KEGG    Network variation - Gastric cancer
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ENTRYnt06261
NameGastric cancer
CategoryDisease view; Cancer
Pathwayhsa05226 Gastric cancer
DiseaseH00018 Gastric cancer
Display drug-target relation   disease type
ERK signaling
N00021    EGF(ERBB2+EGFR)GRB2SOSRASRAFMEKERK
N00252    EGF(ERBB2*+EGFR)GRB2SOSRASRAFMEKERK
N00019    FGFFGFRGRB2SOSRASRAFMEKERK
N00020      FGFR*GRB2SOSRASRAFMEKERK
N00216    HGFMETGRB2SOSRASRAFMEKERK
N00259      MET*GRB2SOSRASRAFMEKERK
N00012            (KRAS*,NRAS*)RAFMEKERKCCND1
 
PI3K signaling
N00284      AREGEGFRPI3KPIP3AKTMTORS6K
N00253      EGF(ERBB2*+EGFR)PI3KPIP3AKTMTORS6K
N00037      FGFFGFRPI3KPIP3AKTMTORS6K
N00038        FGFR*PI3KPIP3AKTMTOR
N00043    HGFMETGAB1PI3KPIP3AKTBAD
N00260      MET*GAB1PI3KPIP3AKTMTOR
 
WNT signaling
N00056    WNT(FZD+LRP5/6)(DVL+FRAT)(GSK3B+AXIN+APC)CTNNB1TCF/LEF(MYC,CCND1)
N00057        (GSK3B+AXIN)APC*CTNNB1TCF/LEF(BIRC5,MYC,CCND1)
N00257          CDH1*CTNNB1TCF/LEF(MYC,CCND1)
N00258          CDH1*CTNNB1TCF/LEF(MYC,CCND1)
 
TGFB signaling
N00063    TGFB(TGFBR2+TGFBR1)(SMAD2,SMAD3)=SMAD4
N00256      (TGFBR2+TGFBR1*)(SMAD2,SMAD3)
 
Cell cycle
N00091    (SCF+SKP2)CDKN1B((CCNA,CCNE)+CDK2)RB1E2F
N00254      CDKN1B*(CCNE+CDK2)RB1E2F
N00255        (CCNE*+CDK2)RB1E2F
 
Telomerase activity
N00239    TERCDNA
N00240    (TERT*+TERC)DNA
 
Transcription
N00115    TP53*(CDKN1A,GADD45,BAX..
N00250    CDX2*(MUC2,CDH17,REG4,A..
N00251    CDX2*SHH