KEGG   PATHWAY: oha00230
Entry
oha00230                    Pathway                                
Name
Purine metabolism - Opisthocomus hoazin (hoatzin)
Class
Metabolism; Nucleotide metabolism
Pathway map
oha00230  Purine metabolism
oha00230

Module
oha_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:oha00230]
oha_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:oha00230]
oha_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:oha00230]
oha_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:oha00230]
oha_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:oha00230]
oha_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:oha00230]
Other DBs
GO: 0006163 0042278
Organism
Opisthocomus hoazin (hoatzin) [GN:oha]
Gene
104327379  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
104337624  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
104326398  PGM1; LOW QUALITY PROTEIN: phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
104330320  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
104329564  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
104337540  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
104334929  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
104328348  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104328369  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
104334899  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
104329869  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
104327806  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104329139  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
104330164  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
104332042  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
104332859  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
104335323  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
104335676  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
104336199  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
104330420  NT5E; LOW QUALITY PROTEIN: 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
104328625  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
104336932  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
104339190  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
104335731  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104331355  IMPDH2; LOW QUALITY PROTEIN: inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
104333924  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
104335175  nucleoside diphosphate kinase isoform X1 [KO:K00940] [EC:2.7.4.6]
104336112  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
104329182  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
104332642  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
104338194  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
104338627  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104338629  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104338630  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
104339561  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
104333604  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
104333757  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
104331955  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104337949  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
104336559  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104333857  GMPR; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
104333378  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
104326610  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
104339483  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104332116  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
104336256  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
104327087  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104330338  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104326914  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
104334085  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
104337731  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
104334752  ADCY3; LOW QUALITY PROTEIN: adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
104337463  ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
104338983  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
104335886  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
104331018  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
104333064  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
104331610  GUCY1A3; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
104337981  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
104331609  GUCY1B3; guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
104329897  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
104334686  retinal guanylyl cyclase 2-like [KO:K12321] [EC:4.6.1.2]
104326270  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
104338373  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
104337162  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1 [KO:K13755] [EC:3.1.4.17]
104339449  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
104333608  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
104338088  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
104330139  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
104331246  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
104333546  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
104330450  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
104326440  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
104334493  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
104327699  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
104331769  PDE10A; LOW QUALITY PROTEIN: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
104329021  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
104336339  ADSS; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
104326497  AMPD3; LOW QUALITY PROTEIN: AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
104333532  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104336379  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
104335775  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
104328826  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
104330254  CECR1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
104327216  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
104329635  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
104330542  adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
104338430  AK2; adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
104338818  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
104331560  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
104329748  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
104330778  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
104329739  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
104329192  NTPCR; cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104327096  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104327097  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104327206  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
104337715  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
104327106  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
104330545  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
104334609  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
104331366  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
104339144  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
104330394  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104327263  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104338833  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
oha00030  Pentose phosphate pathway
oha00220  Arginine biosynthesis
oha00250  Alanine, aspartate and glutamate metabolism
oha00260  Glycine, serine and threonine metabolism
oha00340  Histidine metabolism
oha00630  Glyoxylate and dicarboxylate metabolism
oha00730  Thiamine metabolism
oha00740  Riboflavin metabolism
oha00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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