KEGG   PATHWAY: btax04144
Entry
btax04144                   Pathway                                
Name
Endocytosis - Budorcas taxicolor (takin)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
btax04144  Endocytosis
btax04144

Other DBs
GO: 0006897
Organism
Budorcas taxicolor (takin) [GN:btax]
Gene
128053987  ARF6; ADP-ribosylation factor 6 [KO:K07941]
128051310  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
128045470  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
128052473  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
128056818  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
128064731  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
128046524  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
128056837  DNM1; dynamin-1 [KO:K01528] [EC:3.6.5.5]
128061893  DNM3; dynamin-3 [KO:K01528] [EC:3.6.5.5]
128051237  DNM2; dynamin-2 isoform X1 [KO:K23484] [EC:3.6.5.5]
128052033  CLTA; clathrin light chain A isoform X1 [KO:K04644]
128051210  CLTB; clathrin light chain B isoform X1 [KO:K04645]
128064910  CLTC; clathrin heavy chain 1 isoform X1 [KO:K04646]
128069258  AP2A2; AP-2 complex subunit alpha-2 isoform X1 [KO:K11824]
128062875  AP2A1; AP-2 complex subunit alpha-1 [KO:K11824]
128064373  AP2B1; AP-2 complex subunit beta [KO:K11825]
128055038  AP2M1; AP-2 complex subunit mu [KO:K11826]
128063451  AP2S1; AP-2 complex subunit sigma [KO:K11827]
128062913  EHD2; EH domain-containing protein 2 [KO:K12469]
128051987  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
128048354  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
128044524  ZFYVE9; zinc finger FYVE domain-containing protein 9 isoform X1 [KO:K04679]
128051193  ZFYVE16; zinc finger FYVE domain-containing protein 16 [KO:K04679]
128066395  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
128067292  SMAD2; mothers against decapentaplegic homolog 2 [KO:K04500]
128054493  SMAD3; mothers against decapentaplegic homolog 3 [KO:K23605]
128045410  TFRC; transferrin receptor protein 1 [KO:K06503]
128051614  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
128049579  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
128067669  FGFR2; fibroblast growth factor receptor 2 [KO:K05093] [EC:2.7.10.1]
128049397  FGFR3; fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
128050311  FGFR4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
128066571  IGF1R; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
128060264  CBL; E3 ubiquitin-protein ligase CBL [KO:K04707] [EC:2.3.2.27]
128053306  CBLB; E3 ubiquitin-protein ligase CBL-B [KO:K22517] [EC:2.3.2.27]
128063643  CBLC; E3 ubiquitin-protein ligase CBL-C [KO:K22518] [EC:2.3.2.27]
128069789  SH3KBP1; SH3 domain-containing kinase-binding protein 1 isoform X1 [KO:K12470]
128050587  SH3GL1; endophilin-A2 [KO:K11247]
128052402  SH3GL2; endophilin-A1 [KO:K11247]
128066684  SH3GL3; endophilin-A3 [KO:K11247]
128044493  SH3GLB1; endophilin-B1 isoform X1 [KO:K11248]
128055234  SH3GLB2; endophilin-B2 isoform X1 [KO:K21269]
128070337  BIN1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
128046255  AMPH; LOW QUALITY PROTEIN: amphiphysin [KO:K12562]
128063314  EPN1; epsin-1 [KO:K12471]
128064518  EPN3; epsin-3 [KO:K12471]
128065509  EPN2; epsin-2 isoform X1 [KO:K12471]
128050392  EPS15L1; epidermal growth factor receptor substrate 15-like 1 isoform X1 [KO:K12472]
128045689  EPS15; epidermal growth factor receptor substrate 15 isoform X1 [KO:K12472]
128057668  SPART; spartin [KO:K19366]
128053871  NEDD4; E3 ubiquitin-protein ligase NEDD4 [KO:K10591] [EC:2.3.2.26]
128067355  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
128047314  MDM2; E3 ubiquitin-protein ligase Mdm2 [KO:K06643] [EC:2.3.2.27]
128060227  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
128047292  RNF41; E3 ubiquitin-protein ligase NRDP1 isoform X1 [KO:K11981] [EC:2.3.2.27]
128058832  ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 [KO:K05632] [EC:2.3.2.26]
128064283  SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 [KO:K04678] [EC:2.3.2.26]
128065624  SMURF2; E3 ubiquitin-protein ligase SMURF2 [KO:K04678] [EC:2.3.2.26]
128059672  WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
128050700  LDLR; low-density lipoprotein receptor [KO:K12473]
128063737  LDLRAP1; low density lipoprotein receptor adapter protein 1 [KO:K12474]
128066004  DAB2; disabled homolog 2 isoform X1 [KO:K12475]
128049778  C-C chemokine receptor type 5 [KO:K04180]
128043368  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
128043506  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
128070914  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
128057827  GRK1; rhodopsin kinase GRK1 [KO:K00909] [EC:2.7.11.14]
128055905  GRK7; rhodopsin kinase GRK7 [KO:K00909] [EC:2.7.11.14]
128062244  GRK3; beta-adrenergic receptor kinase 2 [KO:K00910] [EC:2.7.11.15]
128068499  GRK2; beta-adrenergic receptor kinase 1 [KO:K00910] [EC:2.7.11.15]
128050404  GRK6; G protein-coupled receptor kinase 6 [KO:K08291] [EC:2.7.11.16]
128067756  GRK5; G protein-coupled receptor kinase 5 [KO:K08291] [EC:2.7.11.16]
128049405  GRK4; G protein-coupled receptor kinase 4 [KO:K08291] [EC:2.7.11.16]
128064406  ARRB2; beta-arrestin-2 [KO:K04439]
128059802  ARRB1; beta-arrestin-1 isoform X1 [KO:K04439]
128046475  WASL; actin nucleation-promoting factor WASL [KO:K23612]
128055441  ACTR2; actin-related protein 2 isoform X1 [KO:K17260]
128047021  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
128066761  ACTR3; actin-related protein 3 [KO:K18584]
128061543  actin-related protein 3-like [KO:K18584]
128064601  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
128052285  actin-related protein 2/3 complex subunit 1A-like [KO:K05757]
128066903  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
128058627  actin-related protein 2/3 complex subunit 2 [KO:K05758]
128068927  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
128052330  actin-related protein 2/3 complex subunit 3 [KO:K05756]
128062574  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
128043440  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
128051119  actin-related protein 2/3 complex subunit 4-like [KO:K05755]
128056088  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
128061514  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
128043298  WIPF1; WAS/WASL-interacting protein family member 1 [KO:K19475]
128065048  WIPF2; WAS/WASL-interacting protein family member 2 [KO:K19475]
128046434  WIPF3; WAS/WASL-interacting protein family member 3 [KO:K19475]
128044370  HSPA6; heat shock 70 kDa protein 6 [KO:K03283]
128061031  HSPA8; heat shock cognate 71 kDa protein isoform X1 [KO:K03283]
128055080  heat shock 70 kDa protein 1A [KO:K03283]
128055295  heat shock 70 kDa protein 1-like [KO:K03283]
128045243  DNAJC6; putative tyrosine-protein phosphatase auxilin [KO:K09526]
128071381  WASH complex subunit 4-like [KO:K18465]
128047990  WASHC4; WASH complex subunit 4 [KO:K18465]
128059117  WASHC5; WASH complex subunit 5 isoform X1 [KO:K18464]
128048413  WASHC2A; WASH complex subunit 2A isoform X1 [KO:K18462]
128047651  WASHC1; WASH complex subunit 1 [KO:K18461]
128048501  WASHC3; WASH complex subunit 3 isoform X1 [KO:K18463]
128058506  F-actin-capping protein subunit alpha-1 [KO:K10364]
128045535  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
128046254  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
128054300  LOW QUALITY PROTEIN: F-actin-capping protein subunit alpha-2-like [KO:K10364]
128048799  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
128067951  CAPZB; F-actin-capping protein subunit beta [KO:K10365]
128062573  VPS29; vacuolar protein sorting-associated protein 29 [KO:K18467]
128060146  VPS26B; vacuolar protein sorting-associated protein 26B [KO:K18466]
128047880  VPS26A; vacuolar protein sorting-associated protein 26A [KO:K18466]
128063095  VPS35; vacuolar protein sorting-associated protein 35 [KO:K18468]
128070038  SNX12; sorting nexin-12 isoform X1 [KO:K17918]
128053037  SNX3; sorting nexin-3 [KO:K17918]
128054130  USP8; ubiquitin carboxyl-terminal hydrolase 8 [KO:K11839] [EC:3.4.19.12]
128056089  STAMBP; STAM-binding protein [KO:K11866] [EC:3.4.19.12]
128044528  RAB7A; ras-related protein Rab-7a [KO:K07897]
128064460  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
128058274  STAM; signal transducing adapter molecule 1 [KO:K04705]
128060657  STAM2; signal transducing adapter molecule 2 [KO:K04705]
128068859  TSG101; tumor susceptibility gene 101 protein [KO:K12183]
128056101  MVB12B; multivesicular body subunit 12B isoform X1 [KO:K12186]
128051252  MVB12A; multivesicular body subunit 12A [KO:K12186]
128059284  VPS28; vacuolar protein sorting-associated protein 28 homolog [KO:K12184]
128062016  VPS37D; vacuolar protein sorting-associated protein 37D [KO:K12185]
128068244  VPS37A; vacuolar protein sorting-associated protein 37A [KO:K12185]
128062311  VPS37B; vacuolar protein sorting-associated protein 37B [KO:K12185]
128068678  VPS37C; vacuolar protein sorting-associated protein 37C [KO:K12185]
128065613  SNF8; vacuolar-sorting protein SNF8 [KO:K12188]
128057737  VPS36; vacuolar protein-sorting-associated protein 36 [KO:K12190]
128064933  VPS25; vacuolar protein-sorting-associated protein 25 [KO:K12189]
128065000  CHMP6; charged multivesicular body protein 6 isoform X1 [KO:K12195]
128058302  CHMP4B; charged multivesicular body protein 4b [KO:K12194]
128053796  CHMP4A; charged multivesicular body protein 4a isoform X1 [KO:K12194]
128059498  CHMP4C; charged multivesicular body protein 4c [KO:K24782]
128064878  charged multivesicular body protein 3 [KO:K12193]
128063071  CHMP2A; charged multivesicular body protein 2a [KO:K12191]
128053922  CHMP2B; charged multivesicular body protein 2b [KO:K12192]
128052163  CHMP7; charged multivesicular body protein 7 isoform X1 [KO:K15053]
128063340  VPS4A; vacuolar protein sorting-associated protein 4A isoform X1 [KO:K12196]
128071115  vacuolar protein sorting-associated protein 4A isoform X1 [KO:K12196]
128067400  VPS4B; vacuolar protein sorting-associated protein 4B [KO:K12196]
128053290  VTA1; vacuolar protein sorting-associated protein VTA1 homolog isoform X1 [KO:K12199]
128063036  CHMP1A; charged multivesicular body protein 1a [KO:K12197]
128067339  CHMP1B; charged multivesicular body protein 1b [KO:K12197]
128063602  charged multivesicular body protein 5-like [KO:K12198]
128052157  CHMP5; charged multivesicular body protein 5 [KO:K12198]
128063283  IST1; IST1 homolog isoform X1 [KO:K19476]
128048002  PDCD6IP; programmed cell death 6-interacting protein isoform X1 [KO:K12200]
128054150  SPG21; maspardin [KO:K19367]
128053042  IGF2R; cation-independent mannose-6-phosphate receptor [KO:K06564]
128050811  SNX2; sorting nexin-2 [KO:K17917]
128046899  sorting nexin-2-like [KO:K17917]
128053767  SNX1; sorting nexin-1 [KO:K17917]
128058372  SNX5; sorting nexin-5 [KO:K17920]
128060099  sorting nexin-5-like [KO:K17920]
128066615  SNX6; sorting nexin-6 isoform X1 [KO:K17920]
128068587  SNX32; LOW QUALITY PROTEIN: sorting nexin-32 [KO:K17920]
128058174  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
128068689  HRAS; GTPase HRas isoform X1 [KO:K02833]
128058762  IL2RA; interleukin-2 receptor subunit alpha [KO:K05068]
128048204  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
128070243  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
128044567  RHOA; transforming protein RhoA [KO:K04513]
128050979  H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
128055236  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055280  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055281  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055305  BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128060322  folate receptor alpha [KO:K13649]
128060409  folate receptor beta-like [KO:K13649]
128060534  folate receptor alpha-like [KO:K13649]
128046440  CAV1; caveolin-1 isoform X1 [KO:K06278]
128046728  CAV2; caveolin-2 [KO:K12958]
128046664  CAV3; caveolin-3 [KO:K12959]
128056200  EHD3; EH domain-containing protein 3 [KO:K12476]
128053919  EHD4; EH domain-containing protein 4 [KO:K12477]
128048082  EEA1; early endosome antigen 1 [KO:K12478]
128060293  RAB5A; ras-related protein Rab-5A [KO:K07887]
128045062  ras-related protein Rab-5B-like [KO:K07888]
128047345  RAB5B; ras-related protein Rab-5B [KO:K07888]
128064681  RAB5C; ras-related protein Rab-5C [KO:K07889]
128064389  RABEP1; rab GTPase-binding effector protein 1 isoform X1 [KO:K12480]
128046796  RBSN; rabenosyn-5 [KO:K12481]
128050574  RUFY1; RUN and FYVE domain-containing protein 1 isoform X1 [KO:K12482]
128047757  RUFY2; RUN and FYVE domain-containing protein 2 [KO:K12482]
128068497  EHD1; EH domain-containing protein 1 [KO:K12483]
128044746  VPS45; vacuolar protein sorting-associated protein 45 [KO:K12479]
128050267  SNX4; sorting nexin-4 [KO:K17919]
128058381  RAB22A; ras-related protein Rab-22A [KO:K07891]
128067308  RAB31; ras-related protein Rab-31 isoform X1 [KO:K07891]
128055926  RAB10; ras-related protein Rab-10 [KO:K07903]
128050786  RAB8A; ras-related protein Rab-8A [KO:K07901]
128062182  RAB35; ras-related protein Rab-35 [KO:K07876]
128053978  RAB11A; ras-related protein Rab-11A [KO:K07904]
128067946  ras-related protein Rab-11A-like [KO:K07904]
128050302  RAB11B; ras-related protein Rab-11B [KO:K07905]
128067969  RAB11FIP2; rab11 family-interacting protein 2 [KO:K12484]
128068304  RAB11FIP1; rab11 family-interacting protein 1 [KO:K12484]
128055849  rab11 family-interacting protein 5-like [KO:K12484]
128068024  ZFYVE27; protrudin isoform X1 [KO:K19368]
128069375  KIF5C; kinesin heavy chain [KO:K10396]
128058018  KIF5B; kinesin-1 heavy chain [KO:K10396]
128047545  KIF5A; kinesin heavy chain [KO:K10396]
128069735  RAB11FIP3; rab11 family-interacting protein 3 [KO:K12485]
128065254  RAB11FIP4; rab11 family-interacting protein 4 [KO:K12485]
128058577  PARD3; partitioning defective 3 homolog isoform X1 [KO:K04237]
128063627  PARD6A; partitioning defective 6 homolog alpha [KO:K06093]
128058731  PARD6B; partitioning defective 6 homolog beta [KO:K06093]
128067538  PARD6G; partitioning defective 6 homolog gamma [KO:K06093]
128061175  PRKCZ; protein kinase C zeta type isoform X1 [KO:K18952] [EC:2.7.11.13]
128047071  PRKCI; protein kinase C iota type [KO:K06069] [EC:2.7.11.13]
128066401  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
128044796  SMAP2; stromal membrane-associated protein 2 [KO:K12486]
128059135  SMAP1; stromal membrane-associated protein 1 [KO:K12486]
128064479  GIT1; ARF GTPase-activating protein GIT1 [KO:K05737]
128062079  GIT2; ARF GTPase-activating protein GIT2 isoform X1 [KO:K12487]
128043396  ASAP3; LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [KO:K12488]
128059427  ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12488]
128055073  ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 [KO:K12488]
128045400  ACAP2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 [KO:K12489]
128064868  ACAP1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [KO:K12489]
128061163  ACAP3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12489]
128060132  ARAP1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K18439]
128049787  ARAP2; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 [KO:K18440]
128050452  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [KO:K12490]
128045821  AGAP1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12491]
128046424  AGAP3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12491]
128047696  AGAP2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 [KO:K17848]
128058438  ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [KO:K12492]
128060026  ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
128047478  ARFGAP3; ADP-ribosylation factor GTPase-activating protein 3 isoform X1 [KO:K12493]
128056258  PSD4; PH and SEC7 domain-containing protein 4 [KO:K12494]
128050873  PSD2; PH and SEC7 domain-containing protein 2 [KO:K12494]
128067795  PSD; PH and SEC7 domain-containing protein 1 [KO:K12494]
128068210  PSD3; PH and SEC7 domain-containing protein 3 [KO:K12494]
128069691  IQSEC2; IQ motif and SEC7 domain-containing protein 2 [KO:K12495]
128048019  IQSEC3; IQ motif and SEC7 domain-containing protein 3 [KO:K12495]
128062891  IQSEC1; IQ motif and SEC7 domain-containing protein 1 isoform X1 [KO:K12495]
128043466  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
128065356  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
128047768  CYTH4; cytohesin-4 [KO:K18441]
128062957  CYTH2; cytohesin-2 [KO:K18441]
128058016  ARFGEF2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 [KO:K18442]
128059491  ARFGEF1; brefeldin A-inhibited guanine nucleotide-exchange protein 1 [KO:K18442]
128067895  GBF1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1 [KO:K18443]
128051338  ARF1; ADP-ribosylation factor 1 [KO:K07937]
128064660  ADP-ribosylation factor 2 [KO:K07937]
128047245  ARF3; ADP-ribosylation factor 3 [KO:K07938]
128048764  ADP-ribosylation factor 3-like [KO:K07938]
128071491  ARF4; ADP-ribosylation factor 4 [KO:K07939]
128052386  ADP-ribosylation factor 4-like [KO:K07939]
128046670  ARF5; ADP-ribosylation factor 5 [KO:K07940]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
btax04060  Cytokine-cytokine receptor interaction
btax04070  Phosphatidylinositol signaling system
btax04130  SNARE interactions in vesicular transport
btax04142  Lysosome
btax04350  TGF-beta signaling pathway
KO pathway
ko04144   
LinkDB

DBGET integrated database retrieval system