KEGG   PATHWAY: gcl00230
Entry
gcl00230                    Pathway                                
Name
Purine metabolism - Gymnogyps californianus (California condor)
Class
Metabolism; Nucleotide metabolism
Pathway map
gcl00230  Purine metabolism
gcl00230

Module
gcl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:gcl00230]
gcl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:gcl00230]
gcl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:gcl00230]
gcl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:gcl00230]
gcl_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:gcl00230]
gcl_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:gcl00230]
Other DBs
GO: 0006163 0042278
Organism
Gymnogyps californianus (California condor) [GN:gcl]
Gene
127015702  ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
127024080  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
127015891  ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
127018900  phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
127015755  phosphopentomutase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
127017792  ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
127019617  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
127015554  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
127029447  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
127029448  LOW QUALITY PROTEIN: trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
127015555  bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
127015129  adenylosuccinate lyase isoform X1 [KO:K01756] [EC:4.3.2.2]
127018297  bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
127021321  adenine phosphoribosyltransferase isoform X1 [KO:K00759] [EC:2.4.2.7]
127016889  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
127022542  5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
127017762  cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
127025365  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
127014341  cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
127024045  5'(3')-deoxyribonucleotidase, cytosolic type isoform X1 [KO:K01081] [EC:3.1.3.5]
127014509  5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
127021249  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
127019586  purine nucleoside phosphorylase LACC1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
127019678  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
127021049  LOW QUALITY PROTEIN: hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
127021768  inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
127022479  LOW QUALITY PROTEIN: nucleoside diphosphate kinase, mitochondrial-like [KO:K00940] [EC:2.7.4.6]
127022481  nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
127017531  nucleoside diphosphate kinase 7 isoform X1 [KO:K00940] [EC:2.7.4.6]
127023009  LOW QUALITY PROTEIN: nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
127024069  nucleoside diphosphate kinase isoform X1 [KO:K00940] [EC:2.7.4.6]
127014528  LOW QUALITY PROTEIN: adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
127017597  ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
127013635  LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
127023735  LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
127023751  ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
127023826  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
127024047  soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
127025317  ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
127017376  nucleoside diphosphate phosphatase ENTPD5 [KO:K01511] [EC:3.6.1.6]
127014141  ectonucleoside triphosphate diphosphohydrolase 6 isoform X1 [KO:K01511] [EC:3.6.1.6]
127019193  LOW QUALITY PROTEIN: inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
127014229  xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
127027569  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
127020077  GMP synthase [glutamine-hydrolyzing] isoform X1 [KO:K01951] [EC:6.3.5.2]
127013587  GMP reductase 1 isoform X1 [KO:K00364] [EC:1.7.1.7]
127027384  guanine deaminase [KO:K01487] [EC:3.5.4.3]
127012986  guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
127025327  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
127013606  ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
127015144  ribonucleoside-diphosphate reductase subunit M2 isoform X1 [KO:K10808] [EC:1.17.4.1]
127014507  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
127025281  deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
127022084  deoxycytidine kinase 2 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
127015772  deoxycytidine kinase isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
127027007  exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
127013036  adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
127012822  adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
127014701  adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
127018137  adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
127021006  adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
127013867  LOW QUALITY PROTEIN: adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
127022660  adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
127027988  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
127027990  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
127027991  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
127016108  guanylate cyclase soluble subunit alpha-1 isoform X1 [KO:K12318] [EC:4.6.1.2]
127022000  guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
127020173  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
127015579  guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
127020940  guanylyl cyclase C [KO:K12320] [EC:4.6.1.2]
127028159  LOW QUALITY PROTEIN: retinal guanylyl cyclase 2-like [KO:K12322] [EC:4.6.1.2]
127027225  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
127018266  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
127029957  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
127017744  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
127016579  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
127016299  cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13762] [EC:3.1.4.35]
127027551  rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
127017909  cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X1 [KO:K13757] [EC:3.1.4.35]
127020041  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform X1 [KO:K13758]
127029317  retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
127016451  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
127014393  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
127018461  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
127016683  adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
127014288  adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
127016861  AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
127026182  AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
127026241  AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
127017910  adenosine kinase isoform X1 [KO:K00856] [EC:2.7.1.20]
127023148  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
127023365  adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
127016712  adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
127024974  adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
127019093  adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
127019335  adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
127023676  adenylate kinase 8 isoform X1 [KO:K00939] [EC:2.7.4.3]
127023708  adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
127027387  adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
127027074  GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [KO:K00944] [EC:2.7.4.10]
127023740  ectonucleoside triphosphate diphosphohydrolase 2 isoform X1 [KO:K01509] [EC:3.6.1.-]
127014466  cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
127014980  LOW QUALITY PROTEIN: ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
127014981  ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
127025699  LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
127018863  cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
127027260  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
127029050  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [KO:K13293] [EC:3.1.4.53]
127012866  high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
127014326  cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
127027106  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
127020444  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 [KO:K18437] [EC:3.1.4.53]
127029043  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like [KO:K18437] [EC:3.1.4.53]
127021531  bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
127013975  bis(5'-adenosyl)-triphosphatase ENPP4 isoform X1 [KO:K18424] [EC:3.6.1.29]
127017864  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
127015662  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
127019105  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
gcl00030  Pentose phosphate pathway
gcl00220  Arginine biosynthesis
gcl00250  Alanine, aspartate and glutamate metabolism
gcl00260  Glycine, serine and threonine metabolism
gcl00340  Histidine metabolism
gcl00630  Glyoxylate and dicarboxylate metabolism
gcl00730  Thiamine metabolism
gcl00740  Riboflavin metabolism
gcl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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