317  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
121986204  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
122040181  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
122003836  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121976664  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121977134  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121999202  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
122036339  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121970960  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
122000248  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
122021432  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
122019803  glutamate--cysteine ligase A, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
122023656  glutamate--cysteine ligase A, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
122020776  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
122024469  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
122012384  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
122022673  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
122016337  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
122020417  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
122024200  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
122031878  aspartate aminotransferase, chloroplastic-like isoform X1 [KO:K00811] [EC:2.6.1.1]
122034202  aspartate aminotransferase, chloroplastic-like isoform X1 [KO:K00811] [EC:2.6.1.1]
122041817  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
122006714  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
122046338  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
122002465  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
121992081  L-lactate dehydrogenase A-like [KO:K00016] [EC:1.1.1.27]
121992082  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
122007953  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
121996014  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
121996015  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
122013586  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
121975400  putative D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121990807  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
121992156  putative D-cysteine desulfhydrase 1, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121996103  putative D-cysteine desulfhydrase 1, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121970313  putative D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121970315  putative D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
122056349  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
122017527  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
122019783  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
122007934  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
122051821  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
122023459  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
122042530  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
122045438  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
121992038  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
122047045  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
121995957  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
122040932  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
122042397  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
121975345  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
121992668  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
122046908  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
121993162  malate dehydrogenase, glyoxysomal-like isoform X1 [KO:K00026] [EC:1.1.1.37]
121996628  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
122010255  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
122034122  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
121997126  malate dehydrogenase, glyoxysomal-like isoform X1 [KO:K00026] [EC:1.1.1.37]
122020348  malate dehydrogenase, glyoxysomal isoform X1 [KO:K00026] [EC:1.1.1.37]
122021156  malate dehydrogenase, mitochondrial-like isoform X1 [KO:K00026] [EC:1.1.1.37]
122022755  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
122023696  malate dehydrogenase, glyoxysomal-like isoform X1 [KO:K00026] [EC:1.1.1.37]
122016486  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
122024987  malate dehydrogenase, mitochondrial-like isoform X1 [KO:K00026] [EC:1.1.1.37]
122036554  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like isoform X1 [KO:K22846] [EC:2.5.1.144]
121972064  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like [KO:K22846] [EC:2.5.1.144]
121975848  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
122006456  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
122032076  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121982148  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
122034445  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121970753  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
122053201  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
122038156  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
122027324  phosphoserine aminotransferase 1, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
122029714  phosphoserine aminotransferase 1, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01102  O-Phospho-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
zof00010  Glycolysis / Gluconeogenesis
zof00250  Alanine, aspartate and glutamate metabolism
zof00260  Glycine, serine and threonine metabolism
zof00290  Valine, leucine and isoleucine biosynthesis
zof00430  Taurine and hypotaurine metabolism
zof00480  Glutathione metabolism
zof00620  Pyruvate metabolism
zof00640  Propanoate metabolism
zof00770  Pantothenate and CoA biosynthesis
zof00900  Terpenoid backbone biosynthesis
zof00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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