KEGG   REACTION: R08355
Entry
R08355                      Reaction                               
Name
glutathione:glutathionylaminopropylcadaverine ligase (ADP-forming)
Definition
ATP + Glutathione + Glutathionylaminopropylcadaverine <=> ADP + Orthophosphate + Homotrypanothione
Equation
C00002 + C00051 + C16566 <=> C00008 + C00009 + C16567
Reaction class
RC00002  C00002_C00008
RC00090  C00051_C16567
RC00096  C16566_C16567
Enzyme
6.3.1.9
Pathway
rn00480  Glutathione metabolism
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.1  Acid-D-ammonia (or amine) ligases (amide synthases)
    6.3.1.9
     R08355  ATP + Glutathione + Glutathionylaminopropylcadaverine <=> ADP + Orthophosphate + Homotrypanothione
Orthology
K01833  trypanothione synthetase/amidase [EC:6.3.1.9 3.5.1.-]
LinkDB

KEGG   RCLASS: RC00096
Entry
RC00096                     RClass                                 
Definition
N1a-N1b:*-C5a:C1b-C1b
Reactant pair
C00037_C00051    C00037_C01419    C00037_C01586
C00037_C01921    C00037_C02055    C00037_C02564
C00037_C05380    C00037_C05464    C00037_C05466
C00037_C05596    C00037_C05598    C00037_C05729
C00037_C05951    C00037_C16623    C00037_C21016
C00047_C02427    C00047_C02444    C00047_C02727
C00047_C04211    C00047_C05552    C00047_C20278
C00047_C21730    C00077_C00327    C00099_C00864
C00099_C01073    C00099_C02642    C00099_C03492
C00099_C04544    C00134_C00436    C00134_C02714
C00134_C03002    C00134_C10497    C00134_C15699
C00134_C18326    C00179_C02253    C00179_C04498
C00179_C18325    C00189_C04080    C00189_C11695
C00245_C05122    C00245_C05463    C00245_C05465
C00245_C05844    C00315_C01029    C00315_C05730
C00334_C02946    C00334_C15767    C00388_C04138
C00388_C05135    C00431_C03087    C00437_C15532
C00483_C02717    C00483_C20926    C00515_C22101
C00739_C19720    C00750_C16562    C00780_C00978
C00797_C01047    C00825_C03154    C00831_C01678
C01142_C21604    C01205_C21029    C01255_C02378
C01997_C02415    C02038_C03881    C02090_C05730
C02188_C20743    C02188_C21178    C02297_C03687
C02801_C03357    C03194_C06508    C03239_C05548
C03283_C06442    C03318_C04149    C03401_C04209
C03401_C20961    C03401_C22072    C03415_C18048
C03557_C05683    C03557_C21403    C04122_C06509
C04681_C04735    C04682_C04736    C04702_C04894
C04727_C04763    C04801_C04827    C05332_C06746
C05670_C06114    C05771_C05774    C05893_C17550
C05894_C17541    C05895_C17542    C06249_C06250
C06664_C17377    C06866_C16666    C15534_C15535
C16562_C16563    C16565_C16566    C16566_C16567
C16631_C16632    C17399_C20816    C17541_C17542
C17586_C18005    C18007_C18008    C20814_C20816
 » show all
Related class
Reaction
R00059 R00395 R00454 R00458 R00497 R00545 R00665 R00899
R00905 R00909 R01077 R01152 R01154 R01156 R01396 R01398
R01399 R01424 R01425 R01617 R01620 R01687 R01723 R01889
R01917 R01918 R01944 R01987 R02041 R02152 R02276 R02385
R02452 R02473 R02474 R02741 R02797 R02911 R02929 R02930
R02973 R03095 R03552 R03579 R03718 R03720 R03760 R03822
R03910 R03956 R03971 R03975 R03977 R03992 R04056 R04174
R04192 R04211 R04252 R04486 R04487 R04562 R04563 R04582
R04604 R04613 R04666 R04777 R04951 R04975 R05055 R05145
R05226 R05835 R05841 R06529 R06978 R07245 R07300 R07301
R07302 R07414 R07419 R07643 R08228 R08252 R08350 R08351
R08352 R08353 R08354 R08355 R08744 R08745 R08776 R08777
R08778 R08779 R08906 R08910 R08937 R09255 R09256 R09257
R09379 R09536 R09596 R10011 R10633 R10634 R10745 R10746
R10752 R10821 R10902 R10940 R10994 R11207 R11208 R11479
R11701 R11862 R12308 R12353 R12514 R12626
 » show all
Enzyme
2.1.3.3         2.1.3.6         2.1.3.8         2.1.3.9         
2.1.3.11        2.3.1.13        2.3.1.32        2.3.1.48        
2.3.1.57        2.3.1.58        2.3.1.64        2.3.1.65        
2.3.1.71        2.3.1.82        2.3.1.87        2.3.1.97        
2.3.1.108       2.3.1.110       2.3.1.138       2.3.1.178       
2.3.1.192       2.3.1.264       2.3.1.280       2.3.1.286       
2.3.1.306       2.3.1.-         2.3.2.2         2.3.2.10        
2.3.2.15        2.3.2.16        2.3.2.17        2.3.2.18        
2.3.2.35        2.3.2.-         3.4.11.1        3.4.11.2        
3.4.11.23       3.4.13.23       3.4.13.-        3.5.1.6         
3.5.1.12        3.5.1.17        3.5.1.20        3.5.1.21        
3.5.1.22        3.5.1.24        3.5.1.32        3.5.1.40        
3.5.1.46        3.5.1.48        3.5.1.51        3.5.1.53        
3.5.1.60        3.5.1.62        3.5.1.63        3.5.1.65        
3.5.1.71        3.5.1.74        3.5.1.78        3.5.1.85        
3.5.1.90        3.5.1.92        3.5.1.94        3.5.1.99        
3.5.1.119       3.5.1.-         4.3.2.6         4.3.2.8         
6.2.1.39        6.3.1.6         6.3.1.8         6.3.1.9         
6.3.1.10        6.3.1.11        6.3.1.19        6.3.2.1         
6.3.2.3         6.3.2.18        6.3.2.20        6.3.2.23        
6.3.2.36        6.3.2.37        6.3.2.44        6.3.2.46        
6.3.2.54        6.3.2.58        6.3.2.59        6.3.4.9         
6.3.4.10        6.3.4.11        6.3.4.15        6.3.4.24
 » show all
Pathway
rn00120  Primary bile acid biosynthesis
rn00220  Arginine biosynthesis
rn00240  Pyrimidine metabolism
rn00260  Glycine, serine and threonine metabolism
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn00330  Arginine and proline metabolism
rn00332  Carbapenem biosynthesis
rn00340  Histidine metabolism
rn00380  Tryptophan metabolism
rn00410  beta-Alanine metabolism
rn00430  Taurine and hypotaurine metabolism
rn00440  Phosphonate and phosphinate metabolism
rn00460  Cyanoamino acid metabolism
rn00480  Glutathione metabolism
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00550  Peptidoglycan biosynthesis
rn00680  Methane metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00780  Biotin metabolism
rn00860  Porphyrin metabolism
rn00930  Caprolactam degradation
rn00983  Drug metabolism - other enzymes
rn00996  Biosynthesis of various alkaloids
rn00997  Biosynthesis of various other secondary metabolites
rn00998  Biosynthesis of various antibiotics
rn00999  Biosynthesis of various plant secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
RModule
RM024  Pyrimidine degradation
Orthology
K00611  ornithine carbamoyltransferase [EC:2.1.3.3]
K00628  glycine N-acyltransferase / glycine N-benzoyltransferase [EC:2.3.1.13 2.3.1.71]
K00657  diamine N-acetyltransferase [EC:2.3.1.57]
K00659  bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K00669  arylalkylamine N-acetyltransferase [EC:2.3.1.87]
K00681  gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K01255  leucyl aminopeptidase [EC:3.4.11.1]
K01256  aminopeptidase N [EC:3.4.11.2]
K01270  dipeptidase D [EC:3.4.13.-]
K01431  beta-ureidopropionase [EC:3.5.1.6]
K01435  biotinidase [EC:3.5.1.12]
K01442  choloylglycine hydrolase [EC:3.5.1.24]
K01451  hippurate hydrolase [EC:3.5.1.32]
K01453  6-aminohexanoate-oligomer exohydrolase [EC:3.5.1.46]
K01460  glutathionylspermidine amidase/synthetase [EC:3.5.1.78 6.3.1.8]
K01833  trypanothione synthetase/amidase [EC:6.3.1.9 3.5.1.-]
K01917  glutathionylspermidine synthase [EC:6.3.1.8]
K01918  pantoate--beta-alanine ligase [EC:6.3.2.1]
K01920  glutathione synthase [EC:6.3.2.3]
K01942  biotin---protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]
K01947  biotin---[acetyl-CoA-carboxylase] ligase / type III pantothenate kinase [EC:6.3.4.15 2.7.1.33]
K02225  cobalamin biosynthesis protein CobC
K02227  adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
K03524  BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
K05363  serine/alanine adding enzyme [EC:2.3.2.10]
K06016  beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
K06718  L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178]
K06914  tyramine---L-glutamate ligase [EC:6.3.4.24]
K07751  PepB aminopeptidase [EC:3.4.11.23]
K08069  pantetheine hydrolase [EC:3.5.1.92]
K08260  adenosylcobinamide hydrolase [EC:3.5.1.90]
K09065  N-acetylornithine carbamoyltransferase [EC:2.1.3.9]
K09470  gamma-glutamylputrescine synthase [EC:6.3.1.11]
K09473  gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
K09722  4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
K09994  (aminoalkyl)phosphonate N-acetyltransferase [EC:2.3.1.280]
K11121  NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
K11140  aminopeptidase N [EC:3.4.11.2]
K11142  cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11411  NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11412  NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
K11413  NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K11414  NAD-dependent protein deacetylase/lipoamidase sirtuin 4 [EC:2.3.1.286 2.3.1.313]
K11415  NAD-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
K11416  NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K11417  NAD-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286]
K11693  peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16]
K11694  peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17]
K11695  peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18]
K12251  N-carbamoylputrescine amidase [EC:3.5.1.53]
K12410  NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
K13043  N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11]
K13559  [BtrI acyl-carrier protein]--L-glutamate ligase [EC:6.2.1.39]
K13564  gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase [EC:4.3.2.6]
K13571  proteasome accessory factor A [EC:6.3.1.19]
K13799  pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25]
K14329  agmatine coumaroyltransferase [EC:2.3.1.64 2.3.1.-]
K15428  Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
K15517  glycine N-phenylacetyltransferase [EC:2.3.1.192]
K16181  3-methylornithine--L-lysine ligase [EC:6.3.2.59]
K18566  N-acetyltransferase [EC:2.3.1.-]
K18572  putative pantetheine hydrolase [EC:3.5.1.-]
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18854  acetyl-CoA:lysine N6-acetyltransferase [EC:2.3.1.306]
K21456  glutathione synthase [EC:6.3.2.3]
K21935  beta-lysine N6-acetyltransferase [EC:2.3.1.264]
K22113  fumarate---(S)-2,3-diaminopropanoate ligase [EC:6.3.2.46]
K22450  aralkylamine N-acetyltransferase [EC:2.3.1.87]
K23372  L-2,3-diaminopropanoate---citrate ligase [EC:6.3.2.54]
K23446  D-ornithine---citrate ligase [EC:6.3.2.58]
K24277  capsaicin synthase [EC:2.3.2.35]

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