KEGG   PATHWAY: mlx04144
Entry
mlx04144                    Pathway                                
Name
Endocytosis - Mirounga leonina (Southern elephant seal)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
mlx04144  Endocytosis
mlx04144

Other DBs
GO: 0006897
Organism
Mirounga leonina (Southern elephant seal) [GN:mlx]
Gene
117997719  [KO:K07937]
117997806  EPN1; epsin-1 isoform X1 [KO:K12471]
117997828  IQSEC2; IQ motif and SEC7 domain-containing protein 2 isoform X1 [KO:K12495]
117997883  CHMP2A; charged multivesicular body protein 2a [KO:K12191]
117998035  CBLC; E3 ubiquitin-protein ligase CBL-C [KO:K22518] [EC:2.3.2.27]
117998184  AP2S1; AP-2 complex subunit sigma isoform X1 [KO:K11827]
117998208  EHD2; EH domain-containing protein 2 [KO:K12469]
117998222  CYTH2; cytohesin-2 [KO:K18441]
117998265  AP2A1; AP-2 complex subunit alpha-1 isoform X1 [KO:K11824]
117998425  KIF5B; kinesin-1 heavy chain isoform X1 [KO:K10396] [EC:5.6.1.3]
117998599  ARFGAP3; ADP-ribosylation factor GTPase-activating protein 3 [KO:K12493]
117998714  CYTH4; cytohesin-4 [KO:K18441]
117998718  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
117998785  WASHC4; WASH complex subunit 4 isoform X1 [KO:K18465]
117998819  WASHC3; WASH complex subunit 3 isoform X1 [KO:K18463]
117998895  EEA1; early endosome antigen 1 [KO:K12478]
117998914  [KO:K05756]
117999039  SH3GL2; endophilin-A1 isoform X1 [KO:K11247]
117999201  VPS37D; vacuolar protein sorting-associated protein 37D [KO:K12185]
117999340  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
117999354  [KO:K12194]
117999361  SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 [KO:K04678] [EC:2.3.2.26]
117999364  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
117999367  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
117999766  CLTCL1; clathrin heavy chain 2 isoform X1 [KO:K04646]
117999881  [KO:K12188]
117999945  RABEP1; rab GTPase-binding effector protein 1 isoform X1 [KO:K12480]
117999965  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
117999973  ARRB2; beta-arrestin-2 [KO:K04439]
118000002  ACAP1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [KO:K12489]
118000127  EPN2; epsin-2 isoform X1 [KO:K12471]
118000288  VPS45; vacuolar protein sorting-associated protein 45 isoform X1 [KO:K12479]
118000335  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
118000898  [KO:K06751]
118000934  VTA1; vacuolar protein sorting-associated protein VTA1 homolog isoform X1 [KO:K12199]
118001060  [KO:K05756]
118001246  SMAP1; stromal membrane-associated protein 1 isoform X1 [KO:K12486]
118001342  [KO:K17917]
118001546  PDCD6IP; programmed cell death 6-interacting protein isoform X1 [KO:K12200]
118001572  SNX3; sorting nexin-3 isoform X1 [KO:K17918]
118001837  [KO:K06564]
118001960  [KO:K06564]
118002026  ARF6; ADP-ribosylation factor 6 isoform X1 [KO:K07941]
118002661  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
118002848  [KO:K17920]
118002894  [KO:K17920]
118003146  RAB5A; ras-related protein Rab-5A [KO:K07887]
118003298  RAB11A; ras-related protein Rab-11A [KO:K07904]
118003380  CHMP4A; charged multivesicular body protein 4a isoform X1 [KO:K12194]
118003407  NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 [KO:K10591] [EC:2.3.2.26]
118003419  EHD4; EH domain-containing protein 4 [KO:K12477]
118003430  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
118003613  USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1 [KO:K11839] [EC:3.4.19.12]
118003633  SPG21; maspardin isoform X1 [KO:K19367]
118003638  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
118003701  SNX1; sorting nexin-1 [KO:K17917]
118004271  ARRB1; beta-arrestin-1 isoform X1 [KO:K04439]
118004289  ARAP1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K18439]
118004567  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
118004611  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
118004615  GRK7; rhodopsin kinase GRK7 [KO:K00909] [EC:2.7.11.14]
118004760  PARD6G; partitioning defective 6 homolog gamma [KO:K06093]
118004774  [KO:K04393]
118004776  VPS4B; vacuolar protein sorting-associated protein 4B [KO:K12196]
118004875  RBSN; rabenosyn-5 isoform X1 [KO:K12481]
118004927  [KO:K04180]
118004985  SH3GL1; endophilin-A2 isoform X1 [KO:K11247]
118005026  RAB8A; ras-related protein Rab-8A [KO:K07901]
118005272  IQSEC1; IQ motif and SEC7 domain-containing protein 1 isoform X1 [KO:K12495]
118005319  CAV3; caveolin-3 [KO:K12959]
118005519  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
118005670  RHOA; transforming protein RhoA [KO:K04513]
118005672  DNM2; dynamin-2 isoform X1 [KO:K23484]
118005729  EPS15L1; epidermal growth factor receptor substrate 15-like 1 isoform X1 [KO:K12472]
118005771  RAB7A; ras-related protein Rab-7a [KO:K07897]
118005787  ARF4; ADP-ribosylation factor 4 [KO:K07939]
118005822  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
118005831  RAB11B; ras-related protein Rab-11B [KO:K07905]
118005983  LDLR; low-density lipoprotein receptor isoform X1 [KO:K12473]
118006003  MVB12A; multivesicular body subunit 12A [KO:K12186]
118006199  PRKCI; protein kinase C iota type [KO:K06069] [EC:2.7.11.13]
118006301  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
118006403  [KO:K12475]
118006539  [KO:K12475]
118006889  AP2M1; AP-2 complex subunit mu isoform X1 [KO:K11826]
118006961  ACAP2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K12489]
118006987  TFRC; transferrin receptor protein 1 isoform X1 [KO:K06503]
118006999  SNX4; sorting nexin-4 [KO:K17919]
118007136  CBLB; E3 ubiquitin-protein ligase CBL-B [KO:K22517] [EC:2.3.2.27]
118007274  [KO:K12488]
118007326  [KO:K12488]
118007461  SH3KBP1; SH3 domain-containing kinase-binding protein 1 isoform X1 [KO:K12470]
118007668  RAB10; ras-related protein Rab-10 [KO:K07903]
118007740  EHD3; EH domain-containing protein 3 [KO:K12476]
118007875  PSD4; PH and SEC7 domain-containing protein 4 isoform X1 [KO:K12494]
118007967  STAMBP; STAM-binding protein [KO:K11866] [EC:3.4.19.12]
118007978  RAB11FIP5; rab11 family-interacting protein 5 isoform X1 [KO:K12484]
118008048  ACTR2; actin-related protein 2 isoform X1 [KO:K17260]
118008426  KIF5A; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
118008591  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
118008657  AGAP2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K17848]
118008716  RNF41; E3 ubiquitin-protein ligase NRDP1 isoform X1 [KO:K11981] [EC:2.3.2.27]
118008733  RAB5B; ras-related protein Rab-5B isoform X1 [KO:K07888]
118008894  ARF3; ADP-ribosylation factor 3 [KO:K07938]
118009109  GRK1; rhodopsin kinase GRK1 [KO:K00909] [EC:2.7.11.14]
118009474  VPS36; vacuolar protein-sorting-associated protein 36 isoform X1 [KO:K12190]
118009508  SPART; spartin isoform X1 [KO:K19366]
118009897  PSD3; PH and SEC7 domain-containing protein 3 [KO:K12494]
118009970  RAB11FIP1; rab11 family-interacting protein 1 isoform X1 [KO:K12484]
118010032  VPS37A; vacuolar protein sorting-associated protein 37A isoform X1 [KO:K12185]
118010522  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
118010632  ARAP2; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 [KO:K18440]
118010768  GRK4; G protein-coupled receptor kinase 4 isoform X1 [KO:K08291] [EC:2.7.11.16]
118010795  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
118011208  SNX5; sorting nexin-5 [KO:K17920]
118011345  [KO:K04393]
118011386  CHMP4B; charged multivesicular body protein 4b [KO:K12194]
118011397  ITCH; E3 ubiquitin-protein ligase Itchy homolog [KO:K05632] [EC:2.3.2.26]
118011463  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
118011914  AGAP1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12491]
118012053  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
118012054  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
118012056  [KO:K05050]
118012312  WIPF1; WAS/WASL-interacting protein family member 1 isoform X1 [KO:K19475]
118012446  STAM2; signal transducing adapter molecule 2 isoform X1 [KO:K04705]
118012462  KIF5C; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
118012497  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
118012523  ACTR3; actin-related protein 3 [KO:K18584]
118012565  BIN1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
118012879  RAB4A; ras-related protein Rab-4A isoform X1 [KO:K07879]
118013312  CBL; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
118013335  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
118013412  VPS26B; vacuolar protein sorting-associated protein 26B [KO:K18466]
118013784  HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
118014382  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
118014473  DNM3; dynamin-3 isoform X1 [KO:K01528] [EC:3.6.5.5]
118014776  [KO:K12479]
118014895  ARFGEF1; brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1 [KO:K18442]
118014967  CHMP4C; charged multivesicular body protein 4c [KO:K24782]
118014986  WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
118015201  WASHC5; WASH complex subunit 5 isoform X1 [KO:K18464]
118015218  ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12488]
118015319  VPS28; vacuolar protein sorting-associated protein 28 homolog isoform X1 [KO:K12184]
118015670  TSG101; tumor susceptibility gene 101 protein [KO:K12183]
118015773  TRAF6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
118015821  ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
118015908  VPS37C; vacuolar protein sorting-associated protein 37C [KO:K12185]
118016014  EHD1; EH domain-containing protein 1 [KO:K12483]
118016066  SNX32; sorting nexin-32 [KO:K17920]
118016116  GRK2; beta-adrenergic receptor kinase 1 isoform X1 [KO:K00910] [EC:2.7.11.15]
118016204  AP2A2; AP-2 complex subunit alpha-2 isoform X1 [KO:K11824]
118016228  HRAS; GTPase HRas isoform X1 [KO:K02833]
118016438  RAB31; ras-related protein Rab-31 isoform X1 [KO:K07891]
118016569  SNX2; sorting nexin-2 isoform X1 [KO:K17917]
118016706  PSD2; PH and SEC7 domain-containing protein 2 [KO:K12494]
118016745  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
118016853  [KO:K10364]
118016947  ZFYVE16; zinc finger FYVE domain-containing protein 16 isoform X1 [KO:K04679]
118016980  CLTB; clathrin light chain B [KO:K04645]
118017149  FGFR4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
118017323  GRK6; G protein-coupled receptor kinase 6 isoform X1 [KO:K08291] [EC:2.7.11.16]
118017342  CHMP2B; charged multivesicular body protein 2b [KO:K12192]
118017607  SH3GLB2; endophilin-B2 isoform X1 [KO:K21269]
118017635  DNM1; LOW QUALITY PROTEIN: dynamin-1 [KO:K01528] [EC:3.6.5.5]
118017672  MVB12B; multivesicular body subunit 12B isoform X1 [KO:K12186]
118017688  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
118017874  [KO:K05756]
118017899  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
118017929  [KO:K12482]
118017949  CLTA; clathrin light chain A isoform X1 [KO:K04644]
118018026  CHMP5; charged multivesicular body protein 5 [KO:K12198]
118018110  [KO:K18466]
118018192  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1 [KO:K13712] [EC:2.7.1.68]
118018300  [KO:K12194]
118018409  VPS37B; vacuolar protein sorting-associated protein 37B [KO:K12185]
118018453  ARPC3; actin-related protein 2/3 complex subunit 3 isoform X1 [KO:K05756]
118018460  VPS29; vacuolar protein sorting-associated protein 29 isoform X1 [KO:K18467]
118018535  RAB35; ras-related protein Rab-35 [KO:K07876]
118018566  GIT2; ARF GTPase-activating protein GIT2 isoform X1 [KO:K12487]
118018603  GRK3; beta-adrenergic receptor kinase 2 isoform X1 [KO:K00910] [EC:2.7.11.15]
118018668  [KO:K12482]
118018879  [KO:K18466]
118018996  CAPZA1; F-actin-capping protein subunit alpha-1 isoform X1 [KO:K10364]
118019194  SH3GLB1; endophilin-B1 isoform X1 [KO:K11248]
118019312  DNAJC6; putative tyrosine-protein phosphatase auxilin isoform X1 [KO:K09526]
118019410  ZFYVE9; zinc finger FYVE domain-containing protein 9 isoform X1 [KO:K04679]
118019420  EPS15; epidermal growth factor receptor substrate 15 isoform X1 [KO:K12472]
118019568  SMAP2; stromal membrane-associated protein 2 isoform X1 [KO:K12486]
118019860  LDLRAP1; low density lipoprotein receptor adapter protein 1 isoform X1 [KO:K12474]
118019897  ASAP3; LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [KO:K12488]
118019913  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
118019936  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
118020095  PRKCZ; protein kinase C zeta type [KO:K18952] [EC:2.7.11.13]
118020130  ACAP3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12489]
118020648  [KO:K03283]
118020689  [KO:K05757]
118021007  CAV2; caveolin-2 [KO:K12958]
118021009  CAV1; caveolin-1 isoform X1 [KO:K06278]
118021011  CAPZA2; F-actin-capping protein subunit alpha-2 isoform X1 [KO:K10364]
118021039  WASL; neural Wiskott-Aldrich syndrome protein [KO:K23612]
118021049  ARF5; ADP-ribosylation factor 5 [KO:K07940]
118021267  [KO:K07939]
118021302  WIPF3; WAS/WASL-interacting protein family member 3 [KO:K19475]
118021527  STAM; signal transducing adapter molecule 1 isoform X1 [KO:K04705]
118021614  IL2RA; interleukin-2 receptor subunit alpha [KO:K05068]
118021658  RAB11FIP3; rab11 family-interacting protein 3 isoform X1 [KO:K12485]
118022089  CHMP7; charged multivesicular body protein 7 isoform X1 [KO:K15053]
118022977  [KO:K18462]
118023006  IGF1R; insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
118023111  SH3GL3; endophilin-A3 isoform X1 [KO:K11247]
118023448  CHMP1A; charged multivesicular body protein 1a [KO:K12197]
118023602  IST1; IST1 homolog isoform X1 [KO:K19476]
118023625  VPS4A; vacuolar protein sorting-associated protein 4A isoform X1 [KO:K12196]
118023665  PARD6A; partitioning defective 6 homolog alpha isoform X1 [KO:K06093]
118023829  VPS35; vacuolar protein sorting-associated protein 35 [KO:K18468]
118023945  ARFGEF2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1 [KO:K18442]
118023971  PARD6B; partitioning defective 6 homolog beta [KO:K06093]
118024004  RAB22A; ras-related protein Rab-22A isoform X1 [KO:K07891]
118024047  ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [KO:K12492]
118024168  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
118024185  CHMP6; charged multivesicular body protein 6 isoform X1 [KO:K12195]
118024208  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
118024363  SMURF2; E3 ubiquitin-protein ligase SMURF2 isoform X1 [KO:K04678] [EC:2.3.2.26]
118024535  EGFR; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
118024557  AMPH; amphiphysin isoform X1 [KO:K12562]
118024620  ZFYVE27; protrudin [KO:K19368]
118024628  AP2B1; AP-2 complex subunit beta isoform X1 [KO:K11825]
118024684  CLTC; clathrin heavy chain 1 isoform X1 [KO:K04646]
118024761  EPN3; epsin-3 [KO:K12471]
118024791  SNF8; vacuolar-sorting protein SNF8 [KO:K12188]
118024862  WIPF2; WAS/WASL-interacting protein family member 2 [KO:K19475]
118024904  RAB5C; ras-related protein Rab-5C [KO:K07889]
118024933  VPS25; vacuolar protein-sorting-associated protein 25 isoform X1 [KO:K12189]
118025248  [KO:K07904]
118025259  GIT1; ARF GTPase-activating protein GIT1 [KO:K05737]
118025312  RAB11FIP4; rab11 family-interacting protein 4 isoform X1 [KO:K12485]
118025457  GBF1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1 [KO:K18443]
118025470  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
118025500  IQSEC3; IQ motif and SEC7 domain-containing protein 3 isoform X1 [KO:K12495]
118025520  PSD; PH and SEC7 domain-containing protein 1 isoform X1 [KO:K12494]
118025787  WASHC1; WASH complex subunit 1 isoform X1 [KO:K18461]
118025908  [KO:K12197]
118025926  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
118026015  SNX12; sorting nexin-12 isoform X1 [KO:K17918]
118026076  [KO:K05758]
118026317  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
118026438  CHMP1B; charged multivesicular body protein 1b [KO:K12197]
118026501  [KO:K06751]
118026515  RUFY1; RUN and FYVE domain-containing protein 1 [KO:K12482]
118026595  [KO:K12194]
118026623  PARD3; partitioning defective 3 homolog isoform X1 [KO:K04237]
118026743  [KO:K06751]
118026804  AGAP3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 [KO:K12491]
118026829  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
118026885  ARF1; ADP-ribosylation factor 1 [KO:K07937]
118026908  RAB11FIP2; rab11 family-interacting protein 2 [KO:K12484]
118027000  GRK5; G protein-coupled receptor kinase 5 isoform X1 [KO:K08291] [EC:2.7.11.16]
118027176  ARL17A; ADP-ribosylation factor-like 17-like [KO:K07937]
118027178  FGFR2; fibroblast growth factor receptor 2 [KO:K05093] [EC:2.7.10.1]
118027322  HSPA1L; heat shock 70 kDa protein 1-like isoform X1 [KO:K03283]
118027349  [KO:K06751]
118027378  [KO:K06751]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
mlx04060  Cytokine-cytokine receptor interaction
mlx04070  Phosphatidylinositol signaling system
mlx04130  SNARE interactions in vesicular transport
mlx04142  Lysosome
mlx04350  TGF-beta signaling pathway
KO pathway
ko04144   

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