KEGG   PATHWAY: zab00230
Entry
zab00230                    Pathway                                
Name
Purine metabolism - Zonotrichia albicollis (white-throated sparrow)
Class
Metabolism; Nucleotide metabolism
Pathway map
zab00230  Purine metabolism
zab00230

Module
zab_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:zab00230]
zab_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:zab00230]
zab_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:zab00230]
zab_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:zab00230]
zab_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:zab00230]
zab_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:zab00230]
Other DBs
GO: 0006163 0042278
Organism
Zonotrichia albicollis (white-throated sparrow) [GN:zab]
Gene
102063830  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
102068717  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
102070954  NUDT5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
102067557  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
102073195  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
102072906  ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
102074462  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
102074588  PPAT; amidophosphoribosyltransferase isoform X1 [KO:K00764] [EC:2.4.2.14]
102071268  LOW QUALITY PROTEIN: trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
102071439  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
102068697  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
102064298  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
102060900  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
102070592  cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
102063772  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
102070103  NT5C2; cytosolic purine 5'-nucleotidase isoform X3 [KO:K01081] [EC:3.1.3.5]
102062669  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
102074562  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
102065572  cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
102072772  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
102065166  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
102065465  LACC1; laccase domain-containing protein 1 isoform X1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
102071657  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
102061014  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
102064583  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
102062474  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
102061231  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
102061405  nucleoside diphosphate kinase A isoform X2 [KO:K00940] [EC:2.7.4.6]
102066627  uncharacterized protein LOC102066627 [KO:K00940] [EC:2.7.4.6]
102067251  AK9; adenylate kinase 9 isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
102066915  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
102072513  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 isoform X1 [KO:K01510] [EC:3.6.1.5]
102065192  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
106629640  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
106629946  soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
102070148  ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
102074278  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
102071276  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
102064540  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
102067540  XDH; xanthine dehydrogenase/oxidase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
106629169  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
102068355  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
102075396  GMPR; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
102073992  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
102072900  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
102074186  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
102061383  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
102066820  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
102064464  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
102072849  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
106630383  PRUNE1; exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
102073009  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
102072826  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
102071169  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
102068664  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
102073757  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
102061077  ADCY8; adenylate cyclase type 8 isoform X2 [KO:K08048] [EC:4.6.1.1]
102065721  ADCY9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
102061096  GUCY1A1; guanylate cyclase soluble subunit alpha-1 [KO:K12318] [EC:4.6.1.2]
102063002  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
102067723  GUCY1B1; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
102063599  guanylate cyclase soluble subunit beta-2 [KO:K12319] [EC:4.6.1.2]
102063950  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
102068585  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
102070321  NPR2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
102063860  atrial natriuretic peptide receptor 2 isoform X1 [KO:K12324] [EC:4.6.1.2]
102074412  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
102064230  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X3 [KO:K13755] [EC:3.1.4.17]
102067075  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
102064846  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
102073232  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
102075209  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3 [KO:K13762] [EC:3.1.4.35]
102063126  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta isoform X1 [KO:K13756] [EC:3.1.4.35]
102069449  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X1 [KO:K13757] [EC:3.1.4.35]
102069334  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform X1 [KO:K13758]
102068489  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
102072761  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
102067731  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
102073057  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
102061316  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X2 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
102072073  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
102070520  ADSSL1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
102068470  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
102062864  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
102072210  AMPD3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
102073397  ADK; adenosine kinase isoform X1 [KO:K00856] [EC:2.7.1.20]
102069815  ADA2; adenosine deaminase 2 isoform X1 [KO:K19572] [EC:3.5.4.4]
102074526  AK7; adenylate kinase 7 isoform X3 [KO:K00939] [EC:2.7.4.3]
102069906  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
102068820  AK1; adenylate kinase isoenzyme 1 isoform X2 [KO:K00939] [EC:2.7.4.3]
102073948  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
102072817  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
102061969  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
102062672  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
102063422  AK3; GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [KO:K00944] [EC:2.7.4.10]
102063676  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
102068880  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
102065298  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
102066618  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
102066208  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [KO:K13293] [EC:3.1.4.53]
102060531  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
102072254  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
102061589  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
102072658  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2 [KO:K18437] [EC:3.1.4.53]
102071221  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
102068151  FHIT; bis(5'-adenosyl)-triphosphatase isoform X1 [KO:K01522] [EC:3.6.1.29]
102064076  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
102067715  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
102065253  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
102068609  uricase isoform X1 [KO:K00365] [EC:1.7.3.3]
102072923  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
zab00030  Pentose phosphate pathway
zab00220  Arginine biosynthesis
zab00250  Alanine, aspartate and glutamate metabolism
zab00260  Glycine, serine and threonine metabolism
zab00340  Histidine metabolism
zab00630  Glyoxylate and dicarboxylate metabolism
zab00730  Thiamine metabolism
zab00740  Riboflavin metabolism
zab00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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