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Entry | Name | Description | Category | Pathway | Gene |
---|---|---|---|---|---|
H00342 | Tuberculosis | Tuberculosis is an infectious disease caused by strains of mycobacteria, mainly Mycobacterium tuberculosis, resulting in an estimated two million deaths each year worldwide, more than from any other single ... | Bacterial infectious disease | hsa05152 Tuberculosis |
IFNG (protection) [HSA:3458] [KO:K04687] IFNGR1 (susceptibility/protection) [HSA:3459] [KO:K05132] IFNGR2 [HSA:3460] [KO:K05133] HLA-DRB1 (susceptibility) [HSA:3123] [KO:K06752] HLA-DQB1 (susceptibility) [HSA:3119] [KO:K06752] SLC11A1 (susceptibility) [HSA:6556] [KO:K12347] VDR (susceptibility) [HSA:7421] [KO:K08539] MBL2 (protection) [HSA:4153] [KO:K03991] CCL2 (susceptibility) [HSA:6347] [KO:K14624] CD209 (susceptibility) [HSA:30835] [KO:K06563] CISH (susceptibility) [HSA:1154] [KO:K04701] IRGM (protection) [HSA:345611] [KO:K14139] SP110 (susceptibility) [HSA:3431] [KO:K24503] TIRAP (protection) [HSA:114609] [KO:K05403] TLR2 (susceptibility) [HSA:7097] [KO:K10159] |
H00361 | Malaria | Malaria, the most common parasitic disease in the world, is caused by Plasmodium parasites that are transmitted by female Anopheline mosquitoes. Plasmodium infections result in a spectrum of clinical effects ... | Parasitic infectious disease | hsa05144 Malaria |
ACKR1 (protection) [HSA:2532] [KO:K06574] CD36 (susceptibility/reduced risk) [HSA:948] [KO:K06259] CISH (susceptibility) [HSA:1154] [KO:K04701] CR1 (resistance) [HSA:1378] [KO:K04011] FCGR2A (susceptibility) [HSA:2212] [KO:K06472] FCGR2B (resistance) [HSA:2213] [KO:K12560] G6PD (resistance) [HSA:2539] [KO:K00036] GYPA (resistance) [HSA:2993] [KO:K06575] GYPB (resistance) [HSA:2994] [KO:K20925] GYPC (resistance) [HSA:2995] [KO:K06576] HBB (resistance) [HSA:3043] [KO:K13823] ICAM1 (susceptibility) [HSA:3383] [KO:K06490] NOS2 (resistance) [HSA:4843] [KO:K13241] SLC4A1 (resistance) [HSA:6521] [KO:K06573] TIRAP (protection) [HSA:114609] [KO:K05403] TNF (susceptibility) [HSA:7124] [KO:K03156] |
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