Peptidases and Inhibitors - Hipposideros armiger (great roundleaf bat)

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     KO
 Aspartic peptidases
 
 Cysteine peptidases
 
 Glutamic peptidases
 
 Metallo peptidases
 
 Asparagine peptide lyases
 
 Mixed peptidases
 
 Serine peptidases
   Family S1: chymotrypsin family
     109384817 chymotrypsinogen B
     109384818 chymotrypsinogen 2 isoform X1
     109371862 CORIN; atrial natriuretic peptide-converting enzyme isoform X1
     109377106 OVCH2; ovochymase-2
     109396814 OVCH1; ovochymase-1
     109384904 HABP2; hyaluronan-binding protein 2 isoform X1
     109376384 anionic trypsin
     109395584 trypsin
     109391711 TMPRSS15; enteropeptidase
     109374206 PRSS8; prostasin isoform X1
     109372949 PRSS12; neurotrypsin isoform X1
     109377677 testisin-like
     109377673 brain-specific serine protease 4-like
     109377674 PRSS27; serine protease 27
     109377678 serine protease 33-like
     109374173 PRSS36; polyserase-2
     109374185 PRSS53; serine protease 53 isoform X1
     109374905 CHRND; acetylcholine receptor subunit delta
     109390581 PRSS57; serine protease 57 isoform X1
     109393277 serine protease 58-like
     109395585 PRSS58; serine protease 58
     109395592 probable inactive serine protease 58
     109390590 ELANE; neutrophil elastase isoform X1
     109393625 cathepsin G-like
     109393630 cathepsin G-like
     109390589 PRTN3; myeloblastin isoform X1
     109382131 GZMA; granzyme A
     109378494 granzyme B-like
     109378533 LOW QUALITY PROTEIN: granzyme B-like
     109378535 mast cell protease 3-like
     109378555 LOW QUALITY PROTEIN: granzyme H-like
     109378558 mast cell protease 3-like
     109378669 duodenase-1-like
     109378715 duodenase-1-like
     109378716 mast cell protease 1A-like
     109393608 granzyme H-like
     109382126 GZMK; granzyme K
     109390595 GZMM; LOW QUALITY PROTEIN: granzyme M
     109393626 mast cell protease 4-like
     109393631 chymase-like
     109371421 CELA1; chymotrypsin-like elastase family member 1
     109381303 chymotrypsin-like elastase family member 2A
     109396740 CELA3B; chymotrypsin-like elastase family member 3B
     109381248 CTRC; chymotrypsin-C
     109390988 KLK1; kallikrein-1
     109395838 KLKB1; plasma kallikrein isoform X1
     109391013 KLK5; kallikrein-5
     109391009 kallikrein-6-like
     109391010 KLK7; LOW QUALITY PROTEIN: kallikrein-7
     109391034 KLK8; kallikrein-8
     109391037 KLK9; kallikrein-9
     109391020 KLK10; kallikrein-10
     109391017 KLK11; kallikrein-11 isoform X1
     109391019 KLK12; kallikrein-12
     109391035 KLK13; kallikrein-13
     109391036 KLK14; kallikrein-14
     109390989 kallikrein-15-like
     109373633 C1RL; complement C1r subcomponent-like protein isoform X1
     109371149 MASP1; mannan-binding lectin serine protease 1 isoform X1
     109381284 MASP2; mannan-binding lectin serine protease 2 isoform X1
     109373632 C1R; complement C1r subcomponent isoform X1
     109373658 C1S; complement C1s subcomponent
     109373064 CFB; complement factor B isoform X1
     109390585 CFD; complement factor D
     109379435 CFI; complement factor I
     109390173 F2; prothrombin
     109383930 F7; coagulation factor VII isoform X1
     109388665 F9; coagulation factor IX
     109383929 F10; coagulation factor X
     109389742 F12; coagulation factor XII isoform X1
     109371798 PROC; vitamin K-dependent protein C isoform X1
     109396613 ACR; acrosin
     109372038 HPN; serine protease hepsin
     109390929 HGFAC; hepatocyte growth factor activator isoform X1
     109386253 PLAT; tissue-type plasminogen activator
     109371644 PLAU; urokinase-type plasminogen activator
     109372657 TMPRSS2; transmembrane protease serine 2
     109395185 TMPRSS3; transmembrane protease serine 3 isoform X1
     109385279 TMPRSS4; transmembrane protease serine 4 isoform X1
     109394778 TMPRSS5; transmembrane protease serine 5 isoform X1
     109394513 TMPRSS6; transmembrane protease serine 6 isoform X1
     109374832 TMPRSS7; transmembrane protease serine 7
     109390599 TMPRSS9; transmembrane protease serine 9 isoform X1
     109375901 TMPRSS11A; transmembrane protease serine 11A
     109375903 transmembrane protease serine 11B-like protein
     109375908 transmembrane protease serine 11C-like
     109375904 TMPRSS11D; transmembrane protease serine 11D isoform X1
     109376187 transmembrane protease serine 11E-like
     109375902 TMPRSS11F; transmembrane protease serine 11F
     109385289 TMPRSS13; transmembrane protease serine 13
     109389601 CTRL; chymotrypsin-like protease CTRL-1 isoform X1
     109392376 ST14; suppressor of tumorigenicity 14 protein
     109390565 AZU1; LOW QUALITY PROTEIN: azurocidin
     109389132 haptoglobin
     109376002 MST1; hepatocyte growth factor-like protein isoform X1
     109382985 HTRA1; LOW QUALITY PROTEIN: serine protease HTRA1
     109371208 HTRA2; serine protease HTRA2, mitochondrial
     109372927 HTRA3; serine protease HTRA3
     109373153 HTRA4; serine protease HTRA4
     109372186 TYSND1; peroxisomal leader peptide-processing protease isoform X1
     109383280 PRSS23; serine protease 23
K01310 CTRB; chymotrypsin [EC:3.4.21.1] 
K01310 CTRB; chymotrypsin [EC:3.4.21.1] 
K09614 CORIN; atrial natriuretic peptide-converting enzyme [EC:3.4.21.-] 
K01362 OVCH; ovochymase [EC:3.4.21.-] 
K01362 OVCH; ovochymase [EC:3.4.21.-] 
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-] 
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4] 
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4] 
K01316 TMPRSS15; enterokinase [EC:3.4.21.9] 
K08664 PRSS8; prostasin [EC:3.4.21.-] 
K09624 PRSS12; neurotrypsin [EC:3.4.21.-] 
K09625 PRSS21; testisin [EC:3.4.21.-] 
K09626 PRSS22; brain-specific serine protease 4 [EC:3.4.21.-] 
K09628 PRSS27; serine protease 27 [EC:3.4.21.-] 
K09629 PRSS33; serine protease 33 [EC:3.4.21.-] 
K09630 PRSS36; polyserase 2 [EC:3.4.21.-] 
K25708 PRSS53; serine protease 53 [EC:3.4.21.-] 
K23440 PRSS56; serine protease 56 [EC:3.4.21.-] 
K23011 PRSS57; serine protease 57 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K01327 ELANE; leukocyte elastase [EC:3.4.21.37] 
K01319 CTSG; cathepsin G [EC:3.4.21.20] 
K01319 CTSG; cathepsin G [EC:3.4.21.20] 
K01350 PRTN3; myeloblastin [EC:3.4.21.76] 
K01352 GZMA; granzyme A [EC:3.4.21.78] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K09616 GZMH; granzyme H (cathepsin G-like 2) [EC:3.4.21.-] 
K08663 GZMK; granzyme K [EC:3.4.21.-] 
K08649 GZMM; granzyme M [EC:3.4.21.-] 
K01329 CMA1; chymase [EC:3.4.21.39] 
K01329 CMA1; chymase [EC:3.4.21.39] 
K01326 CELA1; pancreatic elastase I [EC:3.4.21.36] 
K01346 CELA2; pancreatic elastase II [EC:3.4.21.71] 
K01345 CELA3; pancreatic endopeptidase E [EC:3.4.21.70] 
K01311 CTRC; chymotrypsin C [EC:3.4.21.2] 
K01325 KLK1_2; tissue kallikrein [EC:3.4.21.35] 
K01324 KLKB1; plasma kallikrein [EC:3.4.21.34] 
K09617 KLK5; kallikrein 5 [EC:3.4.21.-] 
K08667 KLK6; kallikrein 6 [EC:3.4.21.-] 
K08668 KLK7; kallikrein 7 [EC:3.4.21.117] 
K08650 KLK8; kallikrein 8 [EC:3.4.21.118] 
K09618 KLK9; kallikrein 9 [EC:3.4.21.-] 
K09619 KLK10; kallikrein 10 [EC:3.4.21.-] 
K09620 KLK11; kallikrein 11 [EC:3.4.21.-] 
K09621 KLK12; kallikrein 12 [EC:3.4.21.-] 
K09463 KLK13; kallikrein 13 [EC:3.4.21.119] 
K09622 KLK14; kallikrein 14 [EC:3.4.21.-] 
K09623 KLK15; kallikrein 15 [EC:3.4.21.-] 
K24791 C1RL; complement C1r subcomponent-like protein [EC:3.4.21.-] 
K03992 MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-] 
K03993 MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104] 
K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41] 
K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42] 
K01335 CFB; complement factor B [EC:3.4.21.47] 
K01334 CFD; complement factor D [EC:3.4.21.46] 
K01333 CFI; complement factor I [EC:3.4.21.45] 
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5] 
K01320 F7; coagulation factor VII [EC:3.4.21.21] 
K01321 F9; coagulation factor IX (Christmas factor) [EC:3.4.21.22] 
K01314 F10; coagulation factor X [EC:3.4.21.6] 
K01328 F12; coagulation factor XII (Hageman factor) [EC:3.4.21.38] 
K01344 PROC; protein C (activated) [EC:3.4.21.69] 
K01317 ACR; acrosin [EC:3.4.21.10] 
K08665 HPN; hepsin [EC:3.4.21.106] 
K09631 HGFAC; hepatocyte growth factor activator [EC:3.4.21.-] 
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68] 
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73] 
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122] 
K09634 TMPRSS3; transmembrane protease serine 3 [EC:3.4.21.-] 
K09635 TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-] 
K09636 TMPRSS5; transmembrane protease serine 5 [EC:3.4.21.-] 
K09637 TMPRSS6; transmembrane protease serine 6 [EC:3.4.21.-] 
K09638 TMPRSS7; transmembrane protease serine 7 [EC:3.4.21.-] 
K09640 TMPRSS9; transmembrane protease serine 9 [EC:3.4.21.-] 
K09750 TMPRSS11A; transmembrane protease serine 11A [EC:3.4.21.-] 
K09751 TMPRSS11B; transmembrane protease serine 11B [EC:3.4.21.-] 
K14359 TMPRSS11C; transmembrane protease serine 11C [EC:3.4.21.-] 
K09641 TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-] 
K09642 TMPRSS11E; transmembrane protease serine 11E [EC:3.4.21.-] 
K09752 TMPRSS11F; transmembrane protease serine 11F [EC:3.4.21.-] 
K09643 TMPRSS13; transmembrane protease serine 13 
K09632 CTRL; chymotrypsin-like protease [EC:3.4.21.-] 
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109] 
K24665 AZU1; azurocidin 
K16142 HP; haptoglobin 
K23441 MST1; hepatocyte growth factor-like protein 
K08784 HTRA1; HtrA serine peptidase 1 [EC:3.4.21.-] 
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108] 
K08785 HTRA3; HtrA serine peptidase 3 [EC:3.4.21.-] 
K08786 HTRA4; HtrA serine peptidase 4 [EC:3.4.21.-] 
K23012 TYSND1; peroxisomal leader peptide-processing protease [EC:3.4.21.-] 
K09627 PRSS23; serine protease 23 [EC:3.4.21.-] 
   Family S3: togavirin family
   Family S6
   Family S7: flavivirin family
   Family S8: subtilisin family
   Family S9: prolyl oligopeptidase family
   Family S10
   Family S11: D-Ala-D-Ala carboxypeptidase A family
   Family S12: D-Ala-D-Ala carboxypeptidase B family
   Family S13: D-Ala-D-Ala peptidase C family
   Family S14: ClpP endopeptidase family
   Family S15
   Family S16: lon protease family
   Family S21: assemblin family
   Family S24: LexA family
   Family S26: signal peptidase I family
   Family S28
   Family S31
   Family S32
   Family S33
   Family S41: C-terminal processing peptidase family
   Family S45
   Family S49: protease IV family
   Family S50
   Family S51
   Family S53
   Family S54: Rhomboid family
   Family S55: SpoIVB peptidase family
   Family S62
   Family S66
   Family S77: phage prohead processing peptidase family
   Family S78
 
 Threonine peptidases
 
 Peptidases of unknown catalytic type
 
 Peptidase inhibitors

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Last updated: June 20, 2025
Classification taken and modified from MEROPS