KEGG   PATHWAY: dnm00230
Entry
dnm00230                    Pathway                                
Name
Purine metabolism - Dasypus novemcinctus (nine-banded armadillo)
Class
Metabolism; Nucleotide metabolism
Pathway map
dnm00230  Purine metabolism
dnm00230

Module
dnm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:dnm00230]
dnm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:dnm00230]
dnm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dnm00230]
dnm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:dnm00230]
dnm_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:dnm00230]
dnm_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:dnm00230]
dnm_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:dnm00230]
Other DBs
GO: 0006163 0042278
Organism
Dasypus novemcinctus (nine-banded armadillo) [GN:dnm]
Gene
101420245  NUDT9; ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
101447474  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
101415921  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
101429089  PGM1; phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
101441136  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
101429771  PRPS2; ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
101430999  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
101419642  PPAT; amidophosphoribosyltransferase isoform X1 [KO:K00764] [EC:2.4.2.14]
101434283  GART; trifunctional purine biosynthetic protein adenosine-3 isoform X2 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
101427444  PFAS; LOW QUALITY PROTEIN: phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
101418600  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
101443405  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
101428227  ATIC; bifunctional purine biosynthesis protein PURH isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
101424632  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
101431888  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
101418733  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
101421269  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial isoform X1 [KO:K01081] [EC:3.1.3.5]
101444101  cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
101413534  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
101422257  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
101422770  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
101438275  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
101428577  HPRT1; hypoxanthine-guanine phosphoribosyltransferase isoform X1 [KO:K00760] [EC:2.4.2.8]
101423234  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
101421582  IMPDH1; inosine-5'-monophosphate dehydrogenase 1 [KO:K00088] [EC:1.1.1.205]
101419278  NME6; nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
101413229  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
101418636  NME2; nucleoside diphosphate kinase B [KO:K00940] [EC:2.7.4.6]
105744143  nucleoside diphosphate kinase A [KO:K00940] [EC:2.7.4.6]
101425901  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
101437959  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X2 [KO:K01510] [EC:3.6.1.5]
101412553  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
101440603  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
101447553  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
101424961  ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
101433129  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
101413456  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
101411803  U8 snoRNA-decapping enzyme [KO:K16855] [EC:3.6.1.62 3.6.1.64]
101423636  ITPA; inosine triphosphate pyrophosphatase isoform X1 [KO:K01519] [EC:3.6.1.66]
101430447  XDH; xanthine dehydrogenase/oxidase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
101425616  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
101440085  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
101442941  GMPR2; GMP reductase 2 isoform X1 [KO:K00364] [EC:1.7.1.7]
101422196  GMPR; GMP reductase 1 isoform X1 [KO:K00364] [EC:1.7.1.7]
101445058  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
101411514  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
101419077  ribonucleoside-diphosphate reductase large chain 1-like [KO:K10807] [EC:1.17.4.1]
101424915  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
101418444  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X1 [KO:K10808] [EC:1.17.4.1]
101440749  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
101440622  ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
101421146  HDDC2; HD domain-containing protein 2 isoform X1 [KO:K07023] [EC:3.1.3.89]
101414555  DGUOK; deoxyguanosine kinase, mitochondrial isoform X1 [KO:K00904] [EC:2.7.1.113]
101427738  DCK; deoxycytidine kinase isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
101436725  HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
101441559  PRUNE1; LOW QUALITY PROTEIN: exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
101411559  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
101411573  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
101419332  ADCY4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
101417345  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
101442950  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
101427927  ADCY7; LOW QUALITY PROTEIN: adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
101422732  adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
101442901  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
101416433  adenylate cyclase type 10-like isoform X2 [KO:K11265] [EC:4.6.1.1]
101421718  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
101422668  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
101415948  GUCY1A1; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
101417247  GUCY1B1; guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
101424080  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
101421088  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
101430783  GUCY2D; retinal guanylyl cyclase 1 [KO:K12321] [EC:4.6.1.2]
101442492  olfactory guanylyl cyclase GC-D-like [KO:K12321] [EC:4.6.1.2]
101417975  GUCY2F; LOW QUALITY PROTEIN: retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
101437109  guanylate cyclase 2G-like [KO:K22600] [EC:4.6.1.2]
101438701  NPR1; LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
101411447  NPR2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
101418622  PDE1B; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1 [KO:K13755] [EC:3.1.4.17]
101434900  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1 [KO:K13755] [EC:3.1.4.17]
101443661  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1 [KO:K13755] [EC:3.1.4.17]
101418634  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
101427262  PDE3A; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
101440531  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
101433448  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
101443907  PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha isoform X1 [KO:K08718] [EC:3.1.4.35]
101424625  rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
101427318  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
101430149  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
101424261  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
101430559  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
101424461  PDE11A; LOW QUALITY PROTEIN: dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
101434792  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
101418486  adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
101439477  AMPD2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
101446690  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
101411102  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
101431202  ADK; adenosine kinase isoform X1 [KO:K00856] [EC:2.7.1.20]
101427075  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
101442794  ADA2; LOW QUALITY PROTEIN: adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
101418405  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
111762335  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
101427834  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
101447614  AK4; LOW QUALITY PROTEIN: adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
101446351  AK8; LOW QUALITY PROTEIN: adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
101429288  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
101439750  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
102314699  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
101437689  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
101441939  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
101436643  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
101425427  LOW QUALITY PROTEIN: ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
101421311  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
101428981  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
101433426  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
101412263  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
101444030  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
101432017  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
101417591  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
101428617  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
101439066  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
101426165  FHIT; bis(5'-adenosyl)-triphosphatase isoform X1 [KO:K01522] [EC:3.6.1.29]
101427821  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
101420244  diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2-like [KO:K00988] [EC:2.7.7.5 2.7.7.53]
101431099  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101444146  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X4 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101420609  uricase [KO:K00365] [EC:1.7.3.3]
101427065  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
101422844  URAD; putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
101439461  ALLC; probable allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
dnm00030  Pentose phosphate pathway
dnm00220  Arginine biosynthesis
dnm00250  Alanine, aspartate and glutamate metabolism
dnm00260  Glycine, serine and threonine metabolism
dnm00340  Histidine metabolism
dnm00630  Glyoxylate and dicarboxylate metabolism
dnm00730  Thiamine metabolism
dnm00740  Riboflavin metabolism
dnm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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