KEGG   PATHWAY: pcoc00230
Entry
pcoc00230                   Pathway                                
Name
Purine metabolism - Phasianus colchicus (Ring-necked pheasant)
Class
Metabolism; Nucleotide metabolism
Pathway map
pcoc00230  Purine metabolism
pcoc00230

Module
pcoc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pcoc00230]
pcoc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pcoc00230]
pcoc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pcoc00230]
pcoc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pcoc00230]
pcoc_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pcoc00230]
pcoc_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pcoc00230]
Other DBs
GO: 0006163 0042278
Organism
Phasianus colchicus (Ring-necked pheasant) [GN:pcoc]
Gene
116231093  NUDT9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
116235560  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
116242624  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
116235516  PGM1; phosphoglucomutase-1 isoform X1 [KO:K01835] [EC:5.4.2.2]
116225850  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
116230745  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
116229556  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
116225926  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
116241974  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
116241995  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
116225927  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
116233373  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
116236058  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
116243928  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
116243050  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
116237358  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
116231657  NT5C2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
116240469  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
116229942  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
116231320  cytosolic purine 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
116240721  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
116243882  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
116244166  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
116243664  hypoxanthine-guanine phosphoribosyltransferase-like isoform X1 [KO:K00760] [EC:2.4.2.8]
116229631  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
116237464  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
116230290  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
116230292  nucleoside diphosphate kinase, mitochondrial-like [KO:K00940] [EC:2.7.4.6]
116232403  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
116232404  nucleoside diphosphate kinase-like isoform X1 [KO:K00940] [EC:2.7.4.6]
116238653  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
116242439  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
116240769  AK9; adenylate kinase 9 isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
116231740  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
116227146  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
116234124  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
116234125  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
116234420  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
116232535  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
116238379  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
116231490  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
116229389  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 isoform X1 [KO:K01511] [EC:3.6.1.6]
116240186  U8 snoRNA-decapping enzyme-like [KO:K16855] [EC:3.6.1.62 3.6.1.64]
116230496  ITPA; inosine triphosphate pyrophosphatase isoform X1 [KO:K01519] [EC:3.6.1.66]
116235286  XDH; xanthine dehydrogenase/oxidase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
116235461  GMPS; GMP synthase [glutamine-hydrolyzing] isoform X1 [KO:K01951] [EC:6.3.5.2]
116226475  GMPR; GMP reductase 1 isoform X1 [KO:K00364] [EC:1.7.1.7]
116238854  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
116238300  GUK1; guanylate kinase [KO:K00942] [EC:2.7.4.8]
116232705  RRM1; ribonucleoside-diphosphate reductase large subunit isoform X1 [KO:K10807] [EC:1.17.4.1]
116227540  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
116240611  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
116240606  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
116234496  DGUOK; deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
116231179  DCK; deoxycytidine kinase isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
116232174  deoxycytidine kinase-like isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
116238458  PRUNE1; exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
116228264  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
116226507  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
116235620  ADCY3; LOW QUALITY PROTEIN: adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
116227376  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
116243930  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
116227752  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
116230251  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
116243161  GUCY1A1; guanylate cyclase soluble subunit alpha-1 [KO:K12318] [EC:4.6.1.2]
116237203  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
116243134  GUCY1B1; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
116230814  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
116233426  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
116233919  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
116239573  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
116239692  NPR2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
116239745  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
116238585  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1 [KO:K13755] [EC:3.1.4.17]
116239665  PDE1B; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
116234036  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1 [KO:K13755] [EC:3.1.4.17]
116236479  PDE2A; LOW QUALITY PROTEIN: cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
116231824  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
116242987  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
116231237  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
116239293  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
116231771  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
116235378  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
116232507  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
116233242  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
116229890  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
116242196  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
116234054  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
116228681  ADSS2; adenylosuccinate synthetase isozyme 2 isoform X1 [KO:K01939] [EC:6.3.4.4]
116228801  ADSS1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
116243043  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
116236991  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
116238752  AMPD2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
116235079  ADK; adenosine kinase isoform X1 [KO:K00856] [EC:2.7.1.20]
116227487  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
116226871  ADA2; adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
116233638  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
116234194  AK1; adenylate kinase isoenzyme 1 isoform X1 [KO:K00939] [EC:2.7.4.3]
116234281  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
116228869  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
116229951  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
116235615  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
116235321  AK6; adenylate kinase isoenzyme 6 isoform X1 [KO:K18532] [EC:2.7.4.3]
116237164  AK3; GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [KO:K00944] [EC:2.7.4.10]
116234103  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
116228175  NTPCR; cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
116240226  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
116240237  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
116235875  PDE4C; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
116236680  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
116235653  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
116240443  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
116242221  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
116225339  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
116239905  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
116237313  FHIT; bis(5'-adenosyl)-triphosphatase isoform X1 [KO:K01522] [EC:3.6.1.29]
116236337  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
116238045  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
116234766  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
116233357  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pcoc00030  Pentose phosphate pathway
pcoc00220  Arginine biosynthesis
pcoc00250  Alanine, aspartate and glutamate metabolism
pcoc00260  Glycine, serine and threonine metabolism
pcoc00340  Histidine metabolism
pcoc00630  Glyoxylate and dicarboxylate metabolism
pcoc00730  Thiamine metabolism
pcoc00740  Riboflavin metabolism
pcoc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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