| mGluR5-Ca2+ -apoptotic pathway |
| Mutation-caused aberrant Abeta to mGluR5-Ca2+ -apoptotic pathway |
| Mutation-caused aberrant PSEN1 to mGluR5-Ca2+ -apoptotic pathway |
| Mutation-caused aberrant PSEN to mGluR5-Ca2+ -apoptotic pathway |
| mAChR-Ca2+ -apoptotic pathway |
| Mutation-caused aberrant Abeta to mAchR-Ca2+ -apoptotic pathway |
| VGCC-Ca2+ -apoptotic pathway |
| Mutation-caused aberrant Abeta to VGCC-Ca2+ -apoptotic pathway |
| Mutation-caused aberrant Abeta to VGCC-Ca2+ -apoptotic pathway |
| Transport of calcium |
| Mutation-caused aberrant Abeta to transport of calcium |
| 26S proteasome-mediated protein degradation |
| Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation |
| PERK-ATF4 signaling pathway |
| Mutation-caused aberrant PSEN1 to PERK-ATF4 signaling pathway |
| IRE1a-XBP1 signaling pathway |
| Mutation-caused aberrant PSEN1 to IRE1a-XBP1 signaling pathway |
| IRE1a-JNK signaling pathway |
| Mutation-caused aberrant Abeta to IRE1a-JNK signaling pathway |
| ATF6-mediated transcription |
| Mutation-caused aberrant PSEN1 to ATF6-mediated transcription |
| Crosstalk between extrinsic and intrinsic apoptotic pathways |
| Mutation-caused aberrant Abeta to crosstalk between extrinsic and intrinsic apoptotic pathways |
| AGE-RAGE signaling pathway |
| Mutation-caused aberrant Abeta to AGE-RAGE signaling pathway |
| Electron transfer in Complex I |
| Mutation-caused aberrant Abeta to electron transfer in Complex I |
| Electron transfer in Complex II |
| Manganese to electron transfer in Complex II |
| Electron transfer in Complex IV |
| Mutation-caused aberrant Abeta to electron transfer in Complex IV |
| Anterograde axonal transport |
| Mutation-caused aberrant PSEN1 to anterograde axonal transport |
| Mutation-caused aberrant Abeta to anterograde axonal transport |
| Zn to anterograde axonal transport |
| Iron to anterograde axonal transport |
| NEP-mediated Abeta degradation |
| Mercury to NEP-mediated Abeta degradation |