KEGG MEDICUS 疾患情報 |
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| エントリ | 名称 | 概要 | カテゴリ | パスウェイ | 病因遺伝子 |
|---|---|---|---|---|---|
| H00333 | レンサ球菌感染症 | Streptococci are gram-positive bacteria. Among the beta-hemolytic streptococci, Streptococcus pyogenes (Group A streptococci, GAS) and Streptococcus agalactiae (Group B streptococci, GBS) are major human ... | 細菌感染症 | ||
| H00334 | 細菌性心内膜炎 | Infective endocarditis is a microbial infection of the endocardial surface of the heart. The characteristic lesion, a vegetation, is composed of a collection of platelets, fibrin, microorganisms, and inflammatory ... | 細菌感染症 | ||
| H00335 | ウェルシュ菌食中毒 | Clostridium perfringens is a spore-forming, gram-positive, anaerobic bacterium consisting of five types (A-E), according to the major toxins they produce. It causes two different foodborne diseases: Type ... | 細菌感染症 | ||
| H00336 | ガス壊疽 | Gas gangrene is a rare and devastating wound infection. The Clostridium perfringens, septicum, and histolyticum are the principal causes of trauma-associated gas gangrene. It is characterized by fever ... | 細菌感染症 | ||
| H00337 | 破傷風 | Tetanus is a serious, often fatal intoxication caused by infection of Clostridium tetani, a gram-positive bacterium, through cuts or wounds. Mortality rate among untreated patients is high. Tetanus affects ... | 細菌感染症 | ||
| H00338 | 偽膜性大腸炎 | Clostridium difficile is a gram-positive anaerobic bacillus that causes a broad spectrum of clinical symptoms ranging from mild diarrhea to severe pseudomembranous colitis. C. difficile can be transmitted ... | 細菌感染症 | ||
| H00339 | ボツリヌス中毒症 | Botulism is an acute neuroparalytic illness caused by a botulinum toxin produced by Clostridium botulinum, an anaerobic, gram-positive bacterium. Botulism occurs in four forms: foodborne, wound, infant ... | 細菌感染症 | ||
| H00340 | バンコマイシン耐性腸球菌感染症 | Enterococci are gram-positive, facultative bacteria with low intrinsic virulence that constitute the normal colonizing flora of the human gastrointestinal tract. Vancomycin-resistant enterococci (VRE) ... | 細菌感染症 | ||
| H00341 | マイコプラズマ肺炎 | Mycoplasmas represent the smallest self-replicating organisms that are most closely related to the gram-positive bacterial group that includes streptococci, bacilli, and lactobacilli. Mycoplasma pneumoniae ... | 細菌感染症 | ||
| H00342 | 結核 | Tuberculosis is an infectious disease caused by strains of mycobacteria, mainly Mycobacterium tuberculosis, resulting in an estimated two million deaths each year worldwide, more than from any other single ... | 細菌感染症 | hsa05152 Tuberculosis |
IFNG (protection) [HSA:3458] [KO:K04687] IFNGR1 (susceptibility/protection) [HSA:3459] [KO:K05132] IFNGR2 [HSA:3460] [KO:K05133] HLA-DRB1 (susceptibility) [HSA:3123] [KO:K06752] HLA-DQB1 (susceptibility) [HSA:3119] [KO:K06752] SLC11A1 (susceptibility) [HSA:6556] [KO:K12347] VDR (susceptibility) [HSA:7421] [KO:K08539] MBL2 (protection) [HSA:4153] [KO:K03991] CCL2 (susceptibility) [HSA:6347] [KO:K14624] CD209 (susceptibility) [HSA:30835] [KO:K06563] CISH (susceptibility) [HSA:1154] [KO:K04701] IRGM (protection) [HSA:345611] [KO:K14139] SP110 (susceptibility) [HSA:3431] [KO:K24503] TIRAP (protection) [HSA:114609] [KO:K05403] TLR2 (susceptibility) [HSA:7097] [KO:K10159] |
| H00343 | ジフテリア | Diphtheria is a contagious and potentially life-threatening childhood disease caused by Corynebacterium diphtheriae. In industrialized countries, immunization against diphtheria became widespread in the ... | 細菌感染症 | ||
| H00344 | ハンセン病 | Leprosy, also called Hansen's disease, is a chronic infection caused by Mycobacterium leprae (M. leprae) and the more recently discovered Mycobacterium lepromatosis (M. lepromatosis). It primarily affects ... | 細菌感染症 |
(LPRS3) TLR2 [HSA:7097] [KO:K10159] (LPRS4) LTA [HSA:4049] [KO:K05468] (LPRS5) TLR1 [HSA:7096] [KO:K05398] |
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| H00345 | ノカルジア症 | Nocardiosis is an uncommon gram-positive bacterial infection that affects mainly patients with deficient cell-mediated immunity. It has been reported worldwide in all ages and ethnic groups. Pulmonary ... | 細菌感染症 | ||
| H00346 |
外因性アレルギー性肺胞炎 過敏性肺炎 |
Extrinsic allergic alveolitis (EAA), also known as hypersensitivity pneumonitis, is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response ... | 免疫系疾患 | ||
| H00347 |
性器クラミジア感染症 クラミジア性尿道炎 |
Chlamydia trachomatis is a gram-negative, obligate intracellular bacterium that causes the most common sexually transmissible diseases in the world. Chlamydial infection can cause cervicitis in women and ... | 細菌感染症 | ||
| H00348 | 鼠径リンパ肉芽腫 | Chlamydia trachomatis is a gram-negative, obligate intracellular bacterium that causes the most common sexually transmissible diseases in the world. Serovars L1, L2, L2a and L3 of C. trachomatis are the ... | 細菌感染症 | ||
| H00349 | トラコーマ | Trachoma is the leading infectious cause of blindness worldwide. Infections with serovars A, B, Ba, and C of Chlamydia trachomatis cause chronic keratoconjunctivitis in children with subsequent scarring ... | 細菌感染症 | ||
| H00350 | オウム病 | Psittacosis, also known as parrot disease, is an infectious disease caused by Chlamydophila psittaci, a gram-negative intracellular bacterium that is usually transmitted to humans from birds. Symptoms ... | 細菌感染症 | ||
| H00351 | クラミジア肺炎 | Chlamydophila (Cp.) pneumoniae is an obligate intracellular bacteria that causes human respiratory infections. Most acute respiratory infections are asymptomatic or mildly symptomatic. Repeated or prolonged ... | 細菌感染症 | ||
| H00352 | ホイップル病 | Whipple disease (WD) is a rare chronic multi-system disease associated with the bacterium Tropheryma whipplei that is ubiquitously present in the environment. The clinical features of WD are non-specific ... | 細菌感染症 | ||
| H00353 |
ライムボレリア症 ライム病 |
Lyme borreliosis is the multisystem infectious disease caused by the tick-borne spirochetes Borrelia. Localized infection is typically manifested by erythema migrans skin lesions. A broad variety of peripheral ... | 細菌感染症 | ||
| H00354 | 梅毒 | Syphilis is one of the oldest recognized venereal infections caused by the spirochete Treponema pallidum subsp. pallidum. It is characterized by genital ulceration, skin rash, and development of serious ... | 細菌感染症 | ||
| H00355 |
レプトスピラ症 ワイル病 |
Leptospirosis is a zoonosis, caused by pathogenic spirochetes belonging to the genus Leptospira. Many mammalian species and amphibians may act as reservoirs. Leptospira colonize the renal tubules of chronically ... | 細菌感染症 | ||
| H00356 | クリプトスポリジウム症 | Human cryptosporidiosis is a self-limited diarrheal disease characterized by acute, persistent, or chronic diarrhea and biliary/pulmonary disease. Transmission of the causative agent, Cryptosporidium, ... | 寄生虫感染症 | ||
| H00357 | アフリカ睡眠病 | African trypanosomiasis is a parasitic disease affecting both humans and livestock. It is one of the most common serious protozoan infections in sub-Saharan Africa, especially in areas of conflict. Its ... | 寄生虫感染症 | hsa05143 African trypanosomiasis | |
| H00358 | シャーガス病 | Chagas disease, also known as American trypanosomiasis, is caused by infection with protozoan parasite Trypanosoma cruzi. The infection is transmitted by hematophagous reduviid insect vectors through fecal ... | 寄生虫感染症 | hsa05142 Chagas disease | |
| H00359 | リーシュマニア症 | Leishmaniasis is a vector-borne disease that affects millions of people especially in developing countries of Africa, the Americas, and Asia. Leishmaniasis is caused by a protozoan parasite of the genus ... | 寄生虫感染症 | hsa05140 Leishmaniasis | |
| H00360 | アメーバ赤痢 | Amoebiasis is a parasitic disease of gastrointestinal tract caused by Entamoeba histolytica (E. histolytica), an extracellular parasitic protozoan. People living in Central and South America and Africa ... | 寄生虫感染症 | hsa05146 Amoebiasis | |
| H00361 | マラリア | Malaria, the most common parasitic disease in the world, is caused by Plasmodium parasites that are transmitted by female Anopheline mosquitoes. Plasmodium infections result in a spectrum of clinical effects ... | 寄生虫感染症 | hsa05144 Malaria |
ACKR1 (protection) [HSA:2532] [KO:K06574] CD36 (susceptibility/reduced risk) [HSA:948] [KO:K06259] CISH (susceptibility) [HSA:1154] [KO:K04701] CR1 (resistance) [HSA:1378] [KO:K04011] FCGR2A (susceptibility) [HSA:2212] [KO:K06472] FCGR2B (resistance) [HSA:2213] [KO:K12560] G6PD (resistance) [HSA:2539] [KO:K00036] GYPA (resistance) [HSA:2993] [KO:K06575] GYPB (resistance) [HSA:2994] [KO:K20925] GYPC (resistance) [HSA:2995] [KO:K06576] HBB (resistance) [HSA:3043] [KO:K13823] ICAM1 (susceptibility) [HSA:3383] [KO:K06490] NOS2 (resistance) [HSA:4843] [KO:K13241] SLC4A1 (resistance) [HSA:6521] [KO:K06573] TIRAP (protection) [HSA:114609] [KO:K05403] TNF (susceptibility) [HSA:7124] [KO:K03156] |
| H00362 |
ジアルジア症 ランブル鞭毛虫症 |
Giardiasis is one of the most common parasite-induced diarrhea caused by the protozoan parasite Giardia lamblia. Infection is transmitted by ingestion of contaminated water or food, or by person-to-person ... | 寄生虫感染症 |