 | | PATHWAY: hsa00970 | |
| Entry |
|
| Name |
Aminoacyl-tRNA biosynthesis - Homo sapiens (human) |
| Class |
Genetic Information Processing; Translation
|
| Pathway map |

|
| Drug |
| D12794 | Bersiporocin (USAN/INN) |
| D12795 | Bersiporocin hydrochloride (USAN) |
|
| Organism |
Homo sapiens (human) [GN: hsa]
|
| Gene |
| 10352 | WARS2; tryptophan--tRNA ligase, mitochondrial isoform 1 precursor [KO:K01867] [EC:6.1.1.2] |
| 124454 | EARS2; nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial isoform 1 [KO:K01885] [EC:6.1.1.17] |
| 23438 | HARS2; histidine--tRNA ligase, mitochondrial isoform 1 precursor [KO:K01892] [EC:6.1.1.21] |
| 51091 | SEPSECS; O-phosphoseryl-tRNA(Sec) selenium transferase isoform 1 [KO:K03341] [EC:2.9.1.2] |
| 5188 | GATB; glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial isoform 1 precursor [KO:K02434] [EC:6.3.5.6 6.3.5.7] |
| 57038 | RARS2; probable arginine--tRNA ligase, mitochondrial isoform 1 precursor [KO:K01887] [EC:6.1.1.19] |
| 57176 | VARS2; valine--tRNA ligase, mitochondrial isoform 2 precursor [KO:K01873] [EC:6.1.1.9] |
|
| Compound |
| C00234 | 10-Formyltetrahydrofolate |
| C03402 | L-Asparaginyl-tRNA(Asn) |
| C03511 | L-Phenylalanyl-tRNA(Phe) |
| C03512 | L-Tryptophanyl-tRNA(Trp) |
| C06482 | L-Selenocysteinyl-tRNA(Sec) |
| C16638 | O-Phosphoseryl-tRNA(Sec) |
| C17022 | O-Phosphoseryl-tRNA(Cys) |
|
| Reference |
|
| Authors |
Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D |
| Title |
From one amino acid to another: tRNA-dependent amino acid biosynthesis. |
| Journal |
|
| Reference |
|
| Authors |
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D |
| Title |
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine. |
| Journal |
|
Related pathway |
| hsa00250 | Alanine, aspartate and glutamate metabolism |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa00270 | Cysteine and methionine metabolism |
| hsa00290 | Valine, leucine and isoleucine biosynthesis |
| hsa00330 | Arginine and proline metabolism |
| hsa00400 | Phenylalanine, tyrosine and tryptophan biosynthesis |
|
| KO pathway |
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