KEGG   PATHWAY: fab00230
Entry
fab00230                    Pathway                                
Name
Purine metabolism - Ficedula albicollis (collared flycatcher)
Class
Metabolism; Nucleotide metabolism
Pathway map
fab00230  Purine metabolism
fab00230

Module
fab_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:fab00230]
fab_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:fab00230]
fab_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:fab00230]
fab_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:fab00230]
fab_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:fab00230]
fab_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:fab00230]
fab_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:fab00230]
Other DBs
GO: 0006163 0042278
Organism
Ficedula albicollis (collared flycatcher) [GN:fab]
Gene
101814794  NUDT9; nudix hydrolase 9 [KO:K13988] [EC:3.6.1.13]
101822214  ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
101811306  NUDT5; nudix hydrolase 5 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
101805676  PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
101821251  PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
101820644  PRPS2; phosphoribosyl pyrophosphate synthetase 2 [KO:K00948] [EC:2.7.6.1]
101818242  PRPS1; phosphoribosyl pyrophosphate synthetase 1 [KO:K00948] [EC:2.7.6.1]
101807950  PPAT; phosphoribosyl pyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
101817498  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
101816412  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
101819461  PFAS; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
101808142  PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
101807763  trihelix transcription factor GT-2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
101812487  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
101815076  ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
101812646  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
101806069  NT5M; 5',3'-nucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
101814241  NT5C; 5', 3'-nucleotidase, cytosolic [KO:K01081] [EC:3.1.3.5]
101811802  NT5C1A; 5'-nucleotidase, cytosolic IA [KO:K01081] [EC:3.1.3.5]
101807190  NT5C1B; cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
101814541  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
101805737  NT5C2; 5'-nucleotidase, cytosolic II [KO:K01081] [EC:3.1.3.5]
101819316  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
101818777  NT5E; 5'-nucleotidase ecto [KO:K19970] [EC:3.1.3.5]
101808682  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
107603312  LACC1; laccase domain containing 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
101813437  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
101818301  HPRT1; hypoxanthine phosphoribosyltransferase 1 [KO:K00760] [EC:2.4.2.8]
101808363  IMPDH2; inosine monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
101807054  NME6; NME/NM23 nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
101811599  NME4; nucleoside diphosphate kinase, mitochondrial [KO:K00940] [EC:2.7.4.6]
101807788  NME3; NME/NM23 nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
101818215  NME7; NME/NM23 family member 7 [KO:K00940] [EC:2.7.4.6]
107603315  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
101806316  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
101810659  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
101809481  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
101809685  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
101818198  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
101806865  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
101817605  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
101811604  CANT1; calcium activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
101814697  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
101814014  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 (putative) [KO:K01511] [EC:3.6.1.6]
101820141  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
101821134  ITPA; inosine triphosphatase [KO:K01519] [EC:3.6.1.66]
101819038  XDH; xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
101813659  NUDT2; nudix hydrolase 2 [KO:K01518] [EC:3.6.1.17]
101806119  GMPS; guanine monophosphate synthase [KO:K01951] [EC:6.3.5.2]
101814461  GMPR; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
101809949  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
101811045  GUK1; guanylate kinase 1 [KO:K00942] [EC:2.7.4.8]
101812731  RRM1; ribonucleotide reductase catalytic subunit M1 [KO:K10807] [EC:1.17.4.1]
101815464  RRM2; ribonucleotide reductase regulatory subunit M2 [KO:K10808] [EC:1.17.4.1]
101819545  RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B [KO:K10808] [EC:1.17.4.1]
101805654  HDDC2; HD domain containing 2 [KO:K07023] [EC:3.1.3.89]
101821686  DGUOK; deoxyguanosine kinase [KO:K00904] [EC:2.7.1.113]
101806066  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
101811376  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
101812447  HDDC3; HD domain containing 3 [KO:K21138] [EC:3.1.7.2]
101807752  ADCY1; adenylate cyclase 1 [KO:K08041] [EC:4.6.1.1]
101808400  ADCY2; adenylate cyclase 2 [KO:K08042] [EC:4.6.1.1]
101807084  ADCY5; adenylate cyclase 5 [KO:K08045] [EC:4.6.1.1]
101810909  ADCY6; adenylate cyclase 6 [KO:K08046] [EC:4.6.1.1]
101816007  ADCY7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
101809046  ADCY8; adenylate cyclase 8 [KO:K08048] [EC:4.6.1.1]
101818533  ADCY9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
101814320  GUCY1A3; guanylate cyclase 1 soluble subunit alpha [KO:K12318] [EC:4.6.1.2]
101812872  GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2 [KO:K12318] [EC:4.6.1.2]
101815504  GUCY1B3; guanylate cyclase 1 soluble subunit beta [KO:K12319] [EC:4.6.1.2]
101818523  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
101816039  GUCY2C; guanylate cyclase 2C [KO:K12320] [EC:4.6.1.2]
101816994  GUCY2F; guanylate cyclase 2F, retinal [KO:K12322] [EC:4.6.1.2]
101807229  NPR2; natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
101821431  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
101815759  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like [KO:K13755] [EC:3.1.4.17]
101814144  PDE1C; phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
101820223  PDE1A; phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
101813085  PDE2A; phosphodiesterase 2A [KO:K18283] [EC:3.1.4.17]
101808899  PDE3A; phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
101814223  PDE3B; phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
101812823  PDE5A; phosphodiesterase 5A [KO:K13762] [EC:3.1.4.35]
101811029  PDE6B; phosphodiesterase 6B [KO:K13756] [EC:3.1.4.35]
101810613  PDE6C; phosphodiesterase 6C [KO:K13757] [EC:3.1.4.35]
101814810  PDE6D; phosphodiesterase 6D [KO:K13758]
101816272  PDE6G; phosphodiesterase 6G [KO:K13759]
101805910  PDE6H; phosphodiesterase 6H [KO:K13760]
101817898  PDE9A; phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
101817395  PDE10A; phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
101817023  PDE11A; phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
101807309  ADSS; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
101814672  ADSSL1; adenylosuccinate synthase like 1 [KO:K01939] [EC:6.3.4.4]
101813859  AMPD1; adenosine monophosphate deaminase 1 [KO:K01490] [EC:3.5.4.6]
101814909  AMPD2; adenosine monophosphate deaminase 2 [KO:K01490] [EC:3.5.4.6]
101820483  AMPD3; adenosine monophosphate deaminase 3 [KO:K01490] [EC:3.5.4.6]
101811843  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
101821624  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
101814854  CECR1; cat eye syndrome chromosome region, candidate 1 [KO:K19572] [EC:3.5.4.4]
101817676  AK1; adenylate kinase 1 [KO:K00939] [EC:2.7.4.3]
101814247  AK2; adenylate kinase 2 [KO:K00939] [EC:2.7.4.3]
101806187  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
101813164  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
101813491  AK4; adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
101813900  AK5; adenylate kinase 5 [KO:K00939] [EC:2.7.4.3]
101813137  AK6; adenylate kinase 6 [KO:K18532] [EC:2.7.4.3]
101808054  AK3; adenylate kinase 3 [KO:K00944] [EC:2.7.4.10]
101819835  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
101817327  NTPCR; nucleoside-triphosphatase, cancer-related [KO:K06928] [EC:3.6.1.15]
101806551  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
101807371  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
101812864  PDE4C; phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
101806560  PDE4B; phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
101809494  PDE4D; phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
101806938  PDE7A; phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
101820600  PDE7B; phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
101808501  PDE8B; phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
101812446  PDE8A; phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
101821344  FHIT; fragile histidine triad [KO:K01522] [EC:3.6.1.29]
101806945  ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) [KO:K18424] [EC:3.6.1.29]
101821854  PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101807769  PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101806442  uricase-like [KO:K00365] [EC:1.7.3.3]
101806503  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
fab00030  Pentose phosphate pathway
fab00220  Arginine biosynthesis
fab00250  Alanine, aspartate and glutamate metabolism
fab00260  Glycine, serine and threonine metabolism
fab00340  Histidine metabolism
fab00630  Glyoxylate and dicarboxylate metabolism
fab00730  Thiamine metabolism
fab00740  Riboflavin metabolism
fab00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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