KEGG   PATHWAY: ppam04070
Entry
ppam04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Pteronotus mesoamericanus (Parnell's mustached bat)
Class
Environmental Information Processing; Signal transduction
Pathway map
ppam04070  Phosphatidylinositol signaling system
ppam04070

Organism
Pteronotus mesoamericanus (Parnell's mustached bat) [GN:ppam]
Gene
129061702  INPP1; inositol polyphosphate 1-phosphatase isoform X1 [KO:K01107] [EC:3.1.3.57]
129062100  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
129062286  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
129062315  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
129062335  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
129063259  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
129063295  DGKI; LOW QUALITY PROTEIN: diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
129063384  DGKB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
129064049  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
129064066  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
129064297  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
129064397  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
129064861  MTMR7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
129065113  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
129065634  CALM2; calmodulin-2 [KO:K02183]
129065815  ITPK1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
129065835  CALM1; calmodulin-1 [KO:K02183]
129067386  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
129067388  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
129067876  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
129068532  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
129068613  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
129068888  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
129069321  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
129069407  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
129069750  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
129069976  IPMK; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
129070029  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
129070225  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
129070698  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
129070839  CDS2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
129070855  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
129070857  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
129071087  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
129072720  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
129073011  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
129073361  OCRL; inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
129073507  MTMR6; myotubularin-related protein 6 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
129074166  SYNJ1; synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
129074299  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
129074590  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
129074969  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
129075160  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
129075675  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
129075818  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
129076577  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
129076632  ITPKC; inositol-trisphosphate 3-kinase C isoform X1 [KO:K00911] [EC:2.7.1.127]
129076731  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
129077085  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
129077217  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
129077405  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
129077408  MTM1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
129077474  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
129077560  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
129078059  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
129078278  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
129078690  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
129078752  CALML6; calmodulin-like protein 6 [KO:K02183]
129079548  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV isoform X1 [KO:K20278] [EC:3.1.3.36]
129079701  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
129079854  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
129080164  DGKE; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
129080179  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
129080346  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
129080532  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
129080641  INPP4A; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
129080888  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
129081449  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
129081586  PRKCG; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
129081665  IMPA2; inositol monophosphatase 2 isoform X1 [KO:K01092] [EC:3.1.3.25]
129082334  IPPK; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
129082875  CALM3; calmodulin-3 [KO:K02183]
129083928  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
129084147  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
129084580  [KO:K02183]
129084594  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
129084779  DGKA; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
129084965  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
129084992  PIK3C2G; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
129085381  CDS1; phosphatidate cytidylyltransferase 1 isoform X1 [KO:K00981] [EC:2.7.7.41]
129086029  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
129086251  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
129086282  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
129086576  [KO:K02183]
129086629  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
129086971  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
129087301  CALML3; calmodulin-like protein 3 [KO:K02183]
129087376  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
129087625  IP6K2; inositol hexakisphosphate kinase 2 isoform X1 [KO:K07756] [EC:2.7.4.21]
129087685  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
129087694  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
129087754  SACM1L; LOW QUALITY PROTEIN: phosphatidylinositol-3-phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
129087884  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
129088253  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
129088291  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
129088362  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
129088427  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [KO:K05857] [EC:3.1.4.11]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
ppam04020  Calcium signaling pathway
ppam04144  Endocytosis
ppam04151  PI3K-Akt signaling pathway
ppam04510  Focal adhesion
KO pathway
ko04070   

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