Network variation - Calcium signaling
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Network variation - Calcium signaling
|
| ENTRY | nt06528 |
| Name | Calcium signaling |
| Category | Pathway view; Signal transduction |
| Pathway | hsa04020 Calcium signaling pathway |
| Disease | H00720 Long QT syndrome H00728 Brugada syndrome H01019 Catecholaminergic polymorphic ventricular tachycardia H00293 Arrhythmogenic right ventricular cardiomyopathy H00606 Early infantile epileptic encephalopathy H00063 Spinocerebellar ataxia |
| Display | drug-target relation disease type |
| Disease name | Disease category | ||
| HOKPP1 | H00215 | Periodic paralysis | Nervous system disease |
| CMYP1B | H01810 | Congenital myopathy | Nervous system disease |
| VMCQA | H02320 | Vacuolar myopathy with CASQ1 aggregates | Musculoskeletal disease |
| CMYP13 | H01810 | Congenital myopathy | Nervous system disease |
| LQT8 | H00720 | Long QT syndrome | Cardiovascular disease |
| BRGDA3/NEDHLSS | H00728 | Brugada syndrome | Cardiovascular disease |
| H02856 | Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures | Congenital malformation | |
| CPVT1 | H01019 | Catecholaminergic polymorphic ventricular tachycardia | Cardiovascular disease |
| ARVD2 | H00293 | Arrhythmogenic right ventricular cardiomyopathy | Cardiovascular disease |
| CPVT5 | H01019 | Catecholaminergic polymorphic ventricular tachycardia | Cardiovascular disease |
| CPVT2 | H01019 | Catecholaminergic polymorphic ventricular tachycardia | Cardiovascular disease |
| SCA6/FHM1/SHM1 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| H00775 | Hemiplegic migraine | Nervous system disease | |
| PASNA | H01603 | Primary aldosteronism | Endocrine and metabolic disease |
| DEE69 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| SCA42 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| HALD4/EIG6 | H01603 | Primary aldosteronism | Endocrine and metabolic disease |
| H00808 | Idiopathic generalized epilepsies | Nervous system disease | |
| NEDSIS | H02858 | Neurodevelopmental disorder with speech impairment and with or without seizures | Congenital malformation |
| DEE42/EA2 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| H00749 | Episodic ataxias | Nervous system disease | |
| NEDNEH | H02859 | Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements | Congenital malformation |
| SANDD | H02636 | Sinoatrial node dysfunction and deafness | Cardiovascular disease |
| CSNB2A/CORDX3/AIED | H00787 | Congenital stationary night blindness | Nervous system disease |
| H00481 | Cone-rod dystrophy and cone dystrophy | Nervous system disease | |
| H00690 | Aland Island eye disease | Nervous system disease | |
| DEE46 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| LKS | H01514 | Landau-Kleffner syndrome | Nervous system disease |
| DEE27/MRD6 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder | |
| DEE101/MRD8/NDHMSD/R | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder | |
| H02865 | Neurodevelopmental disorder with or without hyperkinetic movements and seizures | Nervous system disease | |
| DFNA41 | H00604 | Deafness, autosomal dominant | Nervous system disease |
| TAM1/STRMK | H02258 | Tubular aggregate myopathy | Musculoskeletal disease |
| H02259 | Stormorken syndrome | Hematologic disease | |
| IMD10 | H00093 | Combined immunodeficiency | Primary immunodeficiency |
| TAM2 | H02258 | Tubular aggregate myopathy | Musculoskeletal disease |
| IMD9 | H00093 | Combined immunodeficiency | Primary immunodeficiency |
| SCA44/SCAR13 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| H01891 | Autosomal recessive spinocerebellar ataxias | Neurodegenerative disease | |
| DEE58 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| DEE12 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| SCA29 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| SCA15 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| CMT1J | H00264 | Charcot-Marie-Tooth disease | Neurodegenerative disease |
| IMD132 | H00093 | Combined immunodeficiency | Primary immunodeficiency |
| HCC | H00048 | Hepatocellular carcinoma | Cancer |
| Glioma/NSCLC | H00042 | Glioma | Cancer |
| H00014 | Non-small cell lung cancer | Cancer | |
| DFNB97 | H00605 | Deafness, autosomal recessive | Nervous system disease |
| DFNB39 | H00605 | Deafness, autosomal recessive | Nervous system disease |
| ANHD | H02281 | Isolated anhidrosis with normal sweat glands | Skin disease |
| NDNC3 | H01307 | Nonsyndromic congenital nail disorder | Skin disease |
| MLIV | H00144 | Mucolipidosis IV | Inherited metabolic disorder, Lysosomal disease |
| BROD | H01129 | Brody myopathy | Nervous system disease |
| DAR/AKV | H00715 | Darier disease | Congenital malformation |
| H00755 | Acrokeratosis verruciformis | Congenital malformation | |
| CMH18 | H00292 | Hypertrophic cardiomyopathy | Cardiovascular disease |
| CMD1P | H00294 | Dilated cardiomyopathy | Cardiovascular disease |
| DFNA82/DFNB12 | H00604 | Deafness, autosomal dominant | Nervous system disease |
| H00605 | Deafness, autosomal recessive | Nervous system disease | |
| SCAX1 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| ACCIID | H02641 | Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development | Congenital malformation |
| DEE91/IECEE1 | H00606 | Early infantile epileptic encephalopathy | Nervous system disease |
| H02150 | Infantile or early childhood epileptic encephalopathy | Nervous system disease | |
| MRD53 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRD54 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRD59 | H00773 | Autosomal dominant intellectual developmental disorder | Mental and behavioural disorder |
| MRT63 | H00768 | Autosomal recessive intellectual developmental disorder | Mental and behavioural disorder |
| AAT7/MMIHS1 | H00801 | Familial thoracic aortic aneurysm and dissection | Cardiovascular disease |
| H01869 | Megacystis microcolon intestinal hypoperistalsis syndrome | Congenital malformation | |
| CMH1 | H00292 | Hypertrophic cardiomyopathy | Cardiovascular disease |
| LQT14/CPVT4 | H00720 | Long QT syndrome | Cardiovascular disease |
| H01019 | Catecholaminergic polymorphic ventricular tachycardia | Cardiovascular disease | |
| LQT15 | H00720 | Long QT syndrome | Cardiovascular disease |
| LQT16/CPVT6 | H00720 | Long QT syndrome | Cardiovascular disease |
| H01019 | Catecholaminergic polymorphic ventricular tachycardia | Cardiovascular disease | |
| SCA14 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |
| SCA41 | H00063 | Spinocerebellar ataxia (SCA) | Neurodegenerative disease |