Homo sapiens (human): 2554 Help Entry 2554              CDS       T01001                                  Symbol GABRA1, DEE19, ECA4, EIEE19, EJM, EJM5 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit alpha1   KO K05175   gamma-aminobutyric acid receptor subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa04742   Taste transduction hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy H00808   Idiopathic generalized epilepsies H02215   Childhood absence epilepsy H02217   Juvenile myoclonic epilepsy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clomethiazole (DG00923):  D07330 D07725 Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Etomidate:  D00548<US> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methohexital (DG00789):  D00712<US> D04985 Methylphenobarbital:  D00700 Methyprylon:  D01150 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Progabide:  D05621 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zaleplon:  D00530<US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2554 (GABRA1)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2554 (GABRA1)    04723 Retrograde endocannabinoid signaling     2554 (GABRA1)   09157 Sensory system    04742 Taste transduction     2554 (GABRA1)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2554 (GABRA1)    05033 Nicotine addiction     2554 (GABRA1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2554 (GABRA1) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2554 (GABRA1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2554 NCBI-ProteinID:  NP_000797 OMIM:  137160 HGNC:  4075 Ensembl:  ENSG00000022355 Vega:  OTTHUMG00000163586 Pharos:  P14867(Tclin) UniProt:  P14867 A8K177 LinkDB All DBs Structure PDB:  6I53 5O8F 6D6T 6D6U Thumbnails Position 5q34 AA seq 456 aa AA seqDB search MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ NT seq 1371 nt NT seq  +upstreamnt  +downstreamnt atgaggaaaagtccaggtctgtctgactgtctttgggcctggatcctccttctgagcaca ctgactggaagaagctatggacagccgtcattacaagatgaacttaaagacaataccact gtcttcaccaggattttggacagactcctagatggttatgacaatcgcctgagaccagga ttgggagagcgtgtaaccgaagtgaagactgatatcttcgtcaccagtttcggacccgtt tcagaccatgatatggaatatacaatagatgtatttttccgtcaaagctggaaggatgaa aggttaaaatttaaaggacctatgacagtcctccggttaaataacctaatggcaagtaaa atctggactccggacacatttttccacaatggaaagaagtcagtggcccacaacatgacc atgcccaacaaactcctgcggatcacagaggatggcaccttgctgtacaccatgaggctg acagtgagagctgaatgtccgatgcatttggaggacttccctatggatgcccatgcttgc ccactaaaatttggaagttatgcttatacaagagcagaagttgtttatgaatggaccaga gagccagcacgctcagtggttgtagcagaagatggatcacgtctaaaccagtatgacctt cttggacaaacagtagactctggaattgtccagtcaagtacaggagaatatgttgttatg accactcatttccacttgaagagaaagattggctactttgttattcaaacatacctgcca tgcataatgacagtgattctctcacaagtctccttctggctcaacagagagtctgtacca gcaagaactgtctttggagtaacaactgtgctcaccatgacaacattgagcatcagtgcc agaaactccctccctaaggtggcttatgcaacagctatggattggtttattgccgtgtgc tatgcctttgtgttctcagctctgattgagtttgccacagtaaactatttcactaagaga ggttatgcatgggatggcaaaagtgtggttccagaaaagccaaagaaagtaaaggatcct cttattaagaaaaacaacacttacgctccaacagcaaccagctacacccctaatttggcc aggggcgacccgggcttagccaccattgctaaaagtgcaaccatagaacctaaagaggtc aagcccgaaacaaaaccaccagaacccaagaaaacctttaacagtgtcagcaaaattgac cgactgtcaagaatagccttcccgctgctatttggaatctttaacttagtctactgggct acgtatttaaacagagagcctcagctaaaagcccccacaccacatcaatag

Homo sapiens (human): 2555 Help Entry 2555              CDS       T01001                                  Symbol GABRA2, DEE78, EIEE78 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit alpha2   KO K05175   gamma-aminobutyric acid receptor subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa04742   Taste transduction hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy H01611   Alcohol dependence Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2555 (GABRA2)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2555 (GABRA2)    04723 Retrograde endocannabinoid signaling     2555 (GABRA2)   09157 Sensory system    04742 Taste transduction     2555 (GABRA2)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2555 (GABRA2)    05033 Nicotine addiction     2555 (GABRA2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2555 (GABRA2) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2555 (GABRA2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb CytochromB561_N Motif Other DBs NCBI-GeneID:  2555 NCBI-ProteinID:  NP_000798 OMIM:  137140 HGNC:  4076 Ensembl:  ENSG00000151834 Vega:  OTTHUMG00000044266 Pharos:  P47869(Tclin) UniProt:  P47869 A0A024R9X6 LinkDB All DBs Structure PDB:  5O8F Thumbnails Position 4p12 AA seq 451 aa AA seqDB search MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM SRIVFPVLFGTFNLVYWATYLNREPVLGVSP NT seq 1356 nt NT seq  +upstreamnt  +downstreamnt atgaagacaaaattgaacatctacaacatgcagttcctgctttttgttttcttggtgtgg gaccctgccaggttggtgctggctaacatccaagaagatgaggctaaaaataacattacc atctttacgagaattcttgacagacttctggatggttacgataatcggcttagaccagga ctgggagacagtattactgaagtcttcactaacatctacgtgaccagttttggccctgtc tcagatacagatatggaatatacaattgatgttttctttcgacaaaaatggaaagatgaa cgtttaaaatttaaaggtcctatgaatatccttcgactaaacaatttaatggctagcaaa atctggactccagataccttttttcacaatgggaaaaaatcagtagctcataatatgaca atgccaaataagttgcttcgaattcaggatgatgggactctgctgtataccatgaggctt acagttcaagctgaatgcccaatgcacttggaggatttcccaatggatgctcattcatgt cctctgaaatttggcagctatgcatatacaacttcagaggtcacttatatttggacttac aatgcatctgattcagtacaggttgctcctgatggctctaggttaaatcaatatgacctg ctgggccaatcaatcggaaaggagacaattaaatccagtacaggtgaatatactgtaatg acagctcatttccacctgaaaagaaaaattgggtattttgtgattcaaacctatctgcct tgcatcatgactgtcattctctcccaagtttcattctggcttaacagagaatctgtgcct gcaagaactgtgtttggagtaacaactgtcctaacaatgacaactctaagcatcagtgct cggaattctctccccaaagtggcttatgcaactgccatggactggtttattgctgtttgt tatgcatttgtgttctctgccctaattgaatttgcaactgttaattacttcaccaaaaga ggatgggcttgggatgggaagagtgtagtaaatgacaagaaaaaagaaaaggcttccgtt atgatacagaacaacgcttatgcagtggctgttgccaattatgccccgaatctttcaaaa gatccagttctctccaccatctccaagagtgcaaccacgccagaacccaacaagaagcca gaaaacaagccagctgaagcaaagaaaactttcaacagtgttagcaaaattgacagaatg tccagaatagtttttccagttttgtttggtacctttaatttagtttactgggctacatat ttaaacagagaacctgtattaggggtcagtccttga

Homo sapiens (human): 2556 Help Entry 2556              CDS       T01001                                  Symbol GABRA3 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit alpha3   KO K05175   gamma-aminobutyric acid receptor subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa04742   Taste transduction hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2556 (GABRA3)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2556 (GABRA3)    04723 Retrograde endocannabinoid signaling     2556 (GABRA3)   09157 Sensory system    04742 Taste transduction     2556 (GABRA3)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2556 (GABRA3)    05033 Nicotine addiction     2556 (GABRA3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2556 (GABRA3) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2556 (GABRA3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2556 NCBI-ProteinID:  NP_000799 OMIM:  305660 HGNC:  4077 Ensembl:  ENSG00000011677 Vega:  OTTHUMG00000024183 Pharos:  P34903(Tclin) UniProt:  P34903 LinkDB All DBs Structure PDB:  5O8F Thumbnails Position Xq28 AA seq 492 aa AA seqDB search MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN RESAIKGMIRKQ NT seq 1479 nt NT seq  +upstreamnt  +downstreamnt atgataatcacacaaacaagtcactgttacatgaccagccttgggattcttttcctgatt aatattctccctggaaccactggtcaaggggaatcaagacgacaagaacccggggacttt gtgaagcaggacattggcgggctgtctcctaagcatgccccagatattcctgatgacagc actgacaacatcactatcttcaccagaatcttggatcgtcttctggacggctatgacaac cggctgcgacctgggcttggagatgcagtgactgaagtgaagactgacatctacgtgacc agttttggccctgtgtcagacactgacatggagtacactattgatgtattttttcggcag acatggcatgatgaaagactgaaatttgatggccccatgaagatccttccactgaacaat ctcctggctagtaagatctggacaccggacaccttcttccacaatggcaagaaatcagtg gctcataacatgaccacgcccaacaagctgctcagattggtggacaacggaaccctcctc tatacaatgaggttaacaattcatgctgagtgtcccatgcatttggaagattttcccatg gatgtgcatgcctgcccactgaagtttggaagctatgcctatacaacagctgaagtggtt tattcttggactctcggaaagaacaaatccgtggaagtggcacaggatggttctcgcttg aaccagtatgaccttttgggccatgttgttgggacagagataatccggtctagtacagga gaatatgtcgtcatgacaacccacttccatctcaagcgaaaaattggctactttgtgatc cagacctacttgccatgtatcatgactgtcattctgtcacaagtgtcgttctggctcaac agagagtctgttcctgcccgtacagtctttggtgtcaccactgtgcttaccatgaccacc ttgagtatcagtgccagaaattccttacctaaagtggcatatgcgacggccatggactgg ttcatagccgtctgttatgcctttgtattttctgcactgattgaatttgccactgtcaac tatttcaccaagcggagttgggcttgggaaggcaagaaggtgccagaggccctggagatg aagaagaaaacaccagcagccccagcaaagaaaaccagcactaccttcaacatcgtgggg accacctatcccatcaacctggccaaggacactgaattttccaccatctccaagggcgct gctcccagtgcctcctcaaccccaacaatcattgcttcacccaaggccacctacgtgcag gacagcccgactgagaccaagacctacaacagtgtcagcaaggttgacaaaatttcccgc atcatctttcctgtgctctttgccatattcaatctggtctattgggccacatatgtcaac cgggagtcagctatcaagggcatgatccgcaaacagtag

Homo sapiens (human): 2557 Help Entry 2557              CDS       T01001                                  Symbol GABRA4 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit alpha4   KO K05175   gamma-aminobutyric acid receptor subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa04742   Taste transduction hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2557 (GABRA4)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2557 (GABRA4)    04723 Retrograde endocannabinoid signaling     2557 (GABRA4)   09157 Sensory system    04742 Taste transduction     2557 (GABRA4)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2557 (GABRA4)    05033 Nicotine addiction     2557 (GABRA4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2557 (GABRA4) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2557 (GABRA4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb OAD_gamma Motif Other DBs NCBI-GeneID:  2557 NCBI-ProteinID:  NP_000800 OMIM:  137141 HGNC:  4078 Ensembl:  ENSG00000109158 Vega:  OTTHUMG00000099431 Pharos:  P48169(Tclin) UniProt:  P48169 X5D7F5 LinkDB All DBs Position 4p12 AA seq 554 aa AA seqDB search MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPGQNQKEEKLCTENFTRILDSLLDGYD NRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLN NMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFP MDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSIT GEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMT TLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMEKAKRKTSKPPQ EVPAAPVQREKHPEAPLQNTNANLNMRKRTNALVHSESDVGNRTEVGNHSSKSSTVVQES SKGTPRSYLASSPNPFSRANAAETISAARALPSASPTSIRTGYMPRKASVGSASTRHVFG SRLQRIKTTVNTIGATGKLSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVV YLSKDTMEKSESLM NT seq 1665 nt NT seq  +upstreamnt  +downstreamnt atggtttctgccaagaaggtacccgcgatcgctctgtccgccggggtcagtttcgccctc ctgcgcttcctgtgcctggcggtttgtttaaacgaatccccaggacagaaccaaaaggag gagaaattgtgcacagaaaatttcacccgcatcctggacagtttgctcgatggttatgac aacaggctgcgtcctggatttgggggtcctgttacagaagtgaaaactgacatatatgtc accagctttggacctgtttctgatgttgaaatggaatacacaatggatgtgttcttcagg cagacatggattgacaaaagattaaaatatgacggccccattgaaattttgagattgaac aatatgatggtaacgaaagtgtggacccctgatactttcttcaggaatggaaagaaatct gtctcacataatatgacagctccaaataagctttttagaattatgagaaatggtactatt ttatacacaatgagactcaccataagtgcggagtgtcccatgagattggtggattttccc atggatggtcatgcatgccctttgaaattcgggagttatgcctatccaaagagtgagatg atctatacctggacaaaaggtcctgagaaatcagttgaagttccgaaggagtcttccagc ttagttcaatatgatttgattgggcaaaccgtatcaagtgaaaccatcaaatcaattacg ggtgaatatattgttatgacggtttacttccacctcagacggaagatgggttattttatg attcagacctatattccgtgcattatgacagtgattctttctcaagtttcattttggata aataaagaatcagttcccgctaggactgtatttggaataacaactgtcctcaccatgacc acactaagcatcagtgcacgacattctttgcccaaagtgtcctatgctaccgccatggac tggttcatagctgtctgctttgcttttgtattttcggcccttatcgagtttgctgctgtc aactatttcaccaatattcaaatggaaaaagccaaaaggaagacatcaaagccccctcag gaagttcccgctgctccagtgcagagagagaagcatcctgaagcccctctgcagaataca aatgccaatttgaacatgagaaaaagaacaaatgctttggttcactctgaatctgatgtt ggcaacagaactgaggtgggaaaccattcaagcaaatcttccacagttgttcaagaatct tctaaaggcacacctcggtcttacttagcttccagtccaaacccattcagccgtgcaaat gcagctgaaaccatatctgcagcaagagcacttccatctgcttctcctacttctatccga actggatatatgcctcgaaaggcttcagttggatctgcttctactcgtcacgtgtttgga tcaagactgcagaggataaagaccacagttaataccataggggctactgggaagttgtca gctactcctcctccatcggctccaccaccttctggatctggcacaagtaaaatagacaaa tatgcccgtattctctttccagtcacatttggggcatttaacatggtttattgggttgtt tatttatctaaggacactatggagaaatcagaaagtctaatgtaa

Homo sapiens (human): 2558 Help Entry 2558              CDS       T01001                                  Symbol GABRA5, DEE79, EIEE79 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit alpha5   KO K05175   gamma-aminobutyric acid receptor subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa04742   Taste transduction hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2558 (GABRA5)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2558 (GABRA5)    04723 Retrograde endocannabinoid signaling     2558 (GABRA5)   09157 Sensory system    04742 Taste transduction     2558 (GABRA5)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2558 (GABRA5)    05033 Nicotine addiction     2558 (GABRA5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2558 (GABRA5) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2558 (GABRA5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb CytochromB561_N Motif Other DBs NCBI-GeneID:  2558 NCBI-ProteinID:  NP_000801 OMIM:  137142 HGNC:  4079 Ensembl:  ENSG00000186297 Vega:  OTTHUMG00000171824 Pharos:  P31644(Tclin) UniProt:  P31644 LinkDB All DBs Structure PDB:  5O8F 6A96 Thumbnails Position 15q12 AA seq 462 aa AA seqDB search MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK NT seq 1389 nt NT seq  +upstreamnt  +downstreamnt atggacaatggaatgttctctggttttatcatgatcaaaaacctccttctcttttgtatt tccatgaacttatccagtcactttggcttttcacagatgccaaccagttcagtgaaagat gagaccaatgacaacatcacgatatttaccaggatcttggatgggctcttggatggctac gacaacagacttcggcccgggctgggagagcgcatcactcaggtgaggaccgacatctac gtcaccagcttcggcccggtgtccgacacggaaatggagtacaccatagacgtgtttttc cgacaaagctggaaagatgaaaggcttcggtttaaggggcccatgcagcgcctccctctc aacaacctccttgccagcaagatctggaccccagacacgttcttccacaacgggaagaag tccatcgctcacaacatgaccacgcccaacaagctgctgcggctggaggacgacggcacc ctgctctacaccatgcgcttgaccatctctgcagagtgccccatgcagcttgaggacttc ccgatggatgcgcacgcttgccctctgaaatttggcagctatgcgtaccctaattctgaa gtcgtttacgtctggaccaacggctccaccaagtcggtggtggtggcggaagatggctcc agactgaaccagtaccacctgatggggcagacggtgggcactgagaacatcagcaccagc acaggcgaatacacaatcatgacagctcacttccacctgaaaaggaagattggctacttt gtcatccagacctaccttccctgcataatgaccgtgatcttatcacaggtgtccttttgg ctgaaccgggaatcagtcccagccaggacagtttttggggtcaccacggtgctgaccatg acgaccctcagcatcagcgccaggaactctctgcccaaagtggcctacgccaccgccatg gactggttcatagccgtgtgctatgccttcgtcttctcggcgctgatagagtttgccacg gtcaattactttaccaagagaggctgggcctgggatggcaaaaaagccttggaagcagcc aagatcaagaaaaagcgtgaagtcatactaaataagtcaacaaacgcttttacaactggg aagatgtctcaccccccaaacattccgaaggaacagaccccagcagggacgtcgaataca acctcagtctcagtaaaaccctctgaagagaagacttctgaaagcaaaaagacttacaac agtatcagcaaaattgacaaaatgtcccgaatcgtattcccagtcttgttcggcactttc aacttagtttactgggcaacgtatttgaatagggagccggtgataaaaggagccgcctct ccaaaataa

Homo sapiens (human): 2559 Help Entry 2559              CDS       T01001                                  Symbol GABRA6 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit alpha6   KO K05175   gamma-aminobutyric acid receptor subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa04742   Taste transduction hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2559 (GABRA6)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2559 (GABRA6)    04723 Retrograde endocannabinoid signaling     2559 (GABRA6)   09157 Sensory system    04742 Taste transduction     2559 (GABRA6)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2559 (GABRA6)    05033 Nicotine addiction     2559 (GABRA6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2559 (GABRA6) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2559 (GABRA6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb DUF4396 Motif Other DBs NCBI-GeneID:  2559 NCBI-ProteinID:  NP_000802 OMIM:  137143 HGNC:  4080 Ensembl:  ENSG00000145863 Vega:  OTTHUMG00000130351 Pharos:  Q16445(Tclin) UniProt:  Q16445 LinkDB All DBs Position 5q34 AA seq 453 aa AA seqDB search MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE NT seq 1362 nt NT seq  +upstreamnt  +downstreamnt atggcgtcgtctctgccctggctgtgcattattctgtggctagaaaatgccctagggaaa ctcgaagttgaaggcaacttctactcagaaaacgtcagtcggatcctggacaacttgctt gaaggctatgacaatcggctgcggccgggatttggaggtgctgtcactgaagtcaaaaca gacatttatgtgaccagttttgggcccgtgtcagatgtggagatggagtatacgatggat gtttttttccgccagacctggactgatgagaggttgaagtttggggggccaactgagatt ctgagtctgaataatttgatggtcagtaaaatctggacgcctgacacctttttcagaaat ggtaaaaagtccattgctcacaacatgacaactcctaataaactcttcagaataatgcag aatggaaccattttatacaccatgaggcttaccatcaatgctgactgtcccatgaggctg gttaactttcctatggatgggcatgcttgtccactcaagtttgggagctatgcttatccc aaaagtgaaatcatatatacgtggaaaaaaggaccactttactcagtagaagtcccagaa gaatcttcaagccttctccagtatgatctgattggacaaacagtatctagtgagacaatt aaatctaacacaggtgaatacgttataatgacagtttacttccacttgcaaaggaagatg ggctacttcatgatacagatatacactccttgcattatgacagtcattctttcccaggtg tctttctggattaataaggagtccgtcccagcaagaactgtttttgggatcaccactgtt ttaactatgaccactttgagcatcagtgcccggcactctttgccaaaagtgtcatatgcc actgccatggattggttcatagctgtttgctttgcattcgtcttctctgcgcttatcgag ttcgcagctgtcaactactttaccaatcttcagacacagaaggccaaaaggaaggcacag tttgcagccccacccacagtgacaatatcaaaagctactgaacctttggaagctgagatt gttttgcatcctgactccaaatatcatctgaagaaaaggatcacttctctgtctttgcca atagtttcatcttccgaggccaataaagtgctcacgagagcgcccatcttacaatcaaca cctgtcacacccccaccactctcgccagcctttggaggcaccagtaaaatagaccagtat tctcgaattctcttcccagttgcatttgcaggattcaaccttgtgtactgggtagtttat ctttccaaagatacaatggaagtcagtagcagtgttgaatag

Homo sapiens (human): 2560 Help Entry 2560              CDS       T01001                                  Symbol GABRB1, DEE45, EIEE45 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit beta1   KO K05181   gamma-aminobutyric acid receptor subunit beta Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04726   Serotonergic synapse hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2560 (GABRB1)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2560 (GABRB1)    04726 Serotonergic synapse     2560 (GABRB1)    04723 Retrograde endocannabinoid signaling     2560 (GABRB1)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2560 (GABRB1)    05033 Nicotine addiction     2560 (GABRB1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2560 (GABRB1) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2560 (GABRB1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb OAD_gamma Motif Other DBs NCBI-GeneID:  2560 NCBI-ProteinID:  NP_000803 OMIM:  137190 HGNC:  4081 Ensembl:  ENSG00000163288 Vega:  OTTHUMG00000044269 Pharos:  P18505(Tclin) UniProt:  P18505 X5DNL6 LinkDB All DBs Position 4p12 AA seq 474 aa AA seqDB search MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQ VDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDR HGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH NT seq 1425 nt NT seq  +upstreamnt  +downstreamnt atgtggacagtacaaaatcgagagagtctggggcttctctctttccctgtgatgattacc atggtctgttgtgcacacagcaccaatgaacccagcaacatgtcatacgtgaaagagaca gtggacagattgctcaaaggatatgacattcgcttgcggccggacttcggagggcccccc gtcgacgttgggatgcggatcgatgtcgccagcatagacatggtctccgaagtgaatatg gattatacactcaccatgtatttccagcagtcttggaaagacaaaaggctttcttattct ggaatcccactgaacctcaccctagacaatagggtagctgaccaactctgggtaccagac acctactttctgaatgacaagaaatcatttgtgcatggggtcacagtgaaaaatcgaatg attcgactgcatcctgatggaacagttctctatggactccgaatcacaaccacagctgca tgtatgatggatcttcgaagatatccattggatgagcagaactgcaccctggagatcgaa agttatggctataccactgatgacattgaattttactggaatggaggagaaggggcagtc actggtgttaataaaatcgaacttcctcaattttcaattgttgactacaagatggtgtct aagaaggtggagttcacaacaggagcgtatccacgactgtcactaagttttcgtctaaag agaaacattggttacttcattttgcaaacctacatgccttctacactgattacaattctg tcctgggtgtctttttggatcaactatgatgcatctgcagccagagtcgcactaggaatc acgacagtgcttacaatgacaaccatcagcacccacctcagggagaccctgccaaagatc ccttatgtcaaagcgattgatatttatctgatgggttgctttgtgtttgtgttcctggct ctgctggagtatgcctttgtaaattacatcttctttgggaaaggccctcagaaaaaggga gctagcaaacaagaccagagtgccaatgagaagaataaactggagatgaataaagtccag gtcgacgcccacggtaacattctcctcagcaccctggaaatccggaatgagacgagtggc tcggaagtgctcacgagcgtgagcgaccccaaggccaccatgtactcctatgacagcgcc agcatccagtaccgcaagcccctgagcagccgcgaggcctacgggcgcgccctggaccgg cacggggtacccagcaaggggcgcatccgcaggcgtgcctcccagctcaaagtcaagatc cccgacttgactgatgtgaattccatagacaagtggtcccgaatgtttttccccatcacc ttttctctttttaatgtcgtctattggctttactatgtacactga

Homo sapiens (human): 2561 Help Entry 2561              CDS       T01001                                  Symbol GABRB2, DEE92, ICEE2 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit beta2   KO K05181   gamma-aminobutyric acid receptor subunit beta Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04726   Serotonergic synapse hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy H02150   Infantile or early childhood epileptic encephalopathy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2561 (GABRB2)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2561 (GABRB2)    04726 Serotonergic synapse     2561 (GABRB2)    04723 Retrograde endocannabinoid signaling     2561 (GABRB2)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2561 (GABRB2)    05033 Nicotine addiction     2561 (GABRB2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2561 (GABRB2) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2561 (GABRB2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2561 NCBI-ProteinID:  NP_068711 OMIM:  600232 HGNC:  4082 Ensembl:  ENSG00000145864 Vega:  OTTHUMG00000130349 Pharos:  P47870(Tclin) UniProt:  P47870 LinkDB All DBs Structure PDB:  6D6T 6D6U Thumbnails Position 5q34 AA seq 512 aa AA seqDB search MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN NT seq 1539 nt NT seq  +upstreamnt  +downstreamnt atgtggagagtgcggaaaaggggctactttgggatttggtccttccccttaataatcgcc gctgtctgtgcgcagagtgtcaatgaccctagtaatatgtcgctggttaaagagacggtg gatagactcctgaaaggctatgacattcgtctgagaccagattttggaggtccccccgtg gctgtggggatgaacattgacattgccagcatcgatatggtttctgaagtcaatatggat tataccttgacaatgtactttcaacaagcctggagagataagaggctgtcctataatgta atacctttaaacttgactctggacaacagagtggcagaccagctctgggtgcctgatacc tatttcctgaacgataagaagtcatttgtgcacggagtgactgttaagaaccgcatgatt cgcctgcatcctgatggcaccgtcctttatggactcagaatcacaaccacagctgcctgc atgatggacctaaggaggtacccactggatgaacaaaactgcaccttggaaattgagagc tatggatacacaactgatgacattgagttttactggcgtggcgatgataatgcagtaaca ggagtaacgaaaattgaacttccacagttctctattgtagattacaaacttatcaccaag aaggttgttttttccacaggttcctatcccaggttatccctcagctttaagcttaagaga aacattggctactttatcctgcaaacatacatgccttccatcctgattaccatcctctcc tgggtctccttctggattaattacgatgcttcagctgcaagggtggcattaggaatcaca actgtcctcacaatgaccacaatcaacacccacctccgggaaactctccctaaaatcccc tatgtgaaggccattgacatgtacctgatggggtgctttgtcttcgttttcatggccctt ctggaatatgccctagtcaactacatcttctttgggagggggccccaacgccaaaagaaa gcagctgagaaggctgccagtgccaacaatgagaagatgcgcctggatgtcaacaagatt ttttataaagatattaaacaaaatgggacccaatatcgatccttgtgggaccctactgga aacctctccccaactagacggactaccaattacgatttctctctgtatacgatggacccc catgagaacatcttactgagcactctcgagataaaaaatgaaatggccacatctgaggct gtgatgggacttggagaccccagaagcacaatgctagcctatgatgcctccagcatccag tatcggaaagctgggttgcccaggcatagttttggccgaaatgctctggaacgacatgtg gcgcaaaagaaaagtcgcctgaggagacgcgcctcccaactgaaaatcaccatccctgac ttgactgatgtgaatgccatagatcggtggtcccgcatattcttcccagtggttttttcc ttcttcaacatcgtctattggctttattatgtgaactaa

Homo sapiens (human): 2562 Help Entry 2562              CDS       T01001                                  Symbol GABRB3, DEE43, ECA5, EIEE43 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit beta3   KO K05181   gamma-aminobutyric acid receptor subunit beta Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04726   Serotonergic synapse hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy H02215   Childhood absence epilepsy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2562 (GABRB3)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2562 (GABRB3)    04726 Serotonergic synapse     2562 (GABRB3)    04723 Retrograde endocannabinoid signaling     2562 (GABRB3)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2562 (GABRB3)    05033 Nicotine addiction     2562 (GABRB3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2562 (GABRB3) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2562 (GABRB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb OAD_gamma Motif Other DBs NCBI-GeneID:  2562 NCBI-ProteinID:  NP_000805 OMIM:  137192 HGNC:  4083 Ensembl:  ENSG00000166206 Vega:  OTTHUMG00000129231 Pharos:  P28472(Tclin) UniProt:  P28472 LinkDB All DBs Structure PDB:  4COF 6HUJ 6HUG 6I53 6HUO 6A96 6HUP 6HUK Thumbnails Position 15q12 AA seq 473 aa AA seqDB search MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN NT seq 1422 nt NT seq  +upstreamnt  +downstreamnt atgtggggccttgcgggaggaaggcttttcggcatcttctcggccccggtgctggtggct gtggtgtgctgcgcccagagtgtgaacgatcccgggaacatgtcctttgtgaaggagacg gtggacaagctgttgaaaggctacgacattcgcctaagacccgacttcgggggtcccccg gtctgcgtggggatgaacatcgacatcgccagcatcgacatggtttccgaagtcaacatg gattataccttaaccatgtattttcaacaatattggagagataaaaggctcgcctattct gggatccctctcaacctcacgcttgacaatcgagtggctgaccagctatgggtgcccgac acatatttcttaaatgacaaaaagtcatttgtgcatggagtgacagtgaaaaaccgcatg atccgtcttcaccctgatgggacagtgctgtatgggctcagaatcaccacgacagcagca tgcatgatggacctcaggagataccccctggacgagcagaactgcactctggaaattgaa agctatggctacaccacggatgacattgagttttactggcgaggcggggacaaggctgtt accggagtggaaaggattgagctcccgcagttctccatcgtggagcaccgtctggtctcg aggaatgttgtcttcgccacaggtgcctatcctcgactgtcactgagctttcggttgaag aggaacattggatacttcattcttcagacttatatgccctctatactgataacgattctg tcgtgggtgtccttctggatcaattatgatgcatctgctgctagagttgccctcgggatc acaactgtgctgacaatgacaaccatcaacacccaccttcgggagaccttgcccaaaatc ccctatgtcaaagccattgacatgtaccttatgggctgcttcgtctttgtgttcctggcc cttctggagtatgcctttgtcaactacattttctttggaagaggccctcaaaggcagaag aagcttgcagaaaagacagccaaggcaaagaatgaccgttcaaagagcgaaagcaaccgg gtggatgctcatggaaatattctgttgacatcgctggaagttcacaatgaaatgaatgag gtctcaggcggcattggcgataccaggaattcagcaatatcctttgacaactcaggaatc cagtacaggaaacagagcatgcctcgagaagggcatgggcgattcctgggggacagaagc ctcccgcacaagaagacccatctacggaggaggtcttcacagctcaaaattaaaatacct gatctaaccgatgtgaatgccatagacagatggtccaggatcgtgtttccattcactttt tctcttttcaacttagtttactggctgtactatgttaactga

Homo sapiens (human): 2563 Help Entry 2563              CDS       T01001                                  Symbol GABRD, EIG10, EJM7, GEFSP5 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit delta   KO K05184   gamma-aminobutyric acid receptor subunit delta Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00783   Febrile seizures H00808   Idiopathic generalized epilepsies H02217   Juvenile myoclonic epilepsy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2563 (GABRD)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2563 (GABRD)    04723 Retrograde endocannabinoid signaling     2563 (GABRD)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2563 (GABRD)    05033 Nicotine addiction     2563 (GABRD)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2563 (GABRD) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2563 (GABRD) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2563 NCBI-ProteinID:  NP_000806 OMIM:  137163 HGNC:  4084 Ensembl:  ENSG00000187730 Vega:  OTTHUMG00000041064 Pharos:  O14764(Tclin) UniProt:  O14764 A8K496 LinkDB All DBs Position 1p36.33 AA seq 452 aa AA seqDB search MDAPARLLAPLLLLCAQQLRGTRAMNDIGDYVGSNLEISWLPNLDGLIAGYARNFRPGIG GPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNETLGLDSRFVDKLW LPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECML DLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQFPRLSLH FHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSS LPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRPRAEMDVRNAI VLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSGGQGGIRARLR PIDADTIDIYARAVFPAAFAAVNVIYWAAYAM NT seq 1359 nt NT seq  +upstreamnt  +downstreamnt atggacgcgcccgcccggctgctggccccgctcctgctcctctgcgcgcagcagctccgc ggcaccagagcgatgaatgacatcggcgactacgtgggctccaacctggagatctcctgg ctccccaacctggacgggctgatagccggctacgcccgcaacttccggcctggcatcgga ggcccccccgtgaatgtggcccttgccctggaggtggccagcatcgaccacatctcagag gccaacatggagtacaccatgacggtgttcctgcaccagagctggcgggacagcaggctc tcctacaaccacaccaacgagaccctgggtctggacagccgcttcgtggacaagctgtgg ctgcccgacaccttcatcgtgaacgccaagtcggcctggttccacgacgtgacggtggag aacaagctcatccggctgcagcccgacggcgtgatcctgtacagcatccgaatcacctcc actgtggcctgcgacatggacctggccaaataccccatggacgagcaggagtgcatgctg gacctggagagctacggttactcatcggaggacatcgtctactactggtcggagagccag gagcacatccacgggctggacaagctgcagctggcgcagttcaccatcaccagctaccgc ttcaccacggagctgatgaacttcaagtccgctggccagttcccacggctcagcctgcac ttccacctgcggaggaaccgcggcgtgtacatcatccaatcctacatgccctccgtcctg ctggtcgccatgtcctgggtctccttctggatcagccaggcggcggtgcccgccagggtg tctctaggcatcaccacggtgctgacgatgaccacgctcatggtcagtgcccgctcctcc ctgccacgggcatcagccatcaaggcactggacgtctacttctggatctgctatgtcttc gtgtttgccgccctggtggagtacgcctttgctcatttcaacgccgactacaggaagaag cagaaggccaaggtcaaggtctccaggccgagggcagagatggacgtgaggaacgccatt gtcctcttctccctctctgctgccggcgtcacgcaggagctggccatctcccgccggcag cgccgcgtcccggggaacctgatgggctcctacaggtcggtgggggtggagacaggggag acgaagaaggagggggcagcccgctcaggaggccaggggggcatccgtgcccggctcagg cccatcgacgcagacaccattgacatttacgcccgcgctgtgttccctgcggcgtttgcg gccgtcaatgtcatctactgggcggcatacgccatgtga

Homo sapiens (human): 2564 Help Entry 2564              CDS       T01001                                  Symbol GABRE Name (RefSeq) gamma-aminobutyric acid type A receptor subunit epsilon   KO K05185   gamma-aminobutyric acid receptor subunit epsilon Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2564 (GABRE)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2564 (GABRE)    04723 Retrograde endocannabinoid signaling     2564 (GABRE)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2564 (GABRE)    05033 Nicotine addiction     2564 (GABRE)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2564 (GABRE) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2564 (GABRE) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2564 NCBI-ProteinID:  NP_004952 OMIM:  300093 HGNC:  4085 Ensembl:  ENSG00000102287 Vega:  OTTHUMG00000024176 Pharos:  P78334(Tclin) UniProt:  P78334 LinkDB All DBs Position Xq28 AA seq 506 aa AA seqDB search MLSKVLPVLLGILLILQSRVEGPQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETE TGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDI IFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKD GKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSW KLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFW IKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAV LNFLIYNQTKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEER PSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRL DNYSRVVFPVTFFFFNVLYWLVCLNL NT seq 1521 nt NT seq  +upstreamnt  +downstreamnt atgttgtccaaagttcttccagtcctcctaggcatcttattgatcctccagtcgagggtc gagggacctcagactgaatcaaagaatgaagcctcttcccgtgatgttgtctatggcccc cagccccagcctctggaaaatcagctcctctctgaggaaacaaagtcaactgagactgag actgggagcagagttggcaaactgccagaagcctctcgcatcctgaacactatcctgagt aattatgaccacaaactgcgccctggcattggagagaagcccactgtggtcactgttgag atctccgtcaacagccttggtcctctctctatcctagacatggaatacaccattgacatc atcttctcccagacctggtacgacgaacgcctctgttacaacgacacctttgagtctctt gttctgaatggcaatgtggtgagccagctatggatcccggacaccttttttaggaattct aagaggacccacgagcatgagatcaccatgcccaaccagatggtccgcatctacaaggat ggcaaggtgttgtacacaattaggatgaccattgatgccggatgctcactccacatgctc agatttccaatggattctcactcttgccctctatctttctctagcttttcctatcctgag aatgagatgatctacaagtgggaaaatttcaagcttgaaatcaatgagaagaactcctgg aagctcttccagtttgattttacaggagtgagcaacaaaactgaaataatcacaacccca gttggtgacttcatggtcatgacgattttcttcaatgtgagcaggcggtttggctatgtt gcctttcaaaactatgtcccttcttccgtgaccacgatgctctcctgggtttccttttgg atcaagacagagtctgctccagcccggacctctctagggatcacctctgttctgaccatg accacgttgggcaccttttctcgtaagaatttcccgcgtgtctcctatatcacagccttg gatttctatatcgccatctgcttcgtcttctgcttctgcgctctgttggagtttgctgtg ctcaacttcctgatctacaaccagacaaaagcccatgcttctcctaaactccgccatcct cgtatcaatagccgtgcccatgcccgtacccgtgcacgttcccgagcctgtgcccgccaa catcaggaagcttttgtgtgccagattgtcaccactgagggaagtgatggagaggagcgc ccgtcttgctcagcccagcagccccctagcccaggtagccctgagggtccccgcagcctc tgctccaagctggcctgctgtgagtggtgcaagcgttttaagaagtacttctgcatggtc cccgattgtgagggcagtacctggcagcagggccgcctctgcatccatgtctaccgcctg gataactactcgagagttgttttcccagtgactttcttcttcttcaatgtgctctactgg cttgtttgccttaacttgtag

Homo sapiens (human): 2565 Help Entry 2565              CDS       T01001                                  Symbol GABRG1 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit gamma1   KO K05186   gamma-aminobutyric acid receptor subunit gamma Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2565 (GABRG1)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2565 (GABRG1)    04723 Retrograde endocannabinoid signaling     2565 (GABRG1)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2565 (GABRG1)    05033 Nicotine addiction     2565 (GABRG1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2565 (GABRG1) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2565 (GABRG1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2565 NCBI-ProteinID:  NP_775807 OMIM:  137166 HGNC:  4086 Ensembl:  ENSG00000163285 Vega:  OTTHUMG00000128609 Pharos:  Q8N1C3(Tclin) UniProt:  Q8N1C3 LinkDB All DBs Position 4p12 AA seq 465 aa AA seqDB search MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIH EGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWF DSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTL RLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF VGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVP ARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFE DCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgggtcctttgaaagcttttctcttctccccttttcttctgcggagtcaaagtagaggg gtgaggttggtcttcttgttactgaccctgcatttgggaaactgtgttgataaggcagat gatgaagatgatgaggatttaacggtgaacaaaacctgggtcttggccccaaaaattcat gaaggagatatcacacaaattctgaattcattgcttcaaggctatgacaataaacttcgt ccagatataggagtgaggcccacagtaattgaaactgatgtttatgtaaacagcattgga ccagttgatccaattaatatggaatatacaatagatataatttttgcccaaacctggttt gacagtcgtttaaaattcaatagtaccatgaaagtgcttatgcttaacagtaatatggtt ggaaaaatttggattcctgacactttcttcagaaactcaagaaaatctgatgctcactgg ataacaactcctaatcgtctgcttcgaatttggaatgatggacgagttctgtatactcta agattgacaattaatgcagaatgttatcttcagcttcataactttcccatggatgaacat tcctgtccactggaattttcaagctatggataccctaaaaatgaaattgagtataagtgg aaaaagccctccgtagaagtggctgatcctaaatactggagattatatcagtttgcattt gtagggttacggaactcaactgaaatcactcacacgatctctggggattatgttatcatg acaattttttttgacctgagcagaagaatgggatatttcactattcagacctacattcca tgcattctgacagttgttctttcttgggtgtctttttggatcaataaagatgcagtgcct gcaagaacatcgttgggtatcactacagttctgactatgacaaccctgagtacaattgcc aggaagtctttacctaaggtttcttatgtgactgcgatggatctctttgtttctgtttgt ttcatttttgtttttgcagccttgatggaatatggaaccttgcattattttaccagcaac caaaaaggaaagactgctactaaagacagaaagctaaaaaataaagcctcgatgactcct ggtctccatcctggatccactctgattccaatgaataatatttctgtgccgcaagaagat gattatgggtatcagtgtttggagggcaaagattgtgccagcttcttctgttgctttgaa gactgcagaacaggatcttggagggaaggaaggatacacatacgcattgccaaaattgac tcttattctagaatatttttcccaaccgcttttgccctgttcaacttggtttattgggtt ggctatctttacttataa

Homo sapiens (human): 2566 Help Entry 2566              CDS       T01001                                  Symbol GABRG2, CAE2, DEE74, ECA2, EIEE74, FEB8, GEFSP3 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit gamma2   KO K05186   gamma-aminobutyric acid receptor subunit gamma Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Disease H00606   Early infantile epileptic encephalopathy H00783   Febrile seizures H02215   Childhood absence epilepsy Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2566 (GABRG2)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2566 (GABRG2)    04723 Retrograde endocannabinoid signaling     2566 (GABRG2)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2566 (GABRG2)    05033 Nicotine addiction     2566 (GABRG2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2566 (GABRG2) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2566 (GABRG2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2566 NCBI-ProteinID:  NP_000807 OMIM:  137164 HGNC:  4087 Ensembl:  ENSG00000113327 Vega:  OTTHUMG00000130350 Pharos:  P18507(Tclin) UniProt:  P18507 LinkDB All DBs Structure PDB:  6HUJ 6HUG 6I53 6HUO 6HUP 6HUK 6D6T 6D6U Thumbnails Position 5q34 AA seq 467 aa AA seqDB search MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV SNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCC FEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt atgagttcgccaaatatatggagcacaggaagctcagtctactcgactcctgtattttca cagaaaatgacggtgtggattctgctcctgctgtcgctctaccctggcttcactagccag aaatctgatgatgactatgaagattatgcttctaacaaaacatgggtcttgactccaaaa gttcctgagggtgatgtcactgtcatcttaaacaacctgctggaaggatatgacaataaa cttcggcctgatataggagtgaagccaacgttaattcacacagacatgtatgtgaatagc attggtccagtgaacgctatcaatatggaatacactattgatatattttttgcgcaaacg tggtatgacagacgtttgaaatttaacagcaccattaaagtcctccgattgaacagcaac atggtggggaaaatctggattccagacactttcttcagaaattccaaaaaagctgatgca cactggatcaccacccccaacaggatgctgagaatttggaatgatggtcgagtgctctac accctaaggttgacaattgatgctgagtgccaattacaattgcacaactttccaatggat gaacactcctgccccttggagttctccagttatggctatccacgtgaagaaattgtttat caatggaagcgaagttctgttgaagtgggcgacacaagatcctggaggctttatcaattc tcatttgttggtctaagaaataccaccgaagtagtgaagacaacttccggagattatgtg gtcatgtctgtctactttgatctgagcagaagaatgggatactttaccatccagacctat atcccctgcacactcattgtcgtcctatcctgggtgtctttctggatcaataaggatgct gttccagccagaacatctttaggtatcaccactgtcctgacaatgaccaccctcagcacc attgcccggaaatcgctccccaaggtctcctatgtcacagcgatggatctctttgtatct gtttgtttcatctttgtcttctctgctctggtggagtatggcaccttgcattattttgtc agcaaccggaaaccaagcaaggacaaagataaaaagaagaaaaaccctgcccctaccatt gatatccgcccaagatcagcaaccattcaaatgaataatgctacacaccttcaagagaga gatgaagagtacggctatgagtgtctggacggcaaggactgtgccagttttttctgctgt tttgaagattgtcgaacaggagcttggagacatgggaggatacatatccgcattgccaaa atggactcctatgctcggatcttcttccccactgccttctgcctgtttaatctggtctat tgggtctcctacctctacctgtga

Homo sapiens (human): 2567 Help Entry 2567              CDS       T01001                                  Symbol GABRG3 Name (RefSeq) gamma-aminobutyric acid type A receptor subunit gamma3   KO K05186   gamma-aminobutyric acid receptor subunit gamma Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2567 (GABRG3)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2567 (GABRG3)    04723 Retrograde endocannabinoid signaling     2567 (GABRG3)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2567 (GABRG3)    05033 Nicotine addiction     2567 (GABRG3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2567 (GABRG3) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2567 (GABRG3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2567 NCBI-ProteinID:  NP_150092 OMIM:  600233 HGNC:  4088 Ensembl:  ENSG00000182256 Vega:  OTTHUMG00000044462 Pharos:  Q99928(Tclin) UniProt:  Q99928 LinkDB All DBs Position 15q12 AA seq 467 aa AA seqDB search MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDK KLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNS NMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPM DEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDY VVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLS TIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDS SRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCC YEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt atggccccgaagctgctgctcctcctctgcctgttctcgggcttgcacgcgcggtccaga aaggtggaagaggatgaatatgaagattcatcatcaaaccaaaagtgggtcttggctcca aaatcccaagacaccgacgtgactcttattctcaacaagttgctaagagaatatgataaa aagctgaggccagatattggaataaaaccgaccgtaattgacgttgacatttatgttaac agcattggtcctgtgtcatcaataaacatggaataccaaattgacatattttttgctcag acctggacagatagtcgccttcgattcaacagcacaatgaaaattcttactctgaacagc aacatggtggggttaatctggatcccagacaccatcttccgcaattctaaaaccgcagag gctcactggatcaccacacccaatcagctcctccggatttggaatgacgggaaaatcctt tacactttgaggctcaccatcaatgctgagtgccagctgcagctgcacaacttccccatg gacgaacactcctgcccgctgattttctccagctatggctatcccaaagaagaaatgatt tatagatggagaaaaaattcagtggaggcagctgaccagaaatcatggcggctttatcag tttgacttcatgggcctcagaaacaccacagaaatcgtgacaacgtctgcaggtgattat gttgtcatgactatatattttgaattgagtagaagaatgggatacttcaccattcagaca tacattccctgtatactgactgtggttttatcctgggtgtcattttggatcaaaaaagat gctacgccagcaagaacagcattaggcatcaccacggtgctgaccatgaccaccctgagc accatcgccaggaagtccttgccacgcgtgtcctacgtgaccgccatggacctttttgtg accgtgtgcttcctgtttgtcttcgccgcgctgatggagtatgccaccctcaactactat tccagctgtagaaaaccaaccaccacgaagaagacaacatcgttactacatccagattcc tcaagatggattcctgagcgaataagcctacaagccccttccaactattccctcctggac atgaggccaccaccaactgcgatgatcactttaaacaattccgtttactggcaggaattt gaagatacctgtgtctatgagtgtctggatggcaaagactgtcagagcttcttctgctgc tatgaagaatgtaaatcaggatcctggaggaaagggcgtattcacatagacatcttggag ctggactcgtactcccgggtctttttccccacgtccttcctgctctttaacctggtctac tgggttggatacctgtatctctaa

Homo sapiens (human): 2568 Help Entry 2568              CDS       T01001                                  Symbol GABRP Name (RefSeq) gamma-aminobutyric acid type A receptor subunit pi   KO K05189   gamma-aminobutyric acid receptor subunit pi Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2568 (GABRP)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     2568 (GABRP)    04723 Retrograde endocannabinoid signaling     2568 (GABRP)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2568 (GABRP)    05033 Nicotine addiction     2568 (GABRP)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     2568 (GABRP) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    2568 (GABRP) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  2568 NCBI-ProteinID:  NP_055026 OMIM:  602729 HGNC:  4089 Ensembl:  ENSG00000094755 Vega:  OTTHUMG00000130443 Pharos:  O00591(Tclin) UniProt:  O00591 LinkDB All DBs Position 5q35.1 AA seq 440 aa AA seqDB search MNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGEP VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLVEFLWVPDT YIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLES WGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQFELRR NVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTN CFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDRGTTKEVEEVSITNIINSSIS SFKRKISFASIEISSDNVDYSDLTMKTSDKFKFVFREKMGRIVDYFTIQNPSNVDHYSKL LFPLIFMLANVFYWAYYMYF NT seq 1323 nt NT seq  +upstreamnt  +downstreamnt atgaactacagcctccacttggccttcgtgtgtctgagtctcttcactgagaggatgtgc atccaggggagtcagttcaacgtcgaggtcggcagaagtgacaagctttccctgcctggc tttgagaacctcacagcaggatataacaaatttctcaggcccaattttggtggagaaccc gtacagatagcgctgactctggacattgcaagtatctctagcatttcagagagtaacatg gactacacagccaccatatacctccgacagcgctggatggaccagcggctggtgtttgaa ggcaacaagagcttcactctggatgcccgcctcgtggagttcctctgggtgccagatact tacattgtggagtccaagaagtccttcctccatgaagtcactgtgggaaacaggctcatc cgcctcttctccaatggcacggtcctgtatgccctcagaatcacgacaactgttgcatgt aacatggatctgtctaaataccccatggacacacagacatgcaagttgcagctggaaagc tggggctatgatggaaatgatgtggagttcacctggctgagagggaacgactctgtgcgt ggactggaacacctgcggcttgctcagtacaccatagagcggtatttcaccttagtcacc agatcgcagcaggagacaggaaattacactagattggtcttacagtttgagcttcggagg aatgttctgtatttcattttggaaacctacgttccttccactttcctggtggtgttgtcc tgggtttcattttggatctctctcgattcagtccctgcaagaacctgcattggagtgacg accgtgttatcaatgaccacactgatgatcgggtcccgcacttctcttcccaacaccaac tgcttcatcaaggccatcgatgtgtacctggggatctgctttagctttgtgtttggggcc ttgctagaatatgcagttgctcactacagttccttacagcagatggcagccaaagatagg gggacaacaaaggaagtagaagaagtcagtattactaatatcatcaacagctccatctcc agctttaaacggaagatcagctttgccagcattgaaatttccagcgacaacgttgactac agtgacttgacaatgaaaaccagcgacaagttcaagtttgtcttccgagaaaagatgggc aggattgttgattatttcacaattcaaaaccccagtaatgttgatcactattccaaacta ctgtttcctttgatttttatgctagccaatgtattttactgggcatactacatgtatttt tga

Homo sapiens (human): 55879 Help Entry 55879             CDS       T01001                                  Symbol GABRQ, THETA Name (RefSeq) gamma-aminobutyric acid type A receptor subunit theta   KO K05192   gamma-aminobutyric acid receptor subunit theta Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04723   Retrograde endocannabinoid signaling hsa04727   GABAergic synapse hsa05032   Morphine addiction hsa05033   Nicotine addiction Drug target Abecarnil:  D02594 Adinazolam (DG00911):  D02770 D02771 Adipiplon:  D08840 Alpidem:  D02833 Alprazolam:  D00225<JP/US> Aminobutyric acid:  D00058<JP> Amobarbital (DG00916):  D00555<JP> D02252 Aprobarbital:  D00698 Barbexaclone:  D07298 Barbital:  D01740 Bretazenil:  D03155 Brexanolone:  D11149<US> Bromazepam:  D01245<JP> Brotizolam:  D01744<JP> Butabarbital (DG01308):  D00699 D03180 Butobarbital:  D02618 Cenobamate:  D11150<US> Chlordiazepoxide (DG00908):  D00267<JP> D00693<US> Cinolazepam:  D07328 Clobazam:  D01253<JP/US> Clonazepam:  D00280<JP/US> Clotiazepam:  D01328<JP> Cloxazolam:  D01268<JP> Darigabat:  D12146 Delorazepam:  D07784 Dextofisopam:  D03737 Diazepam:  D00293<JP/US> Estazolam:  D00311<JP/US> Eszopiclone:  D02624<JP/US> Ethyl loflazepate:  D01293<JP> Etizolam:  D01514<JP> Fludiazepam:  D01354<JP> Flumazenil:  D00697<JP/US> Flunitrazepam:  D01230<JP> Flurazepam (DG00919):  D00329 D00695<US> D01408<JP> Flutazolam:  D01286<JP> Flutoprazepam:  D01279<JP> Gaboxadol:  D04282 Ganaxolone:  D04300 Glutethimide:  D00532 Halazepam:  D00338 Haloxazolam:  D01758<JP> Hexobarbital:  D01071 Indiplon:  D02640 Iomazenil:  D02283<JP> Ketazolam:  D04650 Levotofisopam:  D04721 Loprazolam (DG00921):  D07326 D08145 Lorazepam:  D00365<JP/US> Lormetazepam:  D01657<JP> Medazepam (DG00909):  D01292<JP> D04882 Meprobamate:  D00376<US> Metharbital:  D01382 Methylphenobarbital:  D00700 Mexazolam:  D01316<JP> Midazolam (DG00920):  D00550<JP/US> D00696<US> D05028 Nimetazepam:  D01593 Nitrazepam:  D00531<JP> Nordazepam:  D08283 Ocinaplon:  D02617 Oxazepam:  D00464<US> Oxazolam:  D01278<JP> Pagoclone:  D02616 Panadiplon:  D05346 Pazinaclone:  D05378 Pentobarbital (DG00915):  D00499 D00500<US> D02253<JP> Phenobarbital (DG00845):  D00506<JP> D00701<JP> D08356 Potassium clorazepate (DG01218):  D00694<JP/US> D03562 Prazepam:  D00470 Propofol (DG00797):  D00549<JP/US> D04257 Quazepam:  D00457<JP/US> Remimazolam (DG03105):  D10194<JP/US> D11788 Rilmazafone (DG01307):  D01564<JP> D08481 Sarmazenil:  D08507 Secobarbital (DG00917):  D00430 D01310<JP> Suritozole:  D05980 Talbutal:  D06887 Temazepam:  D00370<US> Thiamylal (DG01377):  D00713<JP> D06106 Thiopental (DG00790):  D00714<JP> Tofisopam:  D01254<JP> Topiramate:  D00537<JP/US> Triazolam:  D00387<JP/US> Zolpidem (DG00922):  D00706<JP/US> D08690 Zopiclone:  D01372<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     55879 (GABRQ)  09150 Organismal Systems   09156 Nervous system    04727 GABAergic synapse     55879 (GABRQ)    04723 Retrograde endocannabinoid signaling     55879 (GABRQ)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     55879 (GABRQ)    05033 Nicotine addiction     55879 (GABRQ)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     55879 (GABRQ) Ion channels [BR:hsa04040]  Ligand-gated channels   GABA-A    55879 (GABRQ) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Neur_chan_LBD Neur_chan_memb Motif Other DBs NCBI-GeneID:  55879 NCBI-ProteinID:  NP_061028 OMIM:  300349 HGNC:  14454 Ensembl:  ENSG00000268089 Vega:  OTTHUMG00000022649 Pharos:  Q9UN88(Tclin) UniProt:  Q9UN88 LinkDB All DBs Position Xq28 AA seq 632 aa AA seqDB search MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQ KILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLA YYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTT AACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTI TSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTI GLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRR QPRRHRRPRRVIARYRYQQVVVGNVQDGLINVEDGVSSLPITPAQAPLASPESLGSLTST SEQAQLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPT EIRNRVEAHGHGVTHDHEDSNESLSSDERHGHGPSGKPMLHHGEKGVQEAGWDLDDNNDK SDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFN PDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY NT seq 1899 nt NT seq  +upstreamnt  +downstreamnt atgggcatccgaggcatgctgcgagccgcagtgatcctgctgctcatcaggacctggctc gcggagggcaactaccccagtcccatcccgaaattccacttcgagttctcctctgctgtg cccgaagtcgtcctgaacctcttcaactgcaaaaattgtgcaaatgaagctgtggttcaa aagattttggacagggtgctgtcaagatacgatgtccgcctgagaccgaattttggaggt gcccctgtgcctgtgagaatatctatttatgtcacgagcattgaacagatctcagaaatg aatatggactacacgatcacgatgttttttcatcagacttggaaagattcacgcttagca tactatgagaccaccctgaacttgaccctggactatcggatgcatgagaagttgtgggtc cctgactgctactttctgaacagcaaggatgctttcgtgcatgatgtgactgtggagaat cgcgtgtttcagcttcacccagatggaacggtgcggtacggcatccgactcaccactaca gcagcttgttccctggatctgcataaattccctatggacaagcaggcctgcaacctggtg gtagagagctatggttacacggttgaagacatcatattattctgggatgacaatgggaac gccatccacatgactgaggagctgcatatccctcagttcactttcctgggaaggacgatt actagcaaggaggtgtatttctacacaggttcctacatacgcctgatactgaagttccag gttcagagggaagttaacagctaccttgtgcaagtctactggcctactgtcctcaccact attacctcttggatatcgttttggatgaactatgattcctctgcagccagggtgacaatt ggcttaacttcaatgctcatcctgaccaccatcgactcacatctgcgggataagctcccc aacatttcctgtatcaaggccattgatatctatatcctcgtgtgcttgttctttgtgttc ctgtccttgctggagtatgtctacatcaactatcttttctacagtcgaggacctcggcgc cagcctaggcgacacaggagaccccgaagagtcattgcccgctaccgctaccagcaagtg gtggtaggaaacgtgcaggatggcctgattaacgtggaagacggagtcagctctctcccc atcaccccagcgcaggcccccctggcaagcccggaaagcctcggttctttgacgtccacc tccgagcaggcccagctggccacctcggaaagcctcagcccactcacttctctctcaggc caggcccccctggccactggagaaagcctgagcgatctcccctccacctcagagcaggcc cggcacagctatggtgttcgctttaatggtttccaggctgatgacagtattattcctacc gaaatccgcaaccgtgtcgaagcccatggccatggtgttacccatgaccatgaagattcc aatgagagcttgagctcggatgagcgccatggccatggccccagtgggaagcccatgctt caccatggcgagaagggtgtgcaagaagcaggctgggaccttgatgacaacaatgacaag agcgactgccttgccattaaggagcaattcaagtgtgatactaacagtacctggggcctt aatgatgatgagctcatggcccatggccaagagaaggacagtagctcagagtctgaggat agttgccccccaagccctgggtgctccttcactgaagggttctccttcgatctctttaat cctgactacgtcccaaaggtcgacaagtggtcccggttcctcttccctctggcctttggg ttgttcaacattgtttactgggtataccatatgtattag

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