KEGG ORTHOLOGY: K22046

ORTHOLOGY: K22046

Entry

K22046                      KO

Symbol

BCL11B

Name

B-cell lymphoma/leukemia 11B

Pathway

map05202

Transcriptional misregulation in cancer

Disease

H00091

T-B+Severe combined immunodeficiency

H02463

Syndromic intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K22046  BCL11B; B-cell lymphoma/leukemia 11B
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K22046  BCL11B; B-cell lymphoma/leukemia 11B
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys2His2 others
    K22046  BCL11B; B-cell lymphoma/leukemia 11B

Genes

HSA:	64919(BCL11B)

PTR:	467548(BCL11B)

PPS:	100989018(BCL11B)

GGO:	101140996(BCL11B)

PON:	100442236(BCL11B)

PPYG:

129013022(BCL11B)

NLE:	100582774(BCL11B)

HMH:	116484991(BCL11B)

SSYN:

129487462(BCL11B)

MCC:	705238(BCL11B)

MCF:	102137024(BCL11B)

MTHB:

126958415

MNI:	105467436(BCL11B)

CSAB:

103229675(BCL11B)

CATY:

105596673(BCL11B)

PANU:

100137584(BCL11B)

TGE:	112628672(BCL11B)

RRO:	104654519(BCL11B)

RBB:	108519069(BCL11B)

TFN:	117071410(BCL11B)

PTEH:

111538285(BCL11B)

CANG:

105518556(BCL11B)

CJC:	100396584(BCL11B)

SBQ:	101032628(BCL11B)

CIMI:

108312337

ANAN:

105730103(BCL11B)

MMUR:

105864077(BCL11B)

LCAT:

123644778(BCL11B)

PCOQ:

105814960(BCL11B)

OGA:	100965611(BCL11B)

MMU:	58208(Bcl11b)

MCAL:

110307082(Bcl11b)

MPAH:

110324287(Bcl11b)

RNO:	314423(Bcl11b)

MCOC:

116080687(Bcl11b)

ANU:	117697445(Bcl11b)

ASYL:

127686967(Bcl11b)

MUN:	110555736(Bcl11b)

CGE:	100768427(Bcl11b)

MAUA:

101836010(Bcl11b)

PROB:

127231126(Bcl11b)

PLEU:

114701898(Bcl11b)

MORG:

121434327(Bcl11b)

MFOT:

126509136

AAMP:

119819408(Bcl11b)

NGI:	103727660(Bcl11b)

HGL:	101712090(Bcl11b)

CPOC:

100728663(Bcl11b)

CCAN:

109677004 109677005

DORD:

105983309(Bcl11b) 105987711

DSP:	122118808(Bcl11b)

DMER:

138810458(Bcl11b)

PLOP:

125363252(Bcl11b)

NCAR:

124978078

MMMA:

107144793(Bcl11b)

ITI:	101959447(Bcl11b)

OCU:

100355589

OPI:	101528400(BCL11B)

OCZ:	121152865(BCL11B)

TUP:	102497751(BCL11B)

CFA:	612476(BCL11B)

CLUD:

112657355(BCL11B)

VVP:	112930240(BCL11B)

VLG:	121493481(BCL11B)

NPO:	129496126(BCL11B)

AML:	100471593(BCL11B)

UMR:	121105206(BCL11B)

UAH:	113267286(BCL11B)

UAR:	123778184(BCL11B)

ELK:

111148678

LLV:

125105249

MPUF:

101679171(BCL11B)

MNP:	132000247(BCL11B)

MLK:	131836972(BCL11B)

NVS:	122893514(BCL11B)

ORO:	101363481(BCL11B)

EJU:	114205807(BCL11B)

ZCA:	113910359(BCL11B)

MLX:	118002234(BCL11B)

NSU:	110571554(BCL11B)

LWW:	102735208(BCL11B)

FCA:	101092121(BCL11B)

PYU:	121032268(BCL11B)

PBG:	122469517(BCL11B)

PVIV:

125168719(BCL11B)

LRUF:

124512533

LGF:	123584296(BCL11B)

AJU:

113601443

PTG:	107180824(BCL11B)

PPAD:

109274390(BCL11B)

PUC:

125909182

PLEZ:

122223113(BCL11B)

HHV:	120245730(BCL11B)

BTA:	783269(BCL11B)

BOM:	102269357(BCL11B)

BIU:	109575724(BCL11B)

BBUB:

102399557(BCL11B)

BBIS:

104997013(BCL11B)

CHX:	102177104(BCL11B)

OAS:	101116868(BCL11B)

BTAX:

128066748(BCL11B)

CSUM:

138095205(BCL11B)

ODA:	120875211(BCL11B)

CCAD:

122454992(BCL11B)

MREE:

136147126(BCL11B)

OVR:	110140576(BCL11B)

MBEZ:

129550638(BCL11B)

SSC:	100154158(BCL11B)

CFR:	102515169(BCL11B)

CBAI:

105080009(BCL11B)

CDK:	105096076(BCL11B)

VPC:	102531715(BCL11B)

BACU:

103012315(BCL11B)

BMUS:

118889543(BCL11B)

LVE:	103069823(BCL11B)

OOR:	101278598(BCL11B)

LALB:

132527605(BCL11B)

GMF:	115867252(BCL11B)

DDP:	132420005(BCL11B)

DLE:	111176097(BCL11B)

PCAD:

102977620(BCL11B)

PSIU:

116749028(BCL11B)

PPHC:

136118075(BCL11B)

NASI:

112408357(BCL11B)

ECB:	100052012(BCL11B)

EPZ:	103550569(BCL11B)

EAI:	106839690(BCL11B)

MYB:	102252726(BCL11B)

MYD:	107183558(BCL11B)

MMYO:

118660236(BCL11B)

MLF:	102424951(BCL11B)

MDT:	132229538(BCL11B)

MYUM:

139008979(BCL11B) 139009806

PKL:	118708811(BCL11B)

EFUS:

103298047(BCL11B)

MNA:	107528075(BCL11B)

DRO:	112311760(BCL11B)

SHON:

118976641(BCL11B)

AJM:	119037885(BCL11B)

PDIC:

114493269(BCL11B)

PHAS:

123808564(BCL11B)

MMF:	118627185(BCL11B)

PPAM:

129065690(BCL11B)

HAI:	109380978(BCL11B)

RFQ:	117024034(BCL11B)

PALE:

102881518(BCL11B)

PGIG:

120619681(BCL11B)

PVP:	105302298(BCL11B)

RAY:	107518574(BCL11B)

MJV:	108397045(BCL11B)

TOD:	119239406(BCL11B)

SARA:

101544587(BCL11B)

SFUM:

130043242(BCL11B)

SETR:

126003633(BCL11B)

LAV:	100653926(BCL11B)

TMU:

101350299

ETF:	101638024(BCL11B)

DNM:	101422759(BCL11B)

MDO:	100023200(BCL11B)

GAS:	123233869(BCL11B)

SHR:	100914768(BCL11B)

AFZ:

127549924

PCW:	110222381(BCL11B)

TVP:	118843698(BCL11B)

PBRV:

138173879 138173925

MLAO:

141506348(BCL11B)

OAA:	100081882(BCL11B)

TACU:

119927861(BCL11B)

GGA:	423444(BCL11B)

PCOC:

116228863(BCL11B)

MGP:	100550178(BCL11B)

CJO:	107315359(BCL11B)

TPAI:

128085647(BCL11B)

LMUT:

125694597(BCL11B)

NMEL:

110401151(BCL11B)

APLA:

101804750(BCL11B)

ACYG:

106036114(BCL11B)

CATA:

118258192(BCL11B)

AFUL:

116489913(BCL11B)

TGU:	100231589(BCL11B)

LSR:	110481179(BCL11B)

SCAN:

103826438(BCL11B)

PMOA:

120503856(BCL11B)

OTC:	121332707(BCL11B)

PRUF:

121358261(BCL11B)

ATRC:

139589792(BCL11B)

GFR:	102043343(BCL11B)

FAB:	101814804(BCL11B)

OMA:	130253920(BCL11B)

PHI:	102100342(BCL11B)

PMAJ:

107205379(BCL11B)

CCAE:

111929545(BCL11B)

CCW:	104686402(BCL11B)

CBRC:

103612229(BCL11B)

ACOE:

138110872(BCL11B)

ETL:	114061691(BCL11B)

ZAB:	102070821(BCL11B)

ZLE:	135448893(BCL11B)

ACHL:

103810337(BCL11B)

SVG:	106850569(BCL11B)

MMEA:

130576914(BCL11B)

HRT:	120754271(BCL11B)

SATI:

136362916(BCL11B)

CCIC:

134045684(BCL11B)

FPG:	101917965(BCL11B)

FCH:	102045966(BCL11B)

CCRI:

104155153(BCL11B)

NNT:	104413779(BCL11B)

SHAB:

115606273(BCL11B)

ACUN:

113480443 113480444

TALA:

104361252(BCL11B)

ACHC:

115336541(BCL11B)

HALD:

104318470(BCL11B)

HLE:	104841906(BCL11B)

AGEN:

126050694

HHAR:

128139947(BCL11B)

GCL:

127016948

CSTI:

104560923

LDI:	104340349(BCL11B)

MNB:	103771404(BCL11B)

DPUB:

104304513(BCL11B)

PPUS:

135173817(BCL11B)

AVIT:

104270996(BCL11B)

BRHI:

104499088(BCL11B)

EGZ:	104127788(BCL11B)

NNI:	104014831(BCL11B)

PCRI:

104031591(BCL11B)

PCAO:

104049972

PADL:

103915672(BCL11B)

AFOR:

103900310(BCL11B)

FGA:	104073275(BCL11B)

CBOR:

142082739(BCL11B)

GSTE:

104254182(BCL11B)

CBOY:

140653099(BCL11B)

MAME:

142409785(BCL11B)

CLV:	102089123(BCL11B)

CNIC:

135989191(BCL11B)

MUI:	104540851(BCL11B)

PGUU:

104469315(BCL11B)

PLET:

104613647(BCL11B)

EHS:	104503434(BCL11B)

CMAC:

104476018(BCL11B)

CUCA:

104057750(BCL11B)

TEO:	104378500(BCL11B)

BREG:

104634692(BCL11B)

OHA:	104331562(BCL11B)

ACAR:

104517506(BCL11B)

CPEA:

104389070(BCL11B)

CVF:	104291786(BCL11B)

RTD:	128909124(BCL11B)

CRID:

134514700(BCL11B)

LMIC:

141742245(BCL11B)

AAM:	106483082(BCL11B)

AROW:

112972679(BCL11B)

NPD:	112956961(BCL11B)

TGT:	104574148(BCL11B)

DNE:	112989925(BCL11B)

SCAM:

104144443(BCL11B)

ASN:	102382803(BCL11B)

AMJ:	102558585(BCL11B)

CPOO:

109321739(BCL11B)

GGN:	109298470(BCL11B)

PSS:	102446690(BCL11B)

CIZ:	142015279(BCL11B)

CMY:	102936140(BCL11B)

CCAY:

125638433(BCL11B)

DCC:	119857911(BCL11B)

CPIC:

101952797(BCL11B)

TST:	117876486(BCL11B)

CABI:

116820941(BCL11B)

MRV:	120404479(BCL11B)

ACS:	100564891(bcl11b)

ASAO:

132762626(BCL11B)

PVT:	110088867(BCL11B)

SUND:

121919171(BCL11B)

PBI:	103061374(BCL11B)

PMUR:

107291242 107291248

CTIG:

120306453(BCL11B)

TSR:	106543999(BCL11B)

PGUT:

117665969(BCL11B)

PCAE:

139308105(BCL11B)

APRI:

131187901(BCL11B)

PTEX:

113447003(BCL11B)

NSS:	113419820(BCL11B)

VKO:	123026672(BCL11B)

PMUA:

114589119(BCL11B)

PRAF:

128407245(BCL11B)

ZVI:	118080720(BCL11B)

HCG:	128329623(BCL11B)

GJA:	107118194(BCL11B)

STOW:

125426714(BCL11B)

EMC:	129323888(BCL11B)

XLA:	108698742(bcl11b.L) 108699805(bcl11b.S)

XTR:	100486647(bcl11b)

NPR:	108786869(BCL11B)

RTEM:

120920859(BCL11B)

ACAT:

141117500(BCL11B)

BBUF:

120982414(BCL11B)

BGAR:

122921815(BCL11B)

DTC:	141091911(BCL11B)

PWL:	138259808(ZNF296) 138260117(BCL11B)

MUO:	115478121(BCL11B)

GSH:	117363877(BCL11B)

DRE:	100093707(bcl11ba) 100330974(bcl11bb)

SRX:	107740616 107742200

SANH:

107668592 107678676 107679682 107680755

SGH:	107555305 107560207 107583625 107588284

CCAR:

109098976 109099293 109108078 122148935

CAUA:

113063423 113094542 113117422 113121248

CGIB:

127933377 127938790 127976365 127984288

PTET:

122325122(bcl11bb) 122361998(bcl11ba)

LROH:

127179776(bcl11ba) 127183019(bcl11bb)

GRF:	141283277(bcl11bb) 141295561(bcl11ba)

OMC:	131523301(bcl11ba) 131527273(bcl11bb)

PPRM:

120478866(bcl11ba) 120493990(bcl11bb)

RKG:	130070616(bcl11ba) 130096026(bcl11bb)

MAMB:

125268524(bcl11ba) 125277793(bcl11bb)

CIDE:

127498792 127502559

CERY:

137007079(bcl11ba) 137018684(bcl11bb)

MASI:

127410293 127411562 127415796 127454827

TROS:

130559976(bcl11ba) 130566454(bcl11bb)

TDW:	130434871(bcl11bb) 130437049(bcl11ba)

MANU:

129417726(bcl11ba) 129429588(bcl11bb)

PDAB:

135733377(bcl11ba) 135750023(bcl11bb)

IPU:	108258024(bcl11bb) 108270293(bcl11ba)

IFU:	128601102(bcl11bb) 128612387(bcl11ba)

PHYP:

113532115 113534195(bcl11b)

SMEO:

124376973(bcl11bb) 124390499(bcl11ba)

TFD:	113648309(bcl11bb) 113651150(bcl11ba)

TVC:	132843130(bcl11bb) 132852948(bcl11ba)

CGAR:

128515096(bcl11bb) 128535939(bcl11ba)

NGRA:

132883885(bcl11bb) 132894203(bcl11ba)

TRN:	134320492(bcl11bb) 134324979(bcl11ba)

AMEX:

103027528(bcl11bb) 103041578(bcl11ba)

CMAO:

118815783(bcl11bb) 118823735(bcl11ba)

EEE:	113569951 113579783

CHAR:

105901418(bcl11bb) 105908268(bcl11ba)

SPIL:

134067670(bcl11ba) 134098017(bcl11bb)

ASAD:

121693013(bcl11ba) 121712330(bcl11bb)

TRU:	101062778 101067361

TFS:	130516603(bcl11bb) 130540012(bcl11ba)

TNG:	GSTEN00015769G001 GSTEN00018407G001

LCO:	104926960 104936075

NCC:	104950373 104967181(bcl11b)

TBEN:

117486344(bcl11ba) 117498390(bcl11bb)

CGOB:

115003679 115027353

PGEO:

117440169(bcl11bb) 117442730(bcl11ba)

GACU:

117533334(bcl11ba) 117554318(bcl11bb)

EMAC:

134877023(bcl11bb) 134881841(bcl11ba)

ELY:	117266562(bcl11ba) 117270898(bcl11bb)

EFO:	125897065(bcl11bb) 125900939(bcl11ba)

PLEP:

121953477(bcl11ba) 121955084

SLUC:

116036759(bcl11ba) 116041988(bcl11bb)

ECRA:

117935825(bcl11ba) 117961563(bcl11bb)

ESP:	116670191(bcl11b) 116706503

PFLV:

114547371(bcl11b) 114573395

GAT:	120808144 120832915(bcl11ba)

PPUG:

119195010(bcl11bb) 119227503(bcl11ba)

AFB:	129103650(bcl11ba) 129106872(bcl11bb)

CLUM:

117725328(bcl11ba) 117727533(bcl11bb)

PSWI:

130191130(bcl11ba) 130191281(bcl11bb)

CANA:

137785727(bcl11bb) 137798601(bcl11ba)

CVE:	137871057(bcl11bb) 137877665(bcl11ba)

MSAM:

119909131(bcl11bb) 119910705(bcl11ba)

SCHU:

122861773(bcl11ba) 122863263(bcl11bb)

CUD:	121520880(bcl11bb) 121525876(bcl11ba)

SPUL:

138591000(bcl11ba) 138612824(bcl11bb)

LMIX:

132985234(bcl11bb) 132993812(bcl11ba)

HTC:	141801932(bcl11bb) 141806569(bcl11ba)

ALAT:

119005097(bcl11ba) 119012893(bcl11bb)

ASTR:

137611431(bcl11ba) 137613379(bcl11bb)

MZE:	101482479 101487117(bcl11b)

ONL:	100697101(bcl11b) 100703242

OAU:	116318048(bcl11ba) 116332305

OLA:	101155396 101169989(bcl11b)

OML:	112145662(bcl11ba) 112158255(bcl11bb)

CSAI:

133462224(bcl11ba) 133464476(bcl11bb)

XMA:	102225842 102226220(bcl11b)

XCO:	114133887(bcl11b) 114158278

XHE:	116708557(bcl11b) 116733674

PRET:

103457828 103458976(bcl11b)

PFOR:

103136309 103138752(bcl11b) 103147691

PLAI:

106939368 106954740(bcl11b) 106956896

PMEI:

106916234 106927228 106932141(bcl11b)

GAF:	122825707(bcl11bb) 122845934(bcl11ba)

PPRL:

129365628(bcl11ba) 129368954(bcl11bb)

CVG:	107081923 107097485 107103218(bcl11b)

CTUL:

119784185(bcl11bb) 119787042(bcl11ba)

GMU:	124855409(bcl11ba) 124882031(bcl11bb)

NFU:	107378147 107396391(bcl11b)

KMR:	108231853(bcl11bb) 108240895(znf296) 108245053(bcl11ba)

ALIM:

106519980(bcl11b) 106525462

NWH:	119411264(znf296) 119418454(bcl11bb) 119427559(bcl11ba)

AOCE:

111563583(bcl11bb) 111563634(bcl11ba)

EJA:	138199151 138203612(bcl11bb)

BFRE:

138614864(bcl11ba) 138623565(bcl11bb)

MCEP:

124999042(bcl11bb) 125023613(bcl11ba)

CSEM:

103380708 103387899(bcl11b)

POV:	109632349 109639543(bcl11b)

SSEN:

122783122(bcl11ba) 122783985

SSOE:

131443697(bcl11bb) 131444355(bcl11ba)

HHIP:

117755774(bcl11ba) 117758426(bcl11bb)

HSP:	118099721(bcl11bb) 118117014(bcl11ba)

PPLT:

128451567(bcl11ba) 128460283(bcl11bb)

SMAU:

118286104(bcl11ba) 118290203(bcl11bb)

LCF:	108897906 108898062(bcl11bb)

SDU:	111226117 111236514

SLAL:

111667261(bcl11b) 111672726

XGL:	120789051(bcl11bb) 120795011(bcl11ba)

HCQ:

109523475

SSCV:

125990408(bcl11bb)

SBIA:

133496515(bcl11bb)

PEE:	133416804(bcl11bb)

PTAO:

133468363(bcl11bb)

BPEC:

110159368 110161283

ENY:	140359711(bcl11bb) 140370142(bcl11ba)

MALB:

109962266 109969060(bcl11b)

BSPL:

114848487(bcl11ba) 114849372(bcl11bb)

SJO:	128375173(bcl11ba) 128376993(bcl11bb)

SSCO:

133997583(bcl11bb) 134000628(bcl11ba)

TTY:	137169251(bcl11bb) 137199479(bcl11ba)

GMH:	115534379 115543843

SASA:

106571106 106601761 106608246 106611254

STRU:

115172322 115175115 115191177

OTW:	112218026 112229227 112233394(bcl11ba) 112239410

OMY:	110497651(bcl11ba) 110510947 110522576 110529319

OGO:	123990515 123995397 124001364(bcl11ba) 124046658

ONE:	115107520 115121157 115121470

OKI:	109866442 109882419 109882422(bcl11b) 109882572

OKE:	118362772(bcl11ba) 118373377 118377963

OMM:	135506221 135507951(bcl11ba) 135525626 135557927

OCLA:

139375022 139383744 139407387 139414914

SALP:

111968981 112072946 112075968 112077691

SNH:	120024260 120039991 120040750 120060053(bcl11ba)

SFON:

129812047(bcl11ba) 129812831 129817897 129825500(bcl11bb)

CCLU:

121539549(bcl11ba) 121544681 121548513 121552219

ELS:	105024351 105024726(bcl11b)

OEP:	134024620(bcl11bb) 134026783(bcl11ba)

SFM:	108919412(bcl11b) 108920392

PKI:	111850952(bcl11b) 111852650

AANG:

118229252 118231094(bcl11ba)

AROT:

135248050(bcl11ba) 135257000

CCOG:

133128126 133129586(bcl11ba)

LOC:	102694091(bcl11b)

PSPA:

121324416 121329847

ARUT:

117395341 117414914 117419657 117422375

PSEX:

120518857(bcl11ba)

LCM:	102363374(BCL11B)

CMK:	103186098(bcl11ba)

RTP:	109930965(bcl11ba)

CPLA:

122542784 122553411(bcl11ba)

HOC:	132818392 132836719

SCAU:

119957819(znf296) 119979372(bcl11ba)

LERI:

129699983(bcl11ba)

HAKA:

140724725(bcl11ba) 140737404(znf296)

PMRN:

116939716(BCL11A)

LRJ:	133347363(BCL11A)

BBEL:

109464880

CIN:	100169982(zf(c2h2)-80)

LPIC:

LVG:

ARUN:

AAMU:

APLN:

HHAL:

CVS:

SDM:

LPOL:

106458314 106460077 106461866

LSAX:

BGT:

CVN:

MMER:

RPHI:

MAEA:

OSN:

LJP:

SMM:	Smp_124090

LLON:

135484225

GLZ:	GLAREA_04361

» show all

Reference

PMID:11719382

Authors

Satterwhite E, Sonoki T, Willis TG, Harder L, Nowak R, Arriola EL, Liu H, Price HP, Gesk S, Steinemann D, Schlegelberger B, Oscier DG, Siebert R, Tucker PW, Dyer MJ

Title

The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.

Journal

Blood 98:3413-20 (2001)
DOI:10.1182/blood.V98.12.3413

Sequence

[hsa:64919]

LinkDB

DBGET integrated database retrieval system