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Entry |
Name |
Definition |
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N00317
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AhR signaling pathway
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KA → (AHR+ARNT) ⇒ (IL6,IL22,PTGS2,VEGFA,CYP1A1,CYP1B1)
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N00318
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EGFR-ERK-ACTH signaling pathway
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EGFR → ERK1/2 → ACTH
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N00319
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Mutation-activated USP8 to EGFR-ERK-ACTH signaling pathway
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USP8* → EGFR → ERK1/2 → ACTH
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N00320
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Mutation-activated PRKACA to ACTH-cortisol signaling pathway
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PRKACA* → (NR5A1,NR4A1,SP1,PBX1,CREB) ⇒ (STAR,CYP11B1) → Cortisol
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N00321
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Mutation-activated GNAS to ACTH-cortisol signaling pathway
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GNAS* → ADCY → cAMP → PKA → (NR5A1,NR4A1,SP1,PBX1,CREB) ⇒ (STAR,CYP11B1) → Cortisol
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N00322
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Mutation-inactivated PRKAR1A to ACTH-cortisol signaling pathway
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(PRKAR1A*+PRKACA) → (NR5A1,NR4A1,SP1,PBX1,CREB) ⇒ (STAR,CYP11B1) → Cortisol
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N00323
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Mutation-inactivated PDE11A/PDE8B to ACTH-cortisol signaling pathway
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(PDE11A*,PDE8B*) ⌿ cAMP → (PRKAR1A+PRKACA) → (NR5A1,NR4A1,SP1,PBX1,CREB) ⇒ (STAR,CYP11B1) → Cortisol
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N00324
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CRHR-PKA-ACTH signaling pathway
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CRH → CRHR → GNAS → ADCY → cAMP → PKA → CREB → ACTH
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N00325
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Mutation-inactivated RASD1 to CRHR-PKA-ACTH signaling pathway
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RASD1* ⌿ GNAI ⌿ ADCY → cAMP → PKA → CREB → ACTH
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N00326
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Mutation-activated GNAS to CRHR-PKA-ACTH signaling pathway
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GNAS* → ADCY → cAMP → PKA → CREB → ACTH
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N00327
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Mutation-inactivated PRKAR1A to CRHR-PKA-ACTH signaling pathway
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CRH → CRHR → GNAS → ADCY → cAMP → (PRKAR1A*+PRKACA) → CREB → ACTH
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N00332
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Vesicular uptake of lipoproteins
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APOB → LDLR == LDLRAP1
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N00336
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PCSK9-mediated LDLR degradation
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PCSK9 ⊣ LDLR
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N00338
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Steroid hormone biosynthesis, progesterone to cortisol/cortisone
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Progesterone — CYP17A1 ⇛ CYP21A2 ⇛ CYP11B1/2 → Cortisol — HSD11B2 → Cortisone
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N00339
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Steroid hormone biosynthesis, progesterone to aldosterone
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Progesterone — CYP21A2 ⇛ CYP11B1 ⇛ CYP11B2 → Aldosterone
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N00340
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The Scribble/Dlg/Lgl polarity module
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LLGL == SCRIB == DLG1
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N00341
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HPV E6 to the Scribble/Dlg/Lgl polarity module
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(E6+UBE3A) ⊣ (DLG1+SCRIB)
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N00342
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MAGI-PTEN signaling pathway
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MAGI → PTEN ⊣ PIP3 → AKT
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N00343
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HPV E6 to MAGI-PTEN signaling pathway
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(E6+UBE3A) ⊣ MAGI1
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N00344
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CRB3-Pals1-PATJ complex
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CRB3 == MPP5 == PATJ
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N00345
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HPV E6 to CRB3-Pals1-PATJ complex
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(E6+UBE3A) ⊣ PATJ
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N00346
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HPV E6 to TLR-IRF3 signaling pathway
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E6 ⊣ IRF3
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N00347
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p300-p21-Cell cycle G1/S
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(ATM,ATR) → TADA3 → EP300 → TP53 ⇒ CDKN1A ⊣ (CCND+CDK4/6) → RB1 ⌿ E2F
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N00348
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HPV E6 to p300-p21-Cell cycle G1/S
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E6 ⊣ EP300
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N00349
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HPV E6 to p300-p21-Cell cycle G1/S
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E6 ⊣ TADA3
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N00350
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HPV E6 to extrinsic apoptotic pathway
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E6 ⊣ TNFRSF1A
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N00351
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HPV E6 to extrinsic apoptotic pathway
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E6 ⊣ FADD
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N00352
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HPV E6 to extrinsic apoptotic pathway
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E6 ⊣ CASP8
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N00353
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HPV E6 to PTEN-PIP3-AKT signaling pathway
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E6 ⊣ SLC9A3R1 → PTEN
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N00354
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HPV E6 to PTEN-PIP3-AKT signaling pathway
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E6 ⊣ PTEN
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N00355
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PP2A-AKT signaling pathway
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PP2A ⊣ AKT
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N00356
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HPV E7 to PP2A-AKT signaling patyway
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E7 ⊣ PP2A
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N00357
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HPV E6 to MTOR signaling pathway
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(E6+UBE3A) ⊣ (TSC1+TSC2)
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N00358
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HPV E6 to p21-cell cycle G1/S
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(E6+UBE3A) ⊣ TP53
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N00359
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HPV E7 to p27-cell cycle G1/S
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E7 ⊣ (CDKN1A,CDKN1B)
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N00360
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HPV E7 to p27-cell cycle G1/S
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E7 → (CCNE+CDK2) → RB1 ⌿ E2F
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N00361
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HPV E7 to cell cycle G1/S
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E7 → (RB1,RBL1,RBL2) ⌿ E2F
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N00362
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HPV E5 to p21-cell cycle G1/S
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E5 ⊣ (CDKN1A,CDKN1B)
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N00363
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Antigen processing and presentation by MHC class I molecules
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TAP1/2 == TAPBP == (PDIA3+CALR) → (MHCI+B2M)
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N00364
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HPV E5 to antigen processing and presentation by MHC class I molecules
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E5 ⊣ (MHCI+BCAP31)
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