KEGG   PATHWAY: tgt00230
Entry
tgt00230                    Pathway                                
Name
Purine metabolism - Tinamus guttatus (white-throated tinamou)
Class
Metabolism; Nucleotide metabolism
Pathway map
tgt00230  Purine metabolism
tgt00230

Module
tgt_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:tgt00230]
tgt_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tgt00230]
tgt_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tgt00230]
tgt_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tgt00230]
tgt_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:tgt00230]
tgt_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:tgt00230]
Other DBs
GO: 0006163 0042278
Organism
Tinamus guttatus (white-throated tinamou) [GN:tgt]
Gene
104569295  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104576291  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104570171  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104580783  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
104572983  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104566670  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104566671  LOW QUALITY PROTEIN: trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104572965  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104574095  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104572310  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104570703  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104577476  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
104567842  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
104569163  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type isoform X1 [KO:K01081] [EC:3.1.3.5]
104578797  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104580149  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
104571723  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104578229  PNP; LOW QUALITY PROTEIN: purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104565594  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104566735  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104577711  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104574273  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104571161  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104567112  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
104577894  NME4; nucleoside diphosphate kinase, mitochondrial [KO:K00940] [EC:2.7.4.6]
104570133  nucleoside diphosphate kinase isoform X1 [KO:K00940] [EC:2.7.4.6]
104574956  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
104577319  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104566334  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
104567463  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104573524  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104573547  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104573548  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104580100  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
104579807  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104569977  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104570938  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104566545  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104568268  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104569963  GMPR; GMP reductase 1 isoform X1 [KO:K00364] [EC:1.7.1.7]
104572982  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
104576795  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
104575426  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104575552  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104576534  ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
104572728  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104571341  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104577372  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104573631  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
104573956  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
104573744  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
104573965  ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
104566596  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104574302  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104569769  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104570492  GUCY1A3; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
104577121  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
104570491  GUCY1B3; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
104572118  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104575927  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104574464  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
104575503  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104574262  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104571317  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like [KO:K13755] [EC:3.1.4.17]
104568797  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
104569631  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
104567629  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
104576912  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
104578018  PDE3B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104578382  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
104572788  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104564728  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X1 [KO:K13757] [EC:3.1.4.35]
104565560  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104566140  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104579704  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
104568897  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104581241  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104573830  adenylosuccinate synthetase isozyme 1-like [KO:K01939] [EC:6.3.4.4]
104569758  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
104569777  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
104566673  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
104566842  LOW QUALITY PROTEIN: AMP deaminase 2-like [KO:K01490] [EC:3.5.4.6]
104573974  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104578863  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
104575626  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104567328  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104571275  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104568010  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104573000  AK2; adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
104579943  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
104571095  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
104569691  LOW QUALITY PROTEIN: adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
104570145  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
104573517  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
104567968  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104577646  venom phosphodiesterase 2-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104577657  ectonucleotide pyrophosphatase/phosphodiesterase family member 1-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104572610  cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
104564663  LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [KO:K13293] [EC:3.1.4.53]
104574775  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [KO:K13293] [EC:3.1.4.53]
104566617  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
104570053  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
104578309  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
104574613  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
104579791  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 isoform X1 [KO:K18424] [EC:3.6.1.29]
104573664  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104578549  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104565328  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tgt00030  Pentose phosphate pathway
tgt00220  Arginine biosynthesis
tgt00250  Alanine, aspartate and glutamate metabolism
tgt00260  Glycine, serine and threonine metabolism
tgt00340  Histidine metabolism
tgt00630  Glyoxylate and dicarboxylate metabolism
tgt00730  Thiamine metabolism
tgt00740  Riboflavin metabolism
tgt00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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