PATHWAY: ko00650 Help Entry ko00650                     Pathway                                 Name Butanoate metabolism Class Metabolism; Carbohydrate metabolism BRITE hierarchy Pathway map ko00650   Butanoate metabolism Module M00027   GABA (gamma-Aminobutyrate) shunt [PATH:ko00650] M00088   Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone [PATH:ko00650] Other DBs GO:  0019605 Orthology K00004   BDH, butB; (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303] K00019   BDH1, bdhA; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] K00022   HADH; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] K00023   phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] K00043   gbd; 4-hydroxybutyrate dehydrogenase [EC:1.1.1.61] K00074   paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] K00100   bdhAB; butanol dehydrogenase [EC:1.1.1.-] K00109   L2HGDH; 2-hydroxyglutarate dehydrogenase [EC:1.1.99.2] K00132   E1.2.1.10; acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10] K00135   gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] K00139   ALDH5A1; succinate-semialdehyde dehydrogenase [EC:1.2.1.24] K00169   porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] K00170   porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] K00171   porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] K00172   porC, porG; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] K00174   korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] K00175   korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] K00189   vorG, porG; 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1] K00209   fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] K00233   frdA, fdrA; succinate dehydrogenase flavoprotein subunit K00239   sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] K00240   sdhB, frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] K00241   sdhC, frdC; succinate dehydrogenase cytochrome b subunit K00242   sdhD, frdD; succinate dehydrogenase membrane anchor subunit K00244   frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] K00245   frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] K00246   frdC; succinate dehydrogenase subunit C K00247   frdD; succinate dehydrogenase subunit D K00248   ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] K00626   ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] K00634   ptb; phosphate butyryltransferase [EC:2.3.1.19] K00656   E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] K00823   puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] K00929   buk; butyrate kinase [EC:2.7.2.7] K01027   OXCT; 3-oxoacid CoA-transferase [EC:2.8.3.5] K01028   scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] K01029   scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] K01034   atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] K01035   atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] K01039   gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12] K01040   gctB; glutaconate CoA-transferase, subunit B [EC:2.8.3.12] K01574   adc; acetoacetate decarboxylase [EC:4.1.1.4] K01575   alsD, budA, aldC; acetolactate decarboxylase [EC:4.1.1.5] K01580   E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15] K01615   gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] K01640   HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] K01641   HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] K01652   E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] K01653   E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6] K01692   paaF, echA; enoyl-CoA hydratase [EC:4.2.1.17] K01715   crt; enoyl-CoA hydratase [EC:4.2.1.17] K01782   fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] K01799   nicE, maiA; maleate isomerase [EC:5.2.1.1] K01825   fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] K01896   ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] K01907   AACS, acsA; acetoacetyl-CoA synthetase [EC:6.2.1.16] K01913   AAE7, ACN1; acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2] K03366   butA, budC; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] K03737   por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] K03821   phaC, phbC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] K04072   adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] K04073   mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] K05973   phaZ; poly(3-hydroxybutyrate) depolymerase [EC:3.1.1.75] K07246   ttuC, dmlA; tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83] K07250   gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] K07511   ECHS1; enoyl-CoA hydratase [EC:4.2.1.17] K07514   EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8] K07515   HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] K07516   fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] K07518   E3.1.1.22; hydroxybutyrate-dimer hydrolase [EC:3.1.1.22] K08318   yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase [EC:1.1.1.61 1.1.1.373] K08324   sad; succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24] K11258   ilvM; acetolactate synthase II small subunit [EC:2.2.1.6] K13524   ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] K14268   davT, gabT; 5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19] K14534   abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] K16871   POP2; 4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96] K17761   SSADH; succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24] K17829   ccrA; crotonyl-CoA reductase [EC:1.3.1.86] K17865   croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55] K18009   budC; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] K18118   aarC, cat1; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] K18119   sucD; succinate-semialdehyde dehydrogenase [EC:1.2.1.76] K18120   4hbD, abfH; 4-hydroxybutyrate dehydrogenase [EC:1.1.1.61] K18121   GLYR; glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-] K18122   cat2, abfT; 4-hydroxybutyrate CoA-transferase [EC:2.8.3.-] K18223   prmA; propane 2-monooxygenase large subunit [EC:1.14.13.227] K18224   prmC; propane 2-monooxygenase small subunit [EC:1.14.13.227] K18225   prmB; propane monooxygenase reductase component [EC:1.18.1.-] K18226   prmD; propane monooxygenase coupling protein K18366   bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87] K18369   adh2; alcohol dehydrogenase [EC:1.1.1.-] K18370   adh3; alcohol dehydrogenase [EC:1.1.1.-] K18371   acmA; acetone monooxygenase (methyl acetate-forming) [EC:1.14.13.226] K18372   acmB; methyl acetate hydrolase [EC:3.1.1.114] K18382   adh1; NAD+-dependent secondary alcohol dehydrogenase Adh1 [EC:1.1.1.-] K18859   sdhD, frdD; succinate dehydrogenase subunit D K18860   sdhD, frdD; succinate dehydrogenase subunit D K19709   ydiF; acetate CoA-transferase [EC:2.8.3.8] K20509   madB, oadB, gcdB, mmdB; carboxybiotin decarboxylase [EC:7.2.4.1] K21317   bmoX; butane monooxygenase alpha subunit [EC:1.14.13.230] K21318   bmoY; butane monooxygenase beta subunit [EC:1.14.13.230] K21319   bmoZ; butane monooxygenase gamma subunit [EC:1.14.13.230] K21320   bmoC; butane monooxygenase reductase K21321   bmoB; butane monooxygenase regulatory protein K21322   bmoD; butane monooxygenase hypothetical assembly protein K22881   phaE; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE K23259   adh; isopropanol dehydrogenase (NADP+) K23351   gcdC, mmdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma K23352   gcdD, mmdD; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit delta K23756   ACSM1, LAE; medium-chain acyl-CoA ligase / lipoate-activating enzyme K25995   frdB, fdrB; succinate dehydrogenase iron-sulfur subunit K25996   frdC, fdrC; succinate dehydrogenase subunit C K26318   fccA, fcc3; fumarate reductase (cytochrome) Compound C00022   Pyruvate C00024   Acetyl-CoA C00025   L-Glutamate C00026   2-Oxoglutarate C00042   Succinate C00091   Succinyl-CoA C00122   Fumarate C00132   Methanol C00136   Butanoyl-CoA C00164   Acetoacetate C00207   Acetone C00232   Succinate semialdehyde C00246   Butanoic acid C00332   Acetoacetyl-CoA C00334   4-Aminobutanoate C00356   (S)-3-Hydroxy-3-methylglutaryl-CoA C00497   (R)-Malate C00741   Diacetyl C00810   (R)-Acetoin C00877   Crotonoyl-CoA C00989   4-Hydroxybutanoic acid C01089   (R)-3-Hydroxybutanoate C01144   (S)-3-Hydroxybutanoyl-CoA C01384   Maleic acid C01412   Butanal C01769   (S)-Acetoin C01845   Propan-2-ol C02331   Vinylacetyl-CoA C02411   Glutaconyl-1-CoA C02527   Butanoylphosphate C02630   2-Hydroxyglutarate C03044   (R,R)-Butane-2,3-diol C03046   (S,S)-Butane-2,3-diol C03058   2-Hydroxyglutaryl-CoA C03561   (R)-3-Hydroxybutanoyl-CoA C04546   (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate C06010   (S)-2-Acetolactate C06142   1-Butanol C06143   Poly-beta-hydroxybutyrate C06144   3-Butynoate C06145   3-Butyn-1-al C06146   3-Butyn-1-ol C11062   4-Hydroxybutyryl-CoA C17530   Methyl acetate C20657   meso-2,3-Butanediol C20783   Propane C21390   Butane Related pathway ko00010   Glycolysis / Gluconeogenesis ko00020   Citrate cycle (TCA cycle) ko00250   Alanine, aspartate and glutamate metabolism ko00330   Arginine and proline metabolism ko00620   Pyruvate metabolism ko00750   Vitamin B6 metabolism ko01056   Biosynthesis of type II polyketide backbone

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