KEGG   PATHWAY: npd00230
Entry
npd00230                    Pathway                                
Name
Purine metabolism - Nothoprocta perdicaria (Chilean tinamou)
Class
Metabolism; Nucleotide metabolism
Pathway map
npd00230  Purine metabolism
npd00230

Module
npd_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:npd00230]
npd_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:npd00230]
npd_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:npd00230]
npd_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:npd00230]
npd_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:npd00230]
npd_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:npd00230]
Other DBs
GO: 0006163 0042278
Organism
Nothoprocta perdicaria (Chilean tinamou) [GN:npd]
Gene
112942378  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
112942546  [KO:K01587] [EC:4.1.1.21 6.3.2.6]
112942547  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
112942706  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
112943238  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
112943391  GUCY2F; LOW QUALITY PROTEIN: retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
112943432  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
112943502  AMPD3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
112943890  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
112944183  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
112944396  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
112944604  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
112944641  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
112944682  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
112944773  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
112944957  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
112945050  [KO:K00760] [EC:2.4.2.8]
112945059  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
112945245  [KO:K01081] [EC:3.1.3.5]
112945326  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
112945339  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
112945469  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
112945527  PGM1; phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
112945533  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
112945535  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
112945543  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
112945946  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
112946255  [KO:K00365] [EC:1.7.3.3]
112946478  ADSL; adenylosuccinate lyase isoform X1 [KO:K01756] [EC:4.3.2.2]
112946596  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
112947004  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
112947372  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
112947578  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
112947836  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
112947865  [KO:K12319] [EC:4.6.1.2]
112948158  GART; trifunctional purine biosynthetic protein adenosine-3 isoform X1 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
112948159  [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
112948190  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
112948214  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
112948437  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
112948757  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
112948786  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
112948956  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
112948978  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
112949192  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
112949229  GUCY1B1; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
112949263  GUCY1A1; guanylate cyclase soluble subunit alpha-1 [KO:K12318] [EC:4.6.1.2]
112949328  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
112949726  ADA; adenosine deaminase isoform X1 [KO:K01488] [EC:3.5.4.4]
112949839  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
112949949  [KO:K01081] [EC:3.1.3.5]
112950276  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
112950312  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
112950317  PDE1B; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
112950767  DGUOK; deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
112950801  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
112950809  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
112950930  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
112951187  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
112951311  [KO:K18533] [EC:2.7.4.3 2.7.4.6]
112951466  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
112951486  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
112951684  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
112951964  PDE10A; LOW QUALITY PROTEIN: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
112952111  [KO:K01081] [EC:3.1.3.5]
112952187  NPR2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
112952339  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
112952465  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
112952665  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
112952705  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
112952861  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
112952969  PRUNE1; exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
112953168  GUK1; guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
112953404  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
112953661  [KO:K00940] [EC:2.7.4.6]
112953714  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
112953927  GMPR; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
112953975  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
112954097  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
112954115  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
112954307  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
112954761  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
112954768  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
112954835  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
112954912  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
112954913  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
112954928  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
112955254  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
112955385  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
112955672  NME4; nucleoside diphosphate kinase, mitochondrial [KO:K00940] [EC:2.7.4.6]
112955673  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
112955683  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
112955826  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
112955896  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
112955911  [KO:K01510] [EC:3.6.1.5]
112955931  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
112956104  [KO:K01510] [EC:3.6.1.5]
112956431  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
112956495  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
112956953  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
112957016  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
112957029  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
112957321  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
112957951  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
112958026  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X1 [KO:K13757] [EC:3.1.4.35]
112958234  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
112958258  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
112958337  ADA2; adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
112958470  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
112958650  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
112958663  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
112959372  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
112959414  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
112959501  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
112959812  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
112960094  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
112960373  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
112960409  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
112960417  [KO:K00948] [EC:2.7.6.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
npd00030  Pentose phosphate pathway
npd00220  Arginine biosynthesis
npd00250  Alanine, aspartate and glutamate metabolism
npd00260  Glycine, serine and threonine metabolism
npd00340  Histidine metabolism
npd00630  Glyoxylate and dicarboxylate metabolism
npd00730  Thiamine metabolism
npd00740  Riboflavin metabolism
npd00790  Folate biosynthesis
KO pathway
ko00230   

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