KEGG   PATHWAY: scan00230
Entry
scan00230                   Pathway                                
Name
Purine metabolism - Serinus canaria (common canary)
Class
Metabolism; Nucleotide metabolism
Pathway map
scan00230  Purine metabolism
scan00230

Module
scan_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:scan00230]
scan_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:scan00230]
scan_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:scan00230]
scan_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:scan00230]
scan_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:scan00230]
scan_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:scan00230]
Other DBs
GO: 0006163 0042278
Organism
Serinus canaria (common canary) [GN:scan]
Gene
103826094  NUDT9; ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
103823912  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
103813570  NUDT5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
103815068  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
103824722  PGM2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
103815806  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
103824237  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
103826193  PPAT; amidophosphoribosyltransferase isoform X1 [KO:K00764] [EC:2.4.2.14]
103824404  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
103824418  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
103825290  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
103826194  trihelix transcription factor PTL isoform X1 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
103813281  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
103814578  ATIC; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
103816888  APRT; LOW QUALITY PROTEIN: adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
103813849  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
103817843  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
103820752  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
103819841  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
103823558  NT5C1A; cytosolic 5'-nucleotidase 1A isoform X1 [KO:K01081] [EC:3.1.3.5]
103826746  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
103822721  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
103822426  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
103816832  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
115484136  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
103812580  LACC1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
103816789  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
103824492  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
103817188  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
115485173  LOW QUALITY PROTEIN: inosine-5'-monophosphate dehydrogenase 1b-like [KO:K00088] [EC:1.1.1.205]
103817936  nucleoside diphosphate kinase, mitochondrial isoform X2 [KO:K00940] [EC:2.7.4.6]
103819810  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
103819811  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
103827072  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
103817952  nucleoside diphosphate kinase 3 isoform X1 [KO:K00940] [EC:2.7.4.6]
103822490  NME6; nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
103822207  adenylate kinase 9 isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
108962491  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
108962522  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
103819192  ectonucleoside triphosphate diphosphohydrolase 8 isoform X2 [KO:K01510] [EC:3.6.1.5]
103813899  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
103812958  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
103819741  CANT1; soluble calcium-activated nucleotidase 1 isoform X2 [KO:K12304] [EC:3.6.1.6]
103824429  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
103821292  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
103826533  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
103823409  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
103821303  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
103820656  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
103815258  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
103812567  GMPR; GMP reductase 1 isoform X1 [KO:K00364] [EC:1.7.1.7]
103822863  GDA; guanine deaminase isoform X1 [KO:K01487] [EC:3.5.4.3]
103812681  GUK1; guanylate kinase isoform X2 [KO:K00942] [EC:2.7.4.8]
103823822  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
103820481  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
103813925  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
103821982  HDDC2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
103824908  DGUOK; deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
103817288  deoxycytidine kinase-like isoform X2 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
103823424  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
115484608  PRUNE1; exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
103819377  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
103815408  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
103814312  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
103824610  ADCY6; LOW QUALITY PROTEIN: adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
103816806  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
103816719  ADCY8; adenylate cyclase type 8 isoform X2 [KO:K08048] [EC:4.6.1.1]
103817765  ADCY9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
103812526  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
103825957  GUCY1A1; guanylate cyclase soluble subunit alpha-1 [KO:K12318] [EC:4.6.1.2]
103815438  guanylate cyclase soluble subunit beta-2-like isoform X1 [KO:K12319] [EC:4.6.1.2]
103825956  GUCY1B1; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
103813321  GUCY2C; heat-stable enterotoxin receptor [KO:K12320] [EC:4.6.1.2]
103812495  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
103822923  atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
103821848  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
103814470  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1 [KO:K13755] [EC:3.1.4.17]
103821175  LOW QUALITY PROTEIN: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
103820746  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
103820531  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X2 [KO:K19021] [EC:3.1.4.17]
103827031  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
103821405  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X5 [KO:K13762] [EC:3.1.4.35]
103821225  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
103813920  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X1 [KO:K13757] [EC:3.1.4.35]
103815358  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform X1 [KO:K13758]
103813370  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
103815750  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
103823797  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
103814704  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
103821862  ADSS2; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
103826864  ADSS1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
103826803  AMPD3; AMP deaminase 3 isoform X2 [KO:K01490] [EC:3.5.4.6]
103822327  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
103822425  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
103814002  ADK; adenosine kinase isoform X1 [KO:K00856] [EC:2.7.1.20]
103818803  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
103820464  ADA2; LOW QUALITY PROTEIN: adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
103819136  AK8; adenylate kinase 8 isoform X3 [KO:K00939] [EC:2.7.4.3]
103814943  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
103819041  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
103823491  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
103826881  AK7; adenylate kinase 7 isoform X1 [KO:K00939] [EC:2.7.4.3]
103815219  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
103823077  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
103823834  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
103819090  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 isoform X1 [KO:K01509] [EC:3.6.1.-]
103818513  NTPCR; cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
103820607  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
103820540  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
103815075  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4 [KO:K13293] [EC:3.1.4.53]
103821042  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
103824707  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
103818461  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
103812663  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X3 [KO:K18436] [EC:3.1.4.53]
103816039  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2 [KO:K18437] [EC:3.1.4.53]
103819496  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
103817068  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
103821119  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
103814226  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
103826012  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
103815159  uricase-like isoform X2 [KO:K00365] [EC:1.7.3.3]
103816903  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
scan00030  Pentose phosphate pathway
scan00220  Arginine biosynthesis
scan00250  Alanine, aspartate and glutamate metabolism
scan00260  Glycine, serine and threonine metabolism
scan00340  Histidine metabolism
scan00630  Glyoxylate and dicarboxylate metabolism
scan00730  Thiamine metabolism
scan00740  Riboflavin metabolism
scan00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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