KEGG    Network variation - Yersinia
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ENTRYnt06183
NameYersinia
CategoryDisease view; Bacterial infection
Pathwayhsa05135 Yersinia infection
DiseaseH00298 Yersiniosis
Display drug-target relation   disease type
Calcium signaling
N01106    (TCR+CD3+CD4)(LCK,FYN,ZAP70)(SLP76+GADS+LAT+VA..PLCGIP3ITPRCa2+(cyto)
N01107    YopHLCK
N01108      YopH(SLP76,LAT,VAV)
 
TLR signaling
N00435    (TLR1,TLR2,TLR4)(TIRAP+MYD88)(IRAK4+IRAK1)(TRAF6+TAK1+TAB2)IKKNFKBIANFKB(TNF,IL6,IL12A,IL1..
N00859        YopP/J(TRAF6+TRAF2+TAK1+..
N00438    (TLR2,TLR4)(TIRAP+MYD88)(IRAK4+IRAK1)(TRAF6+TAK1+TAB2)(MEK,MKK3/6,MKK4/7..(ERK,p38,JNK)AP1
N00862          YopP/J(MEK,MKK3/6,MKK4/7..
 
NLR signaling
N00742      (NLRP3+PYCARD)CASP1(IL1B,IL18,IL33)
N00864    YopK(NLRP3+PYCARD)
N00863      YopMCASP1
N00867      (NLRC4+PYCARD)CASP1(IL1B,IL18)
N00865    YopK(NLRC4+PYCARD)
N01570      PSTPIP1MEFV
N00866    YopM(PKN1,PKN2)(MEFV+PYCARD)
 
Cytoskeletal regulation
N01072    FN1(ITGA+ITGB)PTK2ARHGEF28RHOA
N01098          YopTRHOA
N01099          YopERHOA
N01104    LPALPAR(GNAQ,GNA11)ARHGEF12RHOA
N01105      YpkAGNAQ
N01068    FN1(ITGA+ITGB)(SRC,PTK2)(PXN,CRK+BCAR1)(DOCK1+ELMO1)RAC
N01111      YopHPTK2
N01109        YopHPXN
N01110        YopHBCAR1
N00951    FN1(ITGA+ITGB)RHOG(DOCK1+ELMO)RAC
N01100      YopERHOG
N01101      YopTRHOG
N01102          YopERAC1
N01090    IGGFCGRCRKDOCK1RAC
N01103          YpkARAC