KEGG   PATHWAY: cvf00230
Entry
cvf00230                    Pathway                                
Name
Purine metabolism - Charadrius vociferus (killdeer)
Class
Metabolism; Nucleotide metabolism
Pathway map
cvf00230  Purine metabolism
cvf00230

Module
cvf_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cvf00230]
cvf_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cvf00230]
cvf_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cvf00230]
cvf_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cvf00230]
cvf_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cvf00230]
cvf_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cvf00230]
Other DBs
GO: 0006163 0042278
Organism
Charadrius vociferus (killdeer) [GN:cvf]
Gene
104291511  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104284595  NUDT5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104285509  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104288071  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104287266  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
104286444  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104295172  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104295199  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104286445  zinc finger and SCAN domain-containing protein 20-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104286446  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104295525  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104288740  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104290881  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104292584  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104283372  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104290150  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
104281925  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
104282137  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
104284430  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104286728  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
104288685  NT5E; LOW QUALITY PROTEIN: 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104284885  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104282913  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104291202  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104283594  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104293083  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104285573  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
104292220  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
104292292  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
104281722  nucleoside diphosphate kinase isoform X1 [KO:K00940] [EC:2.7.4.6]
104294289  AK9; LOW QUALITY PROTEIN: adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104291075  LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104291111  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104291112  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104281565  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104282381  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
104290142  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
104285650  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
104288197  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104295131  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
104293399  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104283638  XDH; LOW QUALITY PROTEIN: xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104290615  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104285953  GMPS; LOW QUALITY PROTEIN: GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104285689  GMPR; GMP reductase 1 isoform X1 [KO:K00364] [EC:1.7.1.7]
104287673  GDA; guanine deaminase isoform X1 [KO:K01487] [EC:3.5.4.3]
104282410  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
104291581  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104292429  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104293736  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
104282106  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104282030  DGUOK; deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
104287766  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104293144  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104290383  PRUNE; protein prune homolog [KO:K01514] [EC:3.6.1.11]
104295315  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
104285350  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
104295685  ADCY3; LOW QUALITY PROTEIN: adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
104288498  ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
104284823  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
104286482  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104282884  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104283743  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104291666  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
104294134  GUCY1A3; guanylate cyclase soluble subunit alpha-3 isoform X1 [KO:K12318] [EC:4.6.1.2]
104290651  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104294135  GUCY1B3; guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
104295468  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104295306  LOW QUALITY PROTEIN: retinal guanylyl cyclase 2-like [KO:K12321] [EC:4.6.1.2]
104283109  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
104291253  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
104296055  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104287498  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
104281934  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like [KO:K13755] [EC:3.1.4.17]
104286971  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
104281630  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
104291710  PDE3B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104288991  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
104284924  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104289705  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
104284954  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104294743  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104292028  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
104292120  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104294094  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
104289523  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104291682  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
104293473  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
104289676  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
104291078  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104281608  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104292812  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
104283436  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104285540  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
104286131  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104284426  AK2; adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
104289175  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
104288115  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104285777  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
104291066  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
104291868  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104282094  ENPP1; LOW QUALITY PROTEIN: ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104282118  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104285503  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
104285641  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [KO:K13293] [EC:3.1.4.53]
104294645  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
104290655  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
104284013  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
104285748  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
104287417  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
104293062  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
104286887  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
104283494  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104286849  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104286147  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cvf00030  Pentose phosphate pathway
cvf00220  Arginine biosynthesis
cvf00250  Alanine, aspartate and glutamate metabolism
cvf00260  Glycine, serine and threonine metabolism
cvf00340  Histidine metabolism
cvf00630  Glyoxylate and dicarboxylate metabolism
cvf00730  Thiamine metabolism
cvf00740  Riboflavin metabolism
cvf00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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