KEGG   PATHWAY: pswi04070
Entry
pswi04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Pseudoliparis swirei (Mariana hadal snailfish)
Class
Environmental Information Processing; Signal transduction
Pathway map
pswi04070  Phosphatidylinositol signaling system
pswi04070

Organism
Pseudoliparis swirei (Mariana hadal snailfish) [GN:pswi]
Gene
130197100  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b [KO:K00888] [EC:2.7.1.67]
130204925  pi4kaa; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
130212760  pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
130212784  phosphatidylinositol 4-kinase beta-like isoform X1 [KO:K19801] [EC:2.7.1.67]
130190307  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha isoform X1 [KO:K13711] [EC:2.7.1.67]
130190483  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
130193293  sacm1la; phosphatidylinositol-3-phosphatase SAC1-A isoform X1 [KO:K21797] [EC:3.1.3.-]
130206056  phosphatidylinositol-3-phosphatase SAC1-B isoform X1 [KO:K21797] [EC:3.1.3.-]
130207646  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
130193040  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like isoform X1 [KO:K00889] [EC:2.7.1.68]
130193444  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
130205706  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a isoform X1 [KO:K00889] [EC:2.7.1.68]
130212698  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68]
130197449  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
130198327  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like isoform X1 [KO:K00889] [EC:2.7.1.68]
130209610  ocrl; inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
130212620  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
130196814  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
130209948  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
130193754  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
130199948  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
130198080  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
130210442  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
130212043  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like isoform X1 [KO:K00922] [EC:2.7.1.153]
130193807  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
130194122  phosphatidylinositol 3-kinase regulatory subunit beta-like [KO:K02649]
130196195  phosphatidylinositol 3-kinase regulatory subunit alpha-like [KO:K02649]
130197660  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
130197673  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
130205168  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
130207033  ptena; phosphatase and tensin homolog A isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
130193600  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
130209820  inppl1b; inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
130211372  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
130189745  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
130200600  inpp4aa; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
130204375  inpp4ab; inositol polyphosphate-4-phosphatase type I Ab isoform X1 [KO:K01109] [EC:3.1.3.66]
130202918  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
130211799  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
130213208  mtmr2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
130211594  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
130213316  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
130197411  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
130190584  myotubularin-related protein 7-like isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
130206191  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
130209227  myotubularin-related protein 7-like isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
130210092  myotubularin-related protein 7-like [KO:K18083] [EC:3.1.3.64 3.1.3.95]
130208068  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
130189907  phosphatidylinositol 5-phosphate 4-kinase type-2 beta-like isoform X1 [KO:K00920] [EC:2.7.1.149]
130206018  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
130208470  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like isoform X1 [KO:K00920] [EC:2.7.1.149]
130199817  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
130190971  pip4p1a; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A [KO:K13084] [EC:3.1.3.78]
130195707  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
130211903  type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A-like [KO:K13084] [EC:3.1.3.78]
130211865  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
130194940  pik3c2a; LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
130195365  pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
130207890  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
130207272  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like [KO:K05858] [EC:3.1.4.11]
130201430  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
130202601  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
130202605  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
130211644  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
130188904  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
130205909  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
130206011  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
130203143  plcd3b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
130197550  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like isoform X1 [KO:K05857] [EC:3.1.4.11]
130204614  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
130204107  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
130193629  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like isoform X1 [KO:K01116] [EC:3.1.4.11]
130199481  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
130195679  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
130195366  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
130203280  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
130201321  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
130202830  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
130209828  si:ch73-22a13.3; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
130210278  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
130213190  itpkca; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
130207478  inositol polyphosphate-5-phosphatase A-like isoform X1 [KO:K01106] [EC:3.1.3.56]
130202045  itpk1b; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
130210982  inositol-tetrakisphosphate 1-kinase-like isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
130207788  ippk; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
130208288  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
130208931  ip6k1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
130209037  inositol hexakisphosphate kinase 2-like [KO:K07756] [EC:2.7.4.21]
130192992  ppip5k1a; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
130194873  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
130208997  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
130190934  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
130206241  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
130206242  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
130198076  bpnt2; inositol monophosphatase 3 isoform X1 [KO:K15759] [EC:3.1.3.7]
130190400  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
130195031  dgkzb; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
130212700  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
130200453  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
130201305  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
130208950  dgkab; diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
130203365  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
130209797  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
130204220  diacylglycerol kinase zeta-like [KO:K00901] [EC:2.7.1.107]
130199764  dgkaa; diacylglycerol kinase, alpha a isoform X1 [KO:K00901] [EC:2.7.1.107]
130196844  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
130197304  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
130188660  CDP-diacylglycerol--inositol 3-phosphatidyltransferase-like [KO:K00999] [EC:2.7.8.11]
130188666  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
130208063  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
130208604  inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
130194653  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
130199889  itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
130188951  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
130189644  protein kinase C alpha type-like [KO:K02677] [EC:2.7.11.13]
130190241  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
130188608  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
130213123  prkcg; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
130192292  calml4a; calmodulin-like protein 4a [KO:K02183]
130206962  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
130201284  calm1a; calmodulin-1a [KO:K02183]
130203085  calmodulin-1 [KO:K02183]
130210556  calm3a; calmodulin 3a (phosphorylase kinase, delta) [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
pswi04020  Calcium signaling pathway
pswi04144  Endocytosis
pswi04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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